JP2009528828A5 - - Google Patents
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- Publication number
- JP2009528828A5 JP2009528828A5 JP2008557594A JP2008557594A JP2009528828A5 JP 2009528828 A5 JP2009528828 A5 JP 2009528828A5 JP 2008557594 A JP2008557594 A JP 2008557594A JP 2008557594 A JP2008557594 A JP 2008557594A JP 2009528828 A5 JP2009528828 A5 JP 2009528828A5
- Authority
- JP
- Japan
- Prior art keywords
- less
- antibody
- rsv
- nucleic acid
- encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000007523 nucleic acids Chemical group 0.000 claims 18
- 210000004027 cell Anatomy 0.000 claims 17
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 15
- 239000012634 fragment Substances 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 230000009257 reactivity Effects 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 108091006027 G proteins Proteins 0.000 claims 7
- 102000030782 GTP binding Human genes 0.000 claims 7
- 108091000058 GTP-Binding Proteins 0.000 claims 7
- 239000013598 vector Substances 0.000 claims 6
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 5
- 108091007433 antigens Proteins 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 101710132601 Capsid protein Proteins 0.000 claims 4
- 101710094648 Coat protein Proteins 0.000 claims 4
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 claims 4
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 4
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 4
- 101710125418 Major capsid protein Proteins 0.000 claims 4
- 101710141454 Nucleoprotein Proteins 0.000 claims 4
- 101710083689 Probable capsid protein Proteins 0.000 claims 4
- 206010061603 Respiratory syncytial virus infection Diseases 0.000 claims 4
- 230000037396 body weight Effects 0.000 claims 4
- 235000018102 proteins Nutrition 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 claims 3
- 230000028996 humoral immune response Effects 0.000 claims 3
- 108091026890 Coding region Proteins 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 2
- 238000004458 analytical method Methods 0.000 claims 2
- 230000008878 coupling Effects 0.000 claims 2
- 238000010168 coupling process Methods 0.000 claims 2
- 238000005859 coupling reaction Methods 0.000 claims 2
- 238000010494 dissociation reaction Methods 0.000 claims 2
- 230000005593 dissociations Effects 0.000 claims 2
- 238000002955 isolation Methods 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 230000005030 transcription termination Effects 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 235000001014 amino acid Nutrition 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 210000004698 lymphocyte Anatomy 0.000 claims 1
- 238000007857 nested PCR Methods 0.000 claims 1
- 230000003472 neutralizing effect Effects 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 210000004180 plasmocyte Anatomy 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 238000003259 recombinant expression Methods 0.000 claims 1
- 238000003757 reverse transcription PCR Methods 0.000 claims 1
- 239000003981 vehicle Substances 0.000 claims 1
- 239000013603 viral vector Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200600324 | 2006-03-06 | ||
| US87471606P | 2006-12-14 | 2006-12-14 | |
| PCT/DK2007/000113 WO2007101441A1 (en) | 2006-03-06 | 2007-03-06 | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009528828A JP2009528828A (ja) | 2009-08-13 |
| JP2009528828A5 true JP2009528828A5 (enExample) | 2011-04-28 |
Family
ID=38230163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008557594A Withdrawn JP2009528828A (ja) | 2006-03-06 | 2007-03-06 | 消化器多核体ウイルス感染症の治療のための組み換えポリクローナル抗体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20100040606A1 (enExample) |
| EP (1) | EP2004686A1 (enExample) |
| JP (1) | JP2009528828A (enExample) |
| KR (1) | KR20080113223A (enExample) |
| CN (1) | CN101395182A (enExample) |
| AU (1) | AU2007222798A1 (enExample) |
| BR (1) | BRPI0708636A2 (enExample) |
| CA (1) | CA2638833A1 (enExample) |
| IL (1) | IL193386A0 (enExample) |
| MX (1) | MX2008011280A (enExample) |
| WO (1) | WO2007101441A1 (enExample) |
| ZA (1) | ZA200806362B (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2512647C (en) | 2003-01-07 | 2013-10-08 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
| RU2426795C2 (ru) | 2004-07-20 | 2011-08-20 | Симфоген А/С | Способ структурной характеристики рекомбинантного поликлонального белка или поликлональной клеточной линии |
| JP2009518320A (ja) * | 2005-12-05 | 2009-05-07 | シュムフォウエン アクティーゼルスカブ | 抗オルトポックスウイルス組換えポリクローナル抗体 |
| EP2502628B1 (en) * | 2006-06-23 | 2016-12-14 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in cancer |
| PL2132229T3 (pl) | 2007-03-01 | 2016-12-30 | Kompozycje rekombinowanych przeciwciał anty-receptor czynnika wzrostu naskórka | |
| MX2009008908A (es) | 2007-03-01 | 2009-08-28 | Symphogen As | Metodo para clonacion de anticuerpos analogos. |
| CN101679513A (zh) * | 2007-03-06 | 2010-03-24 | 西福根有限公司 | 用于治疗呼吸道合胞病毒感染的重组抗体 |
| NZ581316A (en) | 2007-05-25 | 2012-02-24 | Symphogen As | Method for manufacturing a recombinant polyclonal protein |
| JP2008289483A (ja) * | 2007-05-25 | 2008-12-04 | Symphogen As | 真核生物系において発現可能な形質転換体のスクリーニング |
| CN101821289A (zh) * | 2007-09-07 | 2010-09-01 | 西福根有限公司 | 重组制造抗rsv抗体的方法 |
| WO2009042589A1 (en) * | 2007-09-24 | 2009-04-02 | Vanderbilt University | Monoclonal antibodies to respiratory syncytial virus and uses thereof |
| NZ585589A (en) * | 2007-10-25 | 2012-07-27 | Trellis Bioscience Inc | Anti-rsv g protein antibodies |
| EP2331577B1 (en) | 2008-08-29 | 2017-06-07 | Symphogen A/S | Recombinant anti-epidermal growth factor receptor antibody compositions |
| AU2009301505A1 (en) * | 2008-10-06 | 2010-04-15 | Symphogen A/S | Method for identifying and selecting drug candidates for combinatorial drug products |
| WO2010060186A1 (en) | 2008-11-03 | 2010-06-03 | Alethia Biotherapeutics Inc. | Antibodies that specifically block the biological activity of a tumor antigen |
| GB2483810B (en) | 2008-11-07 | 2012-09-05 | Sequenta Inc | Methods for correlating clonotypes with diseases in a population |
| US8691510B2 (en) * | 2008-11-07 | 2014-04-08 | Sequenta, Inc. | Sequence analysis of complex amplicons |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| PT2387627E (pt) | 2009-01-15 | 2016-06-03 | Adaptive Biotechnologies Corp | Determinação do perfil de imunidade adaptativa e métodos de geração de anticorpos monoclonais |
| JP2012531202A (ja) | 2009-06-25 | 2012-12-10 | フレッド ハチンソン キャンサー リサーチ センター | 適応免疫を測定する方法 |
| CN103977394B (zh) * | 2009-07-17 | 2016-03-09 | 翰林大学校产学协力团 | 包含脂质体包胶的寡核苷酸和表位的免疫刺激性组合物 |
| JP2013507603A (ja) | 2009-10-09 | 2013-03-04 | シムフォゲン・アクティーゼルスカブ | 署名ペプチドおよび質量分析による混合物中の個々の組換えタンパク質の多重定量化 |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| CA3062786C (en) * | 2010-07-09 | 2022-04-19 | Janssen Vaccines & Prevention B.V. | Anti-human respiratory syncytial virus (rsv) antibodies and methods of use |
| EP2625295B1 (en) * | 2010-10-08 | 2019-03-13 | President and Fellows of Harvard College | High-throughput immune sequencing |
| CA2824389A1 (en) * | 2011-01-10 | 2012-07-19 | Emory University | Antibodies directed against influenza |
| DK3173427T3 (da) | 2011-03-31 | 2019-08-05 | Adc Therapeutics Sa | Antistoffer mod nyre-associeret antigen 1 og antigen-bindende fragmenter deraf |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| EP2768982A4 (en) | 2011-10-21 | 2015-06-03 | Adaptive Biotechnologies Corp | QUANTIFICATION OF ADAPTIVE IMMUNOCELL GENOMES IN A COMPLEX MIX OF CELLS |
| AU2012347460B2 (en) | 2011-12-09 | 2017-05-25 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| HRP20190946T1 (hr) | 2012-01-09 | 2019-07-26 | Adc Therapeutics Sa | Sredstva za liječenje trostruko negativnog raka dojke |
| US9546219B2 (en) | 2012-02-08 | 2017-01-17 | North Carolina State University | Treatment of allergic diseases with recombinant antibodies |
| JP6302847B2 (ja) | 2012-03-05 | 2018-03-28 | アダプティヴ バイオテクノロジーズ コーポレーション | 頻度が一致したサブユニットからの、対をなす免疫受容体鎖の決定 |
| ES2711156T3 (es) | 2012-05-08 | 2019-04-30 | Adaptive Biotechnologies Corp | Método para medir y calibrar el sesgo de amplificación en reacciones de PCR multiplexadas |
| PT2887959T (pt) * | 2012-08-23 | 2019-02-01 | Seattle Genetics Inc | Conjugados anticorpo-fármaco (adc) que se ligam a proteínas 158p1d7 |
| EP2904111B1 (en) | 2012-10-01 | 2017-12-06 | Adaptive Biotechnologies Corporation | Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization |
| CA2890427C (en) | 2012-11-06 | 2022-05-31 | Medimmune, Llc | Antibodies to s. aureus surface determinants |
| TWI659968B (zh) * | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒ｆ蛋白質的人類抗體及其使用方法 |
| US10119134B2 (en) | 2013-03-15 | 2018-11-06 | Abvitro Llc | Single cell bar-coding for antibody discovery |
| CN103196731A (zh) * | 2013-04-18 | 2013-07-10 | 王刚平 | 用于鉴别乳腺肌上皮病变的多重染色试剂及其检测方法 |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| US20170292149A1 (en) | 2014-03-05 | 2017-10-12 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| ES2777529T3 (es) | 2014-04-17 | 2020-08-05 | Adaptive Biotechnologies Corp | Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células |
| SG10201911069WA (en) | 2014-09-15 | 2020-01-30 | Abvitro Llc | High-throughput nucleotide library sequencing |
| NZ729808A (en) | 2014-09-30 | 2022-02-25 | Neurimmune Holding Ag | Human-derived anti-dipeptide repeats (dprs) antibody |
| US11725044B2 (en) | 2014-10-15 | 2023-08-15 | Xenothera | Method for producing polyclonal antibodies with improved complement-dependent cytotoxicity |
| WO2016069886A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corporation | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| CA2968543C (en) | 2014-11-25 | 2024-04-02 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| WO2016138122A1 (en) | 2015-02-24 | 2016-09-01 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
| WO2016161273A1 (en) | 2015-04-01 | 2016-10-06 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
| WO2018052789A1 (en) * | 2016-09-08 | 2018-03-22 | Pcm Targetech, Llc | Monoclonal antibodies specific to the plexin-semaphorin-integrin (psi) domain of ron for drug delivery and its application in cancer therapy |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| EP3538558A4 (en) | 2016-11-09 | 2020-07-15 | North Carolina State University | TREATMENT OF ALLERGIC DISEASES USING CHIMERIC PROTEIN |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| WO2019165019A1 (en) * | 2018-02-21 | 2019-08-29 | Vanderbilt University | Antibodies to human respiratory syncytial virus protein f pre-fusion conformation and methods of use therefor |
| WO2019183437A1 (en) | 2018-03-23 | 2019-09-26 | North Carolina State University | Methods and compositions for antibody to high affinity receptor for ige |
| JP2021521896A (ja) | 2018-04-27 | 2021-08-30 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | ヒト由来の抗（ポリｇａ）ジペプチドリピート（ｄｐｒ）抗体 |
| US20220025019A1 (en) * | 2018-11-30 | 2022-01-27 | Csl Behring Ag | Methods and compositions for preventing or treating acute exacerbations with polyclonal immunoglobulin |
| AU2020264492A1 (en) * | 2019-04-30 | 2021-10-14 | Gigagen, Inc. | Recombinant polyclonal proteins and methods of use thereof |
| CA3177152A1 (en) | 2020-06-12 | 2021-12-16 | David Scott Johnson | Recombinant polyclonal proteins targeting covid-19 and methods of use thereof |
| JP2024508222A (ja) * | 2021-01-29 | 2024-02-26 | アムジエン・インコーポレーテツド | 抗Ｍｃｌ１抗体を投与することによる癌を監視するための材料及び方法 |
| CN113249333B (zh) * | 2021-03-16 | 2023-06-02 | 贵州省人民医院 | 一种分泌抗呼吸道合胞病毒单克隆抗体的杂交瘤细胞株rsvn4c3 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4767610A (en) * | 1984-10-19 | 1988-08-30 | The Regents Of The University Of California | Method for detecting abnormal cell masses in animals |
| US5639853A (en) * | 1987-09-29 | 1997-06-17 | Praxis Biologics, Inc. | Respiratory syncytial virus vaccines |
| WO1992001473A1 (en) * | 1990-07-19 | 1992-02-06 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Improved immunotherapeutic method of preventing or treating viral respiratory tract disease |
| US5344640A (en) * | 1991-10-22 | 1994-09-06 | Mallinckrodt Medical, Inc. | Preparation of apatite particles for medical diagnostic imaging |
| US5824307A (en) * | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
| US5762905A (en) * | 1992-09-16 | 1998-06-09 | The Scripps Research Institute | Human neutralizing monoclonal antibodies to respiratory syncytial virus |
| FR2718452B1 (fr) * | 1994-04-06 | 1996-06-28 | Pf Medicament | Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation. |
| CA2198279A1 (en) * | 1994-08-25 | 1996-02-29 | Johannes Petrus Maria Langedijk | Antigenic peptides derived from the g protein of rsv for type- and subtype-specific diagnosis of respiratory syncytial virus (rsv) infection |
| US5922344A (en) * | 1995-02-10 | 1999-07-13 | Abbott Laboratories | Product for prevention of respiratory virus infection and method of use |
| US5811524A (en) * | 1995-06-07 | 1998-09-22 | Idec Pharmaceuticals Corporation | Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof |
| US20020141990A1 (en) * | 1996-11-01 | 2002-10-03 | Smithkline Beecham Corporation | Anti-RSV human monoclonal antibodies |
| US6699478B1 (en) * | 1997-09-19 | 2004-03-02 | Wyeth Holdings Corporation | Enhanced immune response to attachment (G) protein of Respiratory Syncytial Virus |
| US6656467B2 (en) * | 2000-01-27 | 2003-12-02 | Medimmune, Inc. | Ultra high affinity neutralizing antibodies |
| EP2341074A1 (en) * | 2000-03-01 | 2011-07-06 | MedImmune, LLC | Antibodies binding to the f protein of a respiratory syncytial virus (rsv) |
| US20050175986A1 (en) * | 2000-05-09 | 2005-08-11 | Smit Kline Beecham Corporation | Human monoclonal antibody |
| ATE412666T1 (de) * | 2000-10-18 | 2008-11-15 | Us Gov Health & Human Serv | Zusammensetzungen und verfahren zur modulierung von rsv-infektionen und -immunität |
| US6818216B2 (en) * | 2000-11-28 | 2004-11-16 | Medimmune, Inc. | Anti-RSV antibodies |
| CA2494485A1 (en) * | 2002-07-25 | 2004-02-05 | Medimmune, Inc. | Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies |
| CA2512647C (en) * | 2003-01-07 | 2013-10-08 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
| US20060275766A1 (en) * | 2003-01-07 | 2006-12-07 | Haurum John S | Method for manufacturing recombinant polyclonal proteins |
| US6821450B2 (en) * | 2003-01-21 | 2004-11-23 | Hewlett-Packard Development Company, L.P. | Substrate and method of forming substrate for fluid ejection device |
| JP4783726B2 (ja) * | 2003-03-28 | 2011-09-28 | メディミューン，エルエルシー | 呼吸器合胞体ウイルスサブグループｂ株９３２０に関連する組成物および方法 |
| US7070786B2 (en) * | 2003-06-06 | 2006-07-04 | Centocor, Inc. | RSV proteins, antibodies, compositions, methods and uses |
| TWI333977B (en) * | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| EP1793850A4 (en) * | 2004-09-21 | 2010-06-30 | Medimmune Inc | ANTIBODIES TO THE METHOD AND METHOD FOR THE PRODUCTION OF VACCINES AGAINST THE RESPIRATORY SYNCYTIAL VIRUS |
| JP2009518320A (ja) * | 2005-12-05 | 2009-05-07 | シュムフォウエン アクティーゼルスカブ | 抗オルトポックスウイルス組換えポリクローナル抗体 |
| CN101679513A (zh) * | 2007-03-06 | 2010-03-24 | 西福根有限公司 | 用于治疗呼吸道合胞病毒感染的重组抗体 |
| WO2009048769A2 (en) * | 2007-10-10 | 2009-04-16 | Kirin Pharma Kabushiki Kaisha | Vaccinia virus h3l and b5r specific monoclonal antibodies and methods of making and using same |
-
2007
- 2007-03-06 KR KR1020087024416A patent/KR20080113223A/ko not_active Withdrawn
- 2007-03-06 WO PCT/DK2007/000113 patent/WO2007101441A1/en not_active Ceased
- 2007-03-06 CN CNA2007800077783A patent/CN101395182A/zh active Pending
- 2007-03-06 JP JP2008557594A patent/JP2009528828A/ja not_active Withdrawn
- 2007-03-06 AU AU2007222798A patent/AU2007222798A1/en not_active Abandoned
- 2007-03-06 EP EP07711256A patent/EP2004686A1/en not_active Withdrawn
- 2007-03-06 BR BRPI0708636-9A patent/BRPI0708636A2/pt not_active IP Right Cessation
- 2007-03-06 US US11/792,927 patent/US20100040606A1/en not_active Abandoned
- 2007-03-06 CA CA002638833A patent/CA2638833A1/en not_active Abandoned
- 2007-03-06 MX MX2008011280A patent/MX2008011280A/es not_active Application Discontinuation
-
2008
- 2008-07-22 ZA ZA200806362A patent/ZA200806362B/xx unknown
- 2008-08-12 IL IL193386A patent/IL193386A0/en unknown
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