JP2008518973A5 - - Google Patents
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- Publication number
- JP2008518973A5 JP2008518973A5 JP2007539371A JP2007539371A JP2008518973A5 JP 2008518973 A5 JP2008518973 A5 JP 2008518973A5 JP 2007539371 A JP2007539371 A JP 2007539371A JP 2007539371 A JP2007539371 A JP 2007539371A JP 2008518973 A5 JP2008518973 A5 JP 2008518973A5
- Authority
- JP
- Japan
- Prior art keywords
- species
- microbubbles
- solution
- coated
- affinity molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 31
- 239000012491 analyte Substances 0.000 claims description 7
- 239000003599 detergent Substances 0.000 claims description 5
- 239000004094 surface-active agent Substances 0.000 claims description 5
- 108010088751 Albumins Proteins 0.000 claims description 4
- 102000009027 Albumins Human genes 0.000 claims description 4
- 239000003153 chemical reaction reagent Substances 0.000 claims description 3
- 241000894007 species Species 0.000 claims 27
- 239000000243 solution Substances 0.000 claims 19
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 15
- 102000004169 proteins and genes Human genes 0.000 claims 13
- 108090000623 proteins and genes Proteins 0.000 claims 13
- 108010090804 Streptavidin Proteins 0.000 claims 9
- 229960002685 biotin Drugs 0.000 claims 8
- 235000020958 biotin Nutrition 0.000 claims 8
- 239000011616 biotin Substances 0.000 claims 8
- 239000003446 ligand Substances 0.000 claims 8
- 108090001008 Avidin Proteins 0.000 claims 7
- 108010071390 Serum Albumin Proteins 0.000 claims 6
- 102000007562 Serum Albumin Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 241000700605 Viruses Species 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 230000005484 gravity Effects 0.000 claims 2
- 238000010438 heat treatment Methods 0.000 claims 2
- 239000005556 hormone Substances 0.000 claims 2
- 229940088597 hormone Drugs 0.000 claims 2
- 238000002955 isolation Methods 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 238000000926 separation method Methods 0.000 claims 2
- FPKVOQKZMBDBKP-UHFFFAOYSA-N 1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonic acid Chemical group O=C1C(S(=O)(=O)O)CC(=O)N1OC(=O)C1CCC(CN2C(C=CC2=O)=O)CC1 FPKVOQKZMBDBKP-UHFFFAOYSA-N 0.000 claims 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 229940098773 bovine serum albumin Drugs 0.000 claims 1
- 238000005119 centrifugation Methods 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 230000000779 depleting effect Effects 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 239000012460 protein solution Substances 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000000582 semen Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 238000000527 sonication Methods 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 239000000126 substance Substances 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62494804P | 2004-11-03 | 2004-11-03 | |
| US60/624,948 | 2004-11-03 | ||
| PCT/US2005/040162 WO2006137933A2 (en) | 2004-11-03 | 2005-11-03 | Microbubbles for affinity separation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012113421A Division JP2012197281A (ja) | 2004-11-03 | 2012-05-17 | 親和性分離のための微粒気泡 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008518973A JP2008518973A (ja) | 2008-06-05 |
| JP2008518973A5 true JP2008518973A5 (cg-RX-API-DMAC10.html) | 2012-02-02 |
| JP5037350B2 JP5037350B2 (ja) | 2012-09-26 |
Family
ID=37570908
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007539371A Expired - Fee Related JP5037350B2 (ja) | 2004-11-03 | 2005-11-03 | 親和性分離のための微粒気泡 |
| JP2012113421A Pending JP2012197281A (ja) | 2004-11-03 | 2012-05-17 | 親和性分離のための微粒気泡 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012113421A Pending JP2012197281A (ja) | 2004-11-03 | 2012-05-17 | 親和性分離のための微粒気泡 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8835186B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP2302078B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP5037350B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR101281433B1 (cg-RX-API-DMAC10.html) |
| CN (2) | CN103091485A (cg-RX-API-DMAC10.html) |
| AT (1) | ATE530666T1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2005333157B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2585675A1 (cg-RX-API-DMAC10.html) |
| DK (1) | DK1815028T3 (cg-RX-API-DMAC10.html) |
| ES (2) | ES2550177T3 (cg-RX-API-DMAC10.html) |
| PT (1) | PT1815028E (cg-RX-API-DMAC10.html) |
| WO (1) | WO2006137933A2 (cg-RX-API-DMAC10.html) |
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| US20140288421A1 (en) * | 2013-03-12 | 2014-09-25 | The Regents Of The University Of California | Gas vesicle ultrasound contrast agents and methods of using the same |
| EP2972230B1 (en) | 2013-03-15 | 2021-07-21 | Hycor Biomedical LLC | Device and associated method for performing luminescence and fluorescence measurements of a sample |
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| CN101137758B (zh) * | 2004-11-03 | 2012-10-10 | 意力速分子诊断股份有限公司 | 均相分析物检测 |
| ES2550177T3 (es) | 2004-11-03 | 2015-11-05 | Iris Molecular Diagnostics, Inc. | Microburbujas para concentración de afinidad |
| PL2252893T3 (pl) | 2008-02-21 | 2014-03-31 | Iris Int Inc | Sposób wczesnego określenia nawrotu po leczeniu nowotworu gruczołu krokowego |
-
2005
- 2005-11-03 ES ES10190637.8T patent/ES2550177T3/es not_active Expired - Lifetime
- 2005-11-03 PT PT05858304T patent/PT1815028E/pt unknown
- 2005-11-03 WO PCT/US2005/040162 patent/WO2006137933A2/en not_active Ceased
- 2005-11-03 EP EP10190637.8A patent/EP2302078B1/en not_active Expired - Lifetime
- 2005-11-03 AU AU2005333157A patent/AU2005333157B2/en not_active Ceased
- 2005-11-03 CN CN2012103784026A patent/CN103091485A/zh active Pending
- 2005-11-03 KR KR1020077012524A patent/KR101281433B1/ko not_active Expired - Fee Related
- 2005-11-03 CA CA002585675A patent/CA2585675A1/en not_active Abandoned
- 2005-11-03 ES ES05858304T patent/ES2376578T3/es not_active Expired - Lifetime
- 2005-11-03 DK DK05858304.8T patent/DK1815028T3/da active
- 2005-11-03 EP EP05858304A patent/EP1815028B1/en not_active Expired - Lifetime
- 2005-11-03 JP JP2007539371A patent/JP5037350B2/ja not_active Expired - Fee Related
- 2005-11-03 AT AT05858304T patent/ATE530666T1/de active
- 2005-11-03 US US11/718,090 patent/US8835186B2/en not_active Expired - Fee Related
- 2005-11-03 CN CN2005800380828A patent/CN101065497B/zh not_active Expired - Fee Related
-
2011
- 2011-05-31 US US13/149,551 patent/US8513032B2/en not_active Expired - Fee Related
- 2011-05-31 US US13/149,586 patent/US20110236884A1/en not_active Abandoned
-
2012
- 2012-05-17 JP JP2012113421A patent/JP2012197281A/ja active Pending
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