JP2009525277A - 軟組織石灰化の回復、予防、遅延または安定化方法 - Google Patents

軟組織石灰化の回復、予防、遅延または安定化方法 Download PDF

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JP2009525277A
JP2009525277A JP2008552435A JP2008552435A JP2009525277A JP 2009525277 A JP2009525277 A JP 2009525277A JP 2008552435 A JP2008552435 A JP 2008552435A JP 2008552435 A JP2008552435 A JP 2008552435A JP 2009525277 A JP2009525277 A JP 2009525277A
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ferric
organic
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soft tissue
organic compound
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チャン,キース
タウン,ウィンストン
チャン,ショウ,シャン
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グロボアジア エルエルシー
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Priority claimed from PCT/US2006/032385 external-priority patent/WO2007022435A2/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/295Iron group metal compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2008552435A 2006-01-30 2007-01-26 軟組織石灰化の回復、予防、遅延または安定化方法 Pending JP2009525277A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76325306P 2006-01-30 2006-01-30
PCT/US2006/032385 WO2007022435A2 (en) 2005-08-18 2006-08-18 Pharmaceutical-grade ferric organic compounds, uses thereof and methods of making same
PCT/US2007/002157 WO2007089577A2 (en) 2006-01-30 2007-01-26 Method of reversing, preventing, delaying or stabilizing soft tissue calcification

Related Child Applications (1)

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JP2013142389A Division JP6154226B2 (ja) 2006-01-30 2013-07-08 軟組織石灰化の回復、予防、遅延または安定化方法

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JP2009525277A true JP2009525277A (ja) 2009-07-09

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JP2008552435A Pending JP2009525277A (ja) 2006-01-30 2007-01-26 軟組織石灰化の回復、予防、遅延または安定化方法
JP2008552431A Pending JP2009525276A (ja) 2006-01-30 2007-01-26 慢性腎疾患の治療法
JP2013142389A Active JP6154226B2 (ja) 2006-01-30 2013-07-08 軟組織石灰化の回復、予防、遅延または安定化方法
JP2013142517A Pending JP2013227333A (ja) 2006-01-30 2013-07-08 慢性腎疾患の治療法
JP2014157464A Active JP6368186B2 (ja) 2006-01-30 2014-08-01 慢性腎疾患の治療法
JP2015180311A Active JP6632842B2 (ja) 2006-01-30 2015-09-14 慢性腎疾患の治療法
JP2016176150A Pending JP2017036289A (ja) 2006-01-30 2016-09-09 慢性腎疾患の治療法
JP2016252260A Pending JP2017095477A (ja) 2006-01-30 2016-12-27 慢性腎疾患の治療法
JP2017041248A Active JP6239169B2 (ja) 2006-01-30 2017-03-06 軟組織石灰化の回復、予防、遅延または安定化方法
JP2018006046A Pending JP2018109001A (ja) 2006-01-30 2018-01-18 慢性腎疾患の治療法
JP2019112469A Pending JP2019194212A (ja) 2006-01-30 2019-06-18 慢性腎疾患の治療法
JP2021159648A Pending JP2022020633A (ja) 2006-01-30 2021-09-29 慢性腎疾患の治療法
JP2023015069A Pending JP2023055886A (ja) 2006-01-30 2023-02-03 慢性腎疾患の治療法
JP2024168044A Pending JP2025016448A (ja) 2006-01-30 2024-09-27 慢性腎疾患の治療法

Family Applications After (13)

Application Number Title Priority Date Filing Date
JP2008552431A Pending JP2009525276A (ja) 2006-01-30 2007-01-26 慢性腎疾患の治療法
JP2013142389A Active JP6154226B2 (ja) 2006-01-30 2013-07-08 軟組織石灰化の回復、予防、遅延または安定化方法
JP2013142517A Pending JP2013227333A (ja) 2006-01-30 2013-07-08 慢性腎疾患の治療法
JP2014157464A Active JP6368186B2 (ja) 2006-01-30 2014-08-01 慢性腎疾患の治療法
JP2015180311A Active JP6632842B2 (ja) 2006-01-30 2015-09-14 慢性腎疾患の治療法
JP2016176150A Pending JP2017036289A (ja) 2006-01-30 2016-09-09 慢性腎疾患の治療法
JP2016252260A Pending JP2017095477A (ja) 2006-01-30 2016-12-27 慢性腎疾患の治療法
JP2017041248A Active JP6239169B2 (ja) 2006-01-30 2017-03-06 軟組織石灰化の回復、予防、遅延または安定化方法
JP2018006046A Pending JP2018109001A (ja) 2006-01-30 2018-01-18 慢性腎疾患の治療法
JP2019112469A Pending JP2019194212A (ja) 2006-01-30 2019-06-18 慢性腎疾患の治療法
JP2021159648A Pending JP2022020633A (ja) 2006-01-30 2021-09-29 慢性腎疾患の治療法
JP2023015069A Pending JP2023055886A (ja) 2006-01-30 2023-02-03 慢性腎疾患の治療法
JP2024168044A Pending JP2025016448A (ja) 2006-01-30 2024-09-27 慢性腎疾患の治療法

Country Status (11)

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US (8) US9750715B2 (https=)
EP (3) EP3066923B1 (https=)
JP (14) JP2009525277A (https=)
CN (4) CN101374416A (https=)
AU (2) AU2007210090B2 (https=)
CA (2) CA2640763C (https=)
DK (1) DK1978807T3 (https=)
ES (2) ES2699447T3 (https=)
HU (1) HUE028029T2 (https=)
IL (2) IL192545A (https=)
WO (2) WO2007089577A2 (https=)

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WO2012099139A1 (ja) * 2011-01-18 2012-07-26 日本たばこ産業株式会社 β酸化水酸化鉄を実質的に含まないクエン酸第二鉄
JP2016535780A (ja) * 2013-11-04 2016-11-17 ケリク バイオファーマシューティカルス, インコーポレーテッド 慢性腎臓病患者の心不全を軽減するためのクエン酸第二鉄
JP2020528888A (ja) * 2017-07-26 2020-10-01 ファーマヌトゥラ・エッセ・ピ・ア 心血管器官の病態の予防及び処置における使用のための組成物
US12246036B2 (en) 2017-08-02 2025-03-11 Pharmanutra S.P.A. Composition for use in the prevention and in the treatment of iron deficiency
US12297406B2 (en) 2019-05-27 2025-05-13 Alesco S.R.L. Method for preparing a composition comprising cetylated fatty acids
US12383525B2 (en) 2019-05-27 2025-08-12 Pharmanutra S.P.A. Compositions comprising cetylated fatty acids and use thereof for the treatment of arthritis and joint inflammatory conditions

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TWI335218B (en) * 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
EP3066923B1 (en) 2006-01-30 2025-11-05 Panion & BF Biotech Inc. Method of treating chronic kidney disease
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US8178709B2 (en) * 2009-07-21 2012-05-15 Biolink Life Sciences, Inc. Iron preparation suitable for pharmaceutical formulation and process for the preparation thereof
CN108938585A (zh) 2009-07-21 2018-12-07 凯克斯生物制药公司 柠檬酸铁剂型
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JP2012112785A (ja) * 2010-11-24 2012-06-14 Tohoku Univ 透析膜の評価方法
SG11201408521WA (en) 2012-06-21 2015-01-29 Keryx Biopharmaceuticals Inc Use of ferric citrate in the treatment of chronic kidney disease patients
JP6348495B2 (ja) * 2012-09-04 2018-06-27 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム シトレートに富むカルシウム・マグネシウム補助剤およびその使用
EP3157516A4 (en) * 2014-06-22 2017-12-13 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
JP2018526349A (ja) * 2015-08-05 2018-09-13 ルピン・リミテッド 医薬品グレードのクエン酸第二鉄の調製のためのプロセス
WO2018193648A1 (ja) * 2017-04-18 2018-10-25 国立大学法人東北大学 アルカリ性化剤による血液浄化
JP7578234B2 (ja) * 2017-04-18 2024-11-06 国立大学法人東北大学 アルカリ性化剤による血液浄化
JP7219898B2 (ja) * 2017-04-18 2023-02-09 国立大学法人東北大学 アルカリ性化剤による血液浄化
EP3737938B1 (en) * 2018-01-12 2023-10-25 Mayo Foundation for Medical Education and Research Systems and methods for the detection and quantification of ammonia and ammonium in fluids
WO2020018554A1 (en) * 2018-07-17 2020-01-23 The Regents Of The University Of California Methods of treating renal disease
KR20210076008A (ko) * 2018-10-17 2021-06-23 교토후고리츠다이가쿠호진 당뇨병 신증에 있어서의 신장 섬유화 억제제
EP3868371A4 (en) * 2018-10-17 2022-11-02 Tohoku University Novel pharmaceutical composition
US20220202752A1 (en) * 2019-04-28 2022-06-30 Tohoku University Novel pharmaceutical composition
JP7696926B2 (ja) * 2020-05-13 2025-06-23 コンパニー ゼネラール デ エタブリッスマン ミシュラン 濡れた地面上の寿命末期グリップが改善されたタイヤ
AU2022227671A1 (en) * 2021-02-24 2023-09-07 MoxxiTech, LLC Compositions and methods for treating canine parvovirus infection
CN117999069A (zh) 2021-05-27 2024-05-07 凯克斯生物制药公司 柠檬酸铁的儿科调配物
KR102623739B1 (ko) * 2022-07-28 2024-01-11 주식회사 페라메드 시트르산과 철을 포함하는 착화합물 및 그를 포함하는 식품 조성물

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