JP4989638B2 - 足場 - Google Patents

足場 Download PDF

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Publication number
JP4989638B2
JP4989638B2 JP2008515292A JP2008515292A JP4989638B2 JP 4989638 B2 JP4989638 B2 JP 4989638B2 JP 2008515292 A JP2008515292 A JP 2008515292A JP 2008515292 A JP2008515292 A JP 2008515292A JP 4989638 B2 JP4989638 B2 JP 4989638B2
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JP
Japan
Prior art keywords
peptide
stefin
scaffold
protein
stm
Prior art date
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Active
Application number
JP2008515292A
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English (en)
Japanese (ja)
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JP2008541776A5 (enExample
JP2008541776A (ja
Inventor
ロビー ウッドマン
ヨハネス ツンハン ヨ
ソフィー ローレンソン
フェリーニョ ポール コ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
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Medical Research Council
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Publication date
Priority claimed from GB0511873A external-priority patent/GB0511873D0/en
Priority claimed from GB0608836A external-priority patent/GB0608836D0/en
Application filed by Medical Research Council filed Critical Medical Research Council
Publication of JP2008541776A publication Critical patent/JP2008541776A/ja
Publication of JP2008541776A5 publication Critical patent/JP2008541776A5/ja
Application granted granted Critical
Publication of JP4989638B2 publication Critical patent/JP4989638B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2008515292A 2005-06-10 2006-06-08 足場 Active JP4989638B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0511873A GB0511873D0 (en) 2005-06-10 2005-06-10 Scaffold
GB0511873.2 2005-06-10
GB0608836A GB0608836D0 (en) 2006-05-04 2006-05-04 Scaffold
GB0608836.3 2006-05-04
PCT/GB2006/002115 WO2006131749A2 (en) 2005-06-10 2006-06-08 Scaffold

Publications (3)

Publication Number Publication Date
JP2008541776A JP2008541776A (ja) 2008-11-27
JP2008541776A5 JP2008541776A5 (enExample) 2009-10-22
JP4989638B2 true JP4989638B2 (ja) 2012-08-01

Family

ID=37314237

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008515292A Active JP4989638B2 (ja) 2005-06-10 2006-06-08 足場

Country Status (9)

Country Link
US (2) US8063019B2 (enExample)
EP (1) EP1904529B1 (enExample)
JP (1) JP4989638B2 (enExample)
AT (1) ATE477272T1 (enExample)
AU (1) AU2006256530B2 (enExample)
CA (1) CA2610976C (enExample)
DE (1) DE602006016133D1 (enExample)
DK (1) DK1904529T3 (enExample)
WO (1) WO2006131749A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8063019B2 (en) * 2005-06-10 2011-11-22 Medical Research Council Scaffold polypeptides for heterologous peptide display
GB0807065D0 (en) * 2008-04-18 2008-05-21 Univ Leeds Novel scaffolds
GB201302597D0 (en) 2013-02-14 2013-04-03 Univ Leeds Novel Synthetic Proteins
US10562946B2 (en) 2014-06-20 2020-02-18 Genentech, Inc. Chagasin-based scaffold compositions, methods, and uses
WO2017127750A1 (en) 2016-01-22 2017-07-27 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
CA3048486A1 (en) 2017-01-04 2018-07-12 Complete Genomics, Inc. Stepwise sequencing by non-labeled reversible terminators or natural nucleotides
EP3574326B1 (en) 2017-05-19 2025-03-19 Philip Morris Products S.A. Diagnostic test for distinguishing the smoking status of a subject
GB201710973D0 (en) 2017-07-07 2017-08-23 Avacta Life Sciences Ltd Scaffold proteins
NZ788210A (en) * 2019-10-16 2025-11-28 Lg Chemical Ltd Neonatal fc receptor binding affimers
GB202101299D0 (en) 2020-06-09 2021-03-17 Avacta Life Sciences Ltd Diagnostic polypetides and methods
CN116783302A (zh) 2020-10-09 2023-09-19 深圳华大基因科技有限公司 用于基于生物发光的测序的方法和组合物
WO2023182945A2 (en) * 2022-03-24 2023-09-28 Agency For Science, Technology And Research Engineering peptides using peptide epitope linker evolution
WO2024141788A1 (en) * 2022-12-29 2024-07-04 Affyxell Therapeutics Co., Ltd. Genetically modified stem cells expressing exogenous binding agents and uses thereof
GB202403780D0 (en) 2024-03-15 2024-05-01 Avacta Life Sciences Ltd Polypeptides and methods for detecting and quantifying small molecules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1231274A3 (en) * 1994-11-21 2002-10-09 The University Of Leeds Modified porteinase inhibitors
JP2002521652A (ja) * 1998-07-20 2002-07-16 ファーメクサ エイ／エス リガンドおよびターゲット生体分子を同定するための新規な方法
ATE530560T1 (de) 2003-11-06 2011-11-15 Danisco Us Inc Vegf bindende und geträgerte peptide zur behandlung von hautkrankheiten
US8063019B2 (en) * 2005-06-10 2011-11-22 Medical Research Council Scaffold polypeptides for heterologous peptide display

Also Published As

Publication number Publication date
CA2610976C (en) 2020-11-24
AU2006256530A1 (en) 2006-12-14
US8063019B2 (en) 2011-11-22
ATE477272T1 (de) 2010-08-15
DE602006016133D1 (de) 2010-09-23
US20080207509A1 (en) 2008-08-28
CA2610976A1 (en) 2006-12-14
WO2006131749A3 (en) 2007-05-18
DK1904529T3 (da) 2010-11-15
EP1904529B1 (en) 2010-08-11
US20120190819A1 (en) 2012-07-26
JP2008541776A (ja) 2008-11-27
EP1904529A2 (en) 2008-04-02
US8481491B2 (en) 2013-07-09
WO2006131749A2 (en) 2006-12-14
AU2006256530B2 (en) 2012-12-20

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