DK1759013T3 - Identificering af overflade-associerede antigener til tumordiagnose - Google Patents

Identificering af overflade-associerede antigener til tumordiagnose

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Publication number
DK1759013T3
DK1759013T3 DK05747772.1T DK05747772T DK1759013T3 DK 1759013 T3 DK1759013 T3 DK 1759013T3 DK 05747772 T DK05747772 T DK 05747772T DK 1759013 T3 DK1759013 T3 DK 1759013T3
Authority
DK
Denmark
Prior art keywords
cells
expression
tumor
patient
nucleic acid
Prior art date
Application number
DK05747772.1T
Other languages
English (en)
Inventor
Philippe Thiel
Oezlem Tuereci
Ugur Sahin
Sandra Schneider
Gerd Helftenbein
Dirk Usener
Volker Schlueter
Michael Koslowski
Original Assignee
Ganymed Pharmaceuticals Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ganymed Pharmaceuticals Ag filed Critical Ganymed Pharmaceuticals Ag
Application granted granted Critical
Publication of DK1759013T3 publication Critical patent/DK1759013T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
DK05747772.1T 2004-05-11 2005-05-11 Identificering af overflade-associerede antigener til tumordiagnose DK1759013T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004023187A DE102004023187A1 (de) 2004-05-11 2004-05-11 Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
PCT/EP2005/005104 WO2005110338A2 (de) 2004-05-11 2005-05-11 Identifizierung von oberflächen-assoziierten antigenen für die tumordiagnose und -therapie

Publications (1)

Publication Number Publication Date
DK1759013T3 true DK1759013T3 (da) 2010-08-30

Family

ID=35064875

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05747772.1T DK1759013T3 (da) 2004-05-11 2005-05-11 Identificering af overflade-associerede antigener til tumordiagnose

Country Status (14)

Country Link
US (5) US7785801B2 (da)
EP (18) EP2258867A3 (da)
JP (6) JP2007537197A (da)
AT (1) ATE468409T1 (da)
AU (1) AU2005244425B2 (da)
CA (2) CA2820168C (da)
DE (2) DE102004023187A1 (da)
DK (1) DK1759013T3 (da)
ES (1) ES2346067T3 (da)
HR (1) HRP20100412T1 (da)
PL (1) PL1759013T3 (da)
PT (1) PT1759013E (da)
SI (1) SI1759013T1 (da)
WO (1) WO2005110338A2 (da)

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Publication number Publication date
US10724103B2 (en) 2020-07-28
EP2348135A2 (de) 2011-07-27
JP2007537197A (ja) 2007-12-20
CA2563671A1 (en) 2005-11-24
EP2267158A3 (de) 2011-04-06
JP2013032381A (ja) 2013-02-14
DE102004023187A1 (de) 2005-12-01
EP2280082A3 (de) 2011-05-18
EP2267156A3 (de) 2011-04-20
EP2280082A2 (de) 2011-02-02
JP2015083576A (ja) 2015-04-30
EP2287337A3 (de) 2011-04-20
EP2290103A2 (de) 2011-03-02
JP2016179986A (ja) 2016-10-13
US20140120085A1 (en) 2014-05-01
EP2239340A3 (de) 2010-11-17
EP2267157A3 (de) 2011-05-11
EP2280082B1 (de) 2016-08-10
PL1759013T3 (pl) 2010-10-29
EP2290104A3 (de) 2011-06-22
EP2258868A3 (de) 2011-04-06
EP2290104A2 (de) 2011-03-02
US20110014628A1 (en) 2011-01-20
EP2275572A2 (de) 2011-01-19
EP3382036A1 (de) 2018-10-03
WO2005110338A3 (de) 2006-06-29
CA2820168C (en) 2019-08-20
JP2012077085A (ja) 2012-04-19
EP2258869A3 (de) 2011-04-06
AU2005244425B2 (en) 2011-10-13
EP2258867A2 (de) 2010-12-08
EP2258869A2 (de) 2010-12-08
EP2239340A2 (de) 2010-10-13
EP2270209A3 (de) 2011-04-20
US20160193335A1 (en) 2016-07-07
EP2275570A2 (de) 2011-01-19
US20080193454A1 (en) 2008-08-14
EP1759013A2 (de) 2007-03-07
EP2290103A3 (de) 2011-06-22
US7785801B2 (en) 2010-08-31
EP2287337A2 (de) 2011-02-23
JP5732369B2 (ja) 2015-06-10
AU2005244425A1 (en) 2005-11-24
EP2258867A3 (de) 2011-04-06
PT1759013E (pt) 2010-08-17
JP2018104464A (ja) 2018-07-05
ES2346067T3 (es) 2010-10-08
DE502005009602D1 (de) 2010-07-01
EP2270209A2 (de) 2011-01-05
EP1759013B1 (de) 2010-05-19
EP2275571A2 (de) 2011-01-19
EP2258868A2 (de) 2010-12-08
EP2267157A2 (de) 2010-12-29
ATE468409T1 (de) 2010-06-15
SI1759013T1 (sl) 2010-09-30
EP2275570A3 (de) 2011-06-22
EP2275572A3 (de) 2011-05-11
JP5796003B2 (ja) 2015-10-21
EP2275571A3 (de) 2012-11-21
EP2267158A2 (de) 2010-12-29
US9533043B2 (en) 2017-01-03
HRP20100412T1 (hr) 2010-09-30
JP6434444B2 (ja) 2018-12-05
US9255131B2 (en) 2016-02-09
CA2820168A1 (en) 2005-11-24
EP2348135A3 (de) 2011-10-19
US20180169236A1 (en) 2018-06-21
WO2005110338A2 (de) 2005-11-24
EP2267156A2 (de) 2010-12-29

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