JP2008519128A5 - - Google Patents

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JP2008519128A5
JP2008519128A5 JP2007540022A JP2007540022A JP2008519128A5 JP 2008519128 A5 JP2008519128 A5 JP 2008519128A5 JP 2007540022 A JP2007540022 A JP 2007540022A JP 2007540022 A JP2007540022 A JP 2007540022A JP 2008519128 A5 JP2008519128 A5 JP 2008519128A5
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integer ranging
bond
daltons
cationic
polymer
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JP5436779B2 (ja
JP2008519128A (ja
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Priority claimed from US10/981,135 external-priority patent/US8057821B2/en
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一般的に、本発明のカチオン性ブロックコポリマー類は、以下の式:
(CP)xLyYz
〔式中、CPは、少なくとも1つの第2アミン基を含有するカチオン性ポリマーを示し、そのCPポリマーは1000ダルトン〜25000ダルトンの範囲内の数平均分子量を有し;Yはエステル結合、アミド結合、ジスルフィド結合、またはリン酸結合を含有する二機能性生分解性リンカーを示し;Lはリガンドを示し;xは1〜20の範囲の整数であり;yは1〜100の範囲の整数であり;そしてzは0〜40の範囲の整数である〕により示すことができる。
JP2007540022A 2004-11-03 2005-11-03 遺伝子送達用の生分解性架橋カチオン性マルチブロックコポリマーおよびそれを製造する方法 Active JP5436779B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/981,135 2004-11-03
US10/981,135 US8057821B2 (en) 2004-11-03 2004-11-03 Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof
PCT/US2005/039779 WO2006052649A2 (en) 2004-11-03 2005-11-03 Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof

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JP2008519128A JP2008519128A (ja) 2008-06-05
JP2008519128A5 true JP2008519128A5 (ja) 2013-09-05
JP5436779B2 JP5436779B2 (ja) 2014-03-05

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JP2007540022A Active JP5436779B2 (ja) 2004-11-03 2005-11-03 遺伝子送達用の生分解性架橋カチオン性マルチブロックコポリマーおよびそれを製造する方法

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US (2) US8057821B2 (ja)
EP (1) EP1807054A4 (ja)
JP (1) JP5436779B2 (ja)
KR (1) KR101208192B1 (ja)
CN (1) CN101094652B (ja)
CA (1) CA2585974C (ja)
WO (1) WO2006052649A2 (ja)

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