DK1904529T3 - Anvendelse af Stefin A som et scaffoldprotein - Google Patents

Anvendelse af Stefin A som et scaffoldprotein

Info

Publication number
DK1904529T3
DK1904529T3 DK06744166.7T DK06744166T DK1904529T3 DK 1904529 T3 DK1904529 T3 DK 1904529T3 DK 06744166 T DK06744166 T DK 06744166T DK 1904529 T3 DK1904529 T3 DK 1904529T3
Authority
DK
Denmark
Prior art keywords
stefin
scaffold
scaffold protein
mutations
relates
Prior art date
Application number
DK06744166.7T
Other languages
Danish (da)
English (en)
Inventor
Robbie Woodman
Johannes Tsung-Han Yeh
Sophie Laurenson
Ferrigno Paul Ko
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0511873A external-priority patent/GB0511873D0/en
Priority claimed from GB0608836A external-priority patent/GB0608836D0/en
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of DK1904529T3 publication Critical patent/DK1904529T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK06744166.7T 2005-06-10 2006-06-08 Anvendelse af Stefin A som et scaffoldprotein DK1904529T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0511873A GB0511873D0 (en) 2005-06-10 2005-06-10 Scaffold
GB0608836A GB0608836D0 (en) 2006-05-04 2006-05-04 Scaffold
PCT/GB2006/002115 WO2006131749A2 (en) 2005-06-10 2006-06-08 Scaffold

Publications (1)

Publication Number Publication Date
DK1904529T3 true DK1904529T3 (da) 2010-11-15

Family

ID=37314237

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06744166.7T DK1904529T3 (da) 2005-06-10 2006-06-08 Anvendelse af Stefin A som et scaffoldprotein

Country Status (9)

Country Link
US (2) US8063019B2 (enExample)
EP (1) EP1904529B1 (enExample)
JP (1) JP4989638B2 (enExample)
AT (1) ATE477272T1 (enExample)
AU (1) AU2006256530B2 (enExample)
CA (1) CA2610976C (enExample)
DE (1) DE602006016133D1 (enExample)
DK (1) DK1904529T3 (enExample)
WO (1) WO2006131749A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8063019B2 (en) * 2005-06-10 2011-11-22 Medical Research Council Scaffold polypeptides for heterologous peptide display
GB0807065D0 (en) * 2008-04-18 2008-05-21 Univ Leeds Novel scaffolds
GB201302597D0 (en) 2013-02-14 2013-04-03 Univ Leeds Novel Synthetic Proteins
US10562946B2 (en) 2014-06-20 2020-02-18 Genentech, Inc. Chagasin-based scaffold compositions, methods, and uses
WO2017127750A1 (en) 2016-01-22 2017-07-27 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
CA3048486A1 (en) 2017-01-04 2018-07-12 Complete Genomics, Inc. Stepwise sequencing by non-labeled reversible terminators or natural nucleotides
EP3574326B1 (en) 2017-05-19 2025-03-19 Philip Morris Products S.A. Diagnostic test for distinguishing the smoking status of a subject
GB201710973D0 (en) 2017-07-07 2017-08-23 Avacta Life Sciences Ltd Scaffold proteins
NZ788210A (en) * 2019-10-16 2025-11-28 Lg Chemical Ltd Neonatal fc receptor binding affimers
GB202101299D0 (en) 2020-06-09 2021-03-17 Avacta Life Sciences Ltd Diagnostic polypetides and methods
CN116783302A (zh) 2020-10-09 2023-09-19 深圳华大基因科技有限公司 用于基于生物发光的测序的方法和组合物
WO2023182945A2 (en) * 2022-03-24 2023-09-28 Agency For Science, Technology And Research Engineering peptides using peptide epitope linker evolution
WO2024141788A1 (en) * 2022-12-29 2024-07-04 Affyxell Therapeutics Co., Ltd. Genetically modified stem cells expressing exogenous binding agents and uses thereof
GB202403780D0 (en) 2024-03-15 2024-05-01 Avacta Life Sciences Ltd Polypeptides and methods for detecting and quantifying small molecules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1231274A3 (en) * 1994-11-21 2002-10-09 The University Of Leeds Modified porteinase inhibitors
JP2002521652A (ja) * 1998-07-20 2002-07-16 ファーメクサ エイ／エス リガンドおよびターゲット生体分子を同定するための新規な方法
ATE530560T1 (de) 2003-11-06 2011-11-15 Danisco Us Inc Vegf bindende und geträgerte peptide zur behandlung von hautkrankheiten
US8063019B2 (en) * 2005-06-10 2011-11-22 Medical Research Council Scaffold polypeptides for heterologous peptide display

Also Published As

Publication number Publication date
CA2610976C (en) 2020-11-24
AU2006256530A1 (en) 2006-12-14
US8063019B2 (en) 2011-11-22
ATE477272T1 (de) 2010-08-15
DE602006016133D1 (de) 2010-09-23
US20080207509A1 (en) 2008-08-28
CA2610976A1 (en) 2006-12-14
WO2006131749A3 (en) 2007-05-18
EP1904529B1 (en) 2010-08-11
US20120190819A1 (en) 2012-07-26
JP2008541776A (ja) 2008-11-27
EP1904529A2 (en) 2008-04-02
JP4989638B2 (ja) 2012-08-01
US8481491B2 (en) 2013-07-09
WO2006131749A2 (en) 2006-12-14
AU2006256530B2 (en) 2012-12-20

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