JP2009002816A - 分注処理装置 - Google Patents
分注処理装置 Download PDFInfo
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- JP2009002816A JP2009002816A JP2007164499A JP2007164499A JP2009002816A JP 2009002816 A JP2009002816 A JP 2009002816A JP 2007164499 A JP2007164499 A JP 2007164499A JP 2007164499 A JP2007164499 A JP 2007164499A JP 2009002816 A JP2009002816 A JP 2009002816A
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- 230000007246 mechanism Effects 0.000 claims description 10
- 238000001514 detection method Methods 0.000 claims description 4
- 239000007788 liquid Substances 0.000 abstract description 11
- 210000002700 urine Anatomy 0.000 abstract description 3
- 210000004369 blood Anatomy 0.000 abstract description 2
- 239000008280 blood Substances 0.000 abstract description 2
- 238000000926 separation method Methods 0.000 abstract 1
- 239000002699 waste material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 description 18
- 230000008569 process Effects 0.000 description 13
- 210000002966 serum Anatomy 0.000 description 10
- 230000032258 transport Effects 0.000 description 7
- 238000010586 diagram Methods 0.000 description 4
- 208000007536 Thrombosis Diseases 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000007723 transport mechanism Effects 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
- G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots
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- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
【解決手段】検査のために採取した血液や尿などの検体を吸引中に分離剤などによる詰りを検出した際に分注ヘッドをノズルチップの先端が液面から出ない程度に上昇させて詰りを解除させ、残圧によって吸引した後、さらに一定量追加吸引することによって検体残量を減らすことにより達成できる。
【効果】吸引処理において親検体残量を減らすことによって検体を無駄なく吸引する分注処理装置を提供する。
【選択図】図2
Description
2 ノズルチップ
3 親検体容器
4 検体容器搬送用ラック
10 血清
11 分離剤
12 血餅
Claims (6)
- 試料を吸引するノズルと、該ノズルを上下動させるノズル上下動機構と、該ノズルの詰りを検出するノズル詰り検出機構と、該ノズルに試料を吸引するように圧力を発生させる圧力発生機構を備えた分注処理装置において、
試料を吸引中に前記ノズル詰り検出機構がノズル詰りを検出した場合、詰りを検出した位置から該ノズルを所定量上昇するように前記ノズル上下動機構を動作させ、更に追加の吸引を行うように前記圧力発生機構を制御する制御機構を備えたことを特徴とする分注処理装置。 - 請求項1記載の分注処理装置において、
前記ノズルの上昇量を設定する設定機構を備えたことを特徴とする分注処理装置。 - 請求項1記載の分注処理装置において、
前記ノズルの所定量上昇によっても該ノズルの詰りが解除されない場合、所定量の吐出動作を行い、ノズル内に吸引済みの検体を子検体容器に吐出するように前記制御手段により制御することを特徴とする分注処理装置。 - 請求項1記載の分注処理装置において、
前記追加の吸引における追加吸引量は、詰り発生までの吸引量に基づき算出することを特徴とする分注処理装置。 - 請求項4記載の分注処理装置において、
前記追加吸引量は、エアを吸引しない範囲で可変設定可能とすることを特徴とする分注処理装置。 - 請求項5記載の分注処理装置において、
前記追加吸引量は、詰り発生までの吸引量に基づき算出した吸引量、又はエアを吸引しない範囲で可変設定した量の少ない方の量とすることを特徴とする分注処理装置。
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007164499A JP4982266B2 (ja) | 2007-06-22 | 2007-06-22 | 分注処理装置 |
EP08010925.9A EP2006689B1 (en) | 2007-06-22 | 2008-06-16 | Sample dispensing apparatus and method |
CN2008101286123A CN101329358B (zh) | 2007-06-22 | 2008-06-19 | 检体分注处理装置 |
US12/143,339 US8221702B2 (en) | 2007-06-22 | 2008-06-20 | Sample dispensing apparatus and method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007164499A JP4982266B2 (ja) | 2007-06-22 | 2007-06-22 | 分注処理装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009002816A true JP2009002816A (ja) | 2009-01-08 |
JP4982266B2 JP4982266B2 (ja) | 2012-07-25 |
Family
ID=39811549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007164499A Active JP4982266B2 (ja) | 2007-06-22 | 2007-06-22 | 分注処理装置 |
Country Status (4)
Country | Link |
---|---|
US (1) | US8221702B2 (ja) |
EP (1) | EP2006689B1 (ja) |
JP (1) | JP4982266B2 (ja) |
CN (1) | CN101329358B (ja) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008298494A (ja) * | 2007-05-30 | 2008-12-11 | Hitachi High-Technologies Corp | 分注装置 |
JP2012018126A (ja) * | 2010-07-09 | 2012-01-26 | Shimadzu Corp | オートサンプラ |
JP2012163562A (ja) * | 2011-02-07 | 2012-08-30 | Ortho-Clinical Diagnostics Inc | 測定圧力を用いた遠心分離血液の状態の判定 |
JP2016197106A (ja) * | 2011-01-21 | 2016-11-24 | セラノス, インコーポレイテッド | 試料使用の極大化のためのシステム及び方法 |
US10634667B2 (en) | 2007-10-02 | 2020-04-28 | Theranos Ip Company, Llc | Modular point-of-care devices, systems, and uses thereof |
JP2020128904A (ja) * | 2019-02-08 | 2020-08-27 | 株式会社島津製作所 | マイクロチップ電気泳動装置及びマイクロチップ電気泳動方法 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8545757B2 (en) * | 2009-01-30 | 2013-10-01 | Hitachi High-Technologies Corporation | Automatic analyzer and sample treatment apparatus |
JP5850625B2 (ja) * | 2011-03-02 | 2016-02-03 | シスメックス株式会社 | 分析装置及び位置確認方法 |
JP2013007579A (ja) * | 2011-06-22 | 2013-01-10 | Seiko Epson Corp | 分注方法 |
JP2013076674A (ja) * | 2011-09-30 | 2013-04-25 | Fujifilm Corp | 分注装置および吸引ノズル位置制御方法 |
CN103245774A (zh) * | 2012-02-07 | 2013-08-14 | 奥索临床诊断有限公司 | 使用测定压力确定离心血液中的状况 |
JP2013255447A (ja) * | 2012-06-12 | 2013-12-26 | Nippon Koden Corp | 細胞単離装置 |
JP6018828B2 (ja) * | 2012-07-27 | 2016-11-02 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
JP2014119387A (ja) * | 2012-12-18 | 2014-06-30 | Sony Corp | 分注装置、分析装置及び分注装置の制御方法 |
CN106596185B (zh) * | 2016-12-08 | 2019-06-04 | 辽宁石油化工大学 | 小型容器不同空间位置油品取样装置及方法 |
CN110780085B (zh) * | 2019-11-04 | 2021-03-09 | 苏州长光华医生物医学工程有限公司 | 一种全自动化学发光免疫分析仪的加样方法 |
EP3896460A1 (en) * | 2020-04-17 | 2021-10-20 | bioMérieux | Automatic sampling method for handling whole blood |
Citations (5)
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JPH0727679A (ja) * | 1993-06-24 | 1995-01-31 | Aloka Co Ltd | 全量抜取り分注方法及びその装置 |
JPH11264830A (ja) * | 1998-03-18 | 1999-09-28 | Olympus Optical Co Ltd | 自動分注装置 |
JP2007040932A (ja) * | 2005-08-05 | 2007-02-15 | Hitachi High-Technologies Corp | 検体分注処理装置 |
US20070143063A1 (en) * | 2005-12-19 | 2007-06-21 | Michael Kaplit | Method for ascertaining interferants in small liquid samples in an automated clinical analyzer |
JP2008298494A (ja) * | 2007-05-30 | 2008-12-11 | Hitachi High-Technologies Corp | 分注装置 |
Family Cites Families (7)
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JPS6264912A (ja) * | 1985-09-17 | 1987-03-24 | Minoru Atake | 分注方式 |
US5540081A (en) * | 1993-08-31 | 1996-07-30 | Abbott Laboratories | Pipetting apparatus with clot detection |
JPH08338849A (ja) * | 1995-04-11 | 1996-12-24 | Precision Syst Sci Kk | 液体の吸引判別方法およびこの方法により駆動制御される分注装置 |
JP3410018B2 (ja) | 1998-04-20 | 2003-05-26 | 株式会社日立製作所 | 検体分注装置及び検体処理システム |
US6022747A (en) * | 1998-07-10 | 2000-02-08 | Bayer Corporation | Blood clot detector |
JP4102863B2 (ja) * | 2003-02-14 | 2008-06-18 | 株式会社スタックシステム | 分注機及び分注装置 |
EP1882951B1 (en) * | 2005-05-19 | 2017-09-27 | Universal Bio Research Co., Ltd. | Method of detecting dispensed quantity, and liquid suction monitoring dispensing apparatus |
-
2007
- 2007-06-22 JP JP2007164499A patent/JP4982266B2/ja active Active
-
2008
- 2008-06-16 EP EP08010925.9A patent/EP2006689B1/en active Active
- 2008-06-19 CN CN2008101286123A patent/CN101329358B/zh active Active
- 2008-06-20 US US12/143,339 patent/US8221702B2/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH0727679A (ja) * | 1993-06-24 | 1995-01-31 | Aloka Co Ltd | 全量抜取り分注方法及びその装置 |
JPH11264830A (ja) * | 1998-03-18 | 1999-09-28 | Olympus Optical Co Ltd | 自動分注装置 |
JP2007040932A (ja) * | 2005-08-05 | 2007-02-15 | Hitachi High-Technologies Corp | 検体分注処理装置 |
US20070143063A1 (en) * | 2005-12-19 | 2007-06-21 | Michael Kaplit | Method for ascertaining interferants in small liquid samples in an automated clinical analyzer |
JP2008298494A (ja) * | 2007-05-30 | 2008-12-11 | Hitachi High-Technologies Corp | 分注装置 |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008298494A (ja) * | 2007-05-30 | 2008-12-11 | Hitachi High-Technologies Corp | 分注装置 |
US11061022B2 (en) | 2007-10-02 | 2021-07-13 | Labrador Diagnostics Llc | Modular point-of-care devices, systems, and uses thereof |
US11137391B2 (en) | 2007-10-02 | 2021-10-05 | Labrador Diagnostics Llc | Modular point-of-care devices, systems, and uses thereof |
US10900958B2 (en) | 2007-10-02 | 2021-01-26 | Labrador Diagnostics Llc | Modular point-of-care devices, systems, and uses thereof |
US10634667B2 (en) | 2007-10-02 | 2020-04-28 | Theranos Ip Company, Llc | Modular point-of-care devices, systems, and uses thereof |
US10670588B2 (en) | 2007-10-02 | 2020-06-02 | Theranos Ip Company, Llc | Modular point-of-care devices, systems, and uses thereof |
US11366106B2 (en) | 2007-10-02 | 2022-06-21 | Labrador Diagnostics Llc | Modular point-of-care devices, systems, and uses thereof |
US11092593B2 (en) | 2007-10-02 | 2021-08-17 | Labrador Diagnostics Llc | Modular point-of-care devices, systems, and uses thereof |
US11899010B2 (en) | 2007-10-02 | 2024-02-13 | Labrador Diagnostics Llc | Modular point-of-care devices, systems, and uses thereof |
US11199538B2 (en) | 2007-10-02 | 2021-12-14 | Labrador Diagnostics Llc | Modular point-of-care devices, systems, and uses thereof |
US11143647B2 (en) | 2007-10-02 | 2021-10-12 | Labrador Diagnostics, LLC | Modular point-of-care devices, systems, and uses thereof |
JP2012018126A (ja) * | 2010-07-09 | 2012-01-26 | Shimadzu Corp | オートサンプラ |
US11199489B2 (en) | 2011-01-20 | 2021-12-14 | Labrador Diagnostics Llc | Systems and methods for sample use maximization |
US10876956B2 (en) | 2011-01-21 | 2020-12-29 | Labrador Diagnostics Llc | Systems and methods for sample use maximization |
US10557786B2 (en) | 2011-01-21 | 2020-02-11 | Theranos Ip Company, Llc | Systems and methods for sample use maximization |
US11644410B2 (en) | 2011-01-21 | 2023-05-09 | Labrador Diagnostics Llc | Systems and methods for sample use maximization |
JP2016197106A (ja) * | 2011-01-21 | 2016-11-24 | セラノス, インコーポレイテッド | 試料使用の極大化のためのシステム及び方法 |
JP2012163562A (ja) * | 2011-02-07 | 2012-08-30 | Ortho-Clinical Diagnostics Inc | 測定圧力を用いた遠心分離血液の状態の判定 |
JP7120063B2 (ja) | 2019-02-08 | 2022-08-17 | 株式会社島津製作所 | マイクロチップ電気泳動装置及びマイクロチップ電気泳動方法 |
JP2020128904A (ja) * | 2019-02-08 | 2020-08-27 | 株式会社島津製作所 | マイクロチップ電気泳動装置及びマイクロチップ電気泳動方法 |
US11391696B2 (en) | 2019-02-08 | 2022-07-19 | Shimadzu Corporation | Microchip electrophoresis apparatus and microchip electrophoresis method |
Also Published As
Publication number | Publication date |
---|---|
CN101329358B (zh) | 2012-02-08 |
EP2006689A3 (en) | 2016-01-20 |
JP4982266B2 (ja) | 2012-07-25 |
US20080317639A1 (en) | 2008-12-25 |
EP2006689B1 (en) | 2017-12-20 |
EP2006689A2 (en) | 2008-12-24 |
CN101329358A (zh) | 2008-12-24 |
US8221702B2 (en) | 2012-07-17 |
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