JP2009173664A5 - - Google Patents

Download PDF

Info

Publication number
JP2009173664A5
JP2009173664A5 JP2009063830A JP2009063830A JP2009173664A5 JP 2009173664 A5 JP2009173664 A5 JP 2009173664A5 JP 2009063830 A JP2009063830 A JP 2009063830A JP 2009063830 A JP2009063830 A JP 2009063830A JP 2009173664 A5 JP2009173664 A5 JP 2009173664A5
Authority
JP
Japan
Prior art keywords
pharmaceutical kit
kit according
vaccine
intradermal
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009063830A
Other languages
English (en)
Other versions
JP2009173664A (ja
JP5960380B2 (ja
Filing date
Publication date
Priority claimed from GB0104538A external-priority patent/GB0104538D0/en
Priority claimed from GB0107511A external-priority patent/GB0107511D0/en
Priority claimed from GB0108365A external-priority patent/GB0108365D0/en
Application filed filed Critical
Publication of JP2009173664A publication Critical patent/JP2009173664A/ja
Publication of JP2009173664A5 publication Critical patent/JP2009173664A5/ja
Application granted granted Critical
Publication of JP5960380B2 publication Critical patent/JP5960380B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Claims (4)

  1. （i）皮膚の表面下約１．０ｍｍ〜２．０ｍｍの位置に投与するように構成された皮内短針送達デバイス、および、
    （ii）3種以上のインフルエンザ株を含む非生インフルエンザワクチン
    を含む医薬用キット。
  2. （i）皮膚の表面下１．０ｍｍ〜２．０ｍｍの位置に投与するように構成された皮内短針送達デバイス、および、
    （ii）三価非生インフルエンザワクチン
    を含む、請求項１に記載の医薬用キット。
  3. ワクチンの容量が０．０５〜０．２ｍｌである、請求項１又は２記載の医薬用キット。
  4. ワクチンがすでに充填された形で前記デバイスが供給される、請求項１又は２に記載の医薬用キット。
JP2009063830A 2001-02-23 2009-03-17 新規なワクチン Expired - Fee Related JP5960380B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB0104538.4 2001-02-23
GB0104538A GB0104538D0 (en) 2001-02-23 2001-02-23 Novel Vaccine
GB0107511.8 2001-03-26
GB0107511A GB0107511D0 (en) 2001-03-26 2001-03-26 Novel vaccine
GB0108365A GB0108365D0 (en) 2001-04-03 2001-04-03 Novel compounds
GB0108365.8 2001-04-03

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2002573043A Division JP5208347B2 (ja) 2001-02-23 2002-02-21 新規なワクチン

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011201447A Division JP6076592B2 (ja) 2001-02-23 2011-09-15 新規なワクチン

Publications (3)

Publication Number Publication Date
JP2009173664A JP2009173664A (ja) 2009-08-06
JP2009173664A5 true JP2009173664A5 (ja) 2011-11-04
JP5960380B2 JP5960380B2 (ja) 2016-08-02

Family

ID=27256080

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2002573043A Expired - Fee Related JP5208347B2 (ja) 2001-02-23 2002-02-21 新規なワクチン
JP2009063830A Expired - Fee Related JP5960380B2 (ja) 2001-02-23 2009-03-17 新規なワクチン
JP2011201447A Expired - Fee Related JP6076592B2 (ja) 2001-02-23 2011-09-15 新規なワクチン
JP2015084294A Expired - Fee Related JP6211555B2 (ja) 2001-02-23 2015-04-16 新規なワクチン
JP2017134258A Pending JP2017186367A (ja) 2001-02-23 2017-07-10 新規なワクチン

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2002573043A Expired - Fee Related JP5208347B2 (ja) 2001-02-23 2002-02-21 新規なワクチン

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2011201447A Expired - Fee Related JP6076592B2 (ja) 2001-02-23 2011-09-15 新規なワクチン
JP2015084294A Expired - Fee Related JP6211555B2 (ja) 2001-02-23 2015-04-16 新規なワクチン
JP2017134258A Pending JP2017186367A (ja) 2001-02-23 2017-07-10 新規なワクチン

Country Status (11)

Country Link
US (4) US20040071734A1 (ja)
EP (3) EP2281573A3 (ja)
JP (5) JP5208347B2 (ja)
AT (1) ATE503493T1 (ja)
AU (1) AU2002254901A1 (ja)
CA (1) CA2438942A1 (ja)
CY (1) CY1111553T1 (ja)
DE (3) DE60239594D1 (ja)
DK (1) DK1361890T3 (ja)
PT (1) PT1361890E (ja)
WO (1) WO2002074336A2 (ja)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1214054B1 (en) * 1999-09-24 2007-10-31 GlaxoSmithKline Biologicals S.A. Intranasal influenza virus vaccine
DK1361890T3 (da) * 2001-02-23 2011-06-27 Glaxosmithkline Biolog Sa Influenzavaccineformuleringer til intradermal indgift
US20040096463A1 (en) * 2001-02-23 2004-05-20 Nathalie Garcon Novel vaccine
WO2002087494A2 (en) * 2001-04-27 2002-11-07 Glaxosmithkline Biologicals, Sa Novel vaccine
CA2451816A1 (en) * 2001-06-29 2003-01-09 Becton, Dickinson And Company Intradermal delivery of vaccines and gene therapeutic agents via microcannula
US20060110406A1 (en) 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
KR101360300B1 (ko) 2003-02-25 2014-02-13 메디뮨 엘엘씨 인플루엔자 백신 조성물의 제조 방법
US7588774B2 (en) 2003-05-12 2009-09-15 Becton, Dickinson And Company Molecules enhancing dermal delivery of influenza vaccines
US20050123550A1 (en) * 2003-05-12 2005-06-09 Laurent Philippe E. Molecules enhancing dermal delivery of influenza vaccines
US7566458B2 (en) * 2003-06-16 2009-07-28 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
US20080254065A1 (en) 2004-03-09 2008-10-16 Chiron Corporation Influenza Virus Vaccines
EP1796719B1 (en) * 2004-10-06 2014-12-03 MedImmune, LLC Refrigerator-temperature stable influenza vaccine compositions
JP2008519042A (ja) * 2004-11-03 2008-06-05 ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド インフルエンザワクチン接種
ES2527503T3 (es) * 2005-03-08 2015-01-26 Medimmune, Llc Virus influenza reordenantes
AR053833A1 (es) * 2005-03-23 2007-05-23 Glaxosmithkline Biolog Sa Composicion inmunogenetica
JP4828189B2 (ja) * 2005-09-14 2011-11-30 雅美 森山 分泌型ＩｇＡ及びＩｇＧ抗体誘導剤
NZ567817A (en) 2005-11-01 2012-01-12 Novartis Vaccines & Diagnostic Cell-derived viral vaccines with low levels of residual cell DNA by beta-propiolactone treatment
EP1951301A2 (en) 2005-11-04 2008-08-06 Novartis Vaccines and Diagnostics S.r.l. Emulsions with free aqueous-phase surfactant for adjuvanting split influenza vaccines
CN102755645A (zh) 2005-11-04 2012-10-31 诺华疫苗和诊断有限公司 佐剂配制的包含细胞因子诱导剂的流感疫苗
PL1945252T3 (pl) 2005-11-04 2013-11-29 Seqirus Uk Ltd Szczepionki zawierające oczyszczone antygeny powierzchniowe otrzymane z wirusów grypy hodowanych w hodowli komórkowej i skwalen jako adiuwant
EP1951302A2 (en) 2005-11-04 2008-08-06 Novartis Vaccines and Diagnostics S.r.l. Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant
EP1951299B1 (en) 2005-11-04 2012-01-04 Novartis Vaccines and Diagnostics S.r.l. Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
EP3753574A1 (en) 2006-01-27 2020-12-23 Seqirus UK Limited Influenza vaccines containing hemagglutinin and matrix proteins
US20100068223A1 (en) * 2006-03-24 2010-03-18 Hanno Scheffczik Storage of Influenza Vaccines Without Refrigeration
KR101696727B1 (ko) 2006-07-17 2017-01-16 글락소스미스클라인 바이오로지칼즈 에스.에이. 인플루엔자 백신
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
KR20090057015A (ko) 2006-09-11 2009-06-03 노파르티스 아게 난을 사용하지 않는 인플루엔자 바이러스 백신의 제조
US20080124355A1 (en) 2006-09-22 2008-05-29 David Gordon Bermudes Live bacterial vaccines for viral infection prophylaxis or treatment
CN101553252A (zh) 2006-12-06 2009-10-07 诺华有限公司 包含来自于四株流感病毒的抗原的疫苗
TW200908994A (en) 2007-04-20 2009-03-01 Glaxosmithkline Biolog Sa Vaccine
MX2009013118A (es) * 2007-06-14 2010-03-04 Crucell Switzerland Ag Vacuna intradermica contra la influenza.
EP2484377A1 (en) 2007-06-27 2012-08-08 Novartis AG Low-additive influenza vaccines
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
NZ586439A (en) 2007-12-24 2012-10-26 Novartis Ag Method for peforming an immunodiffusion assay (SRID) for influenza hemagglutinin antigen based on desorbing the antigen from the aluminium adjuvant salt
US8506966B2 (en) 2008-02-22 2013-08-13 Novartis Ag Adjuvanted influenza vaccines for pediatric use
EA201071086A1 (ru) 2008-03-18 2011-04-29 Новартис Аг Усовершенствованный способ получения вакцинных антигенов вируса гриппа
WO2010006144A2 (en) * 2008-07-11 2010-01-14 Medlmmune, Llc. Influenza hemagglutinin and neuraminidase variants
JP5182753B2 (ja) * 2008-09-01 2013-04-17 富士フイルム株式会社 インフルエンザ罹患リスクの予測方法
CA2741961A1 (en) 2008-11-05 2010-05-14 Glaxosmithkline Biologicals S.A. Novel method
EA201500910A1 (ru) 2009-02-10 2016-04-29 Новартис Аг Вакцины против гриппа со сниженным количеством сквалена
US20120093860A1 (en) 2009-02-10 2012-04-19 Novartis Ag Influenza vaccines with increased amounts of h3 antigen
WO2010092476A1 (en) 2009-02-10 2010-08-19 Novartis Ag Influenza vaccine regimens for pandemic-associated strains
KR20120027276A (ko) 2009-04-27 2012-03-21 노파르티스 아게 인플루엔자를 예방하기 위한 면역증강된 백신
EA021009B1 (ru) 2009-05-21 2015-03-31 Новартис Аг ОБРАТНАЯ ГЕНЕТИКА С ИСПОЛЬЗОВАНИЕМ НЕЭНДОГЕННЫХ ПРОМОТОРОВ pol I
CN104862335A (zh) 2009-07-31 2015-08-26 诺华股份有限公司 反向遗传系统
US20120237536A1 (en) 2009-09-10 2012-09-20 Novartis Combination vaccines against respiratory tract diseases
WO2011048560A1 (en) 2009-10-20 2011-04-28 Novartis Ag Improved reverse genetics methods for virus rescue
GB0918830D0 (en) * 2009-10-27 2009-12-09 Glaxosmithkline Biolog Niederl Process
US9426989B2 (en) 2010-05-06 2016-08-30 Novartis Ag Organic peroxide compounds for microorganism inactivation
US8945904B2 (en) 2010-05-21 2015-02-03 Novartis Ag Influenza virus reassortment
JP5976639B2 (ja) 2010-06-01 2016-08-23 ノバルティス アーゲー インフルエンザワクチン抗原の濃縮および凍結乾燥
CA2801149A1 (en) 2010-06-01 2011-12-08 Novartis Ag Concentration of vaccine antigens without lyophilization
WO2011154976A2 (en) 2010-06-08 2011-12-15 Panacea Biotec Limited Improved influenza vaccine
ES2531577T3 (es) 2010-08-20 2015-03-17 Novartis Ag Conjuntos de agujas para la administración de vacuna soluble contra la gripe
GB201216121D0 (en) 2012-09-10 2012-10-24 Novartis Ag Sample quantification by disc centrifugation
JP2014532620A (ja) 2011-10-20 2014-12-08 ノバルティス アーゲー 小児の初回免疫のためのアジュバント添加インフルエンザｂウイルスワクチン
GB201120000D0 (en) * 2011-11-20 2012-01-04 Glaxosmithkline Biolog Sa Vaccine
CA2813723A1 (en) 2012-03-02 2013-09-02 Novartis Ag Influenza virus reassortment
CN104159608A (zh) 2012-03-06 2014-11-19 克鲁塞尔荷兰公司 针对流感的改善的疫苗接种
EP2855701A1 (en) 2012-06-04 2015-04-08 Novartis AG Improved safety testing
GB201218195D0 (en) 2012-10-10 2012-11-21 Istituto Zooprofilattico Sperimentale Delle Venezie Composition
MX2015006927A (es) 2012-12-03 2016-02-05 Novartis Ag Redistribucion de virus de la influenza.
UY34506A (es) * 2012-12-10 2014-06-30 Fernando Amaury Ferreira Chiesa Adyuvante de vacunación, preparación y vacunas que lo contienen
US20140193484A1 (en) 2013-01-10 2014-07-10 Sylvie Carine Bertholet Girardin Influenza virus immunogenic compositions and uses thereof
US10232031B2 (en) 2013-03-13 2019-03-19 Seqirus UK Limited Influenza virus reassortment
MX2015015428A (es) 2013-05-10 2016-07-18 Novartis Ag Eliminacion de riesgo de narcolepsia en vacunas contra influenza.
DE202013005130U1 (de) 2013-06-05 2013-09-10 Novartis Ag Influenza Virus Reassortierung
DE202013005100U1 (de) 2013-06-05 2013-08-26 Novartis Ag Influenza Virus Reassortierung
CN105722976A (zh) 2013-06-06 2016-06-29 诺华股份有限公司 流感病毒重配
WO2015071177A1 (en) 2013-11-15 2015-05-21 Novartis Ag Removal of residual cell culture impurities
WO2016008039A1 (en) 2014-07-14 2016-01-21 Novicol International Holding Inc. Microbicidal composition comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
JP6719388B2 (ja) * 2014-12-25 2020-07-08 テルモ株式会社 皮内投与インフルエンザワクチン組成物
US11013795B2 (en) 2015-06-26 2021-05-25 Seqirus UK Limited Antigenically matched influenza vaccines
AU2016290603B2 (en) 2015-07-07 2022-06-02 Seqirus UK Limited Influenza potency assays
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
WO2020174288A1 (en) 2019-02-25 2020-09-03 Seqirus UK Limited Adjuvanted multivalent influenza vaccines
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
MX2022005513A (es) 2019-11-07 2022-06-08 Seqirus Uk Ltd Composiciones y metodos para producir una vacuna viral con tama?o de particula reducido.
EP4061930A1 (en) 2019-11-18 2022-09-28 Seqirus Pty Ltd Method for producing reassortant influenza viruses
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5520A (en) 1848-04-18 Oegan-pipb
US639A (en) 1838-03-17 of boston
US1274081A (en) * 1917-05-10 1918-07-30 Herman A Metz Hypodermic needle.
US1436707A (en) * 1921-08-10 1922-11-28 American Platinum Works Adjustable and safety regulating device for hypodermic needles
FR1001668A (fr) * 1946-06-17 1952-02-26 Seringue pour anesthésie tronculaire du maxillaire inférieur
US2559474A (en) * 1950-03-09 1951-07-03 Sonco Inc Hypodermic and spinal syringe
FR1072399A (fr) * 1961-01-07 1954-09-13 Injecteur intra-dermique
US3400715A (en) * 1966-01-04 1968-09-10 Halvard J. Pederson Attachment for injection apparatus
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
JPS52132590A (en) 1976-04-27 1977-11-07 Haabaato Bogeruman Jiyosefu Injector
US4270537A (en) 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
JPS5695058A (en) 1979-12-10 1981-08-01 Toyo Jozo Kk Microosyringe
DD155875A1 (de) 1980-12-31 1982-07-14 Willy Nordheim Verfahren zur herstellung eines ballaststoffarmen inaktivierten influenzaimpfstoffes
US4436727A (en) 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
SE8205892D0 (sv) 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
JPS6153226A (ja) * 1984-08-24 1986-03-17 Chemo Sero Therapeut Res Inst 単純ヘルペスサブユニツトワクチンの精製方法
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
JPH0688911B2 (ja) * 1985-06-06 1994-11-09 国立予防衛生研究所長 インフルエンザワクチン及びその製造方法
US4886499A (en) * 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
GB8704027D0 (en) 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
CA1331443C (en) 1987-05-29 1994-08-16 Charlotte A. Kensil Saponin adjuvant
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US6056716A (en) * 1987-06-08 2000-05-02 D'antonio Consultants International Inc. Hypodermic fluid dispenser
US5569190A (en) * 1987-06-08 1996-10-29 D'antonio; Nicholas F. Hypodermic fluid dispenser
US5080648A (en) * 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
GB2206794A (en) 1987-07-14 1989-01-18 Richard Kiteley Power Syringe
DE3734306A1 (de) 1987-10-10 1989-04-27 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer fliessfaehige medien
US5195526A (en) * 1988-03-11 1993-03-23 Michelson Gary K Spinal marker needle
US5339163A (en) 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
FR2638359A1 (fr) 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
DE4005528C2 (de) 1990-02-22 1998-01-15 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
US5279581A (en) 1990-05-09 1994-01-18 Firth John R Disposable self-shielding hypodermic syringe
US5190521A (en) 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
TW279133B (ja) * 1990-12-13 1996-06-21 Elan Med Tech
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
DE4127887C1 (en) 1991-08-22 1993-01-28 Manfred Prof. Dr. 8520 Erlangen De Herbst Subcutaneous medicine delivery device preventing needle from exceeding required depth - comprises tube attached with needle free to move on wedge shaped needle holder with needle penetration holes of different depth
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
SE9102652D0 (sv) 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
CA2085827C (en) 1991-12-23 2003-10-14 Lucas A. T. Hilgers Adjuvant composition containing synthetic hydrophobic lipopolysaccharide
US5328483A (en) 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
IL101720A (en) * 1992-04-29 1998-09-24 Mali Tech Ltd Needle for syringe or the like
DE69327599T2 (de) 1992-06-25 2000-08-10 Smithkline Beecham Biolog Adjuvantien enthaltende Impfstoffzusammensetzung
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
WO1994019013A1 (en) * 1993-02-19 1994-09-01 Smithkline Beecham Corporation Influenza vaccine compositions containing 3-o-deacylated monophosphoryl lipid a
CN1124013A (zh) * 1993-02-19 1996-06-05 史密丝克莱恩比彻姆公司 含3-邻位-脱酰基的单磷酰基脂质a的流感疫苗组合物
ATE204762T1 (de) 1993-03-23 2001-09-15 Smithkline Beecham Biolog 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen
IE68890B1 (en) * 1993-04-08 1996-07-24 Elan Med Tech Intradermal delivery device
ES2370937T3 (es) * 1993-09-13 2011-12-23 Protein Sciences Corporation Un método para producir vacunas antigripales polivalentes a base de hemaglutinina.
US6485729B1 (en) * 1993-09-13 2002-11-26 Protein Sciences Corporation Neuraminidase-supplemented compositions
CA2171563A1 (en) 1993-09-14 1995-03-23 Eric Le Cheminant Injection device
US5997501A (en) * 1993-11-18 1999-12-07 Elan Corporation, Plc Intradermal drug delivery device
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
WO1995024176A1 (en) 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
JPH07299143A (ja) 1994-05-09 1995-11-14 Kenji Tsubota 医科用注射針
AUPM873294A0 (en) 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
GB9620795D0 (en) * 1996-10-05 1996-11-20 Smithkline Beecham Plc Vaccines
UA56132C2 (uk) * 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US7223739B1 (en) * 1995-06-07 2007-05-29 Powderject Vaccines, Inc. Adjuvanted genetic vaccines
SE9502285D0 (sv) 1995-06-22 1995-06-22 Pharmacia Ab Improvements related to injections
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
BR9705023A (pt) * 1996-10-12 1998-12-01 Luk Getriebe Systeme Gmbh Veículo automotor
US5776107A (en) * 1996-12-31 1998-07-07 Delab Injection device
EP0971739B1 (en) 1997-04-01 2004-10-06 Corixa Corporation Aqueous immunologic adjuvant compositions of monophosphoryl lipid a
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
US5944700A (en) 1997-09-26 1999-08-31 Becton, Dickinson And Company Adjustable injection length pen needle
US6482176B1 (en) 1997-11-27 2002-11-19 Disetronic Licensing Ag Method and device for controlling the introduction depth of an injection needle
IT1298087B1 (it) * 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
JP4118399B2 (ja) 1998-07-21 2008-07-16 テルモ株式会社 注射針用穿刺調整具およびそれを備えた注射針組立体
US6309374B1 (en) 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
US6159472A (en) 1998-11-16 2000-12-12 Akzo Nobel N.V. Intradermal Avian immunization with inactivated vaccines
AR022963A1 (es) 1999-03-19 2002-09-04 Smithkline Beecham Biolog Vacuna
EP1187653B1 (en) 1999-06-04 2010-03-31 Georgia Tech Research Corporation Devices for enhanced microneedle penetration of biological barriers
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
EP1214054B1 (en) 1999-09-24 2007-10-31 GlaxoSmithKline Biologicals S.A. Intranasal influenza virus vaccine
CN1399539A (zh) * 1999-09-24 2003-02-26 史密丝克莱恩比彻姆生物有限公司 含有聚氧乙烯烷基醚或聚氧乙烯烷基酯以及至少一种非离子表面活性剂的佐剂
US6569143B2 (en) * 1999-10-14 2003-05-27 Becton, Dickinson And Company Method of intradermally injecting substances
US6776776B2 (en) * 1999-10-14 2004-08-17 Becton, Dickinson And Company Prefillable intradermal delivery device
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
US20020193740A1 (en) * 1999-10-14 2002-12-19 Alchas Paul G. Method of intradermally injecting substances
US6569123B2 (en) * 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US6843781B2 (en) * 1999-10-14 2005-01-18 Becton, Dickinson And Company Intradermal needle
US6494865B1 (en) * 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
DE19950530A1 (de) 1999-10-20 2001-06-13 Frank Neveling Spritze zur intrakutanen Injektion
DK1361890T3 (da) * 2001-02-23 2011-06-27 Glaxosmithkline Biolog Sa Influenzavaccineformuleringer til intradermal indgift
US20040096463A1 (en) * 2001-02-23 2004-05-20 Nathalie Garcon Novel vaccine
GB0109297D0 (en) * 2001-04-12 2001-05-30 Glaxosmithkline Biolog Sa Vaccine
WO2002087494A2 (en) * 2001-04-27 2002-11-07 Glaxosmithkline Biologicals, Sa Novel vaccine
CA2451816A1 (en) * 2001-06-29 2003-01-09 Becton, Dickinson And Company Intradermal delivery of vaccines and gene therapeutic agents via microcannula

Similar Documents

Publication Publication Date Title
JP2009173664A5 (ja)
JP2013014622A5 (ja)
JP2013542247A5 (ja)
JP2016501828A5 (ja)
MX339734B (es) Implemento para cuidado oral.
JP2012500090A5 (ja)
JP2013506466A5 (ja)
JP2011136997A5 (ja)
AR083361A1 (es) Forma de dosificacion de rapida disolucion de vacuna oral utilizando almidon
JP2015525757A5 (ja)
ES2445846R1 (es) Una composición de combinación farmacéutica y su uso para preparar un medicamento destinado al tatamiento de la diabetes de tipo l y los trastornos metabólicos
TWD159359S (zh) 藥物輸送裝置之部分
NI201000173A (es) Uso de dronedarona o una sal aceptable farmacéuticamente de ésta, para la preparación de un medicamento para regular el nivel de potasio en la sangre.
CL2013002996A1 (es) Uso de aclidinio o sus sales o cualquiera de sus estereoisomeros o mezcla de estereoisomeros, o una sal farmeceuticamente aceptable o solvato del mismo para la preparacion de un medicemnto util en mejorar la calidad del sueño en enfermos respiratorios.
TWD159760S (zh) 馬克杯
HK1150340A1 (en) The use of a traditional chinese medicine composition in the preparation of anti-influenza virus drugs
ES2485065A1 (es) Dispositivo para endodoncia mediante irrigación continua ultrasónica.
JP2016502995A5 (ja)
HK1150338A1 (en) The use of a traditional chinese medicine composition in the preparation of anti-influenza virus drugs
AR094063A1 (es) Uso de aclidinio, composicion farmaceutica y metodo para mejorar la actividad fisica en pacientes respiratorios
JP2014506563A5 (ja)
NZ580603A (en) Intradermal influenza vaccine
JP2013147480A5 (ja)
EA201590732A1 (ru) Диспергируемая таблетка
CN202061079U (zh) 斜底面安瓿