JP2008522725A - 迷走神経耳介枝用刺激装置 - Google Patents

迷走神経耳介枝用刺激装置 Download PDF

Info

Publication number
JP2008522725A
JP2008522725A JP2007545498A JP2007545498A JP2008522725A JP 2008522725 A JP2008522725 A JP 2008522725A JP 2007545498 A JP2007545498 A JP 2007545498A JP 2007545498 A JP2007545498 A JP 2007545498A JP 2008522725 A JP2008522725 A JP 2008522725A
Authority
JP
Japan
Prior art keywords
nerve
stimulation
signal
electrode
nerve stimulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007545498A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008522725A5 (enExample
Inventor
リバス,イマッド
モフィット,ジュリア
Original Assignee
カーディアック・ペースメーカーズ・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by カーディアック・ペースメーカーズ・インコーポレーテッド filed Critical カーディアック・ペースメーカーズ・インコーポレーテッド
Publication of JP2008522725A publication Critical patent/JP2008522725A/ja
Publication of JP2008522725A5 publication Critical patent/JP2008522725A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36017—External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Electrotherapy Devices (AREA)
JP2007545498A 2004-12-07 2005-11-21 迷走神経耳介枝用刺激装置 Pending JP2008522725A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/005,703 US9089691B2 (en) 2004-12-07 2004-12-07 Stimulator for auricular branch of vagus nerve
PCT/US2005/042208 WO2006062728A1 (en) 2004-12-07 2005-11-21 Stimulator for auricular branch of vagus nerve

Publications (2)

Publication Number Publication Date
JP2008522725A true JP2008522725A (ja) 2008-07-03
JP2008522725A5 JP2008522725A5 (enExample) 2009-01-15

Family

ID=36575405

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007545498A Pending JP2008522725A (ja) 2004-12-07 2005-11-21 迷走神経耳介枝用刺激装置

Country Status (4)

Country Link
US (1) US9089691B2 (enExample)
EP (1) EP1838385A1 (enExample)
JP (1) JP2008522725A (enExample)
WO (1) WO2006062728A1 (enExample)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010524519A (ja) * 2007-04-20 2010-07-22 コンスタンティン セーレシュ ヨージェフ 点刺激用装置
JP2013525069A (ja) * 2010-05-02 2013-06-20 レイク バイオサイエンシーズ リミテッド ライアビリティ カンパニー 顔面神経系または関連神経構造の耳を介した機能調整方法
JP2014018445A (ja) * 2012-07-19 2014-02-03 Tohoku Techno Arch Co Ltd 心機能監視装置付き表面式迷走神経電気刺激装置
US9272157B2 (en) 2010-05-02 2016-03-01 Nervive, Inc. Modulating function of neural structures near the ear
JP2016158914A (ja) * 2015-03-03 2016-09-05 サンリツオートメイション株式会社 突然死回避システム
US10065047B2 (en) 2013-05-20 2018-09-04 Nervive, Inc. Coordinating emergency treatment of cardiac dysfunction and non-cardiac neural dysfunction
JP2018175044A (ja) * 2017-04-05 2018-11-15 国立大学法人 鹿児島大学 分泌促進装置
JP2019513510A (ja) * 2016-04-01 2019-05-30 リヴァノヴァ ユーエスエイ インコーポレイテッド 迷走神経刺激患者の選択法
JP2019517381A (ja) * 2016-06-10 2019-06-24 チャクマク, ユスフ オズギュルCAKMAK, Yusuf Ozgur 外耳道の神経支配用電気刺激装置
KR102264557B1 (ko) * 2020-11-30 2021-06-15 서울대학교산학협력단 부정맥 치료 장치 및 상기 부정맥 치료 장치를 이용하여 사용자의 부정맥을 치료하는 방법
JP2024527041A (ja) * 2022-06-15 2024-07-19 ニューログリン インコーポレイテッド 刺激印加装置

Families Citing this family (189)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US20050209654A1 (en) * 2002-05-09 2005-09-22 Boveja Birinder R Method and system for providing adjunct (add-on) therapy for depression, anxiety and obsessive-compulsive disorders by providing electrical pulses to vagus nerve(s)
US7189204B2 (en) 2002-12-04 2007-03-13 Cardiac Pacemakers, Inc. Sleep detection using an adjustable threshold
US8606356B2 (en) 2003-09-18 2013-12-10 Cardiac Pacemakers, Inc. Autonomic arousal detection system and method
US8002553B2 (en) 2003-08-18 2011-08-23 Cardiac Pacemakers, Inc. Sleep quality data collection and evaluation
US7887493B2 (en) * 2003-09-18 2011-02-15 Cardiac Pacemakers, Inc. Implantable device employing movement sensing for detecting sleep-related disorders
WO2005028029A2 (en) 2003-08-18 2005-03-31 Cardiac Pacemakers, Inc. Patient monitoring, diagnosis, and/or therapy systems and methods
US7783353B2 (en) 2003-12-24 2010-08-24 Cardiac Pacemakers, Inc. Automatic neural stimulation modulation based on activity and circadian rhythm
US7643875B2 (en) * 2003-12-24 2010-01-05 Cardiac Pacemakers, Inc. Baroreflex stimulation system to reduce hypertension
US8126560B2 (en) 2003-12-24 2012-02-28 Cardiac Pacemakers, Inc. Stimulation lead for stimulating the baroreceptors in the pulmonary artery
US7647114B2 (en) 2003-12-24 2010-01-12 Cardiac Pacemakers, Inc. Baroreflex modulation based on monitored cardiovascular parameter
US20050149132A1 (en) 2003-12-24 2005-07-07 Imad Libbus Automatic baroreflex modulation based on cardiac activity
US7460906B2 (en) 2003-12-24 2008-12-02 Cardiac Pacemakers, Inc. Baroreflex stimulation to treat acute myocardial infarction
US7486991B2 (en) * 2003-12-24 2009-02-03 Cardiac Pacemakers, Inc. Baroreflex modulation to gradually decrease blood pressure
US7873413B2 (en) * 2006-07-24 2011-01-18 Cardiac Pacemakers, Inc. Closed loop neural stimulation synchronized to cardiac cycles
US7706884B2 (en) 2003-12-24 2010-04-27 Cardiac Pacemakers, Inc. Baroreflex stimulation synchronized to circadian rhythm
US8024050B2 (en) 2003-12-24 2011-09-20 Cardiac Pacemakers, Inc. Lead for stimulating the baroreceptors in the pulmonary artery
US20050149133A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Sensing with compensation for neural stimulator
US7509166B2 (en) 2003-12-24 2009-03-24 Cardiac Pacemakers, Inc. Automatic baroreflex modulation responsive to adverse event
US9020595B2 (en) * 2003-12-24 2015-04-28 Cardiac Pacemakers, Inc. Baroreflex activation therapy with conditional shut off
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
CA2560756A1 (en) 2004-03-25 2005-10-06 The Feinstein Institute For Medical Research Methods and devices for reducing bleed time using vagus nerve stimulation
US7747323B2 (en) 2004-06-08 2010-06-29 Cardiac Pacemakers, Inc. Adaptive baroreflex stimulation therapy for disordered breathing
US8175705B2 (en) 2004-10-12 2012-05-08 Cardiac Pacemakers, Inc. System and method for sustained baroreflex stimulation
EP2298410B1 (en) 2004-12-27 2013-10-09 The Feinstein Institute for Medical Research Treating inflammatory disorders by electrical vagus nerve stimulation
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
US7660628B2 (en) * 2005-03-23 2010-02-09 Cardiac Pacemakers, Inc. System to provide myocardial and neural stimulation
US7555341B2 (en) 2005-04-05 2009-06-30 Cardiac Pacemakers, Inc. System to treat AV-conducted ventricular tachyarrhythmia
US7493161B2 (en) 2005-05-10 2009-02-17 Cardiac Pacemakers, Inc. System and method to deliver therapy in presence of another therapy
US7542800B2 (en) * 2005-04-05 2009-06-02 Cardiac Pacemakers, Inc. Method and apparatus for synchronizing neural stimulation to cardiac cycles
US8473049B2 (en) * 2005-05-25 2013-06-25 Cardiac Pacemakers, Inc. Implantable neural stimulator with mode switching
US8406876B2 (en) * 2005-04-05 2013-03-26 Cardiac Pacemakers, Inc. Closed loop neural stimulation synchronized to cardiac cycles
US7499748B2 (en) * 2005-04-11 2009-03-03 Cardiac Pacemakers, Inc. Transvascular neural stimulation device
US20070027504A1 (en) * 2005-07-27 2007-02-01 Cyberonics, Inc. Cranial nerve stimulation to treat a hearing disorder
US7760082B2 (en) * 2005-09-21 2010-07-20 Chon Meng Wong System and method for active monitoring and diagnostics of life signs using heartbeat waveform and body temperature remotely giving the user freedom to move within its vicinity without wires attachment, gel, or adhesives
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
US10537728B2 (en) * 2005-11-10 2020-01-21 ElectroCore, LLC Vagal nerve stimulation to avert or treat stroke or transient ischemic attack
US9037247B2 (en) 2005-11-10 2015-05-19 ElectroCore, LLC Non-invasive treatment of bronchial constriction
US9119953B2 (en) * 2005-11-10 2015-09-01 ElectroCore, LLC Non-invasive treatment of a medical condition by vagus nerve stimulation
US8874227B2 (en) 2009-03-20 2014-10-28 ElectroCore, LLC Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US11351363B2 (en) * 2005-11-10 2022-06-07 Electrocore, Inc. Nerve stimulation devices and methods for treating cardiac arrhythmias
US10441780B2 (en) * 2005-11-10 2019-10-15 Electrocore, Inc. Systems and methods for vagal nerve stimulation
US8676330B2 (en) * 2009-03-20 2014-03-18 ElectroCore, LLC Electrical and magnetic stimulators used to treat migraine/sinus headache and comorbid disorders
US8874205B2 (en) * 2009-03-20 2014-10-28 ElectroCore, LLC Device and methods for non-invasive electrical stimulation and their use for vagal nerve stimulation
US20070150027A1 (en) * 2005-12-22 2007-06-28 Rogers Lesco L Non-invasive device and method for electrical stimulation of neural tissue
US20080051852A1 (en) * 2006-01-21 2008-02-28 Cerbomed Gmbh Device and method for the transdermal stimulation of a nerve of the human body
DE102006033623B4 (de) * 2006-07-18 2010-04-08 Cerbomed Gmbh System zur transkutanen Stimulation eines Nervs des menschlichen Körpers
DE102006036069B4 (de) * 2006-07-18 2008-09-04 Cerbomed Gmbh Audiologisches Übertragungssystem
US8457734B2 (en) 2006-08-29 2013-06-04 Cardiac Pacemakers, Inc. System and method for neural stimulation
US20080091255A1 (en) * 2006-10-11 2008-04-17 Cardiac Pacemakers Implantable neurostimulator for modulating cardiovascular function
US7797041B2 (en) * 2006-10-11 2010-09-14 Cardiac Pacemakers, Inc. Transcutaneous neurostimulator for modulating cardiovascular function
US7797046B2 (en) * 2006-10-11 2010-09-14 Cardiac Pacemakers, Inc. Percutaneous neurostimulator for modulating cardiovascular function
US8301239B2 (en) * 2007-01-18 2012-10-30 Cardiac Pacemakers, Inc. Systems, devices and methods for acute autonomic stimulation
US8755892B2 (en) * 2007-05-16 2014-06-17 Cardiac Pacemakers, Inc. Systems for stimulating neural targets
US8391970B2 (en) 2007-08-27 2013-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
EP2185237A1 (en) * 2007-09-13 2010-05-19 Cardiac Pacemakers, Inc. Systems for avoiding neural stimulation habituation
US8170658B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for electrical modulation of neural conduction
US8180446B2 (en) * 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method and system for cyclical neural modulation based on activity state
US8233976B2 (en) 2007-12-05 2012-07-31 The Invention Science Fund I, Llc System for transdermal chemical modulation of neural activity
US8165669B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc System for magnetic modulation of neural conduction
US8165668B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US8170659B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc Method for thermal modulation of neural activity
US20090149797A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware System for reversible chemical modulation of neural activity
US8160695B2 (en) * 2007-12-05 2012-04-17 The Invention Science Fund I, Llc System for chemical modulation of neural activity
US8195287B2 (en) * 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
WO2009146030A1 (en) 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of t-cell activity
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
GB0817092D0 (en) * 2008-09-18 2008-10-29 To Be First Ag Cranial Electrostimulation method equipment and electrode unit
GB0817091D0 (en) * 2008-09-18 2008-10-29 To Be First Ag Cranial electrostimulation electrode unit
GB0817089D0 (en) * 2008-09-18 2008-10-29 To Be First Ag Cranial Electrostimulation method and equipment
US8548593B2 (en) * 2008-11-10 2013-10-01 Cardiac Pacemakers, Inc. Distal end converter for a medical device lead
ES2452484T3 (es) 2008-11-18 2014-04-01 Setpoint Medical Corporation Dispositivos para optimizar la colocación de electrodos para la estimulación antiinflamatoria
US8428719B2 (en) 2009-04-03 2013-04-23 The General Hospital Corporation Systems and methods for respiratory-gated auricular vagal afferent nerve stimulation
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
WO2010138228A1 (en) 2009-05-26 2010-12-02 Cardiac Pacemakers, Inc. Helically formed coil for a neural cuff electrode
CN102573986B (zh) 2009-06-09 2016-01-20 赛博恩特医疗器械公司 用于无导线刺激器的具有袋部的神经封套
US8346354B2 (en) * 2009-07-28 2013-01-01 The Invention Science Fund I, Llc Determining a neuromodulation treatment regimen in response to contactlessly acquired information
US9697336B2 (en) 2009-07-28 2017-07-04 Gearbox, Llc Electronically initiating an administration of a neuromodulation treatment regimen chosen in response to contactlessly acquired information
US8374701B2 (en) * 2009-07-28 2013-02-12 The Invention Science Fund I, Llc Stimulating a nervous system component of a mammal in response to contactlessly acquired information
US8942817B2 (en) * 2009-07-28 2015-01-27 The Invention Science Fund I, Llc Broadcasting a signal indicative of a disease, disorder, or symptom determined in response to contactlessly acquired information
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
WO2014169145A1 (en) 2013-04-10 2014-10-16 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
US8548585B2 (en) 2009-12-08 2013-10-01 Cardiac Pacemakers, Inc. Concurrent therapy detection in implantable medical devices
EP2515996B1 (en) 2009-12-23 2019-09-18 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
EP2374503B1 (fr) * 2010-04-08 2012-07-11 Sorin CRM SAS Dispositif médical implantable actif de stimulation vagale à optimisation du remplissage ventriculaire
US9931272B2 (en) * 2010-05-21 2018-04-03 Gregory Sadkhin Method for reducing a person's weight through hunger control
US20230059748A1 (en) * 2010-08-19 2023-02-23 Electrocore, Inc. Non-invasive nerve stimulation to treat disorders
US20200086108A1 (en) * 2010-08-19 2020-03-19 Electrocore, Inc. Vagal nerve stimulation to reduce inflammation associated with an aneurysm
EP3002037B1 (en) 2010-09-15 2018-06-06 Cardiac Pacemakers, Inc. Automatic selection of lead configuration for a neural stimulation lead
US12594418B2 (en) 2011-03-10 2026-04-07 Electrocore, Inc. Devices and methods for nerve stimulation
DE102011100065A1 (de) * 2011-04-30 2012-10-31 Cerbomed Gmbh Vorrichtung zur kombinierten Aufbringung eines transkutanen elektrischen Stimulationsreizes und Abgabe eines akustischen Signals
EP2707094B1 (en) 2011-05-09 2016-02-03 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
US8996114B2 (en) 2011-06-28 2015-03-31 Cardiac Pacemakers, Inc. Strain relief feature for an implantable medical device lead
JP2014521400A (ja) 2011-07-07 2014-08-28 カーディアック ペースメイカーズ, インコーポレイテッド 植え込み型医療装置リード用の絶縁および安定機構
EP2827944B1 (en) 2012-03-21 2016-05-18 Cardiac Pacemakers, Inc. Systems and methods for stimulation of vagus nerve
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US9415220B1 (en) * 2012-07-31 2016-08-16 Synchromax, Inc. Auricular stimulation for inflammatory parasympathetic diseases
WO2014039569A2 (en) 2012-09-05 2014-03-13 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders
EP2903685B1 (en) 2012-10-02 2019-08-07 Cardiac Pacemakers, Inc. Pinch to open cuff electrode
EP2903686B1 (en) 2012-10-02 2018-10-24 Cardiac Pacemakers, Inc. Pinch to open cuff electrode
JP6026674B2 (ja) 2012-12-28 2016-11-16 カーディアック ペースメイカーズ, インコーポレイテッド 刺激カフ及び埋め込み器具
CN114768089A (zh) 2013-01-21 2022-07-22 卡拉健康公司 用于控制震颤的设备和方法
US12453853B2 (en) 2013-01-21 2025-10-28 Cala Health, Inc. Multi-modal stimulation for treating tremor
JP6069523B2 (ja) 2013-02-13 2017-02-01 カーディアック ペースメイカーズ, インコーポレイテッド 一体型つる状体を備えたカフ電極
US10137308B2 (en) 2013-03-15 2018-11-27 The Florida International University Board Of Trustees Electrocardiography triggered transcranial magnetic stimulation systems and methods of using the same
EP3441109A1 (en) 2013-05-30 2019-02-13 Graham H. Creasey Flexible dermal patch for a topical nerve stimulator system
US11229789B2 (en) 2013-05-30 2022-01-25 Neurostim Oab, Inc. Neuro activator with controller
US10052257B2 (en) 2013-06-13 2018-08-21 Dyansys, Inc. Method and apparatus for stimulative electrotherapy
US10130275B2 (en) * 2013-06-13 2018-11-20 Dyansys, Inc. Method and apparatus for autonomic nervous system sensitivity-point testing
US10413719B2 (en) 2016-04-15 2019-09-17 Innovative Health Solutions, Inc. Methods of treating disease using auricular peripheral nerve field stimulation
US12447332B2 (en) 2013-10-22 2025-10-21 Neuraxis, Inc. United states auricular nerve field stimulation device and methods for using the same
US9662269B2 (en) 2013-10-22 2017-05-30 Innovative Health Solutions, Inc. Systems and methods for auricular peripheral nerve field stimulation
GB2526249B (en) * 2014-03-20 2016-06-29 Branton Jakes Device for the automated non-invasive dynamically adaptive electrical stimulation of the vagus nerve
BR112016025203B1 (pt) 2014-06-02 2022-09-06 Cala Health, Inc Sistema transcutâneo para tratar um paciente que sofre de tremor
US9782584B2 (en) 2014-06-13 2017-10-10 Nervana, LLC Transcutaneous electrostimulator and methods for electric stimulation
US10130809B2 (en) 2014-06-13 2018-11-20 Nervana, LLC Transcutaneous electrostimulator and methods for electric stimulation
EP2977078B1 (fr) * 2014-07-23 2017-10-25 Sorin CRM SAS Dispositif médical implantable actif de thérapie par stimulation du nerf vague, avec ajustement dynamique des périodes de stimulation
DE102014014942A1 (de) * 2014-10-07 2016-04-07 Neuroloop GmbH Implantierbare Anordnung
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
WO2016100195A1 (en) 2014-12-15 2016-06-23 University Of Florida Research Foundation, Inc. Vagal nerve stimulation
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US11077301B2 (en) 2015-02-21 2021-08-03 NeurostimOAB, Inc. Topical nerve stimulator and sensor for bladder control
CN105310826B (zh) * 2015-03-12 2017-10-24 汪勇 一种皮肤听声装置及其听声方法
CA2988586A1 (en) 2015-06-10 2016-12-15 Cala Health, Inc. Neuromodulation system for peripheral nerve stimulation with detachable therapy unit
US20200093400A1 (en) 2015-07-31 2020-03-26 Cala Health, Inc. Systems, devices, and method for the treatment of osteoarthritis
WO2017021944A2 (en) 2015-08-06 2017-02-09 Avishai Abrahami Cognitive state alteration system integrating multiple feedback technologies
WO2017053847A1 (en) 2015-09-23 2017-03-30 Cala Health, Inc. Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
WO2017127756A1 (en) 2016-01-20 2017-07-27 Setpoint Medical Corporation Control of vagal stimulation
EP3405255B1 (en) 2016-01-20 2025-12-31 Setpoint Medical Corporation IMPLANTABLE MICROSTIMULATORS AND INDUCTION CHARGING SYSTEMS
US11344722B2 (en) 2016-01-21 2022-05-31 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
WO2017184993A1 (en) * 2016-04-22 2017-10-26 The Regents Of The University Of California Monitoring and modulation of parasympathetic nervous system
AU2017293799B2 (en) 2016-07-08 2022-10-20 Cala Health, Inc. Systems and methods for stimulating n nerves with exactly n electrodes and improved dry electrodes
CA3033662A1 (en) 2016-08-25 2018-03-01 Cala Health, Inc. Systems and methods for treating cardiac dysfunction through peripheral nerve stimulation
US10029068B2 (en) 2016-11-01 2018-07-24 Polyvagal Science LLC Methods and systems for reducing sound sensitivities and improving auditory processing, behavioral state regulation and social engagement behaviors
AU2017357747A1 (en) 2016-11-10 2019-05-30 The Research Foundation For The State University Of New York System, method and biomarkers for airway obstruction
KR102170003B1 (ko) * 2017-01-18 2020-10-26 소인 뉴로사이언스 인코포레이티드 광범위한 스펙트럼의 조정 가능한 전기 노이즈 신호의 인가를 통해 환자에게 치료를 제공하는 방법 및 시스템
EP3606604A4 (en) 2017-04-03 2020-12-16 Cala Health, Inc. PERIPHERAL NEUROMODULATION SYSTEMS, METHODS AND DEVICES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH BLADDER HYPERACTIVITY
EP3618919A4 (en) * 2017-06-26 2021-01-27 Vorso Corp. DEVICE FOR PERIPHERAL NERVE STIMULATION TO INFLUENCE THE PARASYMPATHETIC AND SYMPATHETIC ACTIVITY TO ACHIEVE THERAPEUTIC EFFECTS
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
US11484713B2 (en) 2017-08-31 2022-11-01 Arizona Board Of Regents On Behalf Of Arizona State University In-ear electrode assembly for non-invasive vagus nerve stimulation
EP3687624A4 (en) * 2017-09-29 2021-06-16 Cochlear Limited HEARING PROSTHESIS
EP3706856A4 (en) 2017-11-07 2021-08-18 Neurostim Oab, Inc. NON-INVASIVE NERVOUS ACTIVATOR WITH ADAPTIVE CIRCUIT
WO2019143790A1 (en) 2018-01-17 2019-07-25 Cala Health, Inc. Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
CA3091209C (en) 2018-03-01 2021-08-31 Polyvagal Science LLC Systems and methods for modulating physiological state
KR20210008328A (ko) 2018-03-07 2021-01-21 수부 랩스, 인크. 열 섬유의 자극을 통한 통증 완화 개선을 위한 시스템 및 방법
US11660443B2 (en) 2018-04-20 2023-05-30 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via electrical trigeminal nerve stimulation
US11369791B2 (en) * 2018-04-26 2022-06-28 Neuraxis, Inc. Auricular nerve field stimulation device
AU2019260734B2 (en) * 2018-04-26 2023-04-27 Hoolest Performance Technologies, Inc. Non-invasive nerve stimulation devices, electrode assemblies, and methods of use thereof
BR112020023522A2 (pt) 2018-05-18 2021-02-09 Musc Foundation For Research Development método de melhoria das habilidades oromotoras, sistema de estímulo do nervo craniano e método de melhoria da reabilitação muscular
EP3852618B1 (en) * 2018-09-21 2026-08-12 Battelle Memorial Institute Non-invasive and selective bioelectronic control of blood pressure
CN113711623A (zh) 2018-09-24 2021-11-26 Nesos公司 用于治疗患者疾病的耳部的神经刺激,以及相关的系统和方法
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
US10556108B1 (en) 2018-11-07 2020-02-11 Yakov Katsnelson Multichannel apparatus for Vagus nerve stimulation
KR102698131B1 (ko) 2018-11-20 2024-08-26 뉴에너치 인크 역 관계를 갖는 주파수 및 피크 전압을 적용하는 전기 자극 장치
US11351370B2 (en) 2018-12-10 2022-06-07 Spark Biomedical, Inc. Devices and methods for treating cognitive dysfunction and depression using electrical stimulation
US10695568B1 (en) 2018-12-10 2020-06-30 Spark Biomedical, Inc. Device and method for the treatment of substance use disorders
US11623088B2 (en) 2018-12-10 2023-04-11 Spark Biomedical, Inc. Devices and methods for the treatment of substance use disorders
US12502527B2 (en) 2018-12-10 2025-12-23 Spark Biomedical, Inc. Devices and methods for treating stress and improving alertness using electrical stimulation
US10967182B2 (en) 2018-12-10 2021-04-06 Spark Biomedical, Inc. Devices and methods for reducing inflammation using electrical stimulation
WO2020210786A1 (en) 2019-04-12 2020-10-15 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
US11260228B2 (en) 2019-05-21 2022-03-01 Mayo Foundation For Medical Education And Research Wearable device with tragus modulation system
US11458311B2 (en) 2019-06-26 2022-10-04 Neurostim Technologies Llc Non-invasive nerve activator patch with adaptive circuit
WO2020264496A1 (en) 2019-06-28 2020-12-30 Musc Foundation For Research Development Motion-activated, closed-loop non-invasive vagus nerve stimulation for neurorehabilitation
CN110339450A (zh) * 2019-07-17 2019-10-18 南昌大学第一附属医院 一种经耳迷走神经电刺激昏迷促醒治疗仪
US12251560B1 (en) 2019-08-13 2025-03-18 Cala Health, Inc. Connection quality determination for wearable neurostimulation systems
US12611115B2 (en) 2019-09-27 2026-04-28 Medtronic, Inc. Determining likelihood of an adverse health event based on various physiological diagnostic states
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification
EP4017580A4 (en) 2019-12-16 2023-09-06 Neurostim Technologies LLC NON-INVASIVE NERVE ACTIVATOR WITH ENHANCED CHARGE DELIVERY
JP2023507802A (ja) * 2019-12-20 2023-02-27 ネソス コープ 脳機能に影響を与える、及び/又はウェルネスを改善するための耳介神経刺激、並びに関連するシステム及び方法
JP2023512447A (ja) 2020-01-13 2023-03-27 ザ ファインスタイン インスティチューツ フォー メディカル リサーチ 脾臓への高密度集束超音波刺激による出血及び出血性疾患の治療
US11918809B2 (en) 2020-04-30 2024-03-05 Arizona Board Of Regents On Behalf Of Arizona State University System and method for automatic vagus nerve stimulation for post-stroke rehabilitation
EP4516237A3 (en) 2020-05-19 2025-04-16 Coravie Medical, Inc. Injectable hemodynamic monitoring systems
KR20230012585A (ko) 2020-05-21 2023-01-26 더 파인스타인 인스티튜츠 포 메디칼 리서치 미주 신경 자극을 위한 시스템들 및 방법들
EP4323053A4 (en) 2021-04-16 2025-03-05 Texas Medical Center SYSTEMS AND METHODS FOR STIMULATION OF TWO OR MORE NERVE BRANCHES
US12444497B2 (en) 2021-05-17 2025-10-14 Setpoint Medical Corporation Neurostimulation parameter authentication and expiration system for neurostimulation
US12324926B2 (en) 2021-06-07 2025-06-10 Neuraxis, Inc. Device and method for eradicating pathogens in nasal passages
CN117500559A (zh) * 2021-06-18 2024-02-02 科利耳有限公司 迷走神经刺激
WO2023027652A1 (en) * 2021-08-26 2023-03-02 Vagustim Saglik Teknolojileri Anonim Sirketi System for realizing the treatment of diseases and disorders via invasive stimulation of the nerves
US20250229086A1 (en) 2022-01-20 2025-07-17 Setpoint Medical Corporation Treatment of inflammatory disorders
US12667723B2 (en) 2022-04-08 2026-06-30 Patrick M. Nemechek Systems and methods for treating autism spectrum disorder, developmental disorders and other medical conditions
US12017068B2 (en) 2022-05-27 2024-06-25 Spark Biomedical, Inc. Devices and methods for treating motion sickness using electrical stimulation
US12649059B2 (en) 2022-08-05 2026-06-09 The Feinstein Institutes For Medical Research Methods for reducing bleeding in hemophilia by vagus nerve stimulation to prime platelets
US12029893B1 (en) 2023-06-14 2024-07-09 Spark Biomedical, Inc. Wearable auricular neurostimulator and methods of use
US20260090757A1 (en) * 2024-09-27 2026-04-02 David C. Shaw Wearable electrocardiogram (ecg) monitoring systems and automatic anti-arrhythmia systems

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5470685A (en) * 1977-11-17 1979-06-06 Akira Sugiyama Bipolar electric needle
JPH07116190A (ja) * 1993-10-21 1995-05-09 Nagashima Ika Kikai Kk 鼓膜麻酔器兼治療器
JPH08322825A (ja) * 1995-06-02 1996-12-10 Nippon Colin Co Ltd 麻酔深度検出装置
JP2003511163A (ja) * 1999-10-13 2003-03-25 サイベロニクス,インク. 心不全の患者の心臓毛細管の発達を促す方法
JP2003520094A (ja) * 2000-01-21 2003-07-02 インストルメンタリウム コーポレイション 医用電極
WO2003076008A1 (en) * 2002-03-14 2003-09-18 Brainsgate Ltd. Technique for blood pressure regulation
JP2003325636A (ja) * 2002-05-16 2003-11-18 Hideaki Tanaka 健康器具
WO2004000413A2 (en) * 2002-06-24 2003-12-31 Jong-Pil Chung Electric stimulator for alpha-wave derivation
JP2004275427A (ja) * 2003-03-14 2004-10-07 Terumo Corp 心臓治療装置

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4503863A (en) 1979-06-29 1985-03-12 Katims Jefferson J Method and apparatus for transcutaneous electrical stimulation
JPH01175867A (ja) * 1987-12-29 1989-07-12 Wako Corp Kk 耳に装着して治療する装置
US4865048A (en) 1987-12-31 1989-09-12 Eckerson Harold D Method and apparatus for drug free neurostimulation
US4989605A (en) 1989-03-31 1991-02-05 Joel Rossen Transcutaneous electrical nerve stimulation (TENS) device
US5713926A (en) 1990-04-25 1998-02-03 Cardiac Pacemakers, Inc. Implantable intravenous cardiac stimulation system with pulse generator housing serving as optional additional electrode
US5197471A (en) * 1990-05-24 1993-03-30 Otero Servio T A Dry medical electrode
US5263480A (en) 1991-02-01 1993-11-23 Cyberonics, Inc. Treatment of eating disorders by nerve stimulation
US5199428A (en) 1991-03-22 1993-04-06 Medtronic, Inc. Implantable electrical nerve stimulator/pacemaker with ischemia for decreasing cardiac workload
US5458625A (en) 1994-05-04 1995-10-17 Kendall; Donald E. Transcutaneous nerve stimulation device and method for using same
US5514175A (en) 1994-11-09 1996-05-07 Cerebral Stimulation, Inc. Auricular electrical stimulator
US5673692A (en) 1995-02-03 1997-10-07 Biosignals Ltd. Co. Single site, multi-variable patient monitor
US5556421A (en) 1995-02-22 1996-09-17 Intermedics, Inc. Implantable medical device with enclosed physiological parameter sensors or telemetry link
CN2291164Y (zh) 1996-12-23 1998-09-16 祝强 降压仪
US6748275B2 (en) * 1999-05-05 2004-06-08 Respironics, Inc. Vestibular stimulation system and method
US7218964B2 (en) 2000-10-26 2007-05-15 Medtronic, Inc. Closed-loop neuromodulation for prevention and treatment of cardiac conditions
CA2426810A1 (en) 2000-10-26 2002-06-13 Medtronic, Inc. Method and apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac comditions
CA2426937A1 (en) 2000-10-26 2002-05-02 Medtronic, Inc. Method and apparatus to minimize the effects of a cardiac insult
US20030149450A1 (en) 2002-02-01 2003-08-07 Mayberg Marc R. Brainstem and cerebellar modulation of cardiovascular response and disease
US20030195588A1 (en) 2002-04-16 2003-10-16 Neuropace, Inc. External ear canal interface for the treatment of neurological disorders
US7277761B2 (en) 2002-06-12 2007-10-02 Pacesetter, Inc. Vagal stimulation for improving cardiac function in heart failure or CHF patients
JP2004180988A (ja) 2002-12-04 2004-07-02 Terumo Corp 心臓治療装置
US7142917B2 (en) 2002-12-04 2006-11-28 Terumo Kabushiki Kaisha Heart treatment equipment and method for preventing fatal arrhythmia
EP1615692A2 (en) 2003-04-11 2006-01-18 Cardiac Pacemakers, Inc. Multi-parameter arrhythmia discrimination
US20050102006A1 (en) * 2003-09-25 2005-05-12 Whitehurst Todd K. Skull-mounted electrical stimulation system
US7647114B2 (en) 2003-12-24 2010-01-12 Cardiac Pacemakers, Inc. Baroreflex modulation based on monitored cardiovascular parameter
US20050165460A1 (en) * 2004-01-26 2005-07-28 Onje' Erfan Neuro-Electric-Therapy Headset
US7373204B2 (en) * 2004-08-19 2008-05-13 Lifestim, Inc. Implantable device and method for treatment of hypertension
US7536227B1 (en) 2005-01-26 2009-05-19 Pacesetter, Inc. Shielded electrode for nerve sensing
US7561923B2 (en) 2005-05-09 2009-07-14 Cardiac Pacemakers, Inc. Method and apparatus for controlling autonomic balance using neural stimulation
US20080051852A1 (en) * 2006-01-21 2008-02-28 Cerbomed Gmbh Device and method for the transdermal stimulation of a nerve of the human body
DE102006023824B4 (de) 2006-05-20 2010-01-28 Cerbomed Gmbh Vorrichtung zur transkutanen Aufbringung eines Reizes oder zur transkutanen Erfassung eines Parameters
US8755892B2 (en) 2007-05-16 2014-06-17 Cardiac Pacemakers, Inc. Systems for stimulating neural targets

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5470685A (en) * 1977-11-17 1979-06-06 Akira Sugiyama Bipolar electric needle
JPH07116190A (ja) * 1993-10-21 1995-05-09 Nagashima Ika Kikai Kk 鼓膜麻酔器兼治療器
JPH08322825A (ja) * 1995-06-02 1996-12-10 Nippon Colin Co Ltd 麻酔深度検出装置
JP2003511163A (ja) * 1999-10-13 2003-03-25 サイベロニクス,インク. 心不全の患者の心臓毛細管の発達を促す方法
JP2003520094A (ja) * 2000-01-21 2003-07-02 インストルメンタリウム コーポレイション 医用電極
WO2003076008A1 (en) * 2002-03-14 2003-09-18 Brainsgate Ltd. Technique for blood pressure regulation
JP2003325636A (ja) * 2002-05-16 2003-11-18 Hideaki Tanaka 健康器具
WO2004000413A2 (en) * 2002-06-24 2003-12-31 Jong-Pil Chung Electric stimulator for alpha-wave derivation
JP2004275427A (ja) * 2003-03-14 2004-10-07 Terumo Corp 心臓治療装置

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010524519A (ja) * 2007-04-20 2010-07-22 コンスタンティン セーレシュ ヨージェフ 点刺激用装置
JP2013525069A (ja) * 2010-05-02 2013-06-20 レイク バイオサイエンシーズ リミテッド ライアビリティ カンパニー 顔面神経系または関連神経構造の耳を介した機能調整方法
US9272157B2 (en) 2010-05-02 2016-03-01 Nervive, Inc. Modulating function of neural structures near the ear
US9339645B2 (en) 2010-05-02 2016-05-17 Nervive, Inc. Modulating function of the facial nerve system or related neural structures via the ear
US10105549B2 (en) 2010-05-02 2018-10-23 Nervive, Inc. Modulating function of neural structures near the ear
JP2014018445A (ja) * 2012-07-19 2014-02-03 Tohoku Techno Arch Co Ltd 心機能監視装置付き表面式迷走神経電気刺激装置
US10065047B2 (en) 2013-05-20 2018-09-04 Nervive, Inc. Coordinating emergency treatment of cardiac dysfunction and non-cardiac neural dysfunction
JP2016158914A (ja) * 2015-03-03 2016-09-05 サンリツオートメイション株式会社 突然死回避システム
JP2019513510A (ja) * 2016-04-01 2019-05-30 リヴァノヴァ ユーエスエイ インコーポレイテッド 迷走神経刺激患者の選択法
US11612749B2 (en) 2016-04-01 2023-03-28 Livanova Usa, Inc. Vagus nerve stimulation patient selection
JP7082116B2 (ja) 2016-06-10 2022-06-07 オズギュル チャクマク,ユスフ 外耳道の神経支配用電気刺激装置
JP2019517381A (ja) * 2016-06-10 2019-06-24 チャクマク, ユスフ オズギュルCAKMAK, Yusuf Ozgur 外耳道の神経支配用電気刺激装置
JP2018175044A (ja) * 2017-04-05 2018-11-15 国立大学法人 鹿児島大学 分泌促進装置
WO2022114621A1 (ko) * 2020-11-30 2022-06-02 서울대학교산학협력단 부정맥 치료 장치 및 상기 부정맥 치료 장치를 이용하여 사용자의 부정맥을 치료하는 방법
KR102264557B1 (ko) * 2020-11-30 2021-06-15 서울대학교산학협력단 부정맥 치료 장치 및 상기 부정맥 치료 장치를 이용하여 사용자의 부정맥을 치료하는 방법
US12521547B2 (en) 2020-11-30 2026-01-13 Seoul National University R&Db Foundation Arrhythmia treatment device and method for treating arrhythmia of user by using same
JP2024527041A (ja) * 2022-06-15 2024-07-19 ニューログリン インコーポレイテッド 刺激印加装置
JP7714270B2 (ja) 2022-06-15 2025-07-29 ニューログリン インコーポレイテッド 刺激印加装置

Also Published As

Publication number Publication date
US20060122675A1 (en) 2006-06-08
WO2006062728A1 (en) 2006-06-15
EP1838385A1 (en) 2007-10-03
US9089691B2 (en) 2015-07-28

Similar Documents

Publication Publication Date Title
US9089691B2 (en) Stimulator for auricular branch of vagus nerve
US8755892B2 (en) Systems for stimulating neural targets
JP5048656B2 (ja) 埋め込み型神経刺激装置用安全管理システム
EP2658602B1 (en) Neuro cardiac therapy using electrical impedance
JP5329089B2 (ja) 持続される圧反射刺激のためのシステム
US8818524B2 (en) Method for detecting vagus capture
JP5032593B2 (ja) 閉回路性能を含む選択的な神経刺激システム
EP2701793B1 (en) Systems to account for neck movement during nerve stimulation
JP5080262B2 (ja) 神経刺激をフィルタリングするためのシステムおよび方法
US8630716B2 (en) Systems and methods for providing neural stimulation transitions
JP5027304B2 (ja) 神経刺激の慣れを回避するためのシステム
JP2009539489A (ja) 身体状態調節システム
EP2131920A2 (en) Unidirectional neural stimulation systems, devices and methods
US9393417B2 (en) Systems and methods for using sensed pressure for neuro cardiac therapy

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20081120

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20081120

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20090309

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20090309

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20090723

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20090723

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20110830

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110912

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20111207

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20111214

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120312

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120611