JP2008526996A5 - - Google Patents

Download PDF

Info

Publication number
JP2008526996A5
JP2008526996A5 JP2007551428A JP2007551428A JP2008526996A5 JP 2008526996 A5 JP2008526996 A5 JP 2008526996A5 JP 2007551428 A JP2007551428 A JP 2007551428A JP 2007551428 A JP2007551428 A JP 2007551428A JP 2008526996 A5 JP2008526996 A5 JP 2008526996A5
Authority
JP
Japan
Prior art keywords
substituted
unsubstituted
group
alkyl
alkynyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007551428A
Other languages
English (en)
Japanese (ja)
Other versions
JP5253815B2 (ja
JP2008526996A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/001341 external-priority patent/WO2006076644A2/en
Publication of JP2008526996A publication Critical patent/JP2008526996A/ja
Publication of JP2008526996A5 publication Critical patent/JP2008526996A5/ja
Application granted granted Critical
Publication of JP5253815B2 publication Critical patent/JP5253815B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2007551428A 2005-01-14 2006-01-13 ヘテロアリールスルホンアミドおよびｃｃｒ２ Expired - Lifetime JP5253815B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US64410305P 2005-01-14 2005-01-14
US60/644,103 2005-01-14
US74282105P 2005-12-06 2005-12-06
US60/742,821 2005-12-06
US75098505P 2005-12-16 2005-12-16
US60/750,985 2005-12-16
PCT/US2006/001341 WO2006076644A2 (en) 2005-01-14 2006-01-13 Heteroaryl sulfonamides and ccr2

Publications (3)

Publication Number Publication Date
JP2008526996A JP2008526996A (ja) 2008-07-24
JP2008526996A5 true JP2008526996A5 (https=) 2012-05-17
JP5253815B2 JP5253815B2 (ja) 2013-07-31

Family

ID=36678244

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007551428A Expired - Lifetime JP5253815B2 (ja) 2005-01-14 2006-01-13 ヘテロアリールスルホンアミドおよびｃｃｒ２

Country Status (13)

Country Link
US (1) US20060173019A1 (https=)
EP (3) EP2354126B1 (https=)
JP (1) JP5253815B2 (https=)
AT (1) ATE503741T1 (https=)
AU (1) AU2006204750C1 (https=)
CA (1) CA2594726C (https=)
DE (1) DE602006020979D1 (https=)
DK (2) DK1838674T3 (https=)
ES (1) ES2440965T3 (https=)
IL (1) IL184539A (https=)
MX (1) MX2007008474A (https=)
PL (2) PL2354126T3 (https=)
WO (1) WO2006076644A2 (https=)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2399903A1 (en) 2002-05-24 2011-12-28 Millennium Pharmaceuticals, Inc. Ccr9 inhibitors and methods of use thereof
US6939885B2 (en) 2002-11-18 2005-09-06 Chemocentryx Aryl sulfonamides
EP1748989A2 (en) * 2004-05-12 2007-02-07 ChemoCentryx Inc Aryl sulfonamides
US7622583B2 (en) * 2005-01-14 2009-11-24 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2
US8796280B2 (en) * 2005-04-21 2014-08-05 Merck Serono, S.A. 2,3-disubstituted pyrazinesulfonamides as CRTH2 inhibitors
GB0524786D0 (en) * 2005-12-05 2006-01-11 Glaxo Group Ltd Compounds
GB0526445D0 (en) * 2005-12-23 2006-02-08 Novartis Ag Organic compounds
US20100234364A1 (en) * 2006-07-14 2010-09-16 Arindrajit Basak Ccr2 inhibitors and methods of use thereof
US7683176B2 (en) * 2006-07-14 2010-03-23 Chemocentryx, Inc. Triazolyl pyridyl benzenesulfonamides
US8519135B2 (en) * 2006-07-14 2013-08-27 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2/CCR9
US7718683B2 (en) 2006-07-14 2010-05-18 Chemocentryx, Inc. Triazolyl phenyl benzenesulfonamides
US20080076120A1 (en) * 2006-09-14 2008-03-27 Millennium Pharmaceuticals, Inc. Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders
AU2008210455A1 (en) * 2007-01-31 2008-08-07 Vertex Pharmaceuticals Incorporated 2-aminopyridine derivatives useful as kinase inhibitors
US7776877B2 (en) 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
PL2175859T3 (pl) 2007-07-12 2012-09-28 Chemocentryx Inc Skondensowane heteroarylopirydylo- i fenylo-benzenosulfonamidy jako modulatory CCR2 do leczenia zapalenia
EP2276731A1 (en) * 2008-04-09 2011-01-26 Boehringer Ingelheim International GmbH 2-sulfonylamino-4-heteroaryl butyramide antagonists of ccr10
UA103319C2 (en) 2008-05-06 2013-10-10 Глаксосмитклайн Ллк Thiazole- and oxazole-benzene sulfonamide compounds
HUE025013T2 (hu) 2009-01-12 2016-04-28 Pfizer Ltd Szulfonamid-származékok
JP5872552B2 (ja) 2010-07-09 2016-03-01 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ 化学化合物
JP5746179B2 (ja) * 2010-08-03 2015-07-08 日本ケミファ株式会社 Ｐ２ｘ４受容体拮抗剤
CA2822039C (en) * 2010-12-16 2019-05-28 Allergan, Inc. Sulfur derivatives as chemokine receptor modulators
ES2552100T3 (es) * 2010-12-16 2015-11-25 Allergan, Inc. Nuevos derivados de 1,2-bis-sulfonamida como moduladores de receptores de quimiocinas
CA2852160A1 (en) 2011-10-28 2013-05-02 Galderma Research & Development New leukocyte infiltrate markers for rosacea and uses thereof
CA2871651A1 (en) * 2012-05-08 2013-11-14 Anvyl Llc Alpha 7 nicotinic acetylcholine receptor allosteric modulators, their derivatives and uses thereof
EP3076968B1 (en) * 2013-12-02 2019-04-17 ChemoCentryx, Inc. Ccr6 compounds
EP3319968A1 (en) 2015-07-06 2018-05-16 Rodin Therapeutics, Inc. Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
LT3319959T (lt) 2015-07-06 2021-12-27 Alkermes, Inc. Histono deacetilazės hetero-halogeno inhibitoriai
SG11201810602YA (en) 2016-06-03 2018-12-28 Chemocentryx Inc Method of treating liver fibrosis
US10195188B2 (en) 2016-06-13 2019-02-05 Chemocentryx, Inc. Method of treating pancreatic cancer
US10251888B2 (en) 2016-06-13 2019-04-09 Chemocentryx, Inc. Method of treating pancreatic cancer
MX2021014356A (es) 2016-11-23 2022-11-24 Chemocentryx Inc Metodo para tratar glomeruloesclerosis segmentaria focal.
CN110494432B (zh) 2016-12-28 2022-08-12 米尼奥尔克斯治疗有限公司 异喹啉化合物，其制备方法及其在与β-半乳糖苷酶活性改变相关的病症中的治疗用途
CN106854177B (zh) * 2017-01-04 2019-10-11 苏州健雄职业技术学院 一种6-氯-4-羟基吡啶-3-甲醛的制备方法
RS62959B1 (sr) 2017-01-11 2022-03-31 Alkermes Inc Biciklični inhibitori histon-deacetilaze
US11225475B2 (en) 2017-08-07 2022-01-18 Alkermes, Inc. Substituted pyridines as inhibitors of histone deacetylase
AU2018347361A1 (en) 2017-10-11 2020-04-30 Chemocentryx, Inc. Treatment of focal segmental glomerulosclerosis with CCR2 antagonists
BR112021025888A2 (pt) 2019-07-10 2022-04-26 Chemocentryx Inc Indanos como inibidores de pd-l1
AU2020368393B2 (en) 2019-10-16 2026-01-08 Chemocentryx, Inc. Heteroaryl-biphenyl amides for the treatment of PD-L1 diseases
CN114555080B (zh) 2019-10-16 2025-10-10 凯莫森特里克斯股份有限公司 用于治疗pd-l1疾病的杂芳基联苯胺
TW202237119A (zh) 2020-12-10 2022-10-01 美商住友製藥腫瘤公司 Ａｌｋ﹘５抑制劑和彼之用途
CN113248427B (zh) * 2021-06-01 2023-05-02 苏州大学 磺酰胺基烟酸衍生物、酰胺基烟酸衍生物及其制备方法和应用
WO2023031308A1 (en) * 2021-08-31 2023-03-09 Artica Therapeutics B.V. Ccr2 inhibitors
NL2037411B1 (en) * 2024-04-08 2025-10-31 Univ Leiden Protac compounds

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901855A (en) * 1974-08-07 1975-08-26 Us Air Force Preparation of polybenzimidazoles
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4403607A (en) * 1980-05-09 1983-09-13 The Regents Of The University Of California Compatible internal bone fixation plate
JPS61113060A (ja) * 1984-11-08 1986-05-30 Fuji Photo Film Co Ltd ハロゲン化銀カラ−写真感光材料
EP0472053B1 (en) * 1990-08-20 1998-06-17 Eisai Co., Ltd. Sulfonamide derivatives
JPH06135934A (ja) * 1991-12-27 1994-05-17 Ishihara Sangyo Kaisha Ltd ピリジン誘導体又はその塩を含有するホスホリパーゼ▲ａ２▼阻害剤、抗炎症剤又は抗膵炎剤
US5514555A (en) 1993-03-12 1996-05-07 Center For Blood Research, Inc. Assays and therapeutic methods based on lymphocyte chemoattractants
US5571775A (en) * 1994-07-11 1996-11-05 Dowelanco N-aryl[1,2,4]triazolo[1,5-a]pyridine-2-sulfonamide herbicides
DE69724777T2 (de) * 1996-02-22 2004-07-15 Tularik, Inc., South San Francisco Pentafluorobenzensulfonamiden und analoge
US5780488A (en) * 1996-04-03 1998-07-14 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
AR015104A1 (es) * 1996-11-13 2001-04-18 Dowelanco Compuestos de n-arilsulfilimina sustituidos, utiles como catalizadores en la preparacion de compuestos de n-arilarilsulfonamida; proceso para preparar dichos compuestos y su uso para catalizar dicha preparacion.
GB9803228D0 (en) * 1998-02-17 1998-04-08 Zeneca Ltd Chemical compounds
EP0937711A1 (de) * 1998-02-18 1999-08-25 Roche Diagnostics GmbH Neue Thiobenzamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
JP4327915B2 (ja) * 1998-03-30 2009-09-09 株式会社デ・ウエスタン・セラピテクス研究所 スルフォンアミド誘導体
US6380206B1 (en) * 1998-11-23 2002-04-30 Cell Pathways, Inc. Method of inhibiting neoplastic cells with 4,5-diaminopyrimidine derivatives
JP2000159665A (ja) * 1998-11-27 2000-06-13 Nippon Kayaku Co Ltd リウマチの予防または治療剤
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
SG122814A1 (en) * 1999-06-28 2006-06-29 Janssen Pharmaceutica Nv Respiratory syncytial virus replication inhibitors
JP2001089412A (ja) * 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ベンゼン誘導体またはその医薬的に許容される塩
AU2001243158A1 (en) * 2000-02-18 2001-08-27 Merck And Co., Inc. Inhibitors of prenyl-protein transferase
JP2001335714A (ja) * 2000-03-22 2001-12-04 Fuji Photo Film Co Ltd アゾ色素、その製造方法、インクジェット用インク、インクジェット記録方法
US6525051B2 (en) * 2000-03-27 2003-02-25 Schering Aktiengesellschaft N-heterocyclic derivatives as NOS inhibitors
JP2002036052A (ja) * 2000-07-25 2002-02-05 Sankyo Mfg Co Ltd 自動工具交換装置
JP4233092B2 (ja) 2001-06-07 2009-03-04 ケモセントリックス， インコーポレイテッド 細胞移動アッセイ
US7468253B2 (en) 2001-06-07 2008-12-23 Chemocentryx, Inc. Method for multiple chemokine receptor screening for antagonists using RAM assay
EP1453516A2 (de) * 2001-10-17 2004-09-08 Boehringer Ingelheim Pharma GmbH & Co.KG 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren
AU2002358390A1 (en) * 2001-12-18 2003-06-30 Astrazeneca Ab Novel compounds
AU2003220401A1 (en) * 2002-03-18 2003-10-08 Bristol-Myers Squibb Company Uracil derivatives as inhibitors of tnf-alpha converting enzyme (tace) and matrix metalloproteinases
EP2399903A1 (en) * 2002-05-24 2011-12-28 Millennium Pharmaceuticals, Inc. Ccr9 inhibitors and methods of use thereof
US20070021466A1 (en) * 2002-11-18 2007-01-25 Solomon Ungashe CCR2 inhibitors and methods of use thereof
US6939885B2 (en) * 2002-11-18 2005-09-06 Chemocentryx Aryl sulfonamides
WO2004056774A2 (en) * 2002-12-19 2004-07-08 Neurogen Corporation Substituted biphenyl-4-carboxylic acid arylamide analogues as capsaicin receptor modulators
WO2004058265A1 (en) * 2002-12-24 2004-07-15 Biofocus Plc Compound libraries of 2,3-substituted pyrazine derivatives capable of binding to g-protein coupled receptors
EP1644008B1 (en) * 2003-05-29 2011-12-21 Abbott Laboratories Continuous dosing regimen with abt-751
US7393873B2 (en) * 2003-07-02 2008-07-01 Merck & Co., Inc. Arylsulfonamide derivatives
US7622583B2 (en) * 2005-01-14 2009-11-24 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2
US9715915B2 (en) 2014-10-30 2017-07-25 Samsung Electronics Co., Ltd. Magneto-resistive devices including a free layer having different magnetic properties during operations

Similar Documents

Publication Publication Date Title
JP2008526996A5 (https=)
JP2011520815A5 (https=)
JP2008510828A5 (https=)
CA2594726A1 (en) Heteroaryl sulfonamides and ccr2
JP2005504789A5 (https=)
JP2011529500A5 (https=)
JP2008508360A5 (https=)
RU2006109108A (ru) Соединения, обладающие активностью антагонистов crth2 рецепторов
JP2005508967A5 (https=)
JP2007511504A5 (https=)
JP2010540643A5 (https=)
JP2010501478A5 (https=)
JP2006508970A5 (https=)
JP2008525416A5 (https=)
JP2008504304A5 (https=)
JP2012021003A5 (https=)
JP2006507355A5 (https=)
JP2013504593A5 (https=)
JP2007517035A5 (https=)
JP2012521411A5 (https=)
RU2010101611A (ru) Полициклические производные гуанина и способы их применения
JP2007509947A5 (https=)
JP2020529988A5 (https=)
JP2006522824A5 (https=)
JP2006508979A5 (https=)