EA201300604A1 - Соединения, предназначенные для лечения респираторно-синцитиальных вирусных инфекций - Google Patents

Соединения, предназначенные для лечения респираторно-синцитиальных вирусных инфекций

Info

Publication number
EA201300604A1
EA201300604A1 EA201300604A EA201300604A EA201300604A1 EA 201300604 A1 EA201300604 A1 EA 201300604A1 EA 201300604 A EA201300604 A EA 201300604A EA 201300604 A EA201300604 A EA 201300604A EA 201300604 A1 EA201300604 A1 EA 201300604A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
viral infections
respiratory
compounds intended
compounds
Prior art date
Application number
EA201300604A
Other languages
English (en)
Other versions
EA024375B1 (ru
Inventor
Пенелопе Анна Мэйес
Джеффри Питер Митчелл
Алистер Джордж Дрэффан
Гэри Роберт Уильям Питт
Келли Хелен Андерсон
Чин Ю Лим
Original Assignee
Байота Сайентифик Менеджмент Пти Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2010905234A external-priority patent/AU2010905234A0/en
Application filed by Байота Сайентифик Менеджмент Пти Лтд. filed Critical Байота Сайентифик Менеджмент Пти Лтд.
Publication of EA201300604A1 publication Critical patent/EA201300604A1/ru
Publication of EA024375B1 publication Critical patent/EA024375B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Abstract

Настоящее изобретение относится к соединениям формулы (I), его рацематам, изомерам и/или солям, пригодным при лечении вирусных инфекций, в частности инфекций, вызванных респираторным синцитиальным вирусом (RSV). Настоящее изобретение также относится к способам получения данных соединений.
EA201300604A 2010-11-26 2011-11-23 Соединения, предназначенные для лечения респираторно-синцитиальных вирусных инфекций EA024375B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41734710P 2010-11-26 2010-11-26
AU2010905234A AU2010905234A0 (en) 2010-11-26 Compounds for treating respiratory syncytial virus infections
PCT/AU2011/001509 WO2012068622A1 (en) 2010-11-26 2011-11-23 Compounds for treating respiratory syncytial virus infections

Publications (2)

Publication Number Publication Date
EA201300604A1 true EA201300604A1 (ru) 2013-10-30
EA024375B1 EA024375B1 (ru) 2016-09-30

Family

ID=46127038

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201300604A EA024375B1 (ru) 2010-11-26 2011-11-23 Соединения, предназначенные для лечения респираторно-синцитиальных вирусных инфекций

Country Status (18)

Country Link
US (1) US8796303B2 (ru)
EP (1) EP2643323B1 (ru)
JP (1) JP5870112B2 (ru)
KR (1) KR20130116289A (ru)
CN (1) CN103282366B (ru)
AR (1) AR084011A1 (ru)
AU (1) AU2011334602B2 (ru)
BR (1) BR112013012998A2 (ru)
CA (1) CA2818938A1 (ru)
EA (1) EA024375B1 (ru)
HK (1) HK1189884A1 (ru)
IL (1) IL226579A (ru)
MX (1) MX340190B (ru)
NZ (1) NZ611808A (ru)
SG (1) SG190842A1 (ru)
TW (1) TWI515193B (ru)
WO (1) WO2012068622A1 (ru)
ZA (1) ZA201304117B (ru)

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UA123854C2 (uk) 2013-08-21 2021-06-16 Аліос Біофарма, Інк. Противірусні сполуки
MA41614A (fr) 2015-02-25 2018-01-02 Alios Biopharma Inc Composés antiviraux
KR20180041142A (ko) 2015-07-22 2018-04-23 이난타 파마슈티칼스, 인코포레이티드 Rsv 저해제로서의 벤조다이아제핀 유도체
CN108699077B (zh) 2016-01-15 2021-03-02 英安塔制药有限公司 作为rsv抑制剂的杂环化合物
IL268737B2 (en) 2017-02-16 2024-02-01 Enanta Pharm Inc Processes for the preparation of benzodiapine derivatives
WO2019006295A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
WO2019067864A1 (en) 2017-09-29 2019-04-04 Enanta Pharmaceuticals, Inc. PHARMACEUTICAL AGENTS IN COMBINATION AS INHIBITORS OF RSV
IL274534B (en) 2017-11-13 2022-07-01 Enanta Pharm Inc Processes for the separation of 2-one benzodiazepines and 2-one benzodiazepine derivatives
SG11202110137VA (en) 2019-03-18 2021-10-28 Enanta Pharm Inc Benzodiazepine derivatives as rsv inhibitors
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
EP4037688A4 (en) 2019-10-04 2023-09-06 Enanta Pharmaceuticals, Inc. ANTIVIRAL HETEROCYCLIC COMPOUNDS
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en) 2020-07-07 2022-12-27 Enanta Pharmaceuticals, Inc. Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
US11945824B2 (en) 2020-10-19 2024-04-02 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents
CA3173354A1 (en) 2021-02-26 2022-09-01 Adam SZYMANIAK Antiviral heterocyclic compounds

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Also Published As

Publication number Publication date
US8796303B2 (en) 2014-08-05
CA2818938A1 (en) 2012-05-31
EP2643323B1 (en) 2015-10-14
US20120135998A1 (en) 2012-05-31
JP2013543873A (ja) 2013-12-09
JP5870112B2 (ja) 2016-02-24
WO2012068622A1 (en) 2012-05-31
HK1189884A1 (zh) 2014-06-20
MX2013005904A (es) 2013-06-18
ZA201304117B (en) 2014-02-26
CN103282366B (zh) 2016-12-21
NZ611808A (en) 2015-05-29
IL226579A (en) 2016-10-31
TWI515193B (zh) 2016-01-01
AU2011334602B2 (en) 2015-11-26
EA024375B1 (ru) 2016-09-30
EP2643323A1 (en) 2013-10-02
MX340190B (es) 2016-06-28
AU2011334602A1 (en) 2013-07-11
KR20130116289A (ko) 2013-10-23
EP2643323A4 (en) 2013-10-09
TW201305163A (zh) 2013-02-01
SG190842A1 (en) 2013-07-31
BR112013012998A2 (pt) 2016-09-13
CN103282366A (zh) 2013-09-04
AR084011A1 (es) 2013-04-17

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU