JP2008504304A5 - - Google Patents

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Publication number
JP2008504304A5
JP2008504304A5 JP2007518382A JP2007518382A JP2008504304A5 JP 2008504304 A5 JP2008504304 A5 JP 2008504304A5 JP 2007518382 A JP2007518382 A JP 2007518382A JP 2007518382 A JP2007518382 A JP 2007518382A JP 2008504304 A5 JP2008504304 A5 JP 2008504304A5
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JP
Japan
Prior art keywords
alkyl
group
compound
heteroalkyl
membered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007518382A
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English (en)
Japanese (ja)
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JP2008504304A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/023275 external-priority patent/WO2006004925A1/en
Publication of JP2008504304A publication Critical patent/JP2008504304A/ja
Publication of JP2008504304A5 publication Critical patent/JP2008504304A5/ja
Pending legal-status Critical Current

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JP2007518382A 2004-06-28 2005-06-28 テトラヒドロキナゾリン−４（３ｈ）−オン関連、及びテトラヒドロピリド［２，３−ｄ］ピリミジン−４（３ｈ）−オン関連化合物、組成物、及びそれらの使用方法 Pending JP2008504304A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58382304P 2004-06-28 2004-06-28
PCT/US2005/023275 WO2006004925A1 (en) 2004-06-28 2005-06-28 Tetrahydroquinazolin-4(3h)-one-related and tetrahydropyrido[2,3-d]pyrimidin-4(3h)-one-related compounds, compositions and methods for their use

Publications (2)

Publication Number Publication Date
JP2008504304A JP2008504304A (ja) 2008-02-14
JP2008504304A5 true JP2008504304A5 (https=) 2008-08-14

Family

ID=34982539

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007518382A Pending JP2008504304A (ja) 2004-06-28 2005-06-28 テトラヒドロキナゾリン−４（３ｈ）−オン関連、及びテトラヒドロピリド［２，３−ｄ］ピリミジン−４（３ｈ）−オン関連化合物、組成物、及びそれらの使用方法

Country Status (7)

Country Link
US (1) US7375102B2 (https=)
EP (1) EP1765818A1 (https=)
JP (1) JP2008504304A (https=)
AU (1) AU2005260630A1 (https=)
CA (1) CA2572084A1 (https=)
MX (1) MX2007000044A (https=)
WO (1) WO2006004925A1 (https=)

Families Citing this family (27)

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US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US7939538B2 (en) * 2004-06-28 2011-05-10 Amgen Inc. Compounds, compositions and methods for prevention and treatment of inflammatory and immunoregulatory disorders and diseases
TW200714610A (en) * 2005-02-16 2007-04-16 Univ Maryland CXCR3 is a gliadin receptor
US20110052612A1 (en) * 2005-05-31 2011-03-03 Ono Pharmaceutical Co., Ltd. Spiropiperidine compound and medicinal use thereof
CA2612585A1 (en) * 2005-06-27 2007-01-04 Amgen Inc. Anti-inflammatory aryl nitrile compounds
US20110034487A1 (en) * 2008-01-22 2011-02-10 Amgen Inc. Cxcr3 antagonists
US8741259B2 (en) * 2008-10-20 2014-06-03 Marvin C. Gershengorn Low molecular weight thyroid stimulating hormone receptor (TSHR) agonists
US9206154B2 (en) 2010-04-08 2015-12-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Inverse agonists and neutral antagonists for the TSH receptor
CN103687488B (zh) 2011-06-27 2015-06-10 帕里昂科学公司 化学和代谢稳定的具有钠通道阻滞剂活性的二肽
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
US9181266B2 (en) 2011-07-13 2015-11-10 Novartis Ag 2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors
EP2731940B1 (en) 2011-07-13 2015-08-19 Novartis AG 4 - piperidinyl compounds for use as tankyrase inhibitors
CN103814032A (zh) 2011-07-13 2014-05-21 诺华股份有限公司 用作端锚聚合酶抑制剂的4-氧代-3,5,7,8-四氢-4H-吡喃并[4,3-d]嘧啶基化合物
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
HUE039734T2 (hu) 2012-05-29 2019-01-28 Parion Sciences Inc Nátriumcsatorna-blokkoló aktivitású, dendrimerszerû amino-amid-származékok száraz szem és más nyálkahártya-megbetegedések kezelésére
ES2674665T3 (es) 2012-12-17 2018-07-03 Parion Sciences, Inc. Compuestos de 3,5-diamino-6-cloro-N-(N-(4-fenilbutilo)carbamimidoilo)-pirazina-2-carboxamida
CN108658876A (zh) 2012-12-17 2018-10-16 帕里昂科学公司 3,5-二氨基-6-氯-n-(n-(4-苯基丁基)甲脒基)吡嗪-2-甲酰胺化合物
CA2895512C (en) 2012-12-17 2021-10-19 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
WO2015051241A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
MX2021012208A (es) 2013-10-04 2023-01-19 Infinity Pharmaceuticals Inc Compuestos heterocíclicos y usos de los mismos.
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
NZ724368A (en) 2014-03-19 2023-07-28 Infinity Pharmaceuticals Inc Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
WO2016054491A1 (en) 2014-10-03 2016-04-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
EP4585268A3 (en) 2015-09-14 2025-10-15 Twelve Therapeutics, Inc. Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
US10759806B2 (en) 2016-03-17 2020-09-01 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors
WO2017214269A1 (en) 2016-06-08 2017-12-14 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
JP7226321B2 (ja) * 2017-09-14 2023-02-21 住友金属鉱山株式会社 近赤外線吸収繊維およびこれを用いた繊維製品、並びにそれらの製造方法

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EP0481614A1 (en) 1990-10-01 1992-04-22 Merck & Co. Inc. Substituted pyridopyrimidinones and related heterocycles as angiotensin II antagonists
US5256667A (en) * 1991-09-25 1993-10-26 Merck & Co., Inc. Quinazolinones and pyridopyrimidinones
US5202322A (en) * 1991-09-25 1993-04-13 Merck & Co., Inc. Quinazolinone and pyridopyrimidine a-II antagonists
US5756502A (en) * 1994-08-08 1998-05-26 Warner-Lambert Company Quinazolinone derivatives as cholyecystokinin (CCK) ligands
US5719144A (en) * 1995-02-22 1998-02-17 Merck & Co., Inc. Fibrinogen receptor antagonists
WO1996028444A1 (en) * 1995-03-15 1996-09-19 Pfizer Inc. 5,10-DIHYDROPYRIMIDO[4,5-b]QUINOLIN-4(1H)-ONE TYROSINE KINASE INHIBITORS
US6140064A (en) * 1996-09-10 2000-10-31 Theodor-Kocher Institute Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
FR2778662B1 (fr) * 1998-05-12 2000-06-16 Adir Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP4831906B2 (ja) * 1999-08-27 2011-12-07 ケモセントリックス， インコーポレイテッド Ｃｘｃｒ３機能を調節するための複素環式化合物および方法
AU780846B2 (en) 1999-09-16 2005-04-21 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
ATE327224T1 (de) 1999-10-27 2006-06-15 Cytokinetics Inc Chinazolinone benutzende verfahren und zusammenstellungen
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
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