|
US9321832B2
(en)
*
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
US9028822B2
(en)
|
2002-06-28 |
2015-05-12 |
Domantis Limited |
Antagonists against TNFR1 and methods of use therefor
|
|
WO2010081856A1
(en)
*
|
2009-01-14 |
2010-07-22 |
Ablynx Nv |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
|
WO2004041867A2
(en)
*
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Camelidae antibodies against imminoglobulin e and use thereof for the treatment of allergic disorders
|
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
|
CA2505316C
(en)
|
2002-11-08 |
2014-08-05 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
|
GB0521621D0
(en)
|
2005-10-24 |
2005-11-30 |
Domantis Ltd |
Tumor necrosis factor receptor 1 antagonists for treating respiratory diseases
|
|
CA2632866A1
(en)
*
|
2005-12-01 |
2007-06-07 |
Domantis Limited |
Noncompetitive domain antibody formats that bind interleukin 1 receptor type 1
|
|
EA200801166A1
(ru)
*
|
2005-12-01 |
2008-12-30 |
Домантис Лимитед |
Форматы конкурентного доменного антитела, которые связываются с рецептором интерлейкина 1 первого типа
|
|
EP3669878A1
(en)
*
|
2006-08-10 |
2020-06-24 |
Roy C. Levitt |
Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors
|
|
AU2013270447B2
(en)
*
|
2006-08-10 |
2016-10-13 |
Onspira Therapeutics, Inc. |
Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors
|
|
GB0621513D0
(en)
|
2006-10-30 |
2006-12-06 |
Domantis Ltd |
Novel polypeptides and uses thereof
|
|
GB0724331D0
(en)
*
|
2007-12-13 |
2008-01-23 |
Domantis Ltd |
Compositions for pulmonary delivery
|
|
CA2688433A1
(en)
*
|
2007-06-06 |
2008-12-11 |
Domantis Limited |
Methods for selecting protease resistant polypeptides
|
|
EP2187907A2
(en)
*
|
2007-09-11 |
2010-05-26 |
Mondobiotech Laboratories AG |
Use of tyr-w-mif-1 and urocortin 2 as therapeutic agents
|
|
CA2698666A1
(en)
*
|
2007-09-11 |
2009-03-19 |
Mondobiotech Laboratories Ag |
Use of a peptide as a therapeutic agent
|
|
CN102131827A
(zh)
*
|
2007-12-13 |
2011-07-20 |
葛兰素集团有限公司 |
用于肺部传递给药的组合物
|
|
EP2620139B1
(en)
|
2008-02-27 |
2016-07-20 |
Biomet Biologics, LLC |
Interleukin-1 receptor antagonist rich solutions
|
|
US8753690B2
(en)
|
2008-02-27 |
2014-06-17 |
Biomet Biologics, Llc |
Methods and compositions for delivering interleukin-1 receptor antagonist
|
|
EP2268668A1
(en)
|
2008-04-17 |
2011-01-05 |
Ablynx N.V. |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
|
BRPI0919714A2
(pt)
*
|
2008-10-21 |
2015-12-08 |
Domantis Ltd |
domínio variável único de imunoglobulina, polipeptídeo isolado, ligante, ácido nucleico, vetor, célula hospedeira, e, método para produzir um polipeptídeo
|
|
BRPI0919879A2
(pt)
|
2008-10-29 |
2016-02-16 |
Wyeth Llc |
métodos para purificação de moléculas de ligação a antígeno de domínio único
|
|
EP2362767B1
(en)
|
2008-10-29 |
2017-12-06 |
Ablynx N.V. |
Formulations of single domain antigen binding molecules
|
|
US8298533B2
(en)
|
2008-11-07 |
2012-10-30 |
Medimmune Limited |
Antibodies to IL-1R1
|
|
WO2010056732A1
(en)
|
2008-11-12 |
2010-05-20 |
Marv Enterprises Llc |
Utilization of stents for the treatment of blood borne carcinomas
|
|
US9216386B2
(en)
*
|
2009-03-17 |
2015-12-22 |
Marv Enterprises, LLC |
Sequential extracorporeal treatment of bodily fluids
|
|
US20100291106A1
(en)
*
|
2009-05-06 |
2010-11-18 |
Novartis Ag |
Compositions and methods for antibodies targeting complement protein c3b
|
|
ES2643034T3
(es)
*
|
2009-06-05 |
2017-11-21 |
Ablynx N.V. |
Construcciones de Nanobody contra el virus respiratorio sincicial humano (VRSH) trivalentes para la prevención y/o el tratamiento de infecciones de las vías respiratorias
|
|
CA2772084C
(en)
|
2009-08-27 |
2016-10-18 |
Biomet Biologics, Llc |
Implantable device for production of interleukin-1 receptor antagonist
|
|
CN102781959A
(zh)
|
2010-02-05 |
2012-11-14 |
埃博灵克斯股份有限公司 |
能够结合血清白蛋白的肽和包含所述肽的化合物、构建体和多肽
|
|
JP2013525310A
(ja)
*
|
2010-04-16 |
2013-06-20 |
メディミューン リミテッド |
Ｃｏｐｄ増悪を治療するための組成物および方法
|
|
KR101333958B1
(ko)
|
2010-10-20 |
2013-11-27 |
주식회사 한독 |
인간 인터루킨-1 수용체 길항제-하이브리드 Ｆｃ 융합단백질
|
|
WO2012053828A2
(ko)
*
|
2010-10-20 |
2012-04-26 |
주식회사 한독약품 |
인간 인터루킨-1 수용체 길항제-하이브리드 Ｆｃ 융합단백질
|
|
US20130266567A1
(en)
*
|
2010-12-01 |
2013-10-10 |
Haren Arulanantham |
Anti-serum albumin binding single variable domains
|
|
CN103370075A
(zh)
*
|
2011-02-15 |
2013-10-23 |
诺沃—诺迪斯克有限公司 |
长效il-1受体拮抗剂
|
|
DK2723769T4
(da)
|
2011-06-23 |
2022-09-05 |
Ablynx Nv |
Teknikker til at forudsige, påvise og reducere uspecifik proteininterferens i assays, som involverer variable immunglobulin-enkeltdomæner
|
|
EP2944653A1
(en)
|
2011-06-23 |
2015-11-18 |
Ablynx N.V. |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobin single variable domains
|
|
DK2974737T3
(da)
|
2011-06-23 |
2026-01-19 |
Ablynx Nv |
Fremgangsmåder til forudsigelse, påvisning og reduktion af en specifik proteininterferens i assays, der involverer variable immunglobulin-enkeltdomæner
|
|
US20150027950A1
(en)
*
|
2012-03-27 |
2015-01-29 |
Marv Enterprises, LLC |
Treatment for atherosclerosis
|
|
US20140271589A1
(en)
|
2013-03-15 |
2014-09-18 |
Biomet Biologics, Llc |
Treatment of collagen defects using protein solutions
|
|
US10208095B2
(en)
|
2013-03-15 |
2019-02-19 |
Biomet Manufacturing, Llc |
Methods for making cytokine compositions from tissues using non-centrifugal methods
|
|
US9878011B2
(en)
|
2013-03-15 |
2018-01-30 |
Biomet Biologics, Llc |
Treatment of inflammatory respiratory disease using biological solutions
|
|
US9758806B2
(en)
|
2013-03-15 |
2017-09-12 |
Biomet Biologics, Llc |
Acellular compositions for treating inflammatory disorders
|
|
US9950035B2
(en)
|
2013-03-15 |
2018-04-24 |
Biomet Biologics, Llc |
Methods and non-immunogenic compositions for treating inflammatory disorders
|
|
US10143725B2
(en)
|
2013-03-15 |
2018-12-04 |
Biomet Biologics, Llc |
Treatment of pain using protein solutions
|
|
US9895418B2
(en)
|
2013-03-15 |
2018-02-20 |
Biomet Biologics, Llc |
Treatment of peripheral vascular disease using protein solutions
|
|
EP3074507B1
(en)
|
2013-11-26 |
2022-01-05 |
Biomet Biologics, LLC |
Methods of mediating macrophage phenotypes
|
|
PL3248986T3
(pl)
|
2014-05-16 |
2022-05-16 |
Ablynx Nv |
Domeny zmienne immunoglobuliny
|
|
ES2900852T3
(es)
|
2014-05-16 |
2022-03-18 |
Ablynx Nv |
Métodos de detección y/o medición de anticuerpos anti-fármaco, en particular anticuerpos anti-fármaco que se presentan durante el tratamiento
|
|
PL3204095T3
(pl)
|
2014-10-10 |
2019-10-31 |
Ablynx Nv |
Urządzenie do inhalacji do stosowania w terapii aerozolowej chorób układu oddechowego
|
|
RU2017115670A
(ru)
|
2014-10-10 |
2018-11-15 |
Аблинкс Н.В. |
Лечение инфекции рсв
|
|
US9815886B2
(en)
|
2014-10-28 |
2017-11-14 |
Adma Biologics, Inc. |
Compositions and methods for the treatment of immunodeficiency
|
|
US10441635B2
(en)
|
2014-11-10 |
2019-10-15 |
Biomet Biologics, Llc |
Methods of treating pain using protein solutions
|
|
AU2015366284B2
(en)
|
2014-12-19 |
2021-07-22 |
Ablynx N.V. |
Cysteine linked nanobody dimers
|
|
US9763800B2
(en)
|
2015-03-18 |
2017-09-19 |
Biomet C. V. |
Implant configured for hammertoe and small bone fixation
|
|
NO2768984T3
(https=)
|
2015-11-12 |
2018-06-09 |
|
|
|
CN115925919A
(zh)
|
2015-11-13 |
2023-04-07 |
埃博灵克斯股份有限公司 |
改进的血清白蛋白结合免疫球蛋白可变结构域
|
|
CN120535622A
(zh)
|
2015-11-18 |
2025-08-26 |
埃博灵克斯股份有限公司 |
改进的血清白蛋白结合剂
|
|
CR20180279A
(es)
|
2015-11-18 |
2018-08-24 |
Merck Sharp & Dohme |
Enlazadores de ctla4
|
|
CA3022697A1
(en)
|
2016-05-02 |
2017-11-09 |
Ablynx Nv |
Treatment of rsv infection
|
|
MX2018016413A
(es)
|
2016-06-23 |
2019-05-09 |
Ablynx Nv |
Ensayos farmacocineticos mejorados para dominios variables unicos de inmunoglobulina.
|
|
WO2018099968A1
(en)
|
2016-11-29 |
2018-06-07 |
Ablynx N.V. |
Treatment of infection by respiratory syncytial virus (rsv)
|
|
RU2022101604A
(ru)
|
2016-12-07 |
2022-03-29 |
Аблинкс Нв |
Улучшенные отдельные вариабельные домены иммуноглобулина, связывающиеся с сывороточным альбумином
|
|
HRP20241501T1
(hr)
|
2017-01-17 |
2025-01-03 |
Ablynx Nv |
Poboljšana veziva albumina u serumu
|
|
SG10202108972RA
(en)
|
2017-01-17 |
2021-09-29 |
Ablynx Nv |
Improved serum albumin binders
|
|
US10259865B2
(en)
|
2017-03-15 |
2019-04-16 |
Adma Biologics, Inc. |
Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
|
|
EP3602056A1
(en)
|
2017-03-31 |
2020-02-05 |
Ablynx N.V. |
Improved immunogenicity assays
|
|
US20210155701A1
(en)
*
|
2018-05-30 |
2021-05-27 |
Chugai Seiyaku Kabushiki Kaisha |
Polypeptide comprising il-1r1 binding domain and carrying moiety
|
|
JP2023523600A
(ja)
|
2020-04-22 |
2023-06-06 |
マブウェル （シャンハイ） バイオサイエンス カンパニー リミテッド |
ヒトプログラム細胞死リガンド１（ｐｄ－ｌ１）を標的とする単一可変ドメイン抗体およびその誘導体
|