JP2009530410A5 - - Google Patents

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Publication number
JP2009530410A5
JP2009530410A5 JP2009501610A JP2009501610A JP2009530410A5 JP 2009530410 A5 JP2009530410 A5 JP 2009530410A5 JP 2009501610 A JP2009501610 A JP 2009501610A JP 2009501610 A JP2009501610 A JP 2009501610A JP 2009530410 A5 JP2009530410 A5 JP 2009530410A5
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JP
Japan
Prior art keywords
alkyl
heteroaryl
saturated
aryl
heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2009501610A
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English (en)
Japanese (ja)
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JP2009530410A (ja
JP5377284B2 (ja
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Publication date
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Priority claimed from PCT/US2007/007444 external-priority patent/WO2007117381A2/en
Publication of JP2009530410A publication Critical patent/JP2009530410A/ja
Publication of JP2009530410A5 publication Critical patent/JP2009530410A5/ja
Application granted granted Critical
Publication of JP5377284B2 publication Critical patent/JP5377284B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009501610A 2006-03-24 2007-03-23 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ Expired - Fee Related JP5377284B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78546006P 2006-03-24 2006-03-24
US60/785,460 2006-03-24
PCT/US2007/007444 WO2007117381A2 (en) 2006-03-24 2007-03-23 2 -aminopyridine analogs as glucokinase activators

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013171956A Division JP2013245220A (ja) 2006-03-24 2013-08-22 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ

Publications (3)

Publication Number Publication Date
JP2009530410A JP2009530410A (ja) 2009-08-27
JP2009530410A5 true JP2009530410A5 (https=) 2011-04-28
JP5377284B2 JP5377284B2 (ja) 2013-12-25

Family

ID=38542984

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009501610A Expired - Fee Related JP5377284B2 (ja) 2006-03-24 2007-03-23 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ
JP2013171956A Withdrawn JP2013245220A (ja) 2006-03-24 2013-08-22 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013171956A Withdrawn JP2013245220A (ja) 2006-03-24 2013-08-22 グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ

Country Status (25)

Country Link
US (3) US8022223B2 (https=)
EP (2) EP2543667B1 (https=)
JP (2) JP5377284B2 (https=)
KR (1) KR101440634B1 (https=)
CN (1) CN101437816B (https=)
AU (1) AU2007235558B2 (https=)
BR (1) BRPI0709171A2 (https=)
CA (1) CA2647208C (https=)
DK (1) DK2013204T3 (https=)
ES (1) ES2536547T3 (https=)
HR (1) HRP20150347T1 (https=)
IL (1) IL194160A (https=)
MX (1) MX2008012168A (https=)
MY (1) MY148985A (https=)
NZ (1) NZ571997A (https=)
PL (1) PL2013204T3 (https=)
PT (1) PT2013204E (https=)
RS (1) RS53981B1 (https=)
RU (1) RU2457207C2 (https=)
SG (1) SG170775A1 (https=)
SI (1) SI2013204T1 (https=)
TW (1) TWI393718B (https=)
UA (1) UA103746C2 (https=)
WO (1) WO2007117381A2 (https=)
ZA (1) ZA200809017B (https=)

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RS53981B1 (sr) 2006-03-24 2015-10-30 Array Biopharma Inc. Analozi 2-aminopiridina kao aktivatori glukokinaze
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AU2008305294B2 (en) * 2007-09-21 2012-11-29 Array Biopharma Inc. Pyridin-2 -yl-amino-1, 2, 4 -thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus
JP5567481B2 (ja) * 2007-10-09 2014-08-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング グルコキナーゼアクチベーターとして有用なピリジン誘導体
PT2239253E (pt) * 2008-02-06 2013-09-17 Daiichi Sankyo Co Ltd Novo derivado de fenilpirrole
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
CA2800498C (en) 2010-03-31 2021-11-16 The Scripps Research Institute Reprogramming cells
US8178689B2 (en) 2010-06-17 2012-05-15 Hoffman-La Roche Inc. Tricyclic compounds
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
JPWO2012121314A1 (ja) 2011-03-09 2014-07-17 第一三共株式会社 ジピリジルアミン誘導体
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013173672A1 (en) 2012-05-18 2013-11-21 Array Biopharma Inc. Method for the preparation of thiadiazoles
EP2917213A1 (en) * 2012-11-09 2015-09-16 Array Biopharma, Inc. Crystalline forms of (1s)-1-[5-({3-[(2-methylpyridin-3-yl)oxy]-5-(pyridin-2-ylsulfanyl)pyridin-2-yl}amino)-1,2,4-thiadiazol-3-yl]ethane-1,2-diol
HRP20181272T1 (hr) * 2013-11-13 2018-10-05 Vertex Pharmaceuticals Incorporated Postupci priprave inhibitora replikacije virusa influence
EP3383848B1 (en) 2015-12-01 2020-01-08 Basf Se Pyridine compounds as fungicides
CN108290840A (zh) 2015-12-01 2018-07-17 巴斯夫欧洲公司 作为杀真菌剂的吡啶化合物
CN108329330B (zh) * 2017-01-20 2021-05-04 复旦大学 2-苄氧苯基噁唑并吡啶类化合物及其药物用途
EA201992764A1 (ru) 2017-05-30 2020-04-29 Басф Се Пиридиновые и пиразиновые соединения
GB201714777D0 (en) 2017-09-14 2017-11-01 Univ London Queen Mary Agent
EP3703675A4 (en) 2017-10-30 2021-06-16 Neuropore Therapies, Inc. SUBSTITUTED PHENYLSULFONYLPHÉNYLTRIAZOLETHIONES AND ASSOCIATED USES
US12030875B2 (en) 2018-09-07 2024-07-09 PIC Therapeutics, Inc. EIF4E inhibitors and uses thereof
US12552746B2 (en) 2019-12-19 2026-02-17 Curia Spain, S.A.U. Process and intermediates for the preparation of upadacitinib
AU2021230289A1 (en) 2020-03-03 2022-09-29 PIC Therapeutics, Inc. eIF4E inhibitors and uses thereof
US12157732B2 (en) 2021-08-25 2024-12-03 PIC Therapeutics, Inc. eIF4E inhibitors and uses thereof
JP2024534127A (ja) 2021-08-25 2024-09-18 ピク セラピューティクス， インコーポレイテッド ｅＩＦ４Ｅ阻害剤及びその使用

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US20050043545A1 (en) 2001-11-02 2005-02-24 Gianpalol Bravi 4-(5-Membered)-heteroaryl acyl pyrrolidine derivatives as hcv inhibitors
WO2003062224A1 (en) 2002-01-17 2003-07-31 Eli Lilly And Company Aza-cyclic compounds as modulators of acetylcholine receptors
WO2003078423A1 (en) * 2002-03-15 2003-09-25 Vertex Pharmaceuticals, Inc. Compositions useful as inhibitors of protein kinases
EP1598349B1 (en) * 2003-02-13 2011-07-27 Msd K.K. Novel 2-pyridinecarboxamide derivatives
AR049418A1 (es) * 2004-02-27 2006-08-02 Bayer Pharmaceuticals Corp Derivados de heteroarilaminopirazol y composiciones farmaceuticas para el tratamiento de la diabetes.
EP1734040A4 (en) * 2004-03-23 2007-11-28 Banyu Pharma Co Ltd SUBSTITUTED CHINAZOLINE OR PYRIDOPYRIMIDINE DERIVATIVE
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RS53981B1 (sr) 2006-03-24 2015-10-30 Array Biopharma Inc. Analozi 2-aminopiridina kao aktivatori glukokinaze

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