AU2006256530B2 - Scaffold - Google Patents

Scaffold Download PDF

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Publication number
AU2006256530B2
AU2006256530B2 AU2006256530A AU2006256530A AU2006256530B2 AU 2006256530 B2 AU2006256530 B2 AU 2006256530B2 AU 2006256530 A AU2006256530 A AU 2006256530A AU 2006256530 A AU2006256530 A AU 2006256530A AU 2006256530 B2 AU2006256530 B2 AU 2006256530B2
Authority
AU
Australia
Prior art keywords
peptide
scaffold
protein
stm
stefin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006256530A
Other languages
English (en)
Other versions
AU2006256530A1 (en
Inventor
Paul Ko Ferrigno
Sophie Laurenson
Robbie Woodman
Johannes Tsung-Han Yeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United Kingdom Research and Innovation
Original Assignee
United Kingdom Research and Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0511873A external-priority patent/GB0511873D0/en
Priority claimed from GB0608836A external-priority patent/GB0608836D0/en
Application filed by United Kingdom Research and Innovation filed Critical United Kingdom Research and Innovation
Publication of AU2006256530A1 publication Critical patent/AU2006256530A1/en
Application granted granted Critical
Publication of AU2006256530B2 publication Critical patent/AU2006256530B2/en
Assigned to UNITED KINGDOM RESEARCH AND INNOVATION reassignment UNITED KINGDOM RESEARCH AND INNOVATION Request for Assignment Assignors: MEDICAL RESEARCH COUNCIL
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2006256530A 2005-06-10 2006-06-08 Scaffold Ceased AU2006256530B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0511873A GB0511873D0 (en) 2005-06-10 2005-06-10 Scaffold
GB0511873.2 2005-06-10
GB0608836A GB0608836D0 (en) 2006-05-04 2006-05-04 Scaffold
GB0608836.3 2006-05-04
PCT/GB2006/002115 WO2006131749A2 (en) 2005-06-10 2006-06-08 Scaffold

Publications (2)

Publication Number Publication Date
AU2006256530A1 AU2006256530A1 (en) 2006-12-14
AU2006256530B2 true AU2006256530B2 (en) 2012-12-20

Family

ID=37314237

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006256530A Ceased AU2006256530B2 (en) 2005-06-10 2006-06-08 Scaffold

Country Status (9)

Country Link
US (2) US8063019B2 (enExample)
EP (1) EP1904529B1 (enExample)
JP (1) JP4989638B2 (enExample)
AT (1) ATE477272T1 (enExample)
AU (1) AU2006256530B2 (enExample)
CA (1) CA2610976C (enExample)
DE (1) DE602006016133D1 (enExample)
DK (1) DK1904529T3 (enExample)
WO (1) WO2006131749A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8063019B2 (en) * 2005-06-10 2011-11-22 Medical Research Council Scaffold polypeptides for heterologous peptide display
GB0807065D0 (en) * 2008-04-18 2008-05-21 Univ Leeds Novel scaffolds
GB201302597D0 (en) 2013-02-14 2013-04-03 Univ Leeds Novel Synthetic Proteins
US10562946B2 (en) 2014-06-20 2020-02-18 Genentech, Inc. Chagasin-based scaffold compositions, methods, and uses
WO2017127750A1 (en) 2016-01-22 2017-07-27 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
CA3048486A1 (en) 2017-01-04 2018-07-12 Complete Genomics, Inc. Stepwise sequencing by non-labeled reversible terminators or natural nucleotides
EP3574326B1 (en) 2017-05-19 2025-03-19 Philip Morris Products S.A. Diagnostic test for distinguishing the smoking status of a subject
GB201710973D0 (en) 2017-07-07 2017-08-23 Avacta Life Sciences Ltd Scaffold proteins
NZ788210A (en) * 2019-10-16 2025-11-28 Lg Chemical Ltd Neonatal fc receptor binding affimers
GB202101299D0 (en) 2020-06-09 2021-03-17 Avacta Life Sciences Ltd Diagnostic polypetides and methods
CN116783302A (zh) 2020-10-09 2023-09-19 深圳华大基因科技有限公司 用于基于生物发光的测序的方法和组合物
WO2023182945A2 (en) * 2022-03-24 2023-09-28 Agency For Science, Technology And Research Engineering peptides using peptide epitope linker evolution
WO2024141788A1 (en) * 2022-12-29 2024-07-04 Affyxell Therapeutics Co., Ltd. Genetically modified stem cells expressing exogenous binding agents and uses thereof
GB202403780D0 (en) 2024-03-15 2024-05-01 Avacta Life Sciences Ltd Polypeptides and methods for detecting and quantifying small molecules

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000005406A1 (en) * 1998-07-20 2000-02-03 M & E Biotech A/S Novel methods for the identification of ligand and target biomolecules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1231274A3 (en) * 1994-11-21 2002-10-09 The University Of Leeds Modified porteinase inhibitors
ATE530560T1 (de) 2003-11-06 2011-11-15 Danisco Us Inc Vegf bindende und geträgerte peptide zur behandlung von hautkrankheiten
US8063019B2 (en) * 2005-06-10 2011-11-22 Medical Research Council Scaffold polypeptides for heterologous peptide display

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000005406A1 (en) * 1998-07-20 2000-02-03 M & E Biotech A/S Novel methods for the identification of ligand and target biomolecules

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Database EMBL Accession No. X05978, "Human Radiated Keratinocyte mRNA for Cysteine Protease Inhibitor". 1988, [Online]. *

Also Published As

Publication number Publication date
CA2610976C (en) 2020-11-24
AU2006256530A1 (en) 2006-12-14
US8063019B2 (en) 2011-11-22
ATE477272T1 (de) 2010-08-15
DE602006016133D1 (de) 2010-09-23
US20080207509A1 (en) 2008-08-28
CA2610976A1 (en) 2006-12-14
WO2006131749A3 (en) 2007-05-18
DK1904529T3 (da) 2010-11-15
EP1904529B1 (en) 2010-08-11
US20120190819A1 (en) 2012-07-26
JP2008541776A (ja) 2008-11-27
EP1904529A2 (en) 2008-04-02
JP4989638B2 (ja) 2012-08-01
US8481491B2 (en) 2013-07-09
WO2006131749A2 (en) 2006-12-14

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: UNITED KINGDOM RESEARCH AND INNOVATION

Free format text: FORMER OWNER(S): MEDICAL RESEARCH COUNCIL