CA2577306A1 - Methods for constructing antibiotic resistance free vaccines - Google Patents
Methods for constructing antibiotic resistance free vaccines Download PDFInfo
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- CA2577306A1 CA2577306A1 CA002577306A CA2577306A CA2577306A1 CA 2577306 A1 CA2577306 A1 CA 2577306A1 CA 002577306 A CA002577306 A CA 002577306A CA 2577306 A CA2577306 A CA 2577306A CA 2577306 A1 CA2577306 A1 CA 2577306A1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60149204P | 2004-08-13 | 2004-08-13 | |
| US60/601,492 | 2004-08-13 | ||
| PCT/US2005/028895 WO2006017856A2 (en) | 2004-08-13 | 2005-08-15 | Methods for constructing antibiotic resistance free vaccines |
Publications (1)
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| US8114414B2 (en) * | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
| US7820180B2 (en) * | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
| US8791237B2 (en) * | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| US7794729B2 (en) * | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
| US8956621B2 (en) | 1994-11-08 | 2015-02-17 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical dysplasia |
| US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| JP2004500405A (ja) * | 2000-03-29 | 2004-01-08 | ザ トラスティーズ オブ ザ ユニバーシティー オブ ペンシルヴァニア | 抗原の免疫原性を増強するための組成物および方法 |
| US7700344B2 (en) * | 2001-03-26 | 2010-04-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
| JP2005527240A (ja) * | 2002-05-29 | 2005-09-15 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 弱毒リステリア種とこれを使用する方法 |
| ES2684749T3 (es) | 2004-08-13 | 2018-10-04 | The Trustees Of The University Of Pennsylvania | Métodos para construir vacunas sin resistencia a antibióticos |
| EP1991263B8 (en) * | 2006-03-01 | 2015-02-25 | Aduro Biotech | Engineered listeria and methods of use thereof |
| US8277797B2 (en) * | 2006-11-22 | 2012-10-02 | The Regents Of The University Of California | Interferon-β production modulating Listeria strains and methods for using same |
| JP2010534058A (ja) * | 2007-04-16 | 2010-11-04 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 抗生物質耐性のないリステリア菌およびその構築および使用方法 |
| WO2008130551A2 (en) * | 2007-04-16 | 2008-10-30 | The Trustees Of The University Of Pennsylvania | Antibiotic resistance free listeria strains and methods for constructing and using same |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| ES2741730T3 (es) * | 2008-05-19 | 2020-02-12 | Advaxis Inc | Sistema de administración doble para antígenos heterólogos que comprende una cepa de Listeria recombinante atenuada por la mutación de dal/dat y la deleción de ActA que comprende una molécula de ácido nucleico que codifica una proteína de fusión de listeriolisina O - antígeno prostático específico |
| JP5539411B2 (ja) | 2009-03-04 | 2014-07-02 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 血管新生因子を含む組成物およびその使用方法 |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| EP2498808A4 (en) | 2009-11-11 | 2014-01-08 | Advaxis | COMPOSITIONS AND METHOD FOR PREVENTING FLUID MUTATIONS IN THE TREATMENT OF TUMORS WITH HER2 / NEW OVEREXPRESSION |
| WO2012138377A2 (en) | 2010-10-01 | 2012-10-11 | Trustees Of The University Of Pennsylvania | The use of listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals |
| WO2012125551A1 (en) | 2011-03-11 | 2012-09-20 | Advaxis | Listeria-based adjuvants |
| EP2825195A4 (en) | 2012-03-12 | 2015-10-07 | Advaxis Inc | INHIBITION OF SUPPRESSOR CELL FUNCTION AFTER TREATMENT WITH A LISTERIAL VACCINE |
| MX2016010791A (es) | 2014-02-18 | 2017-04-27 | Advaxis Inc | Inmunoterapia con multiples objetivos dirigida por biomarcadores. |
| MA39717A (fr) * | 2014-03-05 | 2017-01-11 | Advaxis Inc | Procédés et compositions pour accroître le rapport des lymphocytes t effecteurs aux lymphocytes t régulateurs |
| MA39849A (fr) * | 2014-04-24 | 2017-03-01 | Advaxis Inc | Souches de listeria utilisées comme vaccin recombinant et procédé de production |
| US20160228530A1 (en) * | 2014-10-14 | 2016-08-11 | The Trustees Of The University Of Pennsylvania | Combination therapy for use in cancer therapy |
| MA41644A (fr) | 2015-03-03 | 2018-01-09 | Advaxis Inc | Compositions à base de listeria comprenant un système d'expression de minigènes codant pour des peptides, et leurs procédés d'utilisation |
| EP3313376A2 (en) * | 2015-06-26 | 2018-05-02 | Bayer Animal Health GmbH | Methods of modulating cytosolic dna surveillance molecules |
| CN108138123A (zh) * | 2015-09-02 | 2018-06-08 | 加利福尼亚大学董事会 | 用于调节李斯特菌属某些种中prfa介导的毒力基因活化的方法和组合物 |
| HK1258860A1 (zh) * | 2015-09-15 | 2019-11-22 | Advaxis, Inc. | 含有重组李斯特氏菌株的免疫治疗制剂的制作方法 |
| MX2019005685A (es) | 2016-11-30 | 2019-09-04 | Advaxis Inc | Composiciones inmunogenicas contra mutaciones de cancer recurrentes y metodos de uso de las mismas. |
| KR102748132B1 (ko) | 2017-09-19 | 2025-01-02 | 어드박시스, 인크. | 박테리아 또는 리스테리아 균주의 동결건조를 위한 조성물 및 방법 |
| CN111349645B (zh) * | 2018-12-24 | 2022-05-17 | 上海若泰医药科技有限公司 | 一种提高非整合减毒李斯特菌疫苗安全性的方法 |
| KR102052108B1 (ko) * | 2019-08-16 | 2019-12-04 | 주식회사 쎌바이오텍 | 영양요구성 마커를 포함하는 재조합 플라스미드, 이를 포함하는 항암 약물 위장관 전달용 미생물 및 그를 포함하는 항암 약제학적 조성물 |
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| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
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| US6855320B2 (en) | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
| JP2004500405A (ja) | 2000-03-29 | 2004-01-08 | ザ トラスティーズ オブ ザ ユニバーシティー オブ ペンシルヴァニア | 抗原の免疫原性を増強するための組成物および方法 |
| TWI221854B (en) | 2000-05-26 | 2004-10-11 | Anawrahta Biotech Co Ltd | Lac shuttle vectors, kit for expression of a heterologous gene and DNA vaccine carrier containing the same |
| JP2002253253A (ja) | 2001-03-01 | 2002-09-10 | Toyobo Co Ltd | 新規ｄｎａ断片及びグラム陰性細菌用新規ベクター |
| JP2002253212A (ja) | 2001-03-02 | 2002-09-10 | Yamaguchi Technology Licensing Organization Ltd | 有用酵母の栄養要求性変異株とその育種方法 |
| DE50103240D1 (de) | 2001-09-05 | 2004-09-16 | Ferro Gmbh | Strahlenhärtbares Edelmetallpräparat, dieses enthaltende Abziehbilder und Verfahren zum Dekorieren |
| US7425449B2 (en) | 2002-04-30 | 2008-09-16 | The Regents Of The University Of California | Site specific Listeria integration vectors and methods for using the same |
| GB0211459D0 (en) | 2002-05-18 | 2002-06-26 | Cobra Therapeutics Ltd | Plasmid stabilisation in vivo |
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| ES2684749T3 (es) | 2004-08-13 | 2018-10-04 | The Trustees Of The University Of Pennsylvania | Métodos para construir vacunas sin resistencia a antibióticos |
| US7855064B2 (en) * | 2004-08-13 | 2010-12-21 | The Trustees Of The University Of Pennsylvania | Antibiotic resistance free vaccines and methods for constructing and using same |
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2005
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- 2005-08-15 US US11/203,415 patent/US8906664B2/en active Active - Reinstated
- 2005-08-15 ES ES05808671.1T patent/ES2543079T3/es not_active Expired - Lifetime
- 2005-08-15 AU AU2005271246A patent/AU2005271246A1/en not_active Abandoned
- 2005-08-15 EP EP05808671.1A patent/EP1789559B1/en not_active Expired - Lifetime
- 2005-08-15 WO PCT/US2005/028895 patent/WO2006017856A2/en not_active Ceased
- 2005-08-15 CA CA002577306A patent/CA2577306A1/en not_active Abandoned
- 2005-08-15 PT PT15167706T patent/PT2942391T/pt unknown
- 2005-08-15 EP EP15167706.9A patent/EP2942391B1/en not_active Expired - Lifetime
- 2005-08-15 DK DK05808671.1T patent/DK1789559T3/en active
- 2005-08-15 DK DK15167706.9T patent/DK2942391T3/en active
- 2005-08-15 JP JP2007525861A patent/JP5530065B2/ja not_active Expired - Fee Related
- 2005-08-15 PT PT58086711T patent/PT1789559E/pt unknown
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2016
- 2016-10-18 US US15/296,973 patent/US9700608B2/en not_active Expired - Lifetime
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2017
- 2017-06-13 US US15/621,411 patent/US10426823B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2684749T3 (es) | 2018-10-04 |
| US20170281691A1 (en) | 2017-10-05 |
| EP2942391B1 (en) | 2018-05-23 |
| HK1217108A1 (en) | 2016-12-23 |
| US9700608B2 (en) | 2017-07-11 |
| DK1789559T3 (en) | 2015-08-24 |
| US8906664B2 (en) | 2014-12-09 |
| JP5530065B2 (ja) | 2014-06-25 |
| ES2543079T3 (es) | 2015-08-14 |
| US9492527B2 (en) | 2016-11-15 |
| US20170028045A1 (en) | 2017-02-02 |
| EP1789559B1 (en) | 2015-05-20 |
| US20150125480A1 (en) | 2015-05-07 |
| EP1789559A4 (en) | 2009-02-11 |
| EP1789559A2 (en) | 2007-05-30 |
| EP2942391A1 (en) | 2015-11-11 |
| US10426823B2 (en) | 2019-10-01 |
| DK2942391T3 (en) | 2018-08-27 |
| US20060104991A1 (en) | 2006-05-18 |
| JP2008509677A (ja) | 2008-04-03 |
| WO2006017856A3 (en) | 2006-08-31 |
| PT1789559E (pt) | 2015-10-09 |
| PT2942391T (pt) | 2018-10-09 |
| WO2006017856A2 (en) | 2006-02-16 |
| AU2005271246A1 (en) | 2006-02-16 |
| WO2006017856A9 (en) | 2006-10-19 |
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