JP2009179634A5 - - Google Patents

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Publication number
JP2009179634A5
JP2009179634A5 JP2009115279A JP2009115279A JP2009179634A5 JP 2009179634 A5 JP2009179634 A5 JP 2009179634A5 JP 2009115279 A JP2009115279 A JP 2009115279A JP 2009115279 A JP2009115279 A JP 2009115279A JP 2009179634 A5 JP2009179634 A5 JP 2009179634A5
Authority
JP
Japan
Prior art keywords
escitalopram
salt
oxalate
base
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009115279A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009179634A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2009179634A publication Critical patent/JP2009179634A/ja
Publication of JP2009179634A5 publication Critical patent/JP2009179634A5/ja
Pending legal-status Critical Current

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JP2009115279A 2005-06-22 2009-05-12 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤 Pending JP2009179634A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200500912 2005-06-22

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2008517323A Division JP4906852B2 (ja) 2005-06-22 2006-06-22 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤

Publications (2)

Publication Number Publication Date
JP2009179634A JP2009179634A (ja) 2009-08-13
JP2009179634A5 true JP2009179634A5 (enExample) 2012-01-19

Family

ID=37546630

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2008517323A Active JP4906852B2 (ja) 2005-06-22 2006-06-22 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤
JP2008260742A Active JP4415056B2 (ja) 2005-06-22 2008-10-07 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤
JP2009115279A Pending JP2009179634A (ja) 2005-06-22 2009-05-12 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤
JP2009115280A Pending JP2009179635A (ja) 2005-06-22 2009-05-12 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤
JP2011255804A Active JP5731957B2 (ja) 2005-06-22 2011-11-24 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2008517323A Active JP4906852B2 (ja) 2005-06-22 2006-06-22 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤
JP2008260742A Active JP4415056B2 (ja) 2005-06-22 2008-10-07 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009115280A Pending JP2009179635A (ja) 2005-06-22 2009-05-12 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤
JP2011255804A Active JP5731957B2 (ja) 2005-06-22 2011-11-24 エスシタロプラムの結晶質塩基、およびエスシタロプラム塩基を含む口腔内分散性錠剤

Country Status (39)

Country Link
EP (3) EP2325177A1 (enExample)
JP (5) JP4906852B2 (enExample)
KR (5) KR101340815B1 (enExample)
CN (2) CN101928269A (enExample)
AR (2) AR055062A1 (enExample)
AT (3) ATE497500T1 (enExample)
AU (2) AU2006261452B2 (enExample)
BG (1) BG66086B1 (enExample)
BR (1) BRPI0612295A2 (enExample)
CA (2) CA2646780A1 (enExample)
CY (1) CY1112392T1 (enExample)
CZ (3) CZ300686B6 (enExample)
DE (2) DE112006001619T5 (enExample)
DK (3) DK1896439T4 (enExample)
EA (2) EA201001108A1 (enExample)
EE (1) EE00773U1 (enExample)
ES (2) ES2356838T5 (enExample)
FI (2) FI20077133L (enExample)
GB (2) GB2442160B (enExample)
HR (1) HRP20110093T4 (enExample)
HU (1) HUP0800135A3 (enExample)
IL (1) IL187454A0 (enExample)
IS (1) IS8705A (enExample)
LT (1) LT5550B (enExample)
LV (1) LV13677B (enExample)
MX (1) MX2007015328A (enExample)
MY (2) MY143252A (enExample)
NO (2) NO20080359L (enExample)
PL (2) PL1896439T5 (enExample)
PT (1) PT1896439E (enExample)
RS (1) RS51575B2 (enExample)
SG (1) SG169358A1 (enExample)
SI (1) SI1896439T2 (enExample)
SK (1) SK500402007A3 (enExample)
TR (2) TR200708792T1 (enExample)
TW (2) TWI358407B (enExample)
UA (1) UA86536C2 (enExample)
WO (1) WO2006136169A2 (enExample)
ZA (2) ZA200711066B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
EP2134325A2 (en) * 2007-03-01 2009-12-23 Aurobindo Pharma Limited Stable solid dosage forms of an antidepressant
HUE028897T2 (en) 2010-07-23 2017-01-30 H Lundbeck As A method of purifying pharmaceutically acceptable salts of escitalopram
CN103360353A (zh) * 2013-08-07 2013-10-23 中国药科大学 草酸艾司西酞普兰杂质的制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ (1s)−1−[3−(ジメチルアミノ)プロピル]−1−(4−フルオロフェニル)−1,3−ジヒドロイソベンゾフラン−5−カルボニトリル蓚酸塩の製造方法
JP6423133B1 (ja) * 2017-04-10 2018-11-14 東和薬品株式会社 エスシタロプラム医薬組成物
CN110711198B (zh) * 2018-07-12 2022-03-15 山东大学 D-甘露糖在制备抗抑郁药物中的应用
KR102331187B1 (ko) 2019-04-09 2021-11-26 주식회사 라이트팜텍 에스시탈로프람을 함유하는 안정성이 우수한 경구용 액제 조성물 및 그의 제조방법
EP4277661A1 (en) * 2021-01-18 2023-11-22 Anton Frenkel Pharmaceutical dosage form

Family Cites Families (39)

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GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
JPH05222041A (ja) * 1992-02-13 1993-08-31 Mitsubishi Gas Chem Co Inc アデニン誘導体の精製法
EP0743850B1 (en) * 1994-01-27 1999-10-06 The Board Of Regents Of The University Of Oklahoma Rapidly dissolving oral dosage form
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
EP0993524B1 (en) 1997-06-30 2002-11-20 Beloit Technologies, Inc. Method and apparatus for the high speed application of coating to a traveling paper web
SK283309B6 (sk) 1997-07-08 2003-05-02 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
DK1042310T3 (da) 1997-11-11 2002-12-02 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
JP2001226372A (ja) * 1999-12-06 2001-08-21 Sumika Fine Chemicals Co Ltd ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
AU2001294192A1 (en) * 2000-10-06 2002-04-22 Takeda Chemical Industries Ltd. Solid preparations
WO2002032403A1 (fr) * 2000-10-16 2002-04-25 Daiichi Pharmaceutical Co., Ltd. Compositions medicales pouvant se desintegrer rapidement dans la cavite buccale et leur procede de production
US7799342B2 (en) * 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
CA2360303C (en) * 2000-12-22 2003-08-12 Marco Villa Process for the preparation of pure citalopram
SK284418B6 (sk) * 2000-12-28 2005-04-01 H. Lundbeck A/S Spôsob výroby citalopramu
CZ20033267A3 (en) * 2001-05-01 2004-06-16 H. Lundbeck A/S The use of enantiomeric pure escitalopram
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
GB0113842D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
AR034612A1 (es) * 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
PT1522539E (pt) * 2001-07-31 2007-03-30 Lundbeck & Co As H Composição cristalina contendo escitalopram
IS7239A (is) * 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
FR2834889B1 (fr) * 2002-01-18 2004-04-02 Roquette Freres Forme pharmaceutique solide orodispersible
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
WO2003092659A1 (en) * 2002-05-03 2003-11-13 Skyepharma Canada Inc. Oral dosage forms comprising fenofibrate
MEP5808A (xx) 2002-12-23 2010-02-10 Lundbeck & Co As H Ecitalopram bromhidrat i postupak za njegovo pripremanje
CN1510024A (zh) * 2002-12-24 2004-07-07 北京德众万全药物技术开发有限公司 可用于制备西酞普兰(s)-对映异构体的新的化合物及其制备方法
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
AU2004238321B2 (en) * 2003-05-07 2009-08-27 Samyang Biopharmaceuticals Corporation Highly plastic granules for making fast melting tablets
ES2688193T3 (es) * 2003-10-15 2018-10-31 Fuji Chemical Industry Co., Ltd. Comprimido de disgregación rápida en la cavidad oral
WO2005049596A1 (en) * 2003-11-20 2005-06-02 Natco Pharma Limited A process for the preparation of high purity escitalopram
HU227491B1 (en) * 2003-11-25 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Tablet containing citalopram hydrogen bromide
NZ549100A (en) * 2004-03-05 2010-02-26 Lundbeck & Co As H Crystalline composition containing escitalopram oxalate
EP1877394A1 (en) * 2005-04-04 2008-01-16 Jubilant Organosys Limited Process for the preparation of escitalopram or its acid addition salts

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