JP2008541776A5 - - Google Patents
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- Publication number
- JP2008541776A5 JP2008541776A5 JP2008515292A JP2008515292A JP2008541776A5 JP 2008541776 A5 JP2008541776 A5 JP 2008541776A5 JP 2008515292 A JP2008515292 A JP 2008515292A JP 2008515292 A JP2008515292 A JP 2008515292A JP 2008541776 A5 JP2008541776 A5 JP 2008541776A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- scaffold protein
- acid sequence
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 17
- 101710167800 Capsid assembly scaffolding protein Proteins 0.000 claims 10
- 101710130420 Probable capsid assembly scaffolding protein Proteins 0.000 claims 10
- 101710204410 Scaffold protein Proteins 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 9
- 229920001184 polypeptide Polymers 0.000 claims 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 230000035772 mutation Effects 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102220591835 Charged multivesicular body protein 3_V48D_mutation Human genes 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 102220237123 rs74315443 Human genes 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 206010017533 Fungal infection Diseases 0.000 claims 1
- 101000921786 Homo sapiens Cystatin-A Proteins 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 102000045247 human CSTA Human genes 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 108091008146 restriction endonucleases Proteins 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0511873A GB0511873D0 (en) | 2005-06-10 | 2005-06-10 | Scaffold |
| GB0511873.2 | 2005-06-10 | ||
| GB0608836A GB0608836D0 (en) | 2006-05-04 | 2006-05-04 | Scaffold |
| GB0608836.3 | 2006-05-04 | ||
| PCT/GB2006/002115 WO2006131749A2 (en) | 2005-06-10 | 2006-06-08 | Scaffold |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008541776A JP2008541776A (ja) | 2008-11-27 |
| JP2008541776A5 true JP2008541776A5 (enExample) | 2009-10-22 |
| JP4989638B2 JP4989638B2 (ja) | 2012-08-01 |
Family
ID=37314237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008515292A Active JP4989638B2 (ja) | 2005-06-10 | 2006-06-08 | 足場 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8063019B2 (enExample) |
| EP (1) | EP1904529B1 (enExample) |
| JP (1) | JP4989638B2 (enExample) |
| AT (1) | ATE477272T1 (enExample) |
| AU (1) | AU2006256530B2 (enExample) |
| CA (1) | CA2610976C (enExample) |
| DE (1) | DE602006016133D1 (enExample) |
| DK (1) | DK1904529T3 (enExample) |
| WO (1) | WO2006131749A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8063019B2 (en) * | 2005-06-10 | 2011-11-22 | Medical Research Council | Scaffold polypeptides for heterologous peptide display |
| GB0807065D0 (en) * | 2008-04-18 | 2008-05-21 | Univ Leeds | Novel scaffolds |
| GB201302597D0 (en) | 2013-02-14 | 2013-04-03 | Univ Leeds | Novel Synthetic Proteins |
| US10562946B2 (en) | 2014-06-20 | 2020-02-18 | Genentech, Inc. | Chagasin-based scaffold compositions, methods, and uses |
| WO2017127750A1 (en) | 2016-01-22 | 2017-07-27 | Modernatx, Inc. | Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof |
| CA3048486A1 (en) | 2017-01-04 | 2018-07-12 | Complete Genomics, Inc. | Stepwise sequencing by non-labeled reversible terminators or natural nucleotides |
| EP3574326B1 (en) | 2017-05-19 | 2025-03-19 | Philip Morris Products S.A. | Diagnostic test for distinguishing the smoking status of a subject |
| GB201710973D0 (en) | 2017-07-07 | 2017-08-23 | Avacta Life Sciences Ltd | Scaffold proteins |
| NZ788210A (en) * | 2019-10-16 | 2025-11-28 | Lg Chemical Ltd | Neonatal fc receptor binding affimers |
| GB202101299D0 (en) | 2020-06-09 | 2021-03-17 | Avacta Life Sciences Ltd | Diagnostic polypetides and methods |
| CN116783302A (zh) | 2020-10-09 | 2023-09-19 | 深圳华大基因科技有限公司 | 用于基于生物发光的测序的方法和组合物 |
| WO2023182945A2 (en) * | 2022-03-24 | 2023-09-28 | Agency For Science, Technology And Research | Engineering peptides using peptide epitope linker evolution |
| WO2024141788A1 (en) * | 2022-12-29 | 2024-07-04 | Affyxell Therapeutics Co., Ltd. | Genetically modified stem cells expressing exogenous binding agents and uses thereof |
| GB202403780D0 (en) | 2024-03-15 | 2024-05-01 | Avacta Life Sciences Ltd | Polypeptides and methods for detecting and quantifying small molecules |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1231274A3 (en) * | 1994-11-21 | 2002-10-09 | The University Of Leeds | Modified porteinase inhibitors |
| JP2002521652A (ja) * | 1998-07-20 | 2002-07-16 | ファーメクサ エイ／エス | リガンドおよびターゲット生体分子を同定するための新規な方法 |
| ATE530560T1 (de) | 2003-11-06 | 2011-11-15 | Danisco Us Inc | Vegf bindende und geträgerte peptide zur behandlung von hautkrankheiten |
| US8063019B2 (en) * | 2005-06-10 | 2011-11-22 | Medical Research Council | Scaffold polypeptides for heterologous peptide display |
-
2006
- 2006-06-08 US US11/917,057 patent/US8063019B2/en active Active
- 2006-06-08 WO PCT/GB2006/002115 patent/WO2006131749A2/en not_active Ceased
- 2006-06-08 DE DE602006016133T patent/DE602006016133D1/de active Active
- 2006-06-08 AT AT06744166T patent/ATE477272T1/de active
- 2006-06-08 AU AU2006256530A patent/AU2006256530B2/en not_active Ceased
- 2006-06-08 DK DK06744166.7T patent/DK1904529T3/da active
- 2006-06-08 JP JP2008515292A patent/JP4989638B2/ja active Active
- 2006-06-08 EP EP06744166A patent/EP1904529B1/en active Active
- 2006-06-08 CA CA2610976A patent/CA2610976C/en active Active
-
2011
- 2011-09-23 US US13/243,318 patent/US8481491B2/en not_active Expired - Fee Related
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