HK1189884A1 - 用於治療呼吸道合胞病毒感染的化合物 - Google Patents

用於治療呼吸道合胞病毒感染的化合物

Info

Publication number
HK1189884A1
HK1189884A1 HK14102907.2A HK14102907A HK1189884A1 HK 1189884 A1 HK1189884 A1 HK 1189884A1 HK 14102907 A HK14102907 A HK 14102907A HK 1189884 A1 HK1189884 A1 HK 1189884A1
Authority
HK
Hong Kong
Prior art keywords
compounds
respiratory syncytial
syncytial virus
virus infections
treating respiratory
Prior art date
Application number
HK14102907.2A
Other languages
English (en)
Inventor
Penelope Anne Mayes
Jeffrey Peter Mitchell
Alistair George Draffan
Gary Robert William Pitt
Kelly Helen Anderson
Chin Yu Lim
Original Assignee
Biota Scient Management
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2010905234A external-priority patent/AU2010905234A0/en
Application filed by Biota Scient Management filed Critical Biota Scient Management
Publication of HK1189884A1 publication Critical patent/HK1189884A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK14102907.2A 2010-11-26 2014-04-04 用於治療呼吸道合胞病毒感染的化合物 HK1189884A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41734710P 2010-11-26 2010-11-26
AU2010905234A AU2010905234A0 (en) 2010-11-26 Compounds for treating respiratory syncytial virus infections
PCT/AU2011/001509 WO2012068622A1 (en) 2010-11-26 2011-11-23 Compounds for treating respiratory syncytial virus infections

Publications (1)

Publication Number Publication Date
HK1189884A1 true HK1189884A1 (zh) 2014-06-20

Family

ID=46127038

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14102907.2A HK1189884A1 (zh) 2010-11-26 2014-04-04 用於治療呼吸道合胞病毒感染的化合物

Country Status (18)

Country Link
US (1) US8796303B2 (zh)
EP (1) EP2643323B1 (zh)
JP (1) JP5870112B2 (zh)
KR (1) KR20130116289A (zh)
CN (1) CN103282366B (zh)
AR (1) AR084011A1 (zh)
AU (1) AU2011334602B2 (zh)
BR (1) BR112013012998A2 (zh)
CA (1) CA2818938A1 (zh)
EA (1) EA024375B1 (zh)
HK (1) HK1189884A1 (zh)
IL (1) IL226579A (zh)
MX (1) MX340190B (zh)
NZ (1) NZ611808A (zh)
SG (1) SG190842A1 (zh)
TW (1) TWI515193B (zh)
WO (1) WO2012068622A1 (zh)
ZA (1) ZA201304117B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2739629B1 (en) 2011-08-05 2016-10-05 Biota Scientific Management Pty Ltd Compounds for treating respiratory syncytial virus infections
UA123854C2 (uk) 2013-08-21 2021-06-16 Аліос Біофарма, Інк. Противірусні сполуки
MA41614A (fr) 2015-02-25 2018-01-02 Alios Biopharma Inc Composés antiviraux
HUE060259T2 (hu) 2015-07-22 2023-02-28 Enanta Pharm Inc Benzodiazepin származékok mint RSV-gátlók
CN108699077B (zh) 2016-01-15 2021-03-02 英安塔制药有限公司 作为rsv抑制剂的杂环化合物
CA3065368A1 (en) 2017-02-16 2018-08-23 Enanta Pharmaceuticals, Inc. Processes for the preparation of benzodiazepine derivatives
US11091501B2 (en) 2017-06-30 2021-08-17 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
BR112020006334A2 (pt) 2017-09-29 2020-09-24 Enanta Pharmaceuticals, Inc. combinação de agentes farmacêuticos como inibidores de rsv
WO2019094903A1 (en) 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives
KR20210138684A (ko) 2019-03-18 2021-11-19 이난타 파마슈티칼스, 인코포레이티드 Rsv 억제제로서의 벤조디아제핀 유도체
AU2020357452A1 (en) 2019-10-04 2022-05-12 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en) 2020-07-07 2022-12-27 Enanta Pharmaceuticals, Inc. Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
WO2022086840A1 (en) 2020-10-19 2022-04-28 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents
BR112023016970A2 (pt) 2021-02-26 2023-10-10 Enanta Pharm Inc Compostos heterocíclicos antivirais

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137586C (zh) 1963-04-11
US3507863A (en) 1963-12-18 1970-04-21 Sandoz Ag Isoindolones and method for preparing same
NL126596C (zh) 1964-02-11
NL129866C (zh) 1965-09-21
CH480350A (de) 1965-09-21 1969-10-31 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
US3379733A (en) 1965-12-07 1968-04-23 Sandoz Ag N-(omega-aminoalkyl)isoindoles and method for preparing same
CH481124A (de) 1966-09-21 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
FR1580180A (zh) 1967-03-14 1969-09-05
CH482697A (de) 1967-03-17 1969-12-15 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
US3935218A (en) 1968-09-05 1976-01-27 American Home Products Corporation Imidazolinyl phenyl carbonyl compounds acid addition salts and related compounds
US3885037A (en) 1968-09-05 1975-05-20 American Home Prod Method of producing anorexia using imidazolinyl phenyl carbonyl compounds, their acid addition salts and related compounds
US3657221A (en) 1969-02-19 1972-04-18 American Home Prod Process for preparing 9b-substituted-1 - sulfonyl - 1 2 3 9b - tetrahydro-5h-imidazo(2 1-a)isoindol-5-ones
GB1322339A (en) 1970-03-10 1973-07-04 American Home Prod Imidazoline derivatives
US3770766A (en) 1970-03-10 1973-11-06 American Home Prod 2-(2-amino-2,2-dialkylamino-3-hydroxy-3-phenyl-1h-benz(f)isoindole-1-ones
US3624101A (en) 1970-03-10 1971-11-30 American Home Prod 2,3-DIHYDRO-5-ARYL-5H-BENZ{8 f{9 IMIDAZO{8 2,1-a{9 ISOINDOL-5-OLS
US3966955A (en) 1974-08-07 1976-06-29 American Home Products Corporation Anti-ulcer therapy
US4056536A (en) 1976-06-29 1977-11-01 Merck & Co., Inc. Pyrrolo[2,1-b][3]benzazepines
US4701208A (en) 1983-08-02 1987-10-20 American Cyanamid Company Dihydroimidazopyrrolopyridine, quinoline, thieno- and furo[2,3-b]pyridine, dihydrothieno- and furo[2,3-b]-pyridine, thieno- and furo[3,2-b]pyridine and dihydrothieno- and furo[3,2-b]pyridine herbicides and method for preparation thereof
DE3520390A1 (de) 1984-07-07 1986-02-06 Bayer Ag, 5090 Leverkusen Imidazo-pyrrolo-pyridin-derivate
EP0183993A3 (de) 1984-11-16 1987-12-09 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft 2H-Imidazo[1',2':1,2]pyrrolo[3,4-b]pyridine und deren Verwendung als Unkrautbekämpfungsmittel
EP0195745B1 (de) 1985-03-12 1990-09-12 Ciba-Geigy Ag Heterocyclisch kondensierte Pyridin-Verbindungen als Herbizide
DE3534948A1 (de) 1985-10-01 1987-04-09 Bayer Ag Fungizide und wachstumsregulatorische mittel
US4717414A (en) 1986-08-08 1988-01-05 Ppg Industries, Inc. Herbicidally active imidazopyrrolo-pyridine (or benzene) derivatives
DE3634952A1 (de) 1986-10-14 1988-04-21 Bayer Ag Imidazo-pyrrolo-pyridin-derivate
EP0475908A1 (de) 1990-09-14 1992-03-18 Ciba-Geigy Ag Chromogene Lactamverbindungen und ihre Herstellung und Verwendung
DE4103177A1 (de) 1991-02-02 1992-08-06 Boehringer Mannheim Gmbh Thiazolo-(2,3-a)isoindol-derivate und diese enthaltende arzneimittel
JPH06505017A (ja) 1991-02-28 1994-06-09 ベーリンガー　マンハイム　ゲーエムベーハー 三環式イソインドリノンの抗ウイルス医薬としての使用、ならびに新規な光学活性イソインドリノン
DE4108395A1 (de) 1991-03-15 1993-01-28 Boehringer Mannheim Gmbh Verwendung von oxazolo-(2,3-a)isoindol-und imidazo(2,1-a)-isoindol-derivaten als antivirale arzneimittel sowie neue oxazolo(2,3-a)isoindol-derivaten
DE4129779A1 (de) 1991-09-07 1993-03-11 Boehringer Mannheim Gmbh Neue tricyclische thiazol- und oxazol-derivate und diese enthaltende arzneimittel
ATE316089T1 (de) 1999-08-25 2006-02-15 Banyu Pharma Co Ltd Isoindolderivate
US6489338B2 (en) 2000-06-13 2002-12-03 Bristol-Myers Squibb Company Imidazopyridine and imidazopyrimidine antiviral agents
US6506738B1 (en) 2000-09-27 2003-01-14 Bristol-Myers Squibb Company Benzimidazolone antiviral agents
AU2002223275A1 (en) 2000-11-22 2002-06-03 Biota Scientific Management Pty Ltd A method of expression and agents identified thereby
WO2002066479A1 (fr) 2001-02-23 2002-08-29 Banyu Pharmaceutical Co.,Ltd. Derives de l'isoindole
AUPR878401A0 (en) 2001-11-09 2001-12-06 Biota Holdings Ltd Methods for identifying or screening anti-viral agents
RU2422444C2 (ru) * 2003-12-24 2011-06-27 Байота Сайентифик Менеджмент Пти Лтд Полициклические средства для лечения респираторно-синцитиальных вирусных инфекций
DK2465580T3 (en) 2005-04-28 2014-03-10 Viiv Healthcare Co POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVES WITH HIV INTEGRASE INHIBITIVE ACTIVITY
TWI423972B (zh) 2006-09-28 2014-01-21 Biota Scient Management 治療呼吸系融合細胞病毒感染之多環劑
US20100081713A1 (en) * 2008-03-19 2010-04-01 CombinatoRx, (Singapore) Pte. Ltd. Compositions and methods for treating viral infections
TWI508968B (zh) * 2010-02-08 2015-11-21 Biota Scient Management 用於治療呼吸道融合性病毒感染的化合物

Also Published As

Publication number Publication date
JP5870112B2 (ja) 2016-02-24
CA2818938A1 (en) 2012-05-31
IL226579A (en) 2016-10-31
JP2013543873A (ja) 2013-12-09
MX340190B (es) 2016-06-28
EP2643323B1 (en) 2015-10-14
AU2011334602A1 (en) 2013-07-11
SG190842A1 (en) 2013-07-31
EP2643323A1 (en) 2013-10-02
US8796303B2 (en) 2014-08-05
BR112013012998A2 (pt) 2016-09-13
AR084011A1 (es) 2013-04-17
NZ611808A (en) 2015-05-29
TWI515193B (zh) 2016-01-01
KR20130116289A (ko) 2013-10-23
CN103282366B (zh) 2016-12-21
WO2012068622A1 (en) 2012-05-31
AU2011334602B2 (en) 2015-11-26
ZA201304117B (en) 2014-02-26
US20120135998A1 (en) 2012-05-31
MX2013005904A (es) 2013-06-18
CN103282366A (zh) 2013-09-04
EP2643323A4 (en) 2013-10-09
TW201305163A (zh) 2013-02-01
EA201300604A1 (ru) 2013-10-30
EA024375B1 (ru) 2016-09-30

Similar Documents

Publication Publication Date Title
HK1189884A1 (zh) 用於治療呼吸道合胞病毒感染的化合物
HK1247616A1 (zh) 苯並咪唑呼吸道合胞病毒抑制劑
HK1221657A1 (zh) 用於治療副黏病毒科病毒感染的方法和化合物
HK1196131A1 (zh) 用於治療或預防呼吸道合胞病毒疾病的化合物
HK1211589A1 (zh) 用於治療副粘病毒病毒性感染的化合物
EP2776107A4 (en) EXCHANGER ASSEMBLY FOR THE TREATMENT OF RESPIRATORY WAYS
IL226348A0 (en) An oligosaccharide compound for the treatment of urinary tract infections
SG10201607576PA (en) Devices for treating nasal airways
GB0816679D0 (en) Compounds for treating viral infections
IL221320A0 (en) Compounds for treating respiratory syncytial virus infections
HK1197058A1 (zh) 用於治療或預防呼吸道合胞病毒疾病的化合物
AU339729S (en) Respiratory mask
GB201203180D0 (en) Compounds for treating parvovirus infection
EP2536282A4 (en) METHOD FOR THE TREATMENT OF INFECTIONS
EP2739629A4 (en) COMPOUNDS FOR THE TREATMENT OF SYNCYTIAL RESPIRATORY VIRUS INFECTIONS
ZA201207696B (en) Compound for treatment of respiratory condition or disease
EP2563353A4 (en) COMPOUNDS FOR ANTIFUNGAL TREATMENT
AU2010905234A0 (en) Compounds for treating respiratory syncytial virus infections
AU2010900494A0 (en) Compound for treating respiratory syncytial virus infections
ZA201400442B (en) Compounds for the treatment and prophylaxis of respiratory syncytial virus disease
EP2589595A4 (en) MEANS FOR THE TREATMENT OF HCV INFECTIONS
GB201101898D0 (en) Air treatment system

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20191126