DK1904529T3 - Anvendelse af Stefin A som et scaffoldprotein - Google Patents

Anvendelse af Stefin A som et scaffoldprotein

Info

Publication number
DK1904529T3
DK1904529T3 DK06744166.7T DK06744166T DK1904529T3 DK 1904529 T3 DK1904529 T3 DK 1904529T3 DK 06744166 T DK06744166 T DK 06744166T DK 1904529 T3 DK1904529 T3 DK 1904529T3
Authority
DK
Denmark
Prior art keywords
stefin
scaffold
scaffold protein
mutations
relates
Prior art date
Application number
DK06744166.7T
Other languages
Danish (da)
English (en)
Inventor
Robbie Woodman
Johannes Tsung-Han Yeh
Sophie Laurenson
Ferrigno Paul Ko
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0511873A external-priority patent/GB0511873D0/en
Priority claimed from GB0608836A external-priority patent/GB0608836D0/en
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of DK1904529T3 publication Critical patent/DK1904529T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK06744166.7T 2005-06-10 2006-06-08 Anvendelse af Stefin A som et scaffoldprotein DK1904529T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0511873A GB0511873D0 (en) 2005-06-10 2005-06-10 Scaffold
GB0608836A GB0608836D0 (en) 2006-05-04 2006-05-04 Scaffold
PCT/GB2006/002115 WO2006131749A2 (en) 2005-06-10 2006-06-08 Scaffold

Publications (1)

Publication Number Publication Date
DK1904529T3 true DK1904529T3 (da) 2010-11-15

Family

ID=37314237

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06744166.7T DK1904529T3 (da) 2005-06-10 2006-06-08 Anvendelse af Stefin A som et scaffoldprotein

Country Status (9)

Country Link
US (2) US8063019B2 (enExample)
EP (1) EP1904529B1 (enExample)
JP (1) JP4989638B2 (enExample)
AT (1) ATE477272T1 (enExample)
AU (1) AU2006256530B2 (enExample)
CA (1) CA2610976C (enExample)
DE (1) DE602006016133D1 (enExample)
DK (1) DK1904529T3 (enExample)
WO (1) WO2006131749A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4989638B2 (ja) * 2005-06-10 2012-08-01 メディカル リサーチ カウンシル 足場
GB0807065D0 (en) * 2008-04-18 2008-05-21 Univ Leeds Novel scaffolds
GB201302597D0 (en) * 2013-02-14 2013-04-03 Univ Leeds Novel Synthetic Proteins
JP6655074B2 (ja) * 2014-06-20 2020-02-26 ジェネンテック， インコーポレイテッド シャガシンに基づく足場組成物、方法及び使用
EP3405579A1 (en) 2016-01-22 2018-11-28 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
CA3048486A1 (en) 2017-01-04 2018-07-12 Complete Genomics, Inc. Stepwise sequencing by non-labeled reversible terminators or natural nucleotides
EP3574326B1 (en) 2017-05-19 2025-03-19 Philip Morris Products S.A. Diagnostic test for distinguishing the smoking status of a subject
GB201710973D0 (en) 2017-07-07 2017-08-23 Avacta Life Sciences Ltd Scaffold proteins
NZ788210A (en) * 2019-10-16 2025-11-28 Lg Chemical Ltd Neonatal fc receptor binding affimers
GB202101299D0 (en) 2020-06-09 2021-03-17 Avacta Life Sciences Ltd Diagnostic polypetides and methods
WO2022073493A1 (en) 2020-10-09 2022-04-14 Bgi Shenzhen Co., Ltd. Methods and compositions for bioluminescence-based sequencing
WO2023153876A1 (ko) * 2022-02-10 2023-08-17 주식회사 아피셀테라퓨틱스 Cd40l에 특이적으로 결합하는 스테핀 a 단백질 변이체 및 이의 용도
WO2023182945A2 (en) * 2022-03-24 2023-09-28 Agency For Science, Technology And Research Engineering peptides using peptide epitope linker evolution
US20260022343A1 (en) * 2022-12-29 2026-01-22 Affyxell Therapeutics Co., Ltd. Genetically modified cells comprising a nucleic acid encoding a cd40l binding agent and uses thereof
GB202403780D0 (en) 2024-03-15 2024-05-01 Avacta Life Sciences Ltd Polypeptides and methods for detecting and quantifying small molecules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2182598C2 (ru) * 1994-11-21 2002-05-20 Новартис Аг Модифицированные ингибиторы протеиназы
ATE223971T1 (de) * 1998-07-20 2002-09-15 Inoxell As Neue methoden zum auffinden von liganden- und ziel-biomolekülen
CA2544820C (en) 2003-11-06 2014-02-18 Genencor International, Inc. Bacterial expression of protease inhibitors and variants thereof
JP4989638B2 (ja) * 2005-06-10 2012-08-01 メディカル リサーチ カウンシル 足場

Also Published As

Publication number Publication date
CA2610976A1 (en) 2006-12-14
AU2006256530A1 (en) 2006-12-14
US8063019B2 (en) 2011-11-22
EP1904529A2 (en) 2008-04-02
EP1904529B1 (en) 2010-08-11
US8481491B2 (en) 2013-07-09
DE602006016133D1 (de) 2010-09-23
JP4989638B2 (ja) 2012-08-01
CA2610976C (en) 2020-11-24
ATE477272T1 (de) 2010-08-15
JP2008541776A (ja) 2008-11-27
US20080207509A1 (en) 2008-08-28
WO2006131749A3 (en) 2007-05-18
WO2006131749A2 (en) 2006-12-14
AU2006256530B2 (en) 2012-12-20
US20120190819A1 (en) 2012-07-26

Similar Documents

Publication Publication Date Title
DK2071028T3 (da) HLA-DR-bindende antigenpeptid afledt af WT1
ATE477272T1 (de) Verwendung von stefin a als gerüstprotein
EA200700136A1 (ru) Анти-cd154-антитела
DK1844150T3 (da) Rekombinant ekspression af proteiner i en to-kædet form med disulfidbroer
DE602005020165D1 (de) Verfahren zur herstellung von l-arginin, l-ornithin oder l-citrullin
DE60035419D1 (de) Antigene peptide aus neisseria
DE50112802D1 (de) Peptide, deren herstellung und verwendung zur bindung von immunglobulinen
EA201100070A1 (ru) Туберкулезный белок rv2386c, композиции и их применения
ATE293169T1 (de) Latency associated peptide von tgf-beta um pharmazeutisch aktive proteine latent zu machen
DK1530637T3 (da) Carlsberg-subtilisin-proteiner med nedsat immunogenitet
DE60335726D1 (de) Chromoprotein und fluoroproteine
ATE323763T1 (de) Dna & protein bindende miniatur proteine
DE602004015142D1 (de) Antiangiogene peptide zur behandlung oder vorbeugung von endometriose
JP2008541776A5 (enExample)
WO2005044845A3 (en) Protein binding miniature proteins
ATE474589T1 (de) Angiogene peptide und ihre verwendungen
ATE503834T1 (de) Bibliotheken rekombinanter chimärischer proteine
ATE346091T1 (de) Neues diagnostisches reagens und kit zur erkennung von rickettsiose
EP1842911A4 (en) HLA BINDING PEPTIDES, FOR THOSE CODING DNA FRAGMENTS AND RECOMBINANT VECTORS
ATE466876T1 (de) Immunogene konstrukte
EP1757687A4 (en) HLA BINDING PEPTIDE, PRE-STEP, DNA DOMAGING AND RECOMBINANT VECTOR
ATE538806T1 (de) Peptide mit spezifischem sitz in herzgefässen und verwandte konjugate und verfahren
DK2186898T3 (da) Blomstrings-induktion
SG170757A1 (en) Polypeptide having esterase activity and recombinant esterase and use thereof
FI20031050A7 (fi) Menetelmä proteiinien katkaisuun