JP2009527509A5 - - Google Patents
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- Publication number
- JP2009527509A5 JP2009527509A5 JP2008555597A JP2008555597A JP2009527509A5 JP 2009527509 A5 JP2009527509 A5 JP 2009527509A5 JP 2008555597 A JP2008555597 A JP 2008555597A JP 2008555597 A JP2008555597 A JP 2008555597A JP 2009527509 A5 JP2009527509 A5 JP 2009527509A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- tetrazol
- biphenyl
- imidazole
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(c1c2cccc1)OC2=O Chemical compound *C(c1c2cccc1)OC2=O 0.000 description 4
- DVTFHPFIWRQJLP-UHFFFAOYSA-N CC(OCCl)OC(C)(C)C Chemical compound CC(OCCl)OC(C)(C)C DVTFHPFIWRQJLP-UHFFFAOYSA-N 0.000 description 1
- OPTCHSMAUQAOEX-UHFFFAOYSA-N CCC(O1)=C(C)OC1=O Chemical compound CCC(O1)=C(C)OC1=O OPTCHSMAUQAOEX-UHFFFAOYSA-N 0.000 description 1
- UXABWSFGZWKARE-UHFFFAOYSA-N CCCCC(C(Cc(cc1)ccc1-c(cccc1)c1-c1nnn[nH]1)CC1)=NC(Cl)=C1C(O)=O Chemical compound CCCCC(C(Cc(cc1)ccc1-c(cccc1)c1-c1nnn[nH]1)CC1)=NC(Cl)=C1C(O)=O UXABWSFGZWKARE-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610023991.0 | 2006-02-20 | ||
| CNA2006100239910A CN101024643A (zh) | 2006-02-20 | 2006-02-20 | 咪唑－5－羧酸类衍生物、制备方法及其应用 |
| PCT/CN2006/001914 WO2007095789A1 (en) | 2006-02-20 | 2006-07-31 | Imidazol-5-carboxylic acid derivatives, preparation methods and use therrof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009527509A JP2009527509A (ja) | 2009-07-30 |
| JP2009527509A5 true JP2009527509A5 (https=) | 2009-09-24 |
| JP5250760B2 JP5250760B2 (ja) | 2013-07-31 |
Family
ID=38436915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008555597A Expired - Fee Related JP5250760B2 (ja) | 2006-02-20 | 2006-07-31 | イミダゾール−５−カルボン酸系誘導体、製造方法及びその応用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | USRE44873E1 (https=) |
| EP (1) | EP1988090B1 (https=) |
| JP (1) | JP5250760B2 (https=) |
| KR (1) | KR101179110B1 (https=) |
| CN (2) | CN101024643A (https=) |
| AU (1) | AU2006338796B2 (https=) |
| CA (1) | CA2643005C (https=) |
| DK (1) | DK1988090T3 (https=) |
| ES (1) | ES2424154T3 (https=) |
| PL (1) | PL1988090T3 (https=) |
| PT (1) | PT1988090E (https=) |
| WO (1) | WO2007095789A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101024643A (zh) | 2006-02-20 | 2007-08-29 | 上海艾力斯医药科技有限公司 | 咪唑－5－羧酸类衍生物、制备方法及其应用 |
| ATE525371T1 (de) * | 2006-12-06 | 2011-10-15 | Shanghai Allist Pharmaceutical Inc | Salze von imidazol-5-carbonsäure-derivaten, herstellungsverfahren und verwendung davon |
| CN101214242A (zh) | 2007-01-05 | 2008-07-09 | 上海艾力斯医药科技有限公司 | 新的药用组合物 |
| CN101317842A (zh) * | 2007-06-07 | 2008-12-10 | 上海艾力斯医药科技有限公司 | 一种咪唑-5-羧酸衍生物的治疗用途 |
| CN101407511B (zh) * | 2007-10-11 | 2013-01-09 | 上海艾力斯生物医药有限公司 | 一种结晶型的咪唑-5-羧酸衍生物 |
| AU2009246670A1 (en) * | 2008-05-15 | 2009-11-19 | Merck Sharp & Dohme Corp. | Angiotensin II receptor antagonists |
| CN101596189A (zh) * | 2008-06-05 | 2009-12-09 | 上海艾力斯生物医药有限公司 | 含有咪唑-5-羧酸类衍生物的药用组合物 |
| EP2365966A4 (en) * | 2008-12-12 | 2012-05-09 | Pharmacostech Co Ltd | PROCESS FOR REMOVING THE TRIPHENYLMETHANE GRIP |
| KR101213467B1 (ko) * | 2010-04-30 | 2012-12-20 | 진양제약주식회사 | 로자탄 대사체 이엑스피-3174 이수화물의 신규한 제조 방법 |
| CN103012377A (zh) * | 2011-09-27 | 2013-04-03 | 江苏艾力斯生物医药有限公司 | 一种咪唑-5-羧酸酯的重结晶方法 |
| CN102558064B (zh) * | 2012-01-29 | 2014-04-16 | 安润医药科技（苏州）有限公司 | 抗高血压化合物及其制备方法和应用，以及其在药学上可接受的盐 |
| CN109320501B (zh) * | 2013-11-01 | 2021-06-01 | 深圳信立泰药业股份有限公司 | 阿利沙坦酯无定形及其制备方法及含所述无定形的药物组合物 |
| CN103965171A (zh) * | 2014-04-30 | 2014-08-06 | 上海艾力斯医药科技有限公司 | 一种阿利沙坦酯的制备方法 |
| CN106188012B (zh) | 2014-06-20 | 2018-11-30 | 深圳信立泰药业股份有限公司 | 一种阿利沙坦酯结晶及其制备方法及含有该结晶的药物组合物 |
| CN105218527B (zh) * | 2015-10-10 | 2018-04-24 | 江苏宝众宝达药业有限公司 | 一种exp-3174的制备方法 |
| RS66618B1 (sr) | 2016-01-20 | 2025-04-30 | Shenzhen Salubris Pharm Co Ltd | Kompozit metabolita antagonista receptora angiotenzina ii i inhibitora nep i postupak za njegovu pripremu |
| CN119371408B (zh) * | 2024-12-27 | 2025-04-22 | 安徽艾立德制药有限公司 | 一种无定形的阿利沙坦酯及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5138069A (en) | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
| CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| US5196444A (en) | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
| US5616599A (en) | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
| AT398202B (de) * | 1991-10-04 | 1994-10-25 | Chem Pharm Forsch Gmbh | Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung |
| PT573218E (pt) * | 1992-06-02 | 2001-06-29 | Sankyo Co | 4-carbonilimidazoles como antagonistas de angiotensina ii e sua utilizacao terapeutica |
| JPH083162A (ja) * | 1994-04-19 | 1996-01-09 | Tanabe Seiyaku Co Ltd | イミダゾピリジン誘導体及びその製法 |
| DK0831910T3 (da) * | 1995-06-07 | 2002-05-21 | Searle & Co | Kombinationsterapi med epoxy-steroid aldosteronantagonist og angiotensin II-receptorantagonist til behandling af kongestivt hjertesvigt |
| PL1653950T3 (pl) | 2003-07-31 | 2008-08-29 | Nicox Sa | Pochodne nitrooksylowe losartanu, walsartanu, kandesartanu, telmisartanu, eprosartanu i olmesartanu jako antagonisty receptorów angiotensyny II do leczenia chorób sercowo-naczyniowych |
| CA2536975A1 (en) | 2003-08-28 | 2005-03-17 | Nitromed, Inc. | Nitrosated and nitrosylated diuretic compounds, compositions and methods of use |
| ES2334386T3 (es) | 2005-04-22 | 2010-03-09 | Daiichi Sankyo Company, Limited | Producto farmaceutico para la prevencion o el tratamiento de una enfermedad metabolica osea. |
| CN101024643A (zh) | 2006-02-20 | 2007-08-29 | 上海艾力斯医药科技有限公司 | 咪唑－5－羧酸类衍生物、制备方法及其应用 |
| ATE525371T1 (de) | 2006-12-06 | 2011-10-15 | Shanghai Allist Pharmaceutical Inc | Salze von imidazol-5-carbonsäure-derivaten, herstellungsverfahren und verwendung davon |
| CN101214242A (zh) | 2007-01-05 | 2008-07-09 | 上海艾力斯医药科技有限公司 | 新的药用组合物 |
| CN101317842A (zh) | 2007-06-07 | 2008-12-10 | 上海艾力斯医药科技有限公司 | 一种咪唑-5-羧酸衍生物的治疗用途 |
| CN101407511B (zh) | 2007-10-11 | 2013-01-09 | 上海艾力斯生物医药有限公司 | 一种结晶型的咪唑-5-羧酸衍生物 |
-
2006
- 2006-02-20 CN CNA2006100239910A patent/CN101024643A/zh active Pending
- 2006-07-31 KR KR1020087022811A patent/KR101179110B1/ko not_active Expired - Fee Related
- 2006-07-31 US US13/727,587 patent/USRE44873E1/en active Active
- 2006-07-31 CN CNB2006800003978A patent/CN100506818C/zh active Active
- 2006-07-31 ES ES06775249T patent/ES2424154T3/es active Active
- 2006-07-31 US US11/576,094 patent/US7858651B2/en active Active
- 2006-07-31 WO PCT/CN2006/001914 patent/WO2007095789A1/zh not_active Ceased
- 2006-07-31 AU AU2006338796A patent/AU2006338796B2/en not_active Ceased
- 2006-07-31 PT PT67752493T patent/PT1988090E/pt unknown
- 2006-07-31 JP JP2008555597A patent/JP5250760B2/ja not_active Expired - Fee Related
- 2006-07-31 CA CA2643005A patent/CA2643005C/en not_active Expired - Fee Related
- 2006-07-31 DK DK06775249.3T patent/DK1988090T3/da active
- 2006-07-31 EP EP06775249.3A patent/EP1988090B1/en not_active Not-in-force
- 2006-07-31 PL PL06775249T patent/PL1988090T3/pl unknown
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