JP2008516968A5 - - Google Patents

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Publication number
JP2008516968A5
JP2008516968A5 JP2007536918A JP2007536918A JP2008516968A5 JP 2008516968 A5 JP2008516968 A5 JP 2008516968A5 JP 2007536918 A JP2007536918 A JP 2007536918A JP 2007536918 A JP2007536918 A JP 2007536918A JP 2008516968 A5 JP2008516968 A5 JP 2008516968A5
Authority
JP
Japan
Prior art keywords
phenyl
methyl
group
optionally substituted
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007536918A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008516968A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/036940 external-priority patent/WO2006044602A2/en
Publication of JP2008516968A publication Critical patent/JP2008516968A/ja
Publication of JP2008516968A5 publication Critical patent/JP2008516968A5/ja
Pending legal-status Critical Current

Links

JP2007536918A 2004-10-18 2005-10-14 ジフェニル置換アルカン類 Pending JP2008516968A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61975204P 2004-10-18 2004-10-18
PCT/US2005/036940 WO2006044602A2 (en) 2004-10-18 2005-10-14 Diphenyl substituted alkanes as flap inhiibitors

Publications (2)

Publication Number Publication Date
JP2008516968A JP2008516968A (ja) 2008-05-22
JP2008516968A5 true JP2008516968A5 (enExample) 2008-11-20

Family

ID=36084258

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007536918A Pending JP2008516968A (ja) 2004-10-18 2005-10-14 ジフェニル置換アルカン類

Country Status (9)

Country Link
US (2) US20070287736A1 (enExample)
EP (1) EP1814877B1 (enExample)
JP (1) JP2008516968A (enExample)
CN (1) CN101039938A (enExample)
AT (1) ATE425158T1 (enExample)
AU (1) AU2005295646B2 (enExample)
CA (1) CA2584262A1 (enExample)
DE (1) DE602005013272D1 (enExample)
WO (1) WO2006044602A2 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200716536A (en) 2005-06-09 2007-05-01 Chugai Pharmaceutical Co Ltd Vitamin D compounds
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
CA2628120A1 (en) * 2005-11-04 2007-05-18 Merck & Co., Inc. Diphenylmethane derivatives as inhibitors of leukotriene biosynthesis
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
EP2013174B1 (en) 2006-04-11 2013-05-08 Merck Sharp & Dohme Corp. Diaryl substituted alkanes
CA2666686A1 (en) 2006-09-01 2008-03-13 Merck & Co., Inc. Inhibitors of 5-lipoxygenase activating protein (flap)
JP2010518025A (ja) * 2007-02-05 2010-05-27 アミラ ファーマシューティカルス,インコーポレーテッド 5−リポキシゲナーゼ活性化タンパク質(flap)インヒビターとしての逆インドール
EP2546232A1 (en) * 2007-06-20 2013-01-16 Merck Sharp & Dohme Corp. Diphenyl Substituted Alkanes
AU2008311375A1 (en) * 2007-10-10 2009-04-16 Merck Sharp & Dohme Corp. Diphenyl substituted cycloalkanes
JP5324082B2 (ja) * 2007-12-20 2013-10-23 大阪瓦斯株式会社 9,9−ビス(カルボキシアリール)フルオレン類およびそのエステルの製造方法
BRPI0912267A2 (pt) 2008-05-23 2015-10-13 Amira Pharmaceuticals Inc sal farmaceuticamente aceitável, composição farmacêutica, artigo de fabricação, métodos para tratar asma, rinite alérgica, doença, lesões gástricas e dor, métodos para prevenir broncoconstrição e rinite alérgica, uso de um sal farmaceuticamente aceitável, e, processo para a preparação de um sal farmaceuticamente aceitável.
CA2735521A1 (en) 2008-09-04 2010-03-11 Boehringer Ingelheim International Gmbh Indolizine inhibitors of leukotriene production
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
JP5690839B2 (ja) 2009-12-04 2015-03-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ロイコトリエン産生のベンゾイミダゾール阻害薬
PH12013500301A1 (en) 2010-08-16 2013-03-25 Boehringer Ingelheim Int Oxadiazole inhibitors of leukotriene production
US8580829B2 (en) 2010-08-26 2013-11-12 Boehringer Ingelheim International Gmbh Oxadiazole inhibitors of leukotriene production
EA201300389A1 (ru) 2010-09-23 2013-09-30 Бёрингер Ингельхайм Интернациональ Гмбх Оксадиазольные ингибиторы продуцирования лейкотриена
WO2012040137A1 (en) 2010-09-23 2012-03-29 Boehringer Ingelheim International Gmbh Oxadiazole inhibitors of leukotriene production
EP2632915B1 (en) 2010-10-29 2015-08-12 Boehringer Ingelheim International GmbH Benzimidazole inhibitors of leukotriene production
US8772304B2 (en) 2010-11-01 2014-07-08 Boehringer Ingelheim International Gmbh Benzimidazole inhibitors of leukotriene production
EP2651930B1 (en) * 2010-12-16 2015-10-28 Boehringer Ingelheim International GmbH Biarylamide inhibitors of leukotriene production
WO2013116182A1 (en) * 2012-01-31 2013-08-08 Boehringer Ingelheim International Gmbh Heterocyclic compounds as inhibitors of leukotriene production
AR089853A1 (es) 2012-02-01 2014-09-24 Boehringer Ingelheim Int Inhibidores de oxadiazol de la produccion de leucotrienos para terapia de combinacion, composicion farmaceutica, uso
WO2017091513A1 (en) 2015-11-24 2017-06-01 Daiichi Sankyo Company, Limited Novel azole derivatives as apelin receptor agonist

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853398A (en) * 1987-04-13 1989-08-01 Eli Lilly And Company Leukotriene antagonists and use thereas
US5795900A (en) * 1995-10-03 1998-08-18 Abbott Laboratories Symmetrical bis-heteroaryl-methoxy-phenylalkyl carboxylates as inhibitors of leukotriene biosynthesis
WO2000064876A1 (en) * 1999-04-28 2000-11-02 Aventis Pharma Deutschland Gmbh Tri-aryl acid derivatives as ppar receptor ligands
WO2005009951A2 (en) * 2003-07-24 2005-02-03 Merck & Co., Inc. Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use
EP1858513A4 (en) 2005-03-09 2009-06-03 Merck & Co Inc DIPHENYL-SUBSTITUTED CYCLOALCANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHOD FOR THEIR USE

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