MX2020011341A - Una composicion para el tratamiento de una o mas enfermedades relacionadas con los estrogenos. - Google Patents

Una composicion para el tratamiento de una o mas enfermedades relacionadas con los estrogenos.

Info

Publication number
MX2020011341A
MX2020011341A MX2020011341A MX2020011341A MX2020011341A MX 2020011341 A MX2020011341 A MX 2020011341A MX 2020011341 A MX2020011341 A MX 2020011341A MX 2020011341 A MX2020011341 A MX 2020011341A MX 2020011341 A MX2020011341 A MX 2020011341A
Authority
MX
Mexico
Prior art keywords
composition
treating
related diseases
estrogen
patient
Prior art date
Application number
MX2020011341A
Other languages
English (en)
Inventor
Finn Larsen
Carol Marion Maclean
Original Assignee
Lifearc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifearc filed Critical Lifearc
Publication of MX2020011341A publication Critical patent/MX2020011341A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere al tratamiento de una o más enfermedades relacionadas con los estrógenos mientras se previene o se reduce la probabilidad de desarrollar efectos secundarios relacionados con la deficiencia de estrógenos, en donde dicha composición comprende administrar una cantidad terapéuticamente eficaz de un antagonista de GnRH a un paciente que necesita dicho tratamiento, y en donde dicha cantidad de antagonista de GnRH es suficiente para proporcionar un nivel medio de estradiol sérico endógeno de entre aproximadamente 20 pg/ml y 60 pg/ml, preferiblemente entre 30 pg/ml y 50 pg/ml, en dicho paciente en un período de tratamiento de por lo menos cuatro semanas, sin depender de la terapia de "adición". Dicha composición y método es simple, eficaz y, en consecuencia, aumentará tanto la aceptación del paciente como el cumplimiento de la terapia.
MX2020011341A 2018-04-26 2019-04-25 Una composicion para el tratamiento de una o mas enfermedades relacionadas con los estrogenos. MX2020011341A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18169419.1A EP3560555A1 (en) 2018-04-26 2018-04-26 A composition for treating one or more estrogen related diseases
PCT/EP2019/060570 WO2019207026A1 (en) 2018-04-26 2019-04-25 A composition for treating one or more estrogen related diseases

Publications (1)

Publication Number Publication Date
MX2020011341A true MX2020011341A (es) 2020-11-24

Family

ID=62067442

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020011341A MX2020011341A (es) 2018-04-26 2019-04-25 Una composicion para el tratamiento de una o mas enfermedades relacionadas con los estrogenos.

Country Status (12)

Country Link
US (1) US11446351B2 (es)
EP (2) EP3560555A1 (es)
JP (1) JP2021522227A (es)
KR (1) KR20210003868A (es)
CN (1) CN112041028A (es)
AU (1) AU2019258514A1 (es)
BR (1) BR112020021565A2 (es)
CA (1) CA3097267A1 (es)
IL (1) IL277876A (es)
MA (1) MA52359A (es)
MX (1) MX2020011341A (es)
WO (1) WO2019207026A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3590525A1 (en) * 2018-07-05 2020-01-08 Antev Limited Teverelix-tfa composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681817A (en) * 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
EP0769956B1 (en) * 1994-07-22 2000-03-15 The Medical College Of Hampton Roads USE OF A GnRH ANTAGONIST FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF GONADAL-STEROID CONDITIONS
US5658884A (en) * 1994-07-22 1997-08-19 The Medical College Of Hampton Roads Establishment of tonic ovarian estrogen secretion for extended therapeutic regimens
EP1214086A2 (en) * 1999-09-23 2002-06-19 Zentaris AG Method for the therapeutic management of endometriosis and fallopian tube obstruction
US7005418B1 (en) * 1999-09-23 2006-02-28 Zentaris Gmbh Method for the therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction
JP2004529207A (ja) * 2001-04-30 2004-09-24 ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング Lhrhアンタゴニストの中間の用量での痴呆及び神経変性疾患の治療
GB0117057D0 (en) * 2001-07-12 2001-09-05 Ferring Bv Pharmaceutical composition
US7098305B2 (en) 2001-09-06 2006-08-29 Ardana Bioscience Limited Sustained release of microcrystalline peptide suspensions
WO2008071984A1 (en) * 2006-12-13 2008-06-19 Ardana Bioscience Limited Administration of the gonadotropin-releasing hormone antagonist teverelix

Also Published As

Publication number Publication date
CA3097267A1 (en) 2019-10-31
MA52359A (fr) 2021-03-03
JP2021522227A (ja) 2021-08-30
AU2019258514A1 (en) 2020-10-22
US20210052692A1 (en) 2021-02-25
EP3784346A1 (en) 2021-03-03
IL277876A (en) 2020-11-30
WO2019207026A1 (en) 2019-10-31
KR20210003868A (ko) 2021-01-12
EP3560555A1 (en) 2019-10-30
US11446351B2 (en) 2022-09-20
BR112020021565A2 (pt) 2021-01-19
CN112041028A (zh) 2020-12-04

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