JP2008526869A5 - - Google Patents

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Publication number
JP2008526869A5
JP2008526869A5 JP2007550462A JP2007550462A JP2008526869A5 JP 2008526869 A5 JP2008526869 A5 JP 2008526869A5 JP 2007550462 A JP2007550462 A JP 2007550462A JP 2007550462 A JP2007550462 A JP 2007550462A JP 2008526869 A5 JP2008526869 A5 JP 2008526869A5
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JP
Japan
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optionally substituted
heterocyclyl
aryl
alkyl
heteroaryl
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JP2007550462A
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English (en)
Japanese (ja)
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JP5123668B2 (ja
JP2008526869A (ja
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Priority claimed from PCT/US2006/000319 external-priority patent/WO2006076202A1/en
Publication of JP2008526869A publication Critical patent/JP2008526869A/ja
Publication of JP2008526869A5 publication Critical patent/JP2008526869A5/ja
Application granted granted Critical
Publication of JP5123668B2 publication Critical patent/JP5123668B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007550462A 2005-01-10 2006-01-06 医薬品としての複素環カルボキサミド化合物 Expired - Lifetime JP5123668B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64283905P 2005-01-10 2005-01-10
US60/642,839 2005-01-10
PCT/US2006/000319 WO2006076202A1 (en) 2005-01-10 2006-01-06 Heterocyclic carboxamide compounds as steroid nuclear receptors ligands

Publications (3)

Publication Number Publication Date
JP2008526869A JP2008526869A (ja) 2008-07-24
JP2008526869A5 true JP2008526869A5 (https=) 2009-03-19
JP5123668B2 JP5123668B2 (ja) 2013-01-23

Family

ID=36178222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007550462A Expired - Lifetime JP5123668B2 (ja) 2005-01-10 2006-01-06 医薬品としての複素環カルボキサミド化合物

Country Status (6)

Country Link
US (1) US20110144128A1 (https=)
EP (1) EP1844020B1 (https=)
JP (1) JP5123668B2 (https=)
AU (1) AU2006205220B2 (https=)
CA (1) CA2593156C (https=)
WO (1) WO2006076202A1 (https=)

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US8703805B2 (en) 2005-06-27 2014-04-22 Exelixis Patent Company Llc Modulators of LXR
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DE602007009549D1 (de) * 2006-08-24 2010-11-11 Univ Hiroshima Verfahren zur hohen amplifikation eines zielgens in einer säugerzelle und vektor dafür
SI2089367T1 (sl) 2006-10-31 2012-02-29 Pfizer Prod Inc Spojine pirazolina kot antagonisti mineralokortikoidnih receptorjev
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CN101679243B (zh) 2007-04-09 2012-09-26 第一三共株式会社 吡咯衍生物的阻转异构体
CA2720164A1 (en) * 2008-03-31 2009-10-08 Teva Pharmaceutical Industries Ltd. Processes for preparing sunitinib and salts thereof
AU2009258125B2 (en) * 2008-06-11 2015-01-15 Genentech, Inc. Substituted pyrroles and methods of use
WO2010098286A1 (ja) * 2009-02-25 2010-09-02 第一三共株式会社 ミネラルコルチコイド受容体拮抗薬を含有する医薬
TWI532725B (zh) 2010-01-26 2016-05-11 賽諾菲阿凡提斯公司 經氧取代之３－雜芳醯基胺基－丙酸衍生物及其作為藥物之用途
EP2977084B1 (en) 2010-05-10 2017-07-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for the treatment of fluid accumulation in and/ or under the retina
JP6180930B2 (ja) 2010-06-16 2017-08-16 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 創傷治癒過程における再上皮化を刺激するための方法及び組成物
WO2012071573A2 (en) * 2010-11-24 2012-05-31 Mount Sinai School Of Medicine Materials and methods for the prevention and treatment of cancer
TWI523844B (zh) 2011-01-26 2016-03-01 賽諾菲公司 經胺基取代之３－雜芳醯基胺基－丙酸衍生物及其作為藥物之用途
AR085013A1 (es) 2011-01-26 2013-08-07 Sanofi Aventis Derivados de acido 3-heteroaroilamino-propionico sustituidos y su uso como sustancias farmaceuticas
EP3345901A3 (en) * 2011-06-29 2018-09-12 President and Fellows of Harvard College Small molecules as antiaging agents
MY162786A (en) 2011-07-26 2017-07-14 Sanofi Sa Substituted 3-thiazoloamino-propionic acid derivatives and their use as pharmaceuticals
JP6021910B2 (ja) 2011-07-26 2016-11-09 サノフイ ３−ヘテロアロイルアミノ−プロピオン酸誘導体及び医薬としてのそれらの使用
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US20130123325A1 (en) 2011-11-14 2013-05-16 Sven Ruf Use of boceprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
WO2013072328A1 (en) 2011-11-14 2013-05-23 Sanofi Use of telaprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
DK2880025T3 (en) * 2012-08-02 2019-03-18 Nerviano Medical Sciences Srl SUBSTITUTED PYROLES ACTIVE AS KINase INHIBITORS
WO2014108336A1 (en) 2013-01-10 2014-07-17 Grünenthal GmbH Pyrazolyl-based carboxamides ii as crac channel inhibitors
JP2016508152A (ja) 2013-01-10 2016-03-17 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Ｃｒａｃチャネル阻害薬としての、ピラゾリルをベースとするカルボキサミド類ｉ
EP2978747B1 (en) 2013-03-28 2017-04-19 Sanofi Biaryl-propionic acid derivatives and their use as pharmaceuticals
CA2907903A1 (en) 2013-03-28 2014-10-02 Sanofi Biaryl-propionic acid derivatives and their use as pharmaceuticals
EP3184095A1 (en) 2013-05-23 2017-06-28 IP Gesellschaft für Management mbH Administration units comprising polymorph 1 of 2-(2-methylamino-pyrimidin-4-yl]-1h-indole-5-carboxylic acid [(s)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide
WO2015197187A1 (en) 2014-06-24 2015-12-30 Grünenthal GmbH Pyrazolyl-based carboxamides v
BR112020003725A2 (pt) 2017-10-06 2020-11-03 Forma Therapeutics, Inc. inibição da peptidase 30 específica de ubiquitina
JP7449242B2 (ja) 2018-05-17 2024-03-13 フォーマ セラピューティクス，インコーポレイテッド ユビキチン特異的ペプチダーゼ３０（ｕｓｐ３０）阻害剤として有用な縮合二環化合物
CN108840856B (zh) * 2018-05-31 2019-12-24 陈�峰 一种酯类衍生物及其在防治心脑血管疾病中的应用
CN108822079B (zh) * 2018-05-31 2019-12-06 陈刚 一种酯类衍生物及其在防治心脑血管疾病中的应用
LT3860989T (lt) 2018-10-05 2023-06-12 Forma Therapeutics, Inc. Sulieti pirolinai, kurie veikia kaip ubikvitinui specifinės proteazės 30 (ups30) inhibitoriai
CN112707854B (zh) 2019-10-25 2022-03-15 年衍药业(珠海)有限公司 吡咯酰胺类化合物及其用途
CA3216002A1 (en) * 2021-04-26 2022-11-03 Jiancheng Wang Preparation method for pyrrole amide compound
CN115784961B (zh) * 2021-09-10 2026-03-31 上海鼎雅药物化学科技有限公司 埃沙西林酮及其中间体的合成方法
CN113929591A (zh) * 2021-10-09 2022-01-14 中国科学技术大学 具有抗增殖活性的抑制剂

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