JP2008516968A5 - - Google Patents
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- Publication number
- JP2008516968A5 JP2008516968A5 JP2007536918A JP2007536918A JP2008516968A5 JP 2008516968 A5 JP2008516968 A5 JP 2008516968A5 JP 2007536918 A JP2007536918 A JP 2007536918A JP 2007536918 A JP2007536918 A JP 2007536918A JP 2008516968 A5 JP2008516968 A5 JP 2008516968A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- methyl
- group
- optionally substituted
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61975204P | 2004-10-18 | 2004-10-18 | |
| PCT/US2005/036940 WO2006044602A2 (en) | 2004-10-18 | 2005-10-14 | Diphenyl substituted alkanes as flap inhiibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008516968A JP2008516968A (ja) | 2008-05-22 |
| JP2008516968A5 true JP2008516968A5 (enExample) | 2008-11-20 |
Family
ID=36084258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007536918A Pending JP2008516968A (ja) | 2004-10-18 | 2005-10-14 | ジフェニル置換アルカン類 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20070287736A1 (enExample) |
| EP (1) | EP1814877B1 (enExample) |
| JP (1) | JP2008516968A (enExample) |
| CN (1) | CN101039938A (enExample) |
| AT (1) | ATE425158T1 (enExample) |
| AU (1) | AU2005295646B2 (enExample) |
| CA (1) | CA2584262A1 (enExample) |
| DE (1) | DE602005013272D1 (enExample) |
| WO (1) | WO2006044602A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200716536A (en) | 2005-06-09 | 2007-05-01 | Chugai Pharmaceutical Co Ltd | Vitamin D compounds |
| US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
| AU2006311786A1 (en) * | 2005-11-04 | 2007-05-18 | Merck Sharp & Dohme Corp. | Diphenylmethane derivatives as inhibitors of leukotriene biosynthesis |
| US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| AU2007238878A1 (en) * | 2006-04-11 | 2007-10-25 | Merck Sharp & Dohme Corp. | Diaryl substituted alkanes |
| ATE543810T1 (de) | 2006-09-01 | 2012-02-15 | Merck Sharp & Dohme | Hemmer des 5-lipoxygenase aktivierenden proteins (flap) |
| WO2008097930A1 (en) * | 2007-02-05 | 2008-08-14 | Amira Pharmaceuticals, Inc. | Reverse indoles as 5-lipoxygenase-activating protein (flap) inhibitors |
| CA2707360A1 (en) | 2007-06-20 | 2008-12-24 | Merck Sharp & Dohme Corp. | Diphenyl substituted alkanes |
| WO2009048547A1 (en) * | 2007-10-10 | 2009-04-16 | Merck & Co., Inc. | Diphenyl substituted cycloalkanes |
| JP5324082B2 (ja) * | 2007-12-20 | 2013-10-23 | 大阪瓦斯株式会社 | ９，９−ビス（カルボキシアリール）フルオレン類およびそのエステルの製造方法 |
| JP5791500B2 (ja) | 2008-05-23 | 2015-10-07 | パンミラ ファーマシューティカルズ，エルエルシー． | ５−リポキシゲナーゼ活性化タンパク質阻害剤 |
| JP5552121B2 (ja) | 2008-09-04 | 2014-07-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン産生のインドリジン阻害剤 |
| US8546431B2 (en) | 2008-10-01 | 2013-10-01 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| JP5690839B2 (ja) | 2009-12-04 | 2015-03-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン産生のベンゾイミダゾール阻害薬 |
| PH12013500301A1 (en) * | 2010-08-16 | 2013-03-25 | Boehringer Ingelheim Int | Oxadiazole inhibitors of leukotriene production |
| WO2012027322A1 (en) * | 2010-08-26 | 2012-03-01 | Boehringer Ingelheim International Gmbh | Oxadiazole inhibitors of leukotriene production |
| EA201300389A1 (ru) | 2010-09-23 | 2013-09-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Оксадиазольные ингибиторы продуцирования лейкотриена |
| EP2619196B1 (en) | 2010-09-23 | 2015-09-16 | Boehringer Ingelheim International GmbH | Oxadiazole inhibitors of leukotriene production |
| JP5928958B2 (ja) | 2010-10-29 | 2016-06-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン生成のベンゾイミダゾールインヒビター |
| WO2012061169A1 (en) | 2010-11-01 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Benzimidazole inhibitors of leukotriene production |
| EP2651930B1 (en) | 2010-12-16 | 2015-10-28 | Boehringer Ingelheim International GmbH | Biarylamide inhibitors of leukotriene production |
| WO2013116182A1 (en) * | 2012-01-31 | 2013-08-08 | Boehringer Ingelheim International Gmbh | Heterocyclic compounds as inhibitors of leukotriene production |
| AR089853A1 (es) | 2012-02-01 | 2014-09-24 | Boehringer Ingelheim Int | Inhibidores de oxadiazol de la produccion de leucotrienos para terapia de combinacion, composicion farmaceutica, uso |
| US10626096B2 (en) | 2015-11-24 | 2020-04-21 | Sanford Burnham Prebys Medical Discovery Institute | Azole derivatives as apelin receptor agonist |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4853398A (en) * | 1987-04-13 | 1989-08-01 | Eli Lilly And Company | Leukotriene antagonists and use thereas |
| US5795900A (en) * | 1995-10-03 | 1998-08-18 | Abbott Laboratories | Symmetrical bis-heteroaryl-methoxy-phenylalkyl carboxylates as inhibitors of leukotriene biosynthesis |
| NZ515087A (en) * | 1999-04-28 | 2003-11-28 | Aventis Pharma Gmbh | Tri-aryl acid derivatives as PPAR receptor ligands |
| US7629467B2 (en) * | 2003-07-24 | 2009-12-08 | Merck & Co., Inc. | Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use |
| CA2600860A1 (en) | 2005-03-09 | 2006-09-21 | Merck & Co., Inc. | Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use |
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2005
- 2005-10-14 AU AU2005295646A patent/AU2005295646B2/en not_active Ceased
- 2005-10-14 CA CA002584262A patent/CA2584262A1/en not_active Abandoned
- 2005-10-14 AT AT05804385T patent/ATE425158T1/de not_active IP Right Cessation
- 2005-10-14 EP EP05804385A patent/EP1814877B1/en not_active Expired - Lifetime
- 2005-10-14 WO PCT/US2005/036940 patent/WO2006044602A2/en not_active Ceased
- 2005-10-14 JP JP2007536918A patent/JP2008516968A/ja active Pending
- 2005-10-14 DE DE602005013272T patent/DE602005013272D1/de not_active Expired - Lifetime
- 2005-10-14 CN CNA2005800354414A patent/CN101039938A/zh active Pending
- 2005-10-14 US US11/665,242 patent/US20070287736A1/en not_active Abandoned
-
2011
- 2011-02-07 US US13/021,992 patent/US8729104B2/en not_active Expired - Fee Related