JP2009520031A5 - - Google Patents
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- Publication number
- JP2009520031A5 JP2009520031A5 JP2008547445A JP2008547445A JP2009520031A5 JP 2009520031 A5 JP2009520031 A5 JP 2009520031A5 JP 2008547445 A JP2008547445 A JP 2008547445A JP 2008547445 A JP2008547445 A JP 2008547445A JP 2009520031 A5 JP2009520031 A5 JP 2009520031A5
- Authority
- JP
- Japan
- Prior art keywords
- benzo
- dihydro
- group
- dioxinyl
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCCC(C)C(C*CC)C(*C1)[*@@]1C=C(C)C=C1CCCC1 Chemical compound CCCC(C)C(C*CC)C(*C1)[*@@]1C=C(C)C=C1CCCC1 0.000 description 5
- ZETAGARONYFXRI-UHFFFAOYSA-N CC(C)C1Oc2ccccc2O1 Chemical compound CC(C)C1Oc2ccccc2O1 ZETAGARONYFXRI-UHFFFAOYSA-N 0.000 description 1
- MJCYUVOCINOVJH-UHFFFAOYSA-N CC1Oc2ccccc2OC1 Chemical compound CC1Oc2ccccc2OC1 MJCYUVOCINOVJH-UHFFFAOYSA-N 0.000 description 1
- WEHANIYZRUPANY-UHFFFAOYSA-N IC1COc(cccc2)c2OC1 Chemical compound IC1COc(cccc2)c2OC1 WEHANIYZRUPANY-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75149405P | 2005-12-19 | 2005-12-19 | |
| US60/751,494 | 2005-12-19 | ||
| US11/612,146 | 2006-12-18 | ||
| US11/612,146 US20070155823A1 (en) | 2005-12-19 | 2006-12-18 | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
| PCT/US2006/048451 WO2007075698A2 (en) | 2005-12-19 | 2006-12-19 | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009520031A JP2009520031A (ja) | 2009-05-21 |
| JP2009520031A5 true JP2009520031A5 (https=) | 2010-10-21 |
| JP5190373B2 JP5190373B2 (ja) | 2013-04-24 |
Family
ID=37951698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008547445A Expired - Fee Related JP5190373B2 (ja) | 2005-12-19 | 2006-12-19 | 神経防護薬としてのベンゾ縮合複素環スルファミド誘導体の使用 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20070155823A1 (https=) |
| EP (1) | EP1968571B1 (https=) |
| JP (1) | JP5190373B2 (https=) |
| KR (1) | KR20080089405A (https=) |
| AT (1) | ATE536182T1 (https=) |
| AU (1) | AU2006331783A1 (https=) |
| BR (1) | BRPI0620060A2 (https=) |
| CA (1) | CA2634088A1 (https=) |
| CR (1) | CR10171A (https=) |
| CY (1) | CY1112444T1 (https=) |
| DK (1) | DK1968571T3 (https=) |
| EA (1) | EA016628B1 (https=) |
| ES (1) | ES2375845T3 (https=) |
| HR (1) | HRP20120018T1 (https=) |
| IL (1) | IL192106A0 (https=) |
| MY (1) | MY149175A (https=) |
| NO (1) | NO20083033L (https=) |
| NZ (1) | NZ569041A (https=) |
| PL (1) | PL1968571T3 (https=) |
| PT (1) | PT1968571E (https=) |
| RS (1) | RS52220B (https=) |
| SI (1) | SI1968571T1 (https=) |
| WO (1) | WO2007075698A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| KR20080012360A (ko) * | 2005-05-20 | 2008-02-11 | 얀센 파마슈티카 엔.브이. | 설파미드 유도체의 제조 방법 |
| US8497298B2 (en) | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| US8691867B2 (en) | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| EA200870556A1 (ru) * | 2006-05-19 | 2009-06-30 | Янссен Фармацевтика Н.В. | Комбинированная терапия в лечении эпилепсии и родственных расстройств |
| US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
| US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
| JP2011519839A (ja) * | 2008-04-29 | 2011-07-14 | エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ | ドーパミン神経伝達のモジュレーター |
| EP2271638B1 (en) * | 2008-04-29 | 2011-08-31 | NSAB, Filial af NeuroSearch Sweden AB, Sverige | Modulators of dopamine neurotransmission |
| MX2010011724A (es) * | 2008-04-29 | 2010-11-30 | Nsab Af Neurosearch Sweden Ab | Moduladores de neurotransmision de dopamina. |
| EA018567B1 (ru) | 2008-06-23 | 2013-08-30 | Янссен Фармацевтика Нв | Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида |
| TWI406596B (zh) | 2008-06-30 | 2013-08-21 | Green Solution Tech Co Ltd | 發光二極體驅動電路、發光二極體驅動控制單元及其電晶體開關模組 |
| US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| JP2014528953A (ja) | 2011-09-29 | 2014-10-30 | ヤンセン ファーマシューティカ エヌ.ベー. | スルファミド誘導体の調製プロセス |
| KR20140082762A (ko) | 2011-09-29 | 2014-07-02 | 얀센 파마슈티카 엔.브이. | 설파미드 유도체의 개선된 제조 방법 |
| MX355261B (es) * | 2012-06-21 | 2018-04-12 | Eisai R&D Man Co Ltd | Derivado de indanosulfamida novedoso. |
| KR20200132858A (ko) | 2018-03-20 | 2020-11-25 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 간질 치료제 |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2527861A (en) * | 1948-05-07 | 1950-10-31 | Monsanto Chemicals | Mono alkyl sulfamides |
| BE636655A (https=) * | 1962-09-14 | |||
| US3318952A (en) * | 1964-01-22 | 1967-05-09 | Sandoz Ag | Dibenzylsulfamides |
| US3383414A (en) * | 1964-08-26 | 1968-05-14 | Sandoz Ag | Benzocycloalkyl sulfamides |
| US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| US3621096A (en) * | 1969-04-03 | 1971-11-16 | Univ North Carolina | Antidepressant method and composition for same comprising a tricyclic antidepressant and a thyroid hormone |
| US5212326A (en) * | 1979-08-20 | 1993-05-18 | Abbott Laboratories | Sodium hydrogen divalproate oligomer |
| FR2479825A1 (fr) * | 1980-04-04 | 1981-10-09 | Fabre Sa Pierre | Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments |
| US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
| US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| US4831031A (en) * | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
| US5158952A (en) * | 1988-11-07 | 1992-10-27 | Janssen Pharmaceutica N.V. | 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use |
| US5238945A (en) * | 1989-04-11 | 1993-08-24 | H. Lundbeck A/S | Method of treating psychoses |
| GB8908085D0 (en) * | 1989-04-11 | 1989-05-24 | Lundbeck & Co As H | New therapeutic use |
| US5273993A (en) * | 1989-06-12 | 1993-12-28 | A. H. Robins Company, Incorporated | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals |
| US5194446A (en) * | 1989-06-12 | 1993-03-16 | A. H. Robins Company, Incorporated | Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals |
| US5192785A (en) * | 1989-09-03 | 1993-03-09 | A. H. Robins Company, Incorporated | Sulfamates as antiglaucoma agents |
| US5229382A (en) * | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
| IL103172A (en) * | 1991-09-19 | 1997-01-10 | Mcneilab Inc | Preparation of chlorosulfate and sulfamate derivatives of 2, 3:4, 5-bis-o-(1-methylethylidene)-beta-d-fructopyranose and (1-methylcyclohexyl) methanol |
| US5242942A (en) * | 1992-04-28 | 1993-09-07 | Mcneilab, Inc. | Anticonvulsant fructopyranose cyclic sulfites and sulfates |
| US5258402A (en) * | 1992-06-11 | 1993-11-02 | Mcneil-Ppc, Inc. | Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates |
| US5312925A (en) * | 1992-09-01 | 1994-05-17 | Pfizer Inc. | Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride |
| US5384327A (en) * | 1992-12-22 | 1995-01-24 | Mcneilab, Inc. | Anticonvulsant sorbopyranose sulfamates |
| JPH11501619A (ja) * | 1995-02-15 | 1999-02-09 | ベアーズデン バイオ,インコーポレイテッド | アルキルカルボキシアミノ酸−カイネートレセプターのモジュレーター |
| JP3235448B2 (ja) * | 1995-03-24 | 2001-12-04 | ダイソー株式会社 | 1,4−ベンゾジオキサン誘導体の製法 |
| US5998380A (en) * | 1995-10-13 | 1999-12-07 | New England Medical Center Hospitals, Inc. | Treatment of migraine |
| AU1328197A (en) * | 1995-12-01 | 1997-06-19 | Synaptic Pharmaceutical Corporation | Aryl sulfonamide and sulfamide derivatives and uses thereof |
| RU2214241C2 (ru) * | 1996-06-28 | 2003-10-20 | Орто-Макнейл Фармасьютикал, Инк. | Способ лечения ожирения и способ индуцирования потери веса у млекопитающих |
| US5753693A (en) * | 1996-06-28 | 1998-05-19 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating manic-depressive bipolar disorder |
| US5753694A (en) * | 1996-06-28 | 1998-05-19 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS) |
| WO1998007447A1 (en) * | 1996-08-23 | 1998-02-26 | Algos Pharmaceutical Corporation | Anticonvulsant containing composition for treating neuropathic pain |
| US20020015713A1 (en) * | 1996-10-24 | 2002-02-07 | Murdock Robert W. | Methods and transdermal compositions for pain relief |
| US5935933A (en) * | 1997-07-16 | 1999-08-10 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating neuropathic pain |
| US5760007A (en) * | 1997-07-16 | 1998-06-02 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating neuropathic pain |
| EP1014959B1 (en) * | 1997-08-15 | 2004-10-20 | Carolyn Ann Fairbanks | Agmatine as a treatment for neuropathic pain |
| ATE279921T1 (de) * | 1999-01-19 | 2004-11-15 | Ortho Mcneil Pharm Inc | Verwendung von antikonvulsiven derivaten zur behandlung der cluster headache |
| ATE294577T1 (de) * | 1999-02-24 | 2005-05-15 | Univ Cincinnati | Verwendung von sulfamat derivaten zur behandlung von impulsiven störungen |
| US6191163B1 (en) * | 1999-04-08 | 2001-02-20 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in lowering lipids |
| WO2000061138A1 (en) * | 1999-04-08 | 2000-10-19 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders |
| PL213323B1 (pl) * | 1999-08-20 | 2013-02-28 | Ortho Mcneil Pharm Inc | Kompozycja farmaceutyczna i jej zastosowanie |
| US6322503B1 (en) * | 2000-02-17 | 2001-11-27 | G. Roger Sparhawk, Jr. | Method of diagnosing, tracking, and treating depression |
| CA2415093A1 (en) * | 2000-07-07 | 2002-01-17 | Carlos Plata-Salaman | Anticonvulsant derivatives useful for preventing the development of type ii diabetes mellitus and syndrome x |
| EP1309325A1 (en) * | 2000-08-02 | 2003-05-14 | Ortho-McNeil Pharmaceutical, Inc. | Anticonvulsant derivatives useful for the treatment of depression |
| US7256184B2 (en) * | 2000-10-16 | 2007-08-14 | Rodriguez Victorio C | Treatment of aging disorders in humans |
| EP1357908A4 (en) * | 2001-01-30 | 2009-07-15 | Merck & Co Inc | "ACYLSULFAMIDES FOR THE TREATMENT OF FATIBILITY, DIABETES AND LIPID DISORDERS" |
| US20030100594A1 (en) * | 2001-08-10 | 2003-05-29 | Pharmacia Corporation | Carbonic anhydrase inhibitor |
| US6559293B1 (en) * | 2002-02-15 | 2003-05-06 | Transform Pharmaceuticals, Inc. | Topiramate sodium trihydrate |
| US8637512B2 (en) * | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
| US6949518B1 (en) * | 2003-06-25 | 2005-09-27 | Pao-Hsien Chu | Methods for treating macular degeneration with topiramate |
| CN1897950A (zh) * | 2003-10-14 | 2007-01-17 | 惠氏公司 | 稠合芳基和杂芳基衍生物及其使用方法 |
| AR049646A1 (es) * | 2004-06-16 | 2006-08-23 | Janssen Pharmaceutica Nv | Derivados de sulfamato y sulfamida utiles para el tratamiento de la epilepsia y trastornos relacionados |
| US20060276528A1 (en) * | 2004-08-24 | 2006-12-07 | Abdel-Magid Ahmed F | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents |
| DE602005008084D1 (de) * | 2004-08-24 | 2008-08-21 | Janssen Pharmaceutica Nv | Als antikonvulsive mittel geeignete neue benzokondensierte heteroarylsulfamidderivate |
| CA2605580A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Benzodioxane and benzodioxolane derivatives and uses thereof |
| KR20080012360A (ko) * | 2005-05-20 | 2008-02-11 | 얀센 파마슈티카 엔.브이. | 설파미드 유도체의 제조 방법 |
| US20070155824A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for disease modification / epileptogenesis |
| US20070293476A1 (en) * | 2006-05-19 | 2007-12-20 | Smith-Swintosky Virginia L | Co-therapy for the treatment of epilepsy and related disorders |
| EA200870556A1 (ru) * | 2006-05-19 | 2009-06-30 | Янссен Фармацевтика Н.В. | Комбинированная терапия в лечении эпилепсии и родственных расстройств |
| EP2238122A1 (en) * | 2008-01-07 | 2010-10-13 | Janssen Pharmaceutica, N.V. | Preparation of sulfamide derivatives |
| US20090247618A1 (en) * | 2008-03-26 | 2009-10-01 | Ballentine Scott A | Process for preparation of benzo-fused heteroaryl derivatives |
| US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
| EA018567B1 (ru) * | 2008-06-23 | 2013-08-30 | Янссен Фармацевтика Нв | Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида |
| US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
-
2006
- 2006-12-18 US US11/612,146 patent/US20070155823A1/en not_active Abandoned
- 2006-12-19 HR HR20120018T patent/HRP20120018T1/hr unknown
- 2006-12-19 PT PT06845823T patent/PT1968571E/pt unknown
- 2006-12-19 AT AT06845823T patent/ATE536182T1/de active
- 2006-12-19 EP EP06845823A patent/EP1968571B1/en active Active
- 2006-12-19 RS RS20120057A patent/RS52220B/sr unknown
- 2006-12-19 SI SI200631254T patent/SI1968571T1/sl unknown
- 2006-12-19 NZ NZ569041A patent/NZ569041A/en not_active IP Right Cessation
- 2006-12-19 KR KR1020087017501A patent/KR20080089405A/ko not_active Ceased
- 2006-12-19 ES ES06845823T patent/ES2375845T3/es active Active
- 2006-12-19 AU AU2006331783A patent/AU2006331783A1/en not_active Abandoned
- 2006-12-19 WO PCT/US2006/048451 patent/WO2007075698A2/en not_active Ceased
- 2006-12-19 MY MYPI20082184A patent/MY149175A/en unknown
- 2006-12-19 CA CA002634088A patent/CA2634088A1/en not_active Abandoned
- 2006-12-19 EA EA200870087A patent/EA016628B1/ru not_active IP Right Cessation
- 2006-12-19 PL PL06845823T patent/PL1968571T3/pl unknown
- 2006-12-19 BR BRPI0620060-5A patent/BRPI0620060A2/pt not_active IP Right Cessation
- 2006-12-19 JP JP2008547445A patent/JP5190373B2/ja not_active Expired - Fee Related
- 2006-12-19 DK DK06845823.1T patent/DK1968571T3/da active
-
2008
- 2008-06-12 IL IL192106A patent/IL192106A0/en unknown
- 2008-07-04 NO NO20083033A patent/NO20083033L/no not_active Application Discontinuation
- 2008-07-21 CR CR10171A patent/CR10171A/es not_active Application Discontinuation
-
2012
- 2012-02-23 CY CY20121100189T patent/CY1112444T1/el unknown
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