JP2009517345A - 創傷治癒の方法 - Google Patents
創傷治癒の方法 Download PDFInfo
- Publication number
- JP2009517345A JP2009517345A JP2008541550A JP2008541550A JP2009517345A JP 2009517345 A JP2009517345 A JP 2009517345A JP 2008541550 A JP2008541550 A JP 2008541550A JP 2008541550 A JP2008541550 A JP 2008541550A JP 2009517345 A JP2009517345 A JP 2009517345A
- Authority
- JP
- Japan
- Prior art keywords
- euphorbia
- wound
- ingenol
- subject
- pep005
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2005906601A AU2005906601A0 (en) | 2005-11-25 | Therapeutic methods and compositions | |
| PCT/AU2006/001781 WO2007059584A1 (en) | 2005-11-25 | 2006-11-24 | Methods for wound healing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009517345A true JP2009517345A (ja) | 2009-04-30 |
| JP2009517345A5 JP2009517345A5 (enExample) | 2009-12-17 |
Family
ID=38066849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008541550A Pending JP2009517345A (ja) | 2005-11-25 | 2006-11-24 | 創傷治癒の方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20090215884A1 (enExample) |
| EP (1) | EP1965818A4 (enExample) |
| JP (1) | JP2009517345A (enExample) |
| KR (1) | KR20080077625A (enExample) |
| CN (1) | CN101360506A (enExample) |
| BR (1) | BRPI0618926A2 (enExample) |
| CA (1) | CA2629899A1 (enExample) |
| NZ (1) | NZ568168A (enExample) |
| WO (1) | WO2007059584A1 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009242323A (ja) * | 2008-03-31 | 2009-10-22 | Naris Cosmetics Co Ltd | ケラチノサイト増殖促進剤 |
| JP2013525300A (ja) * | 2010-04-16 | 2013-06-20 | レオ ファーマ アクティーゼルスカブ | 結晶性インゲノールメブテート |
| JP2013530224A (ja) * | 2010-06-30 | 2013-07-25 | エイボン プロダクツ インコーポレーテッド | Magp−1に刺激を与えて皮膚の外観を改善する組成物及び方法 |
| JP2014507396A (ja) * | 2010-12-22 | 2014-03-27 | レオ・ラボラトリーズ・リミテッド | イノゲノール−3−アシラートi |
| JP2014507393A (ja) * | 2010-12-22 | 2014-03-27 | レオ・ラボラトリーズ・リミテッド | 3−アシル−イノゲノールii |
| JPWO2014104064A1 (ja) * | 2012-12-26 | 2017-01-12 | 株式会社エーゼット | 創傷治癒促進剤 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ801700A0 (en) | 2000-06-07 | 2000-06-29 | Peplin Research Pty Ltd | Enzyme and viral activation |
| NZ583157A (en) | 2004-12-13 | 2011-12-22 | Leo Lab Ltd | Treatment of solid cancers with angeloyl substituted ingenanes |
| PT2395993T (pt) * | 2009-02-13 | 2017-07-18 | Leo Laboratories Ltd | Tratamento cutâneo |
| KR102499738B1 (ko) | 2009-08-26 | 2023-02-13 | 마리 케이 인코포레이티드 | 식물 추출물을 포함하는 국소 피부 케어 제형 |
| WO2012080466A2 (en) | 2010-12-17 | 2012-06-21 | Leo Pharma A/S | Ingenols for treating seborrheic keratosis |
| JP5845283B2 (ja) * | 2010-12-22 | 2016-01-20 | レオ・ラボラトリーズ・リミテッドLeo Laboratories Limited | インゲノール−3−アシラートiiiおよびインゲノール−3−カルバメート |
| WO2012176015A1 (en) * | 2011-06-24 | 2012-12-27 | Leo Pharma A/S | Methods for treating uv-damaged skin and scc tumors and for removing tattoos with topical ingenol mebutate |
| GB201110777D0 (en) | 2011-06-24 | 2011-08-10 | Aqua Bio Technology Asa | Methods and uses |
| EP2790669A1 (en) * | 2011-12-12 | 2014-10-22 | Leo Laboratories Limited | A topical composition comprising an ingenol derivative and an oily solvent |
| US20130251782A1 (en) * | 2012-03-22 | 2013-09-26 | Leo Laboratories Limited | Topical application of ingenol mebutate with occlusion |
| MX2014015497A (es) * | 2012-06-26 | 2015-03-06 | Leo Lab Ltd | 3-o-heteroaril-ingenol. |
| KR20150027831A (ko) * | 2012-07-06 | 2015-03-12 | 레오 파마 에이/에스 | 피부에 활성 성분을 전달하기 위한 막-형성 중합체를 포함하는 국소 조성물 |
| WO2014158858A1 (en) * | 2013-03-13 | 2014-10-02 | Avon Products, Inc | Glochidium wallichianum extracts and methods of use |
| CN105055448A (zh) * | 2015-05-25 | 2015-11-18 | 中国人民解放军第三军医大学第一附属医院 | 铜离子制剂在制备促进皮肤角质形成细胞增殖药物或敷料中的用途 |
| US20190192636A1 (en) * | 2016-03-18 | 2019-06-27 | Intrexon Corporation | Compositions and methods for treatment of type viii collagen deficiencies |
| CN106619600B (zh) * | 2016-03-28 | 2019-10-18 | 中国科学院遗传与发育生物学研究所 | 巨大戟醇及其衍生物在增强溶酶体生成中的应用 |
| CN115677520B (zh) * | 2022-11-18 | 2024-04-02 | 扬州大学 | 一种二萜化合物及其制备方法和应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002535138A (ja) * | 1999-01-29 | 2002-10-22 | シデ ソシエテ インダストリエーレ ド ラ ドゥ エス アー | 少なくとも1個の回転軸を備えた粉砕装置 |
| JP2003506488A (ja) * | 1999-08-13 | 2003-02-18 | フォトゲン インク | 疾患の光線力学的療法のための改良された局所用薬品および方法 |
| JP2003535136A (ja) * | 2000-06-07 | 2003-11-25 | ペプリン リサーチ プロプライエタリー リミティッド | 治療効果のある物質−iii |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3809749A (en) * | 1971-03-05 | 1974-05-07 | Amazon Natural Drug Co | Topical pharmaceutical composition and method employing sap from the tree croton lechleri |
| DE2902506A1 (de) * | 1979-01-23 | 1980-07-24 | Deutsches Krebsforsch | Verwendung von nicht oder nur gering irritierenden und/oder promovierenden diterpenalkoholen und von derivaten davon als antineoplastische mittel |
| US4418064A (en) * | 1982-09-29 | 1983-11-29 | The United States Of America As Represented By The Secretary Of Agriculture | Chemotherapeutically active maytansinoids: treflorine, trenudine, and N-methyltrenudone |
| US4560774A (en) * | 1982-11-17 | 1985-12-24 | Arizona State University | Macrocyclic lactones |
| US5886019A (en) * | 1986-06-11 | 1999-03-23 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. F. |
| US5962498A (en) * | 1986-06-11 | 1999-10-05 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity |
| US5891870A (en) * | 1986-06-11 | 1999-04-06 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators Q |
| US5891906A (en) * | 1986-06-11 | 1999-04-06 | Procyon Pharmaceuticals, Inc. | Polyacetate-derived phorboids having anti-inflammatory and other uses |
| US5643948A (en) * | 1986-06-11 | 1997-07-01 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. K. |
| US5886017A (en) * | 1986-06-11 | 1999-03-23 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. E. |
| US5750568A (en) * | 1986-06-11 | 1998-05-12 | Procyon Pharmaceuticals, Inc. | Protein kinase C Modulators. L. |
| US5716968A (en) * | 1986-06-11 | 1998-02-10 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. H. |
| US5145842A (en) * | 1986-06-11 | 1992-09-08 | Alder Research Center Limited Partnership | Protein kinase c. modulators. d. |
| DE4102054A1 (de) * | 1991-01-24 | 1992-07-30 | Geb Szenasi Tamas | Verwendung der pflanze euphorbia hirta l. und ihrer extrakte sowie ihrer wirkstoffe |
| US5863938A (en) * | 1991-03-01 | 1999-01-26 | Warner Lambert Company | Antibacterial-wound healing compositions and methods for preparing and using same |
| US5317009A (en) * | 1991-08-26 | 1994-05-31 | New York University | Anti-HIV proteins GAP 31, DAP 30 and DAP 32 and therapeutic uses thereof |
| US6593371B1 (en) * | 1993-05-19 | 2003-07-15 | Jeff J. Staggs | Treatment for wart and related disorders |
| US5874464A (en) * | 1995-01-13 | 1999-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Conformationally constrained diacylglycerol analogues |
| US5932613A (en) * | 1996-07-03 | 1999-08-03 | Millennium Pharmaceuticals, Inc. | Anticancer agents |
| AUPO864097A0 (en) * | 1997-08-19 | 1997-09-11 | Peplin Pty Ltd | Anti-cancer compounds |
| JP2001139468A (ja) * | 1999-11-11 | 2001-05-22 | Lead Chemical Co Ltd | 抗ウイルス作用を有するホルボール誘導体 |
| AUPQ923100A0 (en) * | 2000-08-07 | 2000-08-31 | Peplin Research Pty Ltd | Treatment of prostate cancer |
| US6923993B2 (en) * | 2001-12-12 | 2005-08-02 | Nicholas J. Donato | Process of isolating extract from the Euphorbia obesa plant and methods for using the same |
| US7390499B2 (en) * | 2002-04-26 | 2008-06-24 | Lohmann & Rauscher Gmbh | Microbial cellulose wound dressing for treating chronic wounds |
| WO2005043155A1 (en) * | 2003-10-21 | 2005-05-12 | Cedars-Sinai Medical Center | System and method for the treatment of cancer, including cancers of the central nervous system |
| CA2552411A1 (en) * | 2004-01-01 | 2005-07-21 | Panacea Biotec Ltd. | Pharmaceutical compositions comprising an extract of euphorbia prostrata |
| BRPI0504797B1 (pt) * | 2005-10-27 | 2020-02-04 | Pele Nova Biotecnologia S.A. | formulação tópica, método de tratamento cosmético para rejuvenescimento da pele, método de tratamento cosmético e uso de uma formulação |
-
2006
- 2006-11-24 KR KR1020087014376A patent/KR20080077625A/ko not_active Ceased
- 2006-11-24 WO PCT/AU2006/001781 patent/WO2007059584A1/en not_active Ceased
- 2006-11-24 NZ NZ568168A patent/NZ568168A/en not_active IP Right Cessation
- 2006-11-24 JP JP2008541550A patent/JP2009517345A/ja active Pending
- 2006-11-24 BR BRPI0618926-1A patent/BRPI0618926A2/pt not_active IP Right Cessation
- 2006-11-24 CN CNA2006800516339A patent/CN101360506A/zh active Pending
- 2006-11-24 CA CA002629899A patent/CA2629899A1/en not_active Abandoned
- 2006-11-24 US US12/094,713 patent/US20090215884A1/en not_active Abandoned
- 2006-11-24 EP EP06817537A patent/EP1965818A4/en not_active Withdrawn
-
2016
- 2016-04-18 US US15/131,851 patent/US20160317486A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002535138A (ja) * | 1999-01-29 | 2002-10-22 | シデ ソシエテ インダストリエーレ ド ラ ドゥ エス アー | 少なくとも1個の回転軸を備えた粉砕装置 |
| JP2003506488A (ja) * | 1999-08-13 | 2003-02-18 | フォトゲン インク | 疾患の光線力学的療法のための改良された局所用薬品および方法 |
| JP2003535136A (ja) * | 2000-06-07 | 2003-11-25 | ペプリン リサーチ プロプライエタリー リミティッド | 治療効果のある物質−iii |
| JP2003535137A (ja) * | 2000-06-07 | 2003-11-25 | ペプリン リサーチ プロプライエタリー リミティッド | 治療効果のある物質−i |
Non-Patent Citations (1)
| Title |
|---|
| JPN7012002029; P. Hampson et.al.: '"PEP-005 Treatment of Actinic Keratoses Acute Myeloid Leukemia Therapy Treatment of Basal Cell Carci' Drugs of the Future Vol.30, No.10, 2005, p.1003-1005 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009242323A (ja) * | 2008-03-31 | 2009-10-22 | Naris Cosmetics Co Ltd | ケラチノサイト増殖促進剤 |
| JP2013525300A (ja) * | 2010-04-16 | 2013-06-20 | レオ ファーマ アクティーゼルスカブ | 結晶性インゲノールメブテート |
| JP2013530224A (ja) * | 2010-06-30 | 2013-07-25 | エイボン プロダクツ インコーポレーテッド | Magp−1に刺激を与えて皮膚の外観を改善する組成物及び方法 |
| JP2014507396A (ja) * | 2010-12-22 | 2014-03-27 | レオ・ラボラトリーズ・リミテッド | イノゲノール−3−アシラートi |
| JP2014507393A (ja) * | 2010-12-22 | 2014-03-27 | レオ・ラボラトリーズ・リミテッド | 3−アシル−イノゲノールii |
| JPWO2014104064A1 (ja) * | 2012-12-26 | 2017-01-12 | 株式会社エーゼット | 創傷治癒促進剤 |
| US9962364B2 (en) | 2012-12-26 | 2018-05-08 | A-Z Ltd. | Wound healing accelerator |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ568168A (en) | 2012-06-29 |
| BRPI0618926A2 (pt) | 2011-09-13 |
| EP1965818A1 (en) | 2008-09-10 |
| KR20080077625A (ko) | 2008-08-25 |
| CN101360506A (zh) | 2009-02-04 |
| WO2007059584A1 (en) | 2007-05-31 |
| US20160317486A1 (en) | 2016-11-03 |
| EP1965818A4 (en) | 2010-02-17 |
| US20090215884A1 (en) | 2009-08-27 |
| CA2629899A1 (en) | 2007-05-31 |
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