BRPI0708636A2 - anticorpo policlonal recombinante para tratamento de infecções por vìrus sinciciais respiratórios - Google Patents
anticorpo policlonal recombinante para tratamento de infecções por vìrus sinciciais respiratórios Download PDFInfo
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- BRPI0708636A2 BRPI0708636A2 BRPI0708636-9A BRPI0708636A BRPI0708636A2 BR PI0708636 A2 BRPI0708636 A2 BR PI0708636A2 BR PI0708636 A BRPI0708636 A BR PI0708636A BR PI0708636 A2 BRPI0708636 A2 BR PI0708636A2
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- antibody
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Classifications
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- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
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- Organic Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
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| DKPA200600324 | 2006-03-06 | ||
| DKPA200600324 | 2006-03-06 | ||
| US87471606P | 2006-12-14 | 2006-12-14 | |
| US60/874,716 | 2006-12-14 | ||
| PCT/DK2007/000113 WO2007101441A1 (en) | 2006-03-06 | 2007-03-06 | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
Publications (1)
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| BRPI0708636A2 true BRPI0708636A2 (pt) | 2011-06-07 |
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| BRPI0708636-9A BRPI0708636A2 (pt) | 2006-03-06 | 2007-03-06 | anticorpo policlonal recombinante para tratamento de infecções por vìrus sinciciais respiratórios |
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| US (1) | US20100040606A1 (enExample) |
| EP (1) | EP2004686A1 (enExample) |
| JP (1) | JP2009528828A (enExample) |
| KR (1) | KR20080113223A (enExample) |
| CN (1) | CN101395182A (enExample) |
| AU (1) | AU2007222798A1 (enExample) |
| BR (1) | BRPI0708636A2 (enExample) |
| CA (1) | CA2638833A1 (enExample) |
| IL (1) | IL193386A0 (enExample) |
| MX (1) | MX2008011280A (enExample) |
| WO (1) | WO2007101441A1 (enExample) |
| ZA (1) | ZA200806362B (enExample) |
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| CA2512647C (en) | 2003-01-07 | 2013-10-08 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
| RU2426795C2 (ru) | 2004-07-20 | 2011-08-20 | Симфоген А/С | Способ структурной характеристики рекомбинантного поликлонального белка или поликлональной клеточной линии |
| JP2009518320A (ja) * | 2005-12-05 | 2009-05-07 | シュムフォウエン アクティーゼルスカブ | 抗オルトポックスウイルス組換えポリクローナル抗体 |
| EP2502628B1 (en) * | 2006-06-23 | 2016-12-14 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in cancer |
| PL2132229T3 (pl) | 2007-03-01 | 2016-12-30 | Kompozycje rekombinowanych przeciwciał anty-receptor czynnika wzrostu naskórka | |
| MX2009008908A (es) | 2007-03-01 | 2009-08-28 | Symphogen As | Metodo para clonacion de anticuerpos analogos. |
| CN101679513A (zh) * | 2007-03-06 | 2010-03-24 | 西福根有限公司 | 用于治疗呼吸道合胞病毒感染的重组抗体 |
| NZ581316A (en) | 2007-05-25 | 2012-02-24 | Symphogen As | Method for manufacturing a recombinant polyclonal protein |
| JP2008289483A (ja) * | 2007-05-25 | 2008-12-04 | Symphogen As | 真核生物系において発現可能な形質転換体のスクリーニング |
| CN101821289A (zh) * | 2007-09-07 | 2010-09-01 | 西福根有限公司 | 重组制造抗rsv抗体的方法 |
| WO2009042589A1 (en) * | 2007-09-24 | 2009-04-02 | Vanderbilt University | Monoclonal antibodies to respiratory syncytial virus and uses thereof |
| NZ585589A (en) * | 2007-10-25 | 2012-07-27 | Trellis Bioscience Inc | Anti-rsv g protein antibodies |
| EP2331577B1 (en) | 2008-08-29 | 2017-06-07 | Symphogen A/S | Recombinant anti-epidermal growth factor receptor antibody compositions |
| AU2009301505A1 (en) * | 2008-10-06 | 2010-04-15 | Symphogen A/S | Method for identifying and selecting drug candidates for combinatorial drug products |
| WO2010060186A1 (en) | 2008-11-03 | 2010-06-03 | Alethia Biotherapeutics Inc. | Antibodies that specifically block the biological activity of a tumor antigen |
| GB2483810B (en) | 2008-11-07 | 2012-09-05 | Sequenta Inc | Methods for correlating clonotypes with diseases in a population |
| US8691510B2 (en) * | 2008-11-07 | 2014-04-08 | Sequenta, Inc. | Sequence analysis of complex amplicons |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| PT2387627E (pt) | 2009-01-15 | 2016-06-03 | Adaptive Biotechnologies Corp | Determinação do perfil de imunidade adaptativa e métodos de geração de anticorpos monoclonais |
| JP2012531202A (ja) | 2009-06-25 | 2012-12-10 | フレッド ハチンソン キャンサー リサーチ センター | 適応免疫を測定する方法 |
| CN103977394B (zh) * | 2009-07-17 | 2016-03-09 | 翰林大学校产学协力团 | 包含脂质体包胶的寡核苷酸和表位的免疫刺激性组合物 |
| JP2013507603A (ja) | 2009-10-09 | 2013-03-04 | シムフォゲン・アクティーゼルスカブ | 署名ペプチドおよび質量分析による混合物中の個々の組換えタンパク質の多重定量化 |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| CA3062786C (en) * | 2010-07-09 | 2022-04-19 | Janssen Vaccines & Prevention B.V. | Anti-human respiratory syncytial virus (rsv) antibodies and methods of use |
| EP2625295B1 (en) * | 2010-10-08 | 2019-03-13 | President and Fellows of Harvard College | High-throughput immune sequencing |
| CA2824389A1 (en) * | 2011-01-10 | 2012-07-19 | Emory University | Antibodies directed against influenza |
| DK3173427T3 (da) | 2011-03-31 | 2019-08-05 | Adc Therapeutics Sa | Antistoffer mod nyre-associeret antigen 1 og antigen-bindende fragmenter deraf |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| EP2768982A4 (en) | 2011-10-21 | 2015-06-03 | Adaptive Biotechnologies Corp | QUANTIFICATION OF ADAPTIVE IMMUNOCELL GENOMES IN A COMPLEX MIX OF CELLS |
| AU2012347460B2 (en) | 2011-12-09 | 2017-05-25 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| HRP20190946T1 (hr) | 2012-01-09 | 2019-07-26 | Adc Therapeutics Sa | Sredstva za liječenje trostruko negativnog raka dojke |
| US9546219B2 (en) | 2012-02-08 | 2017-01-17 | North Carolina State University | Treatment of allergic diseases with recombinant antibodies |
| JP6302847B2 (ja) | 2012-03-05 | 2018-03-28 | アダプティヴ バイオテクノロジーズ コーポレーション | 頻度が一致したサブユニットからの、対をなす免疫受容体鎖の決定 |
| ES2711156T3 (es) | 2012-05-08 | 2019-04-30 | Adaptive Biotechnologies Corp | Método para medir y calibrar el sesgo de amplificación en reacciones de PCR multiplexadas |
| PT2887959T (pt) * | 2012-08-23 | 2019-02-01 | Seattle Genetics Inc | Conjugados anticorpo-fármaco (adc) que se ligam a proteínas 158p1d7 |
| EP2904111B1 (en) | 2012-10-01 | 2017-12-06 | Adaptive Biotechnologies Corporation | Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization |
| CA2890427C (en) | 2012-11-06 | 2022-05-31 | Medimmune, Llc | Antibodies to s. aureus surface determinants |
| TWI659968B (zh) * | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒ｆ蛋白質的人類抗體及其使用方法 |
| US10119134B2 (en) | 2013-03-15 | 2018-11-06 | Abvitro Llc | Single cell bar-coding for antibody discovery |
| CN103196731A (zh) * | 2013-04-18 | 2013-07-10 | 王刚平 | 用于鉴别乳腺肌上皮病变的多重染色试剂及其检测方法 |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
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- 2007-03-06 WO PCT/DK2007/000113 patent/WO2007101441A1/en not_active Ceased
- 2007-03-06 CN CNA2007800077783A patent/CN101395182A/zh active Pending
- 2007-03-06 JP JP2008557594A patent/JP2009528828A/ja not_active Withdrawn
- 2007-03-06 AU AU2007222798A patent/AU2007222798A1/en not_active Abandoned
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| US20100040606A1 (en) | 2010-02-18 |
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| ZA200806362B (en) | 2009-05-27 |
| EP2004686A1 (en) | 2008-12-24 |
| JP2009528828A (ja) | 2009-08-13 |
| KR20080113223A (ko) | 2008-12-29 |
| WO2007101441A1 (en) | 2007-09-13 |
| MX2008011280A (es) | 2008-09-12 |
| CN101395182A (zh) | 2009-03-25 |
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