ZA200806362B - Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections - Google Patents
Recombinant polyclonal antibody for treatment of respiratory syncytial virus infectionsInfo
- Publication number
- ZA200806362B ZA200806362B ZA200806362A ZA200806362A ZA200806362B ZA 200806362 B ZA200806362 B ZA 200806362B ZA 200806362 A ZA200806362 A ZA 200806362A ZA 200806362 A ZA200806362 A ZA 200806362A ZA 200806362 B ZA200806362 B ZA 200806362B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- polyclonal antibody
- respiratory syncytial
- syncytial virus
- virus infections
- Prior art date
Links
- 206010061603 Respiratory syncytial virus infection Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200600324 | 2006-03-06 | ||
US87471606P | 2006-12-14 | 2006-12-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200806362B true ZA200806362B (en) | 2009-05-27 |
Family
ID=38230163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200806362A ZA200806362B (en) | 2006-03-06 | 2008-07-22 | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
Country Status (12)
Country | Link |
---|---|
US (1) | US20100040606A1 (xx) |
EP (1) | EP2004686A1 (xx) |
JP (1) | JP2009528828A (xx) |
KR (1) | KR20080113223A (xx) |
CN (1) | CN101395182A (xx) |
AU (1) | AU2007222798A1 (xx) |
BR (1) | BRPI0708636A2 (xx) |
CA (1) | CA2638833A1 (xx) |
IL (1) | IL193386A0 (xx) |
MX (1) | MX2008011280A (xx) |
WO (1) | WO2007101441A1 (xx) |
ZA (1) | ZA200806362B (xx) |
Families Citing this family (66)
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WO2004061104A2 (en) | 2003-01-07 | 2004-07-22 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
ES2332524T3 (es) | 2004-07-20 | 2010-02-08 | Symphogen A/S | Un procedimiento para la caracterizacion de una linea celular policlonal. |
AU2006322445B2 (en) | 2005-12-05 | 2011-05-12 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
JP5564249B2 (ja) * | 2006-06-23 | 2014-07-30 | アレシア・バイオセラピューティクス・インコーポレーテッド | 癌に関与するポリヌクレオチド配列およびポリペプチド配列 |
RU2459868C2 (ru) | 2007-03-01 | 2012-08-27 | Симфоген А/С | Способ клонирования когнатных антител |
KR101676622B1 (ko) | 2007-03-01 | 2016-11-17 | 심포젠 에이/에스 | 재조합 항-표피 성장 인자 수용체 항체 조성물 |
CA2678628A1 (en) * | 2007-03-06 | 2008-09-12 | Symphogen A/S | Recombinant antibodies for treatment of respiratory syncytial virus infections |
JP2008289483A (ja) * | 2007-05-25 | 2008-12-04 | Symphogen As | 真核生物系において発現可能な形質転換体のスクリーニング |
BRPI0812091A2 (pt) | 2007-05-25 | 2014-10-14 | Symphogen As | Método para fabricar uma proteína policlonal recombinante |
WO2009030237A2 (en) * | 2007-09-07 | 2009-03-12 | Symphogen A/S | Methods for recombinant manufacturing of anti-rsv antibodies |
EP2201040A1 (en) | 2007-09-24 | 2010-06-30 | Vanderbilt University | Monoclonal antibodies to respiratory syncytial virus and uses thereof |
US7736648B2 (en) * | 2007-10-25 | 2010-06-15 | Trellis Bioscience, Inc. | Anti-RSV G protein antibodies |
KR101706255B1 (ko) | 2008-08-29 | 2017-02-14 | 심포젠 에이/에스 | 재조합 항-표피 성장 인자 수용체 항체 조성물 |
EP2335068A4 (en) * | 2008-10-06 | 2012-07-25 | Symphogen As | METHOD FOR IDENTIFYING AND SELECTING CANDIDATES MEDICINES FOR COMBINATORIAL DRUG PRODUCTS |
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US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
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GB2497007B (en) * | 2008-11-07 | 2013-08-07 | Sequenta Inc | Methods of monitoring disease conditions by analysis of the full repertoire of the V-D junction or D-J junction sequences of an individual |
US8691510B2 (en) * | 2008-11-07 | 2014-04-08 | Sequenta, Inc. | Sequence analysis of complex amplicons |
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ES2776179T3 (es) * | 2012-11-06 | 2020-07-29 | Medimmune Llc | Anticuerpos dirigidos contra determinantes de la superficie de S. aureus |
TWI659968B (zh) | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒f蛋白質的人類抗體及其使用方法 |
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CN110799211A (zh) * | 2016-09-08 | 2020-02-14 | 美国德州精准药靶有限公司 | 特异性识别丛蛋白-信号素-整合素结构域的抗ron单克隆抗体的药物呈递作用及其在肿瘤治疗中的应用 |
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-
2007
- 2007-03-06 EP EP07711256A patent/EP2004686A1/en not_active Withdrawn
- 2007-03-06 WO PCT/DK2007/000113 patent/WO2007101441A1/en active Application Filing
- 2007-03-06 CA CA002638833A patent/CA2638833A1/en not_active Abandoned
- 2007-03-06 JP JP2008557594A patent/JP2009528828A/ja not_active Withdrawn
- 2007-03-06 US US11/792,927 patent/US20100040606A1/en not_active Abandoned
- 2007-03-06 BR BRPI0708636-9A patent/BRPI0708636A2/pt not_active IP Right Cessation
- 2007-03-06 KR KR1020087024416A patent/KR20080113223A/ko not_active Application Discontinuation
- 2007-03-06 MX MX2008011280A patent/MX2008011280A/es not_active Application Discontinuation
- 2007-03-06 CN CNA2007800077783A patent/CN101395182A/zh active Pending
- 2007-03-06 AU AU2007222798A patent/AU2007222798A1/en not_active Abandoned
-
2008
- 2008-07-22 ZA ZA200806362A patent/ZA200806362B/xx unknown
- 2008-08-12 IL IL193386A patent/IL193386A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL193386A0 (en) | 2011-08-01 |
US20100040606A1 (en) | 2010-02-18 |
KR20080113223A (ko) | 2008-12-29 |
BRPI0708636A2 (pt) | 2011-06-07 |
CA2638833A1 (en) | 2007-09-13 |
EP2004686A1 (en) | 2008-12-24 |
CN101395182A (zh) | 2009-03-25 |
MX2008011280A (es) | 2008-09-12 |
JP2009528828A (ja) | 2009-08-13 |
WO2007101441A1 (en) | 2007-09-13 |
AU2007222798A1 (en) | 2007-09-13 |
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