JP2009530410A5 - - Google Patents

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Publication number
JP2009530410A5
JP2009530410A5 JP2009501610A JP2009501610A JP2009530410A5 JP 2009530410 A5 JP2009530410 A5 JP 2009530410A5 JP 2009501610 A JP2009501610 A JP 2009501610A JP 2009501610 A JP2009501610 A JP 2009501610A JP 2009530410 A5 JP2009530410 A5 JP 2009530410A5
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JP
Japan
Prior art keywords
alkyl
heteroaryl
saturated
aryl
heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2009501610A
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English (en)
Japanese (ja)
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JP2009530410A (ja
JP5377284B2 (ja
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Priority claimed from PCT/US2007/007444 external-priority patent/WO2007117381A2/en
Publication of JP2009530410A publication Critical patent/JP2009530410A/ja
Publication of JP2009530410A5 publication Critical patent/JP2009530410A5/ja
Application granted granted Critical
Publication of JP5377284B2 publication Critical patent/JP5377284B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009501610A 2006-03-24 2007-03-23 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ Expired - Fee Related JP5377284B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78546006P 2006-03-24 2006-03-24
US60/785,460 2006-03-24
PCT/US2007/007444 WO2007117381A2 (en) 2006-03-24 2007-03-23 2 -aminopyridine analogs as glucokinase activators

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013171956A Division JP2013245220A (ja) 2006-03-24 2013-08-22 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ

Publications (3)

Publication Number Publication Date
JP2009530410A JP2009530410A (ja) 2009-08-27
JP2009530410A5 true JP2009530410A5 (https=) 2011-04-28
JP5377284B2 JP5377284B2 (ja) 2013-12-25

Family

ID=38542984

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009501610A Expired - Fee Related JP5377284B2 (ja) 2006-03-24 2007-03-23 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ
JP2013171956A Withdrawn JP2013245220A (ja) 2006-03-24 2013-08-22 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013171956A Withdrawn JP2013245220A (ja) 2006-03-24 2013-08-22 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ

Country Status (25)

Country Link
US (3) US8022223B2 (https=)
EP (2) EP2013204B1 (https=)
JP (2) JP5377284B2 (https=)
KR (1) KR101440634B1 (https=)
CN (1) CN101437816B (https=)
AU (1) AU2007235558B2 (https=)
BR (1) BRPI0709171A2 (https=)
CA (1) CA2647208C (https=)
DK (1) DK2013204T3 (https=)
ES (1) ES2536547T3 (https=)
HR (1) HRP20150347T1 (https=)
IL (1) IL194160A (https=)
MX (1) MX2008012168A (https=)
MY (1) MY148985A (https=)
NZ (1) NZ571997A (https=)
PL (1) PL2013204T3 (https=)
PT (1) PT2013204E (https=)
RS (1) RS53981B1 (https=)
RU (1) RU2457207C2 (https=)
SG (1) SG170775A1 (https=)
SI (1) SI2013204T1 (https=)
TW (1) TWI393718B (https=)
UA (1) UA103746C2 (https=)
WO (1) WO2007117381A2 (https=)
ZA (1) ZA200809017B (https=)

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RU2457207C2 (ru) 2006-03-24 2012-07-27 Эррэй Биофарма Инк. Активаторы глюкокиназы
WO2008091770A1 (en) * 2007-01-24 2008-07-31 Array Biopharma Inc. 2-aminopyridine derivatives as glucokinase activators
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EP2573087A1 (en) * 2007-09-21 2013-03-27 Array Biopharma, Inc. Pyridin-2-yl-amino-1,2,4-thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus
BRPI0818658A2 (pt) * 2007-10-09 2015-04-14 Merck Patent Ges Mit Beschränkter Haftung Derivados de piridina úteis como ativadores de glicoquinase
PT2239253E (pt) * 2008-02-06 2013-09-17 Daiichi Sankyo Co Ltd Novo derivado de fenilpirrole
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
CN102959076B (zh) 2010-03-31 2015-09-16 斯克里普斯研究所 重编程细胞
US8178689B2 (en) 2010-06-17 2012-05-15 Hoffman-La Roche Inc. Tricyclic compounds
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2766349B1 (de) 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120056A1 (de) 2011-03-08 2012-09-13 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
JPWO2012121314A1 (ja) 2011-03-09 2014-07-17 第一三共株式会社 ジピリジルアミン誘導体
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
CA2877026A1 (en) 2012-05-18 2013-11-21 Amgen Inc. Method for the preparation of thiadiazoles
EP2917213A1 (en) * 2012-11-09 2015-09-16 Array Biopharma, Inc. Crystalline forms of (1s)-1-[5-({3-[(2-methylpyridin-3-yl)oxy]-5-(pyridin-2-ylsulfanyl)pyridin-2-yl}amino)-1,2,4-thiadiazol-3-yl]ethane-1,2-diol
JP6618901B2 (ja) * 2013-11-13 2019-12-11 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ インフルエンザウイルスの複製の阻害剤を調製する方法
WO2017093120A1 (en) 2015-12-01 2017-06-08 Basf Se Pyridine compounds as fungicides
EP3383849B1 (en) 2015-12-01 2020-01-08 Basf Se Pyridine compounds as fungicides
CN108329330B (zh) * 2017-01-20 2021-05-04 复旦大学 2-苄氧苯基噁唑并吡啶类化合物及其药物用途
CR20190580A (es) 2017-05-30 2020-02-10 Basf Se Compuestos de piridina y pirazina
GB201714777D0 (en) 2017-09-14 2017-11-01 Univ London Queen Mary Agent
SG11202003879RA (en) 2017-10-30 2020-05-28 Neuropore Therapies Inc Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof
WO2020051424A1 (en) 2018-09-07 2020-03-12 Pic Therapeutics Eif4e inhibitors and uses thereof
EP4077276A1 (en) 2019-12-19 2022-10-26 Curia Spain S.A.U. Process and intermediates for the preparation of upadacitinib
TW202146393A (zh) 2020-03-03 2021-12-16 美商皮克醫療公司 Eif4e抑制劑及其用途
CA3229560A1 (en) 2021-08-25 2023-03-02 Christopher L. Vandeusen Eif4e inhibitors and uses thereof
US12157732B2 (en) 2021-08-25 2024-12-03 PIC Therapeutics, Inc. eIF4E inhibitors and uses thereof

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US6846928B2 (en) 2002-03-15 2005-01-25 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
NZ540791A (en) * 2003-02-13 2009-09-25 Banyu Pharma Co Ltd Novel 2-pyridinecarboxamide derivatives
AR049418A1 (es) 2004-02-27 2006-08-02 Bayer Pharmaceuticals Corp Derivados de heteroarilaminopirazol y composiciones farmaceuticas para el tratamiento de la diabetes.
US7687502B2 (en) 2004-03-23 2010-03-30 Banyu Pharmaceutical Co., Ltd. Substituted quinazoline or pyridopyrimidine derivative
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RU2457207C2 (ru) 2006-03-24 2012-07-27 Эррэй Биофарма Инк. Активаторы глюкокиназы

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