|
US7666400B2
(en)
*
|
2005-04-06 |
2010-02-23 |
Ibc Pharmaceuticals, Inc. |
PEGylation by the dock and lock (DNL) technique
|
|
US7527787B2
(en)
*
|
2005-10-19 |
2009-05-05 |
Ibc Pharmaceuticals, Inc. |
Multivalent immunoglobulin-based bioactive assemblies
|
|
US7550143B2
(en)
*
|
2005-04-06 |
2009-06-23 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
|
US8491896B2
(en)
*
|
2002-06-14 |
2013-07-23 |
Immunomedics, Inc. |
Anti-pancreatic cancer antibodies
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US20160279239A1
(en)
|
2011-05-02 |
2016-09-29 |
Immunomedics, Inc. |
Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
|
|
US9599619B2
(en)
|
2002-06-14 |
2017-03-21 |
Immunomedics, Inc. |
Anti-pancreatic cancer antibodies
|
|
US8821868B2
(en)
|
2002-06-14 |
2014-09-02 |
Immunomedics, Inc. |
Anti-pancreatic cancer antibodies
|
|
US8574854B2
(en)
|
2002-06-14 |
2013-11-05 |
Immunomedics, Inc. |
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
|
|
US7906118B2
(en)
*
|
2005-04-06 |
2011-03-15 |
Ibc Pharmaceuticals, Inc. |
Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US9005613B2
(en)
|
2003-06-16 |
2015-04-14 |
Immunomedics, Inc. |
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
|
|
US8652484B2
(en)
|
2004-02-13 |
2014-02-18 |
Immunomedics, Inc. |
Delivery system for cytotoxic drugs by bispecific antibody pretargeting
|
|
US8491914B2
(en)
|
2004-02-13 |
2013-07-23 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for delivery of interference RNA
|
|
US9481878B2
(en)
|
2004-02-13 |
2016-11-01 |
Immunomedics, Inc. |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
|
|
US8003111B2
(en)
*
|
2005-04-06 |
2011-08-23 |
Ibc Pharmaceuticals, Inc. |
Dimeric alpha interferon pegylated site-specifically shows enhanced and prolonged efficacy in vivo
|
|
US8435539B2
(en)
*
|
2004-02-13 |
2013-05-07 |
Immunomedics, Inc. |
Delivery system for cytotoxic drugs by bispecific antibody pretargeting
|
|
US9550838B2
(en)
|
2004-02-13 |
2017-01-24 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
|
US8562988B2
(en)
*
|
2005-10-19 |
2013-10-22 |
Ibc Pharmaceuticals, Inc. |
Strategies for improved cancer vaccines
|
|
US8034352B2
(en)
|
2005-04-06 |
2011-10-11 |
Ibc Pharmaceuticals, Inc. |
Tetrameric cytokines with improved biological activity
|
|
US8883160B2
(en)
*
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
|
US8551480B2
(en)
|
2004-02-13 |
2013-10-08 |
Immunomedics, Inc. |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
|
|
US20110020273A1
(en)
*
|
2005-04-06 |
2011-01-27 |
Ibc Pharmaceuticals, Inc. |
Bispecific Immunocytokine Dock-and-Lock (DNL) Complexes and Therapeutic Use Thereof
|
|
US20110064754A1
(en)
*
|
2005-03-03 |
2011-03-17 |
Center For Molecular Medicine And Immunology |
Immunoconjugates Comprising Poxvirus-Derived Peptides and Antibodies Against Antigen-Presenting Cells for Subunit-Based Poxvirus Vaccines
|
|
JP2008523083A
(ja)
*
|
2004-12-08 |
2008-07-03 |
イムノメディクス， インコーポレイテッド |
炎症性疾患および免疫調節不全疾患、感染性疾患、病的血管新生およびがんの免疫療法および検出のための方法および組成物
|
|
US20160355591A1
(en)
|
2011-05-02 |
2016-12-08 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
|
US10058621B2
(en)
|
2015-06-25 |
2018-08-28 |
Immunomedics, Inc. |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
|
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
ES2829566T3
(es)
|
2005-03-03 |
2021-06-01 |
Immunomedics Inc |
Anticuerpos L243 humanizados
|
|
US8158129B2
(en)
|
2005-04-06 |
2012-04-17 |
Ibc Pharmaceuticals, Inc. |
Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in vivo
|
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
|
US9623115B2
(en)
|
2005-04-06 |
2017-04-18 |
Ibc Pharmaceuticals, Inc. |
Dock-and-Lock (DNL) Complexes for Disease Therapy
|
|
US9931413B2
(en)
|
2005-04-06 |
2018-04-03 |
Ibc Pharmaceuticals, Inc. |
Tetrameric cytokines with improved biological activity
|
|
CA2604032C
(en)
*
|
2005-04-06 |
2017-08-22 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
|
US8481041B2
(en)
|
2005-04-06 |
2013-07-09 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy
|
|
US8067006B2
(en)
|
2005-04-06 |
2011-11-29 |
Immunomedics, Inc. |
Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites
|
|
US8475794B2
(en)
|
2005-04-06 |
2013-07-02 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases
|
|
US20100226884A1
(en)
|
2009-01-20 |
2010-09-09 |
Immunomedics, Inc. |
Novel Class of Monospecific and Bispecific Humanized Antibodies that Target the Insulin-like Growth Factor Type I Receptor (IGF-1R)
|
|
US8883162B2
(en)
|
2005-10-19 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors
|
|
US9862770B2
(en)
|
2005-10-19 |
2018-01-09 |
Ibc Pharmaceuticals, Inc. |
Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors
|
|
BRPI0619249A2
(pt)
|
2005-11-30 |
2011-09-20 |
Abbott Lab |
anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos
|
|
PT1976877E
(pt)
|
2005-11-30 |
2014-04-29 |
Abbvie Inc |
Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
AU2007343610C1
(en)
*
|
2007-01-17 |
2013-11-07 |
Immunomedics, Inc. |
Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites
|
|
EP2124952A2
(en)
|
2007-02-27 |
2009-12-02 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
DK2158315T3
(en)
|
2007-06-25 |
2016-06-06 |
Esbatech Alcon Biomed Res Unit |
Methods of modifying antibodies and modified antibodies with improved functional properties
|
|
DE102007041831A1
(de)
*
|
2007-09-03 |
2009-03-05 |
Siemens Ag |
Kontrastmitttel für die Ultraschalluntersuchung der Prostata und Verfahren zur Diagnose von Prostatakrebs
|
|
WO2009066655A1
(ja)
*
|
2007-11-19 |
2009-05-28 |
Kagoshima University |
アポトーシス誘導能を有するヒト抗体
|
|
US9272029B2
(en)
|
2009-03-26 |
2016-03-01 |
Ibc Pharmaceuticals, Inc. |
Interferon lambada-antibody complexes
|
|
CN102186499B
(zh)
*
|
2008-08-20 |
2015-05-20 |
Ibc医药公司 |
用于癌症治疗的对接和锁定(dnl)疫苗
|
|
EP3243527B1
(en)
|
2009-02-13 |
2019-06-05 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
|
PT2430051T
(pt)
*
|
2009-05-14 |
2016-07-11 |
Inst Nat De La Santé Et De La Rech Medicale |
Composições contendo anticorpos para tratar doenças relacionadas com células b ou t cd5+ hla- dr+
|
|
GB0911566D0
(en)
*
|
2009-07-03 |
2009-08-12 |
Immunocore Ltd |
T cell receptors
|
|
CN102596235A
(zh)
*
|
2009-08-31 |
2012-07-18 |
免疫医疗公司 |
显示有效细胞毒活性的包含豹蛙酶(rap)的免疫毒素的组合物和使用方法
|
|
CN102481348A
(zh)
*
|
2009-08-31 |
2012-05-30 |
Ibc药品公司 |
双特异性免疫细胞因子停靠-和-加锁(dnl)复合物及其治疗性用途
|
|
CN105566498A
(zh)
*
|
2009-08-31 |
2016-05-11 |
Ibc药品公司 |
双特异性免疫细胞因子停靠-和-加锁(dnl)复合物及其治疗性用途
|
|
CA2774260C
(en)
|
2009-09-16 |
2018-10-09 |
Immunomedics, Inc. |
Class i anti-cea antibodies and uses thereof
|
|
AU2010315432A1
(en)
*
|
2009-11-05 |
2012-04-12 |
Center For Molecular Medicine And Immunology |
Immunoconjugates comprising poxvirus-derived peptides and antibodies against antigen-presenting cells for subunit-based poxvirus vaccines
|
|
EP2506881B1
(en)
|
2009-12-02 |
2024-03-06 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
|
WO2011085354A1
(en)
*
|
2010-01-11 |
2011-07-14 |
Center For Molecular Medicine And Immunology |
Enhanced cytotoxicity of anti-cd74 and anti-hla-dr antibodies with interferon-gamma
|
|
CA2787753A1
(en)
*
|
2010-01-22 |
2011-07-28 |
Immunomedics, Inc. |
Detection of early-stage pancreatic adenocarcinoma
|
|
EP2558494B1
(en)
|
2010-04-15 |
2018-05-23 |
AbbVie Inc. |
Amyloid-beta binding proteins
|
|
JP6017422B2
(ja)
|
2010-08-10 |
2016-11-02 |
エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ（ウペエフエル）Ｅｃｏｌｅ Ｐｏｌｙｔｅｃｈｎｉｑｕｅ Ｆｅｄｅｒａｌｅ ｄｅ Ｌａｕｓａｎｎｅ （ＥＰＦＬ） |
赤血球結合療法
|
|
US9850296B2
(en)
|
2010-08-10 |
2017-12-26 |
Ecole Polytechnique Federale De Lausanne (Epfl) |
Erythrocyte-binding therapeutics
|
|
US9517257B2
(en)
|
2010-08-10 |
2016-12-13 |
Ecole Polytechnique Federale De Lausanne (Epfl) |
Erythrocyte-binding therapeutics
|
|
CN105348387B
(zh)
|
2010-08-14 |
2020-08-25 |
Abbvie 公司 |
β淀粉样蛋白结合蛋白
|
|
EP2605788B1
(en)
*
|
2010-08-17 |
2018-10-10 |
IBC Pharmaceuticals, Inc. |
Combination therapy with anti-cd74 antibodies provides enhanced toxicity to malignancies, autoimmune disease and other diseases
|
|
AU2011323354B2
(en)
*
|
2010-11-03 |
2014-07-31 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy
|
|
US9539324B2
(en)
|
2010-12-01 |
2017-01-10 |
Alderbio Holdings, Llc |
Methods of preventing inflammation and treating pain using anti-NGF compositions
|
|
US11214610B2
(en)
|
2010-12-01 |
2022-01-04 |
H. Lundbeck A/S |
High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
|
|
US9067988B2
(en)
|
2010-12-01 |
2015-06-30 |
Alderbio Holdings Llc |
Methods of preventing or treating pain using anti-NGF antibodies
|
|
US9078878B2
(en)
|
2010-12-01 |
2015-07-14 |
Alderbio Holdings Llc |
Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
|
|
NZ611076A
(en)
|
2010-12-01 |
2015-09-25 |
Alderbio Holdings Llc |
Anti-ngf compositions and use thereof
|
|
US9884909B2
(en)
|
2010-12-01 |
2018-02-06 |
Alderbio Holdings Llc |
Anti-NGF compositions and use thereof
|
|
WO2012129520A1
(en)
*
|
2011-03-24 |
2012-09-27 |
Texas Tech University System |
Tcr mimic antibodies as vascular targeting tools
|
|
WO2012138857A2
(en)
|
2011-04-08 |
2012-10-11 |
Mayo Foundation For Medical Education And Research |
Methods and materials for reducing supression of immune function
|
|
AU2012250924B2
(en)
|
2011-05-02 |
2017-05-25 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
|
ES2672974T3
(es)
|
2012-06-01 |
2018-06-19 |
Ibc Pharmaceuticals, Inc. |
Complejos multiméricos con estabilidad in vivo, farmacocinética y eficacia mejoradas
|
|
AU2013274078A1
(en)
|
2012-06-14 |
2015-01-29 |
Ambrx, Inc. |
Anti-PSMA antibodies conjugated to nuclear receptor ligand polypeptides
|
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
|
US20150231241A1
(en)
|
2012-08-14 |
2015-08-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
|
WO2014028560A2
(en)
|
2012-08-14 |
2014-02-20 |
Ibc Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
|
US10206918B2
(en)
*
|
2012-12-13 |
2019-02-19 |
Immunomedics, Inc. |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
|
|
AU2013360335B2
(en)
|
2012-12-13 |
2017-12-07 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
|
US10137196B2
(en)
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
|
US20240148873A1
(en)
|
2012-12-13 |
2024-05-09 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and sn-38 for improved efficacy and decreased toxicity
|
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
|
WO2017004144A1
(en)
|
2015-07-01 |
2017-01-05 |
Immunomedics, Inc. |
Antibody-sn-38 immunoconjugates with a cl2a linker
|
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
|
EP2767549A1
(en)
|
2013-02-19 |
2014-08-20 |
Adienne S.A. |
Anti-CD26 antibodies and uses thereof
|
|
EP2774930A1
(en)
|
2013-03-07 |
2014-09-10 |
Aptenia S.R.L. |
Metallocene compounds and labeled molecules comprising the same for in vivo imaging.
|
|
CA3249218A1
(en)
*
|
2013-03-11 |
2026-03-02 |
Regeneron Pharmaceuticals, Inc. |
Transgenic mice expressing chimeric major histocompatibility complex (mhc) class ii molecules
|
|
US9452228B2
(en)
|
2013-04-01 |
2016-09-27 |
Immunomedics, Inc. |
Antibodies reactive with an epitope located in the N-terminal region of MUC5AC comprising cysteine-rich subdomain 2 (Cys2)
|
|
US11253606B2
(en)
|
2013-07-23 |
2022-02-22 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
CN103529202B
(zh)
*
|
2013-09-13 |
2015-04-15 |
中国科学院合肥物质科学研究院 |
一种降低野生型人鼠杂交瘤al细胞自发突变背景的方法
|
|
CA2924520C
(en)
|
2013-11-01 |
2023-09-26 |
Ibc Pharmaceuticals, Inc. |
Bispecific antibodies that neutralize both tnf-alpha and il-6: novel therapeutic agent for autoimmune disease
|
|
JP6447933B2
(ja)
|
2014-02-21 |
2019-01-09 |
アイビーシー ファーマスーティカルズ，インコーポレイテッド |
Ｔｒｏｐ−２発現細胞に対する免疫応答を誘発することによる疾患治療
|
|
US10953101B2
(en)
|
2014-02-21 |
2021-03-23 |
École Polytechnique Fédérale De Lausanne (Epfl) |
Glycotargeting therapeutics
|
|
KR20240154672A
(ko)
|
2014-02-21 |
2024-10-25 |
에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) |
글리코타겟팅 치료제
|
|
US10046056B2
(en)
|
2014-02-21 |
2018-08-14 |
École Polytechnique Fédérale De Lausanne (Epfl) |
Glycotargeting therapeutics
|
|
US10946079B2
(en)
|
2014-02-21 |
2021-03-16 |
Ecole Polytechnique Federale De Lausanne |
Glycotargeting therapeutics
|
|
CA2935748A1
(en)
|
2014-02-25 |
2015-09-03 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
|
IL292311A
(en)
|
2014-04-03 |
2022-06-01 |
Igm Biosciences Inc |
J-chain qualified
|
|
US10328149B2
(en)
|
2014-06-13 |
2019-06-25 |
Tenboron Oy |
Conjugates comprising an anti-EGFR1 antibody
|
|
EP3160504B1
(en)
|
2014-06-24 |
2020-09-16 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
|
WO2016037985A1
(en)
|
2014-09-08 |
2016-03-17 |
Ruprecht-Karls-Universität Heidelberg |
Construct for the delivery of a molecule into the cytoplasm of a cell
|
|
SI3204018T1
(sl)
|
2014-10-07 |
2021-11-30 |
Immunomedics, Inc. |
Neoadjuvantna uporaba konjugatov protitelo-zdravilo
|
|
SG11201707144VA
(en)
|
2015-03-04 |
2017-09-28 |
Igm Biosciences Inc |
Cd20 binding molecules and uses thereof
|
|
US11000603B2
(en)
|
2015-04-14 |
2021-05-11 |
Benhealth Biopharmaceutic (Shenzhen) Co., Ltd. |
Multi-specific binding conjugate, related pharmaceutical compositions and use
|
|
US9797907B2
(en)
|
2015-04-22 |
2017-10-24 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells
|
|
RU2726131C2
(ru)
*
|
2015-05-22 |
2020-07-09 |
Дмитрий Дмитриевич Генкин |
Внеклеточная днк в качестве терапевтической мишени при нейродегенерации
|
|
CN107614515B
(zh)
|
2015-05-28 |
2022-03-22 |
免疫医疗公司 |
用于抗hiv(人免疫缺陷病毒)疗法和/或疫苗的t20构建体
|
|
EP3302559B1
(en)
*
|
2015-06-04 |
2022-01-12 |
University of Southern California |
Lym-1 and lym-2 targeted car cell immunotherapy
|
|
AU2016281622C1
(en)
|
2015-06-25 |
2021-11-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
|
CA2987644A1
(en)
*
|
2015-08-21 |
2017-03-02 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
|
US10900965B2
(en)
|
2015-08-24 |
2021-01-26 |
University Of Cincinnati |
Methods and compositions for the detection of Fc receptor binding activity of antibodies
|
|
KR102773176B1
(ko)
|
2015-09-04 |
2025-02-27 |
헬스 리서치 인코포레이티드 |
암 치료용 안티-서비빈 항체
|
|
CA2999284C
(en)
|
2015-09-30 |
2023-06-13 |
Igm Biosciences A/S |
Binding molecules with modified j-chain
|
|
US11639389B2
(en)
|
2015-09-30 |
2023-05-02 |
Igm Biosciences, Inc. |
Binding molecules with modified J-chain
|
|
WO2017087843A1
(en)
*
|
2015-11-20 |
2017-05-26 |
Immungene, Inc |
Methods of treating proliferative diseases using engineered antibody-interferon fusion molecules
|
|
BR112018011100A2
(en)
|
2015-12-01 |
2018-12-04 |
Genmab B.V. |
antibody, composition, nucleic acid construct, expression vector, host cell, method for treating an individual having a cancer, kit of parts, and use of an antibody or composition.
|
|
WO2017106684A2
(en)
*
|
2015-12-17 |
2017-06-22 |
Janssen Biotech, Inc. |
Antibodies specifically binding hla-dr and their uses
|
|
WO2017139623A1
(en)
|
2016-02-10 |
2017-08-17 |
Immunomedics, Inc. |
Combination of abcg2 inhibitors with sacituzumab govitecan (immu-132) overcomes resistance to sn-38 in trop-2 expressing cancers
|
|
PL234632B1
(pl)
|
2016-03-02 |
2020-03-31 |
Inst Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk |
Przeciwciała oddziałujące z komórkami psich chłoniaków typu B i ich zastosowania
|
|
EP3448260A4
(en)
|
2016-04-27 |
2019-10-09 |
Immunomedics, Inc. |
EFFICACY OF ANTI-TROP-2 SN-38 ANTIBODY CONJUGATES FOR THE THERAPY OF REZIDIVATED / REFRACTORY TUMORS AGAINST CHECKPOINT INHIBITORS
|
|
CN109195992A
(zh)
*
|
2016-04-29 |
2019-01-11 |
本康生物制药（深圳）有限公司 |
多特异性结合偶联物、相关的药物组合物及应用
|
|
US11780924B2
(en)
|
2016-06-21 |
2023-10-10 |
University Of Oslo |
HLA binding vaccine moieties and uses thereof
|
|
CN109689692B
(zh)
|
2016-06-22 |
2021-11-12 |
本康生物制药（深圳）有限公司 |
用于肿瘤治疗的双特异性抗体和抗体偶联物及其应用
|
|
WO2018031408A1
(en)
*
|
2016-08-11 |
2018-02-15 |
Immunomedics, Inc. |
EFFICACY OF ANTI-HLA-DR ANTIBODY DRUG CONJUGATE IMMU-140 (hL243-CL2A-SN-38) IN HLA-DR POSITIVE CANCERS
|
|
AU2018240938A1
(en)
|
2017-03-24 |
2019-10-10 |
Zenyaku Kogyo Co., Ltd. |
Anti-IgM/B cell surface antigen bispecific antibody
|
|
CN110352201A
(zh)
|
2017-04-03 |
2019-10-18 |
免疫医疗公司 |
用于癌症疗法的抗体药物缀合物的皮下施用
|
|
EP3638296A1
(en)
|
2017-06-16 |
2020-04-22 |
The University Of Chicago |
Compositions and methods for inducing immune tolerance
|
|
AU2019264217B2
(en)
|
2018-05-03 |
2026-03-05 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
|
SG11202011078VA
(en)
|
2018-05-09 |
2020-12-30 |
Univ Chicago |
Compositions and methods concerning immune tolerance
|
|
US12594345B2
(en)
|
2018-09-26 |
2026-04-07 |
Ascendis Pharma A/S |
Degradable hyaluronic acid hydrogels
|
|
CA3129501A1
(en)
*
|
2019-02-15 |
2020-08-20 |
University Of Southern California |
Lym-1 and lym-2 antibody compositions and improved car constructs
|
|
US20220152228A1
(en)
*
|
2019-03-01 |
2022-05-19 |
Washington University |
Compositions and methods for radiotherapy using chelated radiotherapeutic agents and non-target tissue blockade
|
|
US20230256114A1
(en)
|
2020-07-07 |
2023-08-17 |
Bionecure Therapeutics, Inc. |
Novel maytansinoids as adc payloads and their use for the treatment of cancer
|
|
CN115803010A
(zh)
|
2020-07-09 |
2023-03-14 |
豪夫迈·罗氏有限公司 |
浓缩的蛋白质组合物、它们的制备及其用途
|
|
KR20230152032A
(ko)
|
2021-02-03 |
2023-11-02 |
모차르트 쎄라퓨틱스 인코포레이티드 |
결합제 및 이를 사용하는 방법
|
|
EP4342497A1
(en)
|
2021-05-10 |
2024-03-27 |
Kawasaki Institute of Industrial Promotion |
Antibody having reduced binding affinity for antigen
|
|
CN118043080A
(zh)
|
2021-08-13 |
2024-05-14 |
昆山新蕴达生物科技有限公司 |
一种基于微管抑制剂的抗体偶联药物
|
|
CN117881431A
(zh)
|
2021-08-24 |
2024-04-12 |
昆山新蕴达生物科技有限公司 |
一种由可断裂连接子偶联的抗体偶联药物
|
|
EP4408468A4
(en)
|
2021-09-28 |
2025-07-02 |
Frontaim Biomedicines Inc |
MULTIPLE FORMATS OF MOLECULAR COMPLEXES
|
|
WO2023076876A1
(en)
|
2021-10-26 |
2023-05-04 |
Mozart Therapeutics, Inc. |
Modulation of immune responses to viral vectors
|
|
AU2022375782B2
(en)
|
2021-10-28 |
2026-02-26 |
Gilead Sciences, Inc. |
Pyridizin-3(2h)-one derivatives
|
|
AU2022376954B2
(en)
|
2021-10-29 |
2026-04-23 |
Gilead Sciences, Inc. |
Cd73 compounds
|
|
WO2023103854A1
(zh)
|
2021-12-09 |
2023-06-15 |
昆山新蕴达生物科技有限公司 |
一种亲和力改善的抗体-药物偶联物、其制备方法及应用
|
|
AU2022419982B2
(en)
|
2021-12-22 |
2026-04-16 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
|
CA3237577A1
(en)
|
2021-12-22 |
2023-06-29 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
|
TW202340168A
(zh)
|
2022-01-28 |
2023-10-16 |
美商基利科學股份有限公司 |
Ｐａｒｐ７抑制劑
|
|
EP4493554A1
(en)
|
2022-03-17 |
2025-01-22 |
Gilead Sciences, Inc. |
Ikaros zinc finger family degraders and uses thereof
|
|
EP4508083A1
(en)
|
2022-04-13 |
2025-02-19 |
Gilead Sciences, Inc. |
Combination therapy for treating tumor antigen expressing cancers
|
|
KR20250004779A
(ko)
|
2022-04-13 |
2025-01-08 |
길리애드 사이언시즈, 인코포레이티드 |
Trop-2 발현 암을 치료하기 위한 병용 요법
|
|
CR20240451A
(es)
|
2022-04-21 |
2024-12-04 |
Gilead Sciences Inc |
Compuestos de modulación de kras g12d
|
|
PE20250758A1
(es)
|
2022-07-01 |
2025-03-13 |
Gilead Sciences Inc |
Compuestos de cd73
|
|
CN119698305A
(zh)
|
2022-08-10 |
2025-03-25 |
兴和株式会社 |
新药物复合体
|
|
CN120225509A
(zh)
|
2022-12-22 |
2025-06-27 |
吉利德科学公司 |
Prmt5抑制剂及其用途
|
|
AU2024252725A1
(en)
|
2023-04-11 |
2025-11-06 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
|
PE20260121A1
(es)
|
2023-04-21 |
2026-01-16 |
Gilead Sciences Inc |
Inhibidores de prmt5 y usos de los mismos
|
|
AU2024306338A1
(en)
|
2023-06-30 |
2026-01-08 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
|
KR20260046403A
(ko)
|
2023-07-26 |
2026-04-07 |
길리애드 사이언시즈, 인코포레이티드 |
Parp7 저해제
|
|
WO2025024811A1
(en)
|
2023-07-26 |
2025-01-30 |
Gilead Sciences, Inc. |
Parp7 inhibitors
|
|
AU2024337913A1
(en)
|
2023-09-08 |
2026-03-26 |
Gilead Sciences, Inc. |
Pyrimidine-containing polycyclic derivatives as kras g12d modulating compounds
|
|
US20250101042A1
(en)
|
2023-09-08 |
2025-03-27 |
Gilead Sciences, Inc. |
Kras g12d modulating compounds
|
|
US20250154172A1
(en)
|
2023-11-03 |
2025-05-15 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
WO2025137640A1
(en)
|
2023-12-22 |
2025-06-26 |
Gilead Sciences, Inc. |
Azaspiro wrn inhibitors
|
|
WO2025245003A1
(en)
|
2024-05-21 |
2025-11-27 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|
|
FR3163070A1
(fr)
*
|
2024-06-07 |
2025-12-12 |
Centre National De La Recherche Scientifique |
NOUVEL ANTICORPS MONOCLONAL D’ISOTYPE IgM ANTI-HLA-DR POTENTIALISANT L’ACTIVITE D’ANTICORPS D’ISOTYPE IgG1 OU IgM ANTI-CD20
|
|
WO2026039365A1
(en)
|
2024-08-12 |
2026-02-19 |
Gilead Sciences, Inc. |
Kras modulating compounds
|
|
WO2026089992A1
(en)
|
2024-10-21 |
2026-04-30 |
Gilead Sciences, Inc. |
Prmt5 inhibitors and uses thereof
|