JP2009185061A5 - - Google Patents
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- Publication number
- JP2009185061A5 JP2009185061A5 JP2009115044A JP2009115044A JP2009185061A5 JP 2009185061 A5 JP2009185061 A5 JP 2009185061A5 JP 2009115044 A JP2009115044 A JP 2009115044A JP 2009115044 A JP2009115044 A JP 2009115044A JP 2009185061 A5 JP2009185061 A5 JP 2009185061A5
- Authority
- JP
- Japan
- Prior art keywords
- drug delivery
- transdermal drug
- fentanyl
- acrylate
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000013271 transdermal drug delivery Methods 0.000 claims 9
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 claims 7
- 229960002428 fentanyl Drugs 0.000 claims 7
- 239000000178 monomer Substances 0.000 claims 6
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical group OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- OWPUOLBODXJOKH-UHFFFAOYSA-N 2,3-dihydroxypropyl prop-2-enoate Chemical compound OCC(O)COC(=O)C=C OWPUOLBODXJOKH-UHFFFAOYSA-N 0.000 claims 1
- GOXQRTZXKQZDDN-UHFFFAOYSA-N 2-Ethylhexyl acrylate Chemical compound CCCCC(CC)COC(=O)C=C GOXQRTZXKQZDDN-UHFFFAOYSA-N 0.000 claims 1
- DXPPIEDUBFUSEZ-UHFFFAOYSA-N 6-methylheptyl prop-2-enoate Chemical group CC(C)CCCCCOC(=O)C=C DXPPIEDUBFUSEZ-UHFFFAOYSA-N 0.000 claims 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical group NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 claims 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- 125000005250 alkyl acrylate group Chemical group 0.000 claims 1
- -1 alkyl methacrylates Chemical class 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 claims 1
- 125000005392 carboxamide group Chemical group NC(=O)* 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- KBLWLMPSVYBVDK-UHFFFAOYSA-N cyclohexyl prop-2-enoate Chemical compound C=CC(=O)OC1CCCCC1 KBLWLMPSVYBVDK-UHFFFAOYSA-N 0.000 claims 1
- 125000000524 functional group Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- OVHHHVAVHBHXAK-UHFFFAOYSA-N n,n-diethylprop-2-enamide Chemical compound CCN(CC)C(=O)C=C OVHHHVAVHBHXAK-UHFFFAOYSA-N 0.000 claims 1
- 125000000565 sulfonamide group Chemical group 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea group Chemical group NC(=O)N XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23697300P | 2000-09-29 | 2000-09-29 | |
| US60/236,973 | 2000-09-29 | ||
| US28401701P | 2001-04-16 | 2001-04-16 | |
| US60/284,017 | 2001-04-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530047A Division JP2004513890A (ja) | 2000-09-29 | 2001-09-27 | フェンタニルの経皮デリバリのための組成物 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010015817A Division JP2010100650A (ja) | 2000-09-29 | 2010-01-27 | フェンタニルの経皮デリバリのための組成物 |
| JP2010279739A Division JP5425751B2 (ja) | 2000-09-29 | 2010-12-15 | フェンタニルの経皮デリバリのための組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009185061A JP2009185061A (ja) | 2009-08-20 |
| JP2009185061A5 true JP2009185061A5 (enExample) | 2010-03-18 |
| JP4976445B2 JP4976445B2 (ja) | 2012-07-18 |
Family
ID=26930280
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530047A Pending JP2004513890A (ja) | 2000-09-29 | 2001-09-27 | フェンタニルの経皮デリバリのための組成物 |
| JP2009115044A Expired - Lifetime JP4976445B2 (ja) | 2000-09-29 | 2009-05-11 | フェンタニルの経皮デリバリのための組成物 |
| JP2010015817A Withdrawn JP2010100650A (ja) | 2000-09-29 | 2010-01-27 | フェンタニルの経皮デリバリのための組成物 |
| JP2010279739A Expired - Lifetime JP5425751B2 (ja) | 2000-09-29 | 2010-12-15 | フェンタニルの経皮デリバリのための組成物 |
| JP2013200504A Withdrawn JP2013256536A (ja) | 2000-09-29 | 2013-09-26 | フェンタニルの経皮デリバリのための組成物 |
| JP2015247296A Expired - Lifetime JP6437908B2 (ja) | 2000-09-29 | 2015-12-18 | フェンタニルの経皮デリバリのための組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530047A Pending JP2004513890A (ja) | 2000-09-29 | 2001-09-27 | フェンタニルの経皮デリバリのための組成物 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010015817A Withdrawn JP2010100650A (ja) | 2000-09-29 | 2010-01-27 | フェンタニルの経皮デリバリのための組成物 |
| JP2010279739A Expired - Lifetime JP5425751B2 (ja) | 2000-09-29 | 2010-12-15 | フェンタニルの経皮デリバリのための組成物 |
| JP2013200504A Withdrawn JP2013256536A (ja) | 2000-09-29 | 2013-09-26 | フェンタニルの経皮デリバリのための組成物 |
| JP2015247296A Expired - Lifetime JP6437908B2 (ja) | 2000-09-29 | 2015-12-18 | フェンタニルの経皮デリバリのための組成物 |
Country Status (24)
| Country | Link |
|---|---|
| US (18) | US20020119187A1 (enExample) |
| EP (6) | EP1322299B1 (enExample) |
| JP (6) | JP2004513890A (enExample) |
| KR (1) | KR20030043978A (enExample) |
| CN (1) | CN100490805C (enExample) |
| AR (1) | AR037081A1 (enExample) |
| AT (1) | ATE449599T1 (enExample) |
| AU (2) | AU1531502A (enExample) |
| BR (1) | BR0114315A (enExample) |
| CA (1) | CA2423836C (enExample) |
| CY (1) | CY1118798T1 (enExample) |
| CZ (1) | CZ305119B6 (enExample) |
| DE (1) | DE60140616D1 (enExample) |
| DK (2) | DK2158905T3 (enExample) |
| EE (1) | EE05391B1 (enExample) |
| ES (2) | ES2407987T3 (enExample) |
| HU (1) | HUP0302926A3 (enExample) |
| IL (1) | IL154857A0 (enExample) |
| MX (1) | MXPA03002548A (enExample) |
| NO (1) | NO333525B1 (enExample) |
| NZ (1) | NZ524767A (enExample) |
| PL (1) | PL360708A1 (enExample) |
| PT (2) | PT2153828T (enExample) |
| WO (1) | WO2002026217A2 (enExample) |
Families Citing this family (88)
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| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| JP2004509222A (ja) * | 2000-09-19 | 2004-03-25 | ナショナル スターチ アンド ケミカル インベストメント ホールディング コーポレイション | 経皮薬物送達システムにおいて有用な非反応型接着剤 |
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| JP5354763B2 (ja) * | 2001-03-16 | 2013-11-27 | アルザ・コーポレーシヨン | フェンタニルを投与するための経皮的張り付け剤 |
| US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
| DE10141650C1 (de) * | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
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| WO2003090729A1 (en) * | 2002-04-23 | 2003-11-06 | Alza Corporation | Transdermal analgesic systems with reduced abuse potential |
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2001
- 2001-09-26 US US09/965,610 patent/US20020119187A1/en not_active Abandoned
- 2001-09-27 AU AU1531502A patent/AU1531502A/xx active Pending
- 2001-09-27 EP EP01983925A patent/EP1322299B1/en not_active Expired - Lifetime
- 2001-09-27 KR KR10-2003-7004485A patent/KR20030043978A/ko not_active Ceased
- 2001-09-27 WO PCT/US2001/031052 patent/WO2002026217A2/en not_active Ceased
- 2001-09-27 MX MXPA03002548A patent/MXPA03002548A/es not_active Application Discontinuation
- 2001-09-27 IL IL15485701A patent/IL154857A0/xx unknown
- 2001-09-27 EE EEP200300123A patent/EE05391B1/xx unknown
- 2001-09-27 AU AU2002215315A patent/AU2002215315C1/en not_active Expired
- 2001-09-27 DK DK09176390.4T patent/DK2158905T3/da active
- 2001-09-27 CN CNB018164722A patent/CN100490805C/zh not_active Expired - Lifetime
- 2001-09-27 PT PT91763987T patent/PT2153828T/pt unknown
- 2001-09-27 EP EP20090176388 patent/EP2153827A3/en not_active Ceased
- 2001-09-27 PT PT91763904T patent/PT2158905E/pt unknown
- 2001-09-27 BR BR0114315-8A patent/BR0114315A/pt active Search and Examination
- 2001-09-27 PL PL01360708A patent/PL360708A1/xx not_active Application Discontinuation
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- 2001-09-27 DE DE60140616T patent/DE60140616D1/de not_active Expired - Lifetime
- 2001-09-27 EP EP10181393A patent/EP2266547A1/en not_active Withdrawn
- 2001-09-27 JP JP2002530047A patent/JP2004513890A/ja active Pending
- 2001-09-27 EP EP09176398.7A patent/EP2153828B1/en not_active Revoked
- 2001-09-27 ES ES09176390T patent/ES2407987T3/es not_active Expired - Lifetime
- 2001-09-27 CZ CZ2003-890A patent/CZ305119B6/cs not_active IP Right Cessation
- 2001-09-27 EP EP09176390A patent/EP2158905B1/en not_active Revoked
- 2001-09-27 NZ NZ524767A patent/NZ524767A/xx not_active IP Right Cessation
- 2001-09-27 HU HU0302926A patent/HUP0302926A3/hu unknown
- 2001-09-27 AT AT01983925T patent/ATE449599T1/de active
- 2001-09-27 DK DK09176398.7T patent/DK2153828T3/en active
- 2001-09-27 EP EP20090176378 patent/EP2158904A3/en not_active Withdrawn
- 2001-09-27 ES ES09176398.7T patent/ES2621169T3/es not_active Expired - Lifetime
- 2001-10-01 AR ARP010104619A patent/AR037081A1/es not_active Application Discontinuation
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2003
- 2003-03-13 NO NO20031165A patent/NO333525B1/no not_active IP Right Cessation
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2006
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2010
- 2010-01-27 JP JP2010015817A patent/JP2010100650A/ja not_active Withdrawn
- 2010-06-22 US US12/820,280 patent/US20100255073A1/en not_active Abandoned
- 2010-08-06 US US12/851,808 patent/US20110038918A1/en not_active Abandoned
- 2010-12-15 JP JP2010279739A patent/JP5425751B2/ja not_active Expired - Lifetime
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2011
- 2011-10-18 US US13/275,498 patent/US20120269878A2/en not_active Abandoned
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2012
- 2012-11-08 US US13/672,057 patent/US20130064877A1/en not_active Abandoned
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2013
- 2013-07-09 US US13/937,365 patent/US20130295158A1/en not_active Abandoned
- 2013-09-26 JP JP2013200504A patent/JP2013256536A/ja not_active Withdrawn
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2014
- 2014-02-25 US US14/188,909 patent/US20140170206A1/en not_active Abandoned
- 2014-10-07 US US14/507,981 patent/US20150025480A1/en not_active Abandoned
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2015
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- 2015-12-18 JP JP2015247296A patent/JP6437908B2/ja not_active Expired - Lifetime
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2016
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2017
- 2017-03-24 CY CY20171100368T patent/CY1118798T1/el unknown
- 2017-06-30 US US15/638,576 patent/US20170296486A1/en not_active Abandoned
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2018
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2019
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2020
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2021
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