AU2006256530B2 - Scaffold - Google Patents

Scaffold Download PDF

Info

Publication number
AU2006256530B2
AU2006256530B2 AU2006256530A AU2006256530A AU2006256530B2 AU 2006256530 B2 AU2006256530 B2 AU 2006256530B2 AU 2006256530 A AU2006256530 A AU 2006256530A AU 2006256530 A AU2006256530 A AU 2006256530A AU 2006256530 B2 AU2006256530 B2 AU 2006256530B2
Authority
AU
Australia
Prior art keywords
peptide
scaffold
protein
stm
stefin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006256530A
Other languages
English (en)
Other versions
AU2006256530A1 (en
Inventor
Paul Ko Ferrigno
Sophie Laurenson
Robbie Woodman
Johannes Tsung-Han Yeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United Kingdom Research and Innovation
Original Assignee
United Kingdom Research and Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0511873A external-priority patent/GB0511873D0/en
Priority claimed from GB0608836A external-priority patent/GB0608836D0/en
Application filed by United Kingdom Research and Innovation filed Critical United Kingdom Research and Innovation
Publication of AU2006256530A1 publication Critical patent/AU2006256530A1/en
Application granted granted Critical
Publication of AU2006256530B2 publication Critical patent/AU2006256530B2/en
Assigned to UNITED KINGDOM RESEARCH AND INNOVATION reassignment UNITED KINGDOM RESEARCH AND INNOVATION Request for Assignment Assignors: MEDICAL RESEARCH COUNCIL
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2006256530A 2005-06-10 2006-06-08 Scaffold Ceased AU2006256530B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0511873A GB0511873D0 (en) 2005-06-10 2005-06-10 Scaffold
GB0511873.2 2005-06-10
GB0608836A GB0608836D0 (en) 2006-05-04 2006-05-04 Scaffold
GB0608836.3 2006-05-04
PCT/GB2006/002115 WO2006131749A2 (en) 2005-06-10 2006-06-08 Scaffold

Publications (2)

Publication Number Publication Date
AU2006256530A1 AU2006256530A1 (en) 2006-12-14
AU2006256530B2 true AU2006256530B2 (en) 2012-12-20

Family

ID=37314237

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006256530A Ceased AU2006256530B2 (en) 2005-06-10 2006-06-08 Scaffold

Country Status (9)

Country Link
US (2) US8063019B2 (enExample)
EP (1) EP1904529B1 (enExample)
JP (1) JP4989638B2 (enExample)
AT (1) ATE477272T1 (enExample)
AU (1) AU2006256530B2 (enExample)
CA (1) CA2610976C (enExample)
DE (1) DE602006016133D1 (enExample)
DK (1) DK1904529T3 (enExample)
WO (1) WO2006131749A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE477272T1 (de) * 2005-06-10 2010-08-15 Medical Res Council Verwendung von stefin a als gerüstprotein
GB0807065D0 (en) * 2008-04-18 2008-05-21 Univ Leeds Novel scaffolds
GB201302597D0 (en) 2013-02-14 2013-04-03 Univ Leeds Novel Synthetic Proteins
CN106573961B (zh) 2014-06-20 2022-01-04 豪夫迈·罗氏有限公司 基于chagasin的支架组合物、方法和应用
EP3405579A1 (en) 2016-01-22 2018-11-28 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
FI4112741T3 (fi) 2017-01-04 2025-05-15 Mgi Tech Co Ltd Vaiheittainen sekvensointi ei-leimatuilla, reversiibeleillä terminaattoreilla tai luonnollisilla nukleotideilla
WO2018211126A1 (en) 2017-05-19 2018-11-22 Philip Morris Products S.A. Diagnostic test for distinguishing the smoking status of a subject
GB201710973D0 (en) * 2017-07-07 2017-08-23 Avacta Life Sciences Ltd Scaffold proteins
AU2020367510B2 (en) * 2019-10-16 2025-06-26 Lg Chem, Ltd. Neonatal Fc receptor binding AFFIMERs
GB202101299D0 (en) 2020-06-09 2021-03-17 Avacta Life Sciences Ltd Diagnostic polypetides and methods
CN116783302A (zh) 2020-10-09 2023-09-19 深圳华大基因科技有限公司 用于基于生物发光的测序的方法和组合物
WO2023153876A1 (ko) * 2022-02-10 2023-08-17 주식회사 아피셀테라퓨틱스 Cd40l에 특이적으로 결합하는 스테핀 a 단백질 변이체 및 이의 용도
WO2023182945A2 (en) * 2022-03-24 2023-09-28 Agency For Science, Technology And Research Engineering peptides using peptide epitope linker evolution
US20260022343A1 (en) * 2022-12-29 2026-01-22 Affyxell Therapeutics Co., Ltd. Genetically modified cells comprising a nucleic acid encoding a cd40l binding agent and uses thereof
GB202403780D0 (en) 2024-03-15 2024-05-01 Avacta Life Sciences Ltd Polypeptides and methods for detecting and quantifying small molecules

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000005406A1 (en) * 1998-07-20 2000-02-03 M & E Biotech A/S Novel methods for the identification of ligand and target biomolecules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996016173A2 (en) * 1994-11-21 1996-05-30 The University Of Leeds Modified proteinase inhibitors
CA2544820C (en) * 2003-11-06 2014-02-18 Genencor International, Inc. Bacterial expression of protease inhibitors and variants thereof
ATE477272T1 (de) * 2005-06-10 2010-08-15 Medical Res Council Verwendung von stefin a als gerüstprotein

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000005406A1 (en) * 1998-07-20 2000-02-03 M & E Biotech A/S Novel methods for the identification of ligand and target biomolecules

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Database EMBL Accession No. X05978, "Human Radiated Keratinocyte mRNA for Cysteine Protease Inhibitor". 1988, [Online]. *

Also Published As

Publication number Publication date
EP1904529B1 (en) 2010-08-11
EP1904529A2 (en) 2008-04-02
US20080207509A1 (en) 2008-08-28
WO2006131749A2 (en) 2006-12-14
US8063019B2 (en) 2011-11-22
DE602006016133D1 (de) 2010-09-23
US20120190819A1 (en) 2012-07-26
CA2610976C (en) 2020-11-24
AU2006256530A1 (en) 2006-12-14
CA2610976A1 (en) 2006-12-14
JP2008541776A (ja) 2008-11-27
US8481491B2 (en) 2013-07-09
WO2006131749A3 (en) 2007-05-18
ATE477272T1 (de) 2010-08-15
JP4989638B2 (ja) 2012-08-01
DK1904529T3 (da) 2010-11-15

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: UNITED KINGDOM RESEARCH AND INNOVATION

Free format text: FORMER OWNER(S): MEDICAL RESEARCH COUNCIL

MK14 Patent ceased section 143(a) (annual fees not paid) or expired