JP2008509677A5 - - Google Patents
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- JP2008509677A5 JP2008509677A5 JP2007525861A JP2007525861A JP2008509677A5 JP 2008509677 A5 JP2008509677 A5 JP 2008509677A5 JP 2007525861 A JP2007525861 A JP 2007525861A JP 2007525861 A JP2007525861 A JP 2007525861A JP 2008509677 A5 JP2008509677 A5 JP 2008509677A5
- Authority
- JP
- Japan
- Prior art keywords
- tumors
- usa
- days
- cells
- tetramer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 206010028980 Neoplasm Diseases 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 208000030507 AIDS Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000004988 splenocyte Anatomy 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60149204P | 2004-08-13 | 2004-08-13 | |
| US60/601,492 | 2004-08-13 | ||
| PCT/US2005/028895 WO2006017856A2 (en) | 2004-08-13 | 2005-08-15 | Methods for constructing antibiotic resistance free vaccines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008509677A JP2008509677A (ja) | 2008-04-03 |
| JP2008509677A5 true JP2008509677A5 (enExample) | 2008-06-26 |
| JP5530065B2 JP5530065B2 (ja) | 2014-06-25 |
Family
ID=35839990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007525861A Expired - Fee Related JP5530065B2 (ja) | 2004-08-13 | 2005-08-15 | 抗生物質耐性欠失ワクチンの作成方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US8906664B2 (enExample) |
| EP (2) | EP1789559B1 (enExample) |
| JP (1) | JP5530065B2 (enExample) |
| AU (1) | AU2005271246A1 (enExample) |
| CA (1) | CA2577306A1 (enExample) |
| DK (2) | DK1789559T3 (enExample) |
| ES (2) | ES2684749T3 (enExample) |
| PT (2) | PT2942391T (enExample) |
| WO (1) | WO2006017856A2 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8114414B2 (en) * | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
| US7820180B2 (en) * | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
| US8791237B2 (en) * | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| US7794729B2 (en) * | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
| US8956621B2 (en) | 1994-11-08 | 2015-02-17 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical dysplasia |
| US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| JP2004500405A (ja) * | 2000-03-29 | 2004-01-08 | ザ トラスティーズ オブ ザ ユニバーシティー オブ ペンシルヴァニア | 抗原の免疫原性を増強するための組成物および方法 |
| US7700344B2 (en) * | 2001-03-26 | 2010-04-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
| JP2005527240A (ja) * | 2002-05-29 | 2005-09-15 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 弱毒リステリア種とこれを使用する方法 |
| ES2684749T3 (es) | 2004-08-13 | 2018-10-04 | The Trustees Of The University Of Pennsylvania | Métodos para construir vacunas sin resistencia a antibióticos |
| EP1991263B8 (en) * | 2006-03-01 | 2015-02-25 | Aduro Biotech | Engineered listeria and methods of use thereof |
| US8277797B2 (en) * | 2006-11-22 | 2012-10-02 | The Regents Of The University Of California | Interferon-β production modulating Listeria strains and methods for using same |
| JP2010534058A (ja) * | 2007-04-16 | 2010-11-04 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 抗生物質耐性のないリステリア菌およびその構築および使用方法 |
| WO2008130551A2 (en) * | 2007-04-16 | 2008-10-30 | The Trustees Of The University Of Pennsylvania | Antibiotic resistance free listeria strains and methods for constructing and using same |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| ES2741730T3 (es) * | 2008-05-19 | 2020-02-12 | Advaxis Inc | Sistema de administración doble para antígenos heterólogos que comprende una cepa de Listeria recombinante atenuada por la mutación de dal/dat y la deleción de ActA que comprende una molécula de ácido nucleico que codifica una proteína de fusión de listeriolisina O - antígeno prostático específico |
| JP5539411B2 (ja) | 2009-03-04 | 2014-07-02 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 血管新生因子を含む組成物およびその使用方法 |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| EP2498808A4 (en) | 2009-11-11 | 2014-01-08 | Advaxis | COMPOSITIONS AND METHOD FOR PREVENTING FLUID MUTATIONS IN THE TREATMENT OF TUMORS WITH HER2 / NEW OVEREXPRESSION |
| WO2012138377A2 (en) | 2010-10-01 | 2012-10-11 | Trustees Of The University Of Pennsylvania | The use of listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals |
| WO2012125551A1 (en) | 2011-03-11 | 2012-09-20 | Advaxis | Listeria-based adjuvants |
| EP2825195A4 (en) | 2012-03-12 | 2015-10-07 | Advaxis Inc | INHIBITION OF SUPPRESSOR CELL FUNCTION AFTER TREATMENT WITH A LISTERIAL VACCINE |
| MX2016010791A (es) | 2014-02-18 | 2017-04-27 | Advaxis Inc | Inmunoterapia con multiples objetivos dirigida por biomarcadores. |
| MA39717A (fr) * | 2014-03-05 | 2017-01-11 | Advaxis Inc | Procédés et compositions pour accroître le rapport des lymphocytes t effecteurs aux lymphocytes t régulateurs |
| MA39849A (fr) * | 2014-04-24 | 2017-03-01 | Advaxis Inc | Souches de listeria utilisées comme vaccin recombinant et procédé de production |
| US20160228530A1 (en) * | 2014-10-14 | 2016-08-11 | The Trustees Of The University Of Pennsylvania | Combination therapy for use in cancer therapy |
| MA41644A (fr) | 2015-03-03 | 2018-01-09 | Advaxis Inc | Compositions à base de listeria comprenant un système d'expression de minigènes codant pour des peptides, et leurs procédés d'utilisation |
| EP3313376A2 (en) * | 2015-06-26 | 2018-05-02 | Bayer Animal Health GmbH | Methods of modulating cytosolic dna surveillance molecules |
| CN108138123A (zh) * | 2015-09-02 | 2018-06-08 | 加利福尼亚大学董事会 | 用于调节李斯特菌属某些种中prfa介导的毒力基因活化的方法和组合物 |
| HK1258860A1 (zh) * | 2015-09-15 | 2019-11-22 | Advaxis, Inc. | 含有重组李斯特氏菌株的免疫治疗制剂的制作方法 |
| MX2019005685A (es) | 2016-11-30 | 2019-09-04 | Advaxis Inc | Composiciones inmunogenicas contra mutaciones de cancer recurrentes y metodos de uso de las mismas. |
| KR102748132B1 (ko) | 2017-09-19 | 2025-01-02 | 어드박시스, 인크. | 박테리아 또는 리스테리아 균주의 동결건조를 위한 조성물 및 방법 |
| CN111349645B (zh) * | 2018-12-24 | 2022-05-17 | 上海若泰医药科技有限公司 | 一种提高非整合减毒李斯特菌疫苗安全性的方法 |
| KR102052108B1 (ko) * | 2019-08-16 | 2019-12-04 | 주식회사 쎌바이오텍 | 영양요구성 마커를 포함하는 재조합 플라스미드, 이를 포함하는 항암 약물 위장관 전달용 미생물 및 그를 포함하는 항암 약제학적 조성물 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US5204252A (en) | 1989-02-08 | 1993-04-20 | Henkel Research Corporation | Candida tropicalis transformation system |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| US5922583A (en) | 1995-10-17 | 1999-07-13 | Biostar Inc. | Methods for production of recombinant plasmids |
| US6099848A (en) * | 1997-11-18 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use |
| US6855320B2 (en) | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
| JP2004500405A (ja) | 2000-03-29 | 2004-01-08 | ザ トラスティーズ オブ ザ ユニバーシティー オブ ペンシルヴァニア | 抗原の免疫原性を増強するための組成物および方法 |
| TWI221854B (en) | 2000-05-26 | 2004-10-11 | Anawrahta Biotech Co Ltd | Lac shuttle vectors, kit for expression of a heterologous gene and DNA vaccine carrier containing the same |
| JP2002253253A (ja) | 2001-03-01 | 2002-09-10 | Toyobo Co Ltd | 新規ｄｎａ断片及びグラム陰性細菌用新規ベクター |
| JP2002253212A (ja) | 2001-03-02 | 2002-09-10 | Yamaguchi Technology Licensing Organization Ltd | 有用酵母の栄養要求性変異株とその育種方法 |
| DE50103240D1 (de) | 2001-09-05 | 2004-09-16 | Ferro Gmbh | Strahlenhärtbares Edelmetallpräparat, dieses enthaltende Abziehbilder und Verfahren zum Dekorieren |
| US7425449B2 (en) | 2002-04-30 | 2008-09-16 | The Regents Of The University Of California | Site specific Listeria integration vectors and methods for using the same |
| GB0211459D0 (en) | 2002-05-18 | 2002-06-26 | Cobra Therapeutics Ltd | Plasmid stabilisation in vivo |
| FI116068B (fi) | 2003-09-15 | 2005-09-15 | Fit Biotech Oyj Plc | Uusi selektiojärjestelmä, siinä käyttökelpoinen vektori, bakteerisolukantoja sekä menetelmä solujen valikoimiseksi |
| ES2684749T3 (es) | 2004-08-13 | 2018-10-04 | The Trustees Of The University Of Pennsylvania | Métodos para construir vacunas sin resistencia a antibióticos |
| US7855064B2 (en) * | 2004-08-13 | 2010-12-21 | The Trustees Of The University Of Pennsylvania | Antibiotic resistance free vaccines and methods for constructing and using same |
-
2005
- 2005-08-15 ES ES15167706.9T patent/ES2684749T3/es not_active Expired - Lifetime
- 2005-08-15 US US11/203,415 patent/US8906664B2/en active Active - Reinstated
- 2005-08-15 ES ES05808671.1T patent/ES2543079T3/es not_active Expired - Lifetime
- 2005-08-15 AU AU2005271246A patent/AU2005271246A1/en not_active Abandoned
- 2005-08-15 EP EP05808671.1A patent/EP1789559B1/en not_active Expired - Lifetime
- 2005-08-15 WO PCT/US2005/028895 patent/WO2006017856A2/en not_active Ceased
- 2005-08-15 CA CA002577306A patent/CA2577306A1/en not_active Abandoned
- 2005-08-15 PT PT15167706T patent/PT2942391T/pt unknown
- 2005-08-15 EP EP15167706.9A patent/EP2942391B1/en not_active Expired - Lifetime
- 2005-08-15 DK DK05808671.1T patent/DK1789559T3/en active
- 2005-08-15 DK DK15167706.9T patent/DK2942391T3/en active
- 2005-08-15 JP JP2007525861A patent/JP5530065B2/ja not_active Expired - Fee Related
- 2005-08-15 PT PT58086711T patent/PT1789559E/pt unknown
-
2014
- 2014-11-10 US US14/537,599 patent/US9492527B2/en not_active Expired - Lifetime
-
2016
- 2016-10-18 US US15/296,973 patent/US9700608B2/en not_active Expired - Lifetime
-
2017
- 2017-06-13 US US15/621,411 patent/US10426823B2/en not_active Expired - Lifetime
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