BRPI0618926A2 - uso de um composto de ingenol ou um sal farmaceuticamente aceitável do mesmo - Google Patents
uso de um composto de ingenol ou um sal farmaceuticamente aceitável do mesmo Download PDFInfo
- Publication number
- BRPI0618926A2 BRPI0618926A2 BRPI0618926-1A BRPI0618926A BRPI0618926A2 BR PI0618926 A2 BRPI0618926 A2 BR PI0618926A2 BR PI0618926 A BRPI0618926 A BR PI0618926A BR PI0618926 A2 BRPI0618926 A2 BR PI0618926A2
- Authority
- BR
- Brazil
- Prior art keywords
- euphorbia
- wound
- ingenol
- optionally substituted
- pharmaceutically acceptable
- Prior art date
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| AU2005906601 | 2005-11-25 | ||
| AU2005906601A AU2005906601A0 (en) | 2005-11-25 | Therapeutic methods and compositions | |
| PCT/AU2006/001781 WO2007059584A1 (en) | 2005-11-25 | 2006-11-24 | Methods for wound healing |
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| BRPI0618926A2 true BRPI0618926A2 (pt) | 2011-09-13 |
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| BRPI0618926-1A BRPI0618926A2 (pt) | 2005-11-25 | 2006-11-24 | uso de um composto de ingenol ou um sal farmaceuticamente aceitável do mesmo |
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| JP (1) | JP2009517345A (enExample) |
| KR (1) | KR20080077625A (enExample) |
| CN (1) | CN101360506A (enExample) |
| BR (1) | BRPI0618926A2 (enExample) |
| CA (1) | CA2629899A1 (enExample) |
| NZ (1) | NZ568168A (enExample) |
| WO (1) | WO2007059584A1 (enExample) |
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| AUPQ801700A0 (en) | 2000-06-07 | 2000-06-29 | Peplin Research Pty Ltd | Enzyme and viral activation |
| NZ583157A (en) | 2004-12-13 | 2011-12-22 | Leo Lab Ltd | Treatment of solid cancers with angeloyl substituted ingenanes |
| JP5291369B2 (ja) * | 2008-03-31 | 2013-09-18 | 株式会社ナリス化粧品 | ケラチノサイト増殖促進剤 |
| CA2752389C (en) * | 2009-02-13 | 2017-01-03 | Peplin Research Pty Ltd | Use of ingenols in the treatment of aged skin |
| KR101769294B1 (ko) | 2009-08-26 | 2017-08-18 | 마리 케이 인코포레이티드 | 식물 추출물을 포함하는 국소 피부 케어 제형 |
| HUE034138T2 (en) | 2010-04-16 | 2018-01-29 | Leo Pharma As | Orthopedic crystalline ingenol mebuta |
| MX2012013787A (es) * | 2010-06-30 | 2012-12-17 | Avon Prod Inc | Composiciones y metodos para estimular magp-1 y mejorar la apariencia de la piel. |
| US9402823B2 (en) | 2010-12-17 | 2016-08-02 | Leo Laboratories Limited | Ingenols for treating seborrheic keratosis |
| TWI591047B (zh) * | 2010-12-22 | 2017-07-11 | 理奧實驗有限公司 | 巨大戟萜醇-3-醯化物iii及巨大戟萜醇-3-胺基甲酸酯化物 |
| BR112013015859A2 (pt) * | 2010-12-22 | 2018-11-21 | Leo Laboratories Ltd | composto, uso de um composto, métodos de prevenção, tratamento, melhora ou profilaxia de distúrbios fisiológicos ou doenças, e de tratamento ou melhora de indicações cosméticas, e, composição farmacêutica |
| EP2655311A1 (en) | 2010-12-22 | 2013-10-30 | Leo Laboratories Limited | Ingenol-3-acylates i |
| GB201110777D0 (en) | 2011-06-24 | 2011-08-10 | Aqua Bio Technology Asa | Methods and uses |
| WO2012176015A1 (en) * | 2011-06-24 | 2012-12-27 | Leo Pharma A/S | Methods for treating uv-damaged skin and scc tumors and for removing tattoos with topical ingenol mebutate |
| US20140348905A1 (en) * | 2011-12-12 | 2014-11-27 | Leo Laboratories Limited | Gel compositions |
| US20130251782A1 (en) * | 2012-03-22 | 2013-09-26 | Leo Laboratories Limited | Topical application of ingenol mebutate with occlusion |
| JP6216781B2 (ja) * | 2012-06-26 | 2017-10-18 | レオ・ラボラトリーズ・リミテッドLeo Laboratories Limited | 3−o−ヘテロアリール−インゲノール |
| AU2013285409B2 (en) * | 2012-07-06 | 2018-03-15 | Leo Pharma A/S | A topical composition comprising a film-forming polymer for delivering an active ingredient to skin |
| US9962364B2 (en) | 2012-12-26 | 2018-05-08 | A-Z Ltd. | Wound healing accelerator |
| WO2014158858A1 (en) * | 2013-03-13 | 2014-10-02 | Avon Products, Inc | Glochidium wallichianum extracts and methods of use |
| CN105055448A (zh) * | 2015-05-25 | 2015-11-18 | 中国人民解放军第三军医大学第一附属医院 | 铜离子制剂在制备促进皮肤角质形成细胞增殖药物或敷料中的用途 |
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| CN115677520B (zh) * | 2022-11-18 | 2024-04-02 | 扬州大学 | 一种二萜化合物及其制备方法和应用 |
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| US3809749A (en) * | 1971-03-05 | 1974-05-07 | Amazon Natural Drug Co | Topical pharmaceutical composition and method employing sap from the tree croton lechleri |
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| US4418064A (en) * | 1982-09-29 | 1983-11-29 | The United States Of America As Represented By The Secretary Of Agriculture | Chemotherapeutically active maytansinoids: treflorine, trenudine, and N-methyltrenudone |
| US4560774A (en) * | 1982-11-17 | 1985-12-24 | Arizona State University | Macrocyclic lactones |
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| US6593371B1 (en) * | 1993-05-19 | 2003-07-15 | Jeff J. Staggs | Treatment for wart and related disorders |
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-
2006
- 2006-11-24 NZ NZ568168A patent/NZ568168A/en not_active IP Right Cessation
- 2006-11-24 WO PCT/AU2006/001781 patent/WO2007059584A1/en not_active Ceased
- 2006-11-24 CA CA002629899A patent/CA2629899A1/en not_active Abandoned
- 2006-11-24 BR BRPI0618926-1A patent/BRPI0618926A2/pt not_active IP Right Cessation
- 2006-11-24 KR KR1020087014376A patent/KR20080077625A/ko not_active Ceased
- 2006-11-24 US US12/094,713 patent/US20090215884A1/en not_active Abandoned
- 2006-11-24 EP EP06817537A patent/EP1965818A4/en not_active Withdrawn
- 2006-11-24 CN CNA2006800516339A patent/CN101360506A/zh active Pending
- 2006-11-24 JP JP2008541550A patent/JP2009517345A/ja active Pending
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2016
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| US20160317486A1 (en) | 2016-11-03 |
| EP1965818A1 (en) | 2008-09-10 |
| EP1965818A4 (en) | 2010-02-17 |
| WO2007059584A1 (en) | 2007-05-31 |
| NZ568168A (en) | 2012-06-29 |
| KR20080077625A (ko) | 2008-08-25 |
| CN101360506A (zh) | 2009-02-04 |
| JP2009517345A (ja) | 2009-04-30 |
| US20090215884A1 (en) | 2009-08-27 |
| CA2629899A1 (en) | 2007-05-31 |
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