JP2024516033A5 - - Google Patents
Info
- Publication number
- JP2024516033A5 JP2024516033A5 JP2023567888A JP2023567888A JP2024516033A5 JP 2024516033 A5 JP2024516033 A5 JP 2024516033A5 JP 2023567888 A JP2023567888 A JP 2023567888A JP 2023567888 A JP2023567888 A JP 2023567888A JP 2024516033 A5 JP2024516033 A5 JP 2024516033A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- compound according
- cycloalkyl
- heterocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163183321P | 2021-05-03 | 2021-05-03 | |
| US63/183,321 | 2021-05-03 | ||
| PCT/EP2022/061851 WO2022233872A1 (en) | 2021-05-03 | 2022-05-03 | Orexin receptor agonists and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024516033A JP2024516033A (ja) | 2024-04-11 |
| JP2024516033A5 true JP2024516033A5 (enExample) | 2025-05-14 |
Family
ID=81940742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023567888A Pending JP2024516033A (ja) | 2021-05-03 | 2022-05-03 | オレキシン受容体アゴニスト及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240254143A1 (enExample) |
| EP (1) | EP4334323A1 (enExample) |
| JP (1) | JP2024516033A (enExample) |
| KR (1) | KR20240004802A (enExample) |
| CN (1) | CN117616030B (enExample) |
| AU (1) | AU2022269811A1 (enExample) |
| BR (1) | BR112023022050A2 (enExample) |
| CA (1) | CA3217403A1 (enExample) |
| IL (1) | IL308099A (enExample) |
| MX (1) | MX2023012971A (enExample) |
| TW (1) | TW202309051A (enExample) |
| WO (1) | WO2022233872A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20260083444A (ko) | 2019-11-25 | 2026-06-05 | 알케르메스,인코포레이티드 | 치환된 마크로사이클릭 화합물 및 관련 치료 방법 |
| US11760747B2 (en) | 2020-12-21 | 2023-09-19 | Alkermes, Inc. | Substituted piperidino compounds and related methods of treatment |
| US12006330B2 (en) | 2020-12-21 | 2024-06-11 | Alkermes, Inc. | Substituted macrocyclic compounds and related methods of treatment |
| JP7833486B2 (ja) | 2021-05-26 | 2026-03-19 | アルカーメス，インコーポレイテッド | 置換されるカルバメート大環状化合物および関連のある治療方法 |
| US20240425519A1 (en) * | 2021-11-04 | 2024-12-26 | University Of Washington | Novel spirocyclic compounds as klhdc2 ligands |
| JP2026506356A (ja) | 2023-01-31 | 2026-02-24 | ジャズ ファーマシューティカルズ アイルランド リミテッド | 大環状オレキシン受容体アゴニスト及びその使用 |
| CN116478076A (zh) * | 2023-04-26 | 2023-07-25 | 南京优氟医药科技有限公司 | 一种(2s,4s)-1-叔丁氧羰基-2-(二氟甲基)-4-羟基吡咯烷的制备方法 |
| CN122374291A (zh) | 2023-12-12 | 2026-07-10 | 爱杜西亚药品有限公司 | 作为食欲素受体调节剂的芳基砜及砜酮衍生物 |
| WO2025132542A1 (en) | 2023-12-19 | 2025-06-26 | Idorsia Pharmaceuticals Ltd | Macrocyclic orexin agonists |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0687268B1 (en) * | 1993-03-04 | 1998-05-27 | Pfizer Inc. | Spiroazacyclic derivatives as substance p antagonists |
| EP0997464B1 (en) * | 1998-10-23 | 2005-02-16 | Pfizer Inc. | 1,3,8-Triazaspiro[4,5] decanone compounds as orl1-receptor agonists |
| US8530648B2 (en) * | 2009-12-21 | 2013-09-10 | Novartis Ag | Diaza-spiro[5.5]undecanes |
| US20120101110A1 (en) * | 2010-10-26 | 2012-04-26 | Sangamesh Badiger | Diaza-spiro[5.5]undecanes |
| SG11201806429PA (en) * | 2016-02-04 | 2018-08-30 | Takeda Pharmaceuticals Co | Substituted piperidine compound and use thereof |
| US11655241B2 (en) * | 2018-06-29 | 2023-05-23 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
| US11098029B2 (en) * | 2019-02-13 | 2021-08-24 | Merck Sharp & Dohme Corp. | 5-alkyl pyrrolidine orexin receptor agonists |
-
2022
- 2022-05-03 MX MX2023012971A patent/MX2023012971A/es unknown
- 2022-05-03 WO PCT/EP2022/061851 patent/WO2022233872A1/en not_active Ceased
- 2022-05-03 KR KR1020237041381A patent/KR20240004802A/ko active Pending
- 2022-05-03 JP JP2023567888A patent/JP2024516033A/ja active Pending
- 2022-05-03 CA CA3217403A patent/CA3217403A1/en active Pending
- 2022-05-03 TW TW111116714A patent/TW202309051A/zh unknown
- 2022-05-03 IL IL308099A patent/IL308099A/en unknown
- 2022-05-03 AU AU2022269811A patent/AU2022269811A1/en active Pending
- 2022-05-03 EP EP22727800.9A patent/EP4334323A1/en active Pending
- 2022-05-03 BR BR112023022050A patent/BR112023022050A2/pt unknown
- 2022-05-03 CN CN202280045968.9A patent/CN117616030B/zh active Active
- 2022-05-03 US US18/558,245 patent/US20240254143A1/en active Pending
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