ATE503834T1 - Bibliotheken rekombinanter chimärischer proteine - Google Patents

Bibliotheken rekombinanter chimärischer proteine

Info

Publication number
ATE503834T1
ATE503834T1 AT04786588T AT04786588T ATE503834T1 AT E503834 T1 ATE503834 T1 AT E503834T1 AT 04786588 T AT04786588 T AT 04786588T AT 04786588 T AT04786588 T AT 04786588T AT E503834 T1 ATE503834 T1 AT E503834T1
Authority
AT
Austria
Prior art keywords
chimeric proteins
recombinant chimeric
libraries
amino acid
present
Prior art date
Application number
AT04786588T
Other languages
English (en)
Inventor
Gil Sharon
Abraham Laban
Original Assignee
Proterec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proterec Ltd filed Critical Proterec Ltd
Application granted granted Critical
Publication of ATE503834T1 publication Critical patent/ATE503834T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
AT04786588T 2003-08-27 2004-08-26 Bibliotheken rekombinanter chimärischer proteine ATE503834T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49792403P 2003-08-27 2003-08-27
PCT/US2004/027793 WO2005021719A2 (en) 2003-08-27 2004-08-26 Libraries of recombinant chimeric proteins
US10/926,542 US20050053989A1 (en) 2003-08-27 2004-08-26 Libraries of recombinant chimeric proteins

Publications (1)

Publication Number Publication Date
ATE503834T1 true ATE503834T1 (de) 2011-04-15

Family

ID=34228622

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04786588T ATE503834T1 (de) 2003-08-27 2004-08-26 Bibliotheken rekombinanter chimärischer proteine

Country Status (6)

Country Link
US (1) US20050053989A1 (de)
EP (2) EP1670932B1 (de)
AT (1) ATE503834T1 (de)
DE (1) DE602004032042D1 (de)
IL (1) IL173954A0 (de)
WO (1) WO2005021719A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100069264A1 (en) * 2003-08-27 2010-03-18 Gil Sharon Libraries of recombinant chimeric proteins
AU2013201171B2 (en) * 2006-02-13 2016-01-21 Monsanto Technology Llc Plant chimeric binding polypeptides for universal molecular recognition
AU2015203464B2 (en) * 2006-02-13 2017-08-10 Monsanto Technology Llc Plant chimeric binding polypeptides for universal molecular recognition
AR059448A1 (es) * 2006-02-13 2008-04-09 Divergence Inc Polipeptidos quimericos vegetales de union para el reconocimiento molecular universal
WO2011025826A1 (en) * 2009-08-26 2011-03-03 Research Development Foundation Methods for creating antibody libraries
DK2989203T3 (da) 2013-04-23 2020-02-17 The Univ Court Of The Univ Of Aberdeen Syntetisk bibliotek for specifikke bindingsmolekyler
CA2965485A1 (en) * 2014-10-21 2016-04-28 Martin R. Schiller Methods and compositions for screening molecular function comprising chimeric minimotifs

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US6107059A (en) * 1992-04-29 2000-08-22 Affymax Technologies N.V. Peptide library and screening method
US6335160B1 (en) * 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6165793A (en) * 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6117679A (en) * 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6489145B1 (en) * 1996-07-09 2002-12-03 Diversa Corporation Method of DNA shuffling
US6537776B1 (en) * 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
GB9701425D0 (en) * 1997-01-24 1997-03-12 Bioinvent Int Ab A method for in vitro molecular evolution of protein function
IL120339A0 (en) * 1997-02-27 1997-06-10 Gesher Israel Advanced Biotecs Improved DNA assembly method
AU5347999A (en) * 1998-08-12 2000-03-06 Maxygen, Inc. Dna shuffling of monooxygenase genes for production of industrial chemicals
US6376246B1 (en) * 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
EP1144616B2 (de) 1999-01-19 2009-01-14 Unilever Plc Verfahren zur herstellung von antikörperfragmenten
GB0008419D0 (en) 2000-04-05 2000-05-24 Bioinvent Int Ab A method for invitro molecular evolution of antibody function
ATE384129T1 (de) * 2001-11-22 2008-02-15 Univ Keio Künstliche antikörperbibliothek mit super- repertoire
US20060141626A1 (en) * 2004-10-27 2006-06-29 Monsanto Technology Llc Non-random method of gene shuffling

Also Published As

Publication number Publication date
EP2261332A3 (de) 2012-05-09
WO2005021719A3 (en) 2006-05-04
EP1670932B1 (de) 2011-03-30
DE602004032042D1 (de) 2011-05-12
US20050053989A1 (en) 2005-03-10
EP1670932A4 (de) 2008-05-28
EP1670932A2 (de) 2006-06-21
IL173954A0 (en) 2006-07-05
WO2005021719A2 (en) 2005-03-10
EP2261332A2 (de) 2010-12-15

Similar Documents

Publication Publication Date Title
ATE488586T1 (de) In vitro peptid-expressionsbank
ATE543506T1 (de) Methode zur stabilisierung von proteinen
NZ591415A (en) Haemophilus influenzae type B
IL173954A0 (en) Libraries of recombinant chimeric proteins and methods of generating the same
IL173952A0 (en) Anti-angiogenic peptides and pharmaceutical compositions based thereon
DE602006016133D1 (de) Verwendung von stefin a als gerüstprotein
ATE293169T1 (de) Latency associated peptide von tgf-beta um pharmazeutisch aktive proteine latent zu machen
ATE543833T1 (de) Bmp-7-varianten-zusammensetzungen, verfahren und verwendungen
ATE417618T1 (de) Faktor-viii-polypeptide auf hohem expressionsniveau codierende nukleinsäure- und aminosäuresequenzen und verwendungsverfahren
WO2006047728A3 (en) Bmp gene and fusion protein
ATE370159T1 (de) Streptavidin-bindungspeptid
ATE435916T1 (de) Rekombinantes pockenvirus für chimäre proteine des menschlichen immunschwächevirus
DE602004032345D1 (de) Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen
FI20050753A (fi) Uudet peptidit
DK1387854T3 (da) SFRP og peptidmotiver som interagerer med SFRP og fremgangsmåder til anvendelse deraf
WO2003082897A3 (en) Synthetic active peptide fragments
DE60037413D1 (de) Rekombinante adhesin-proteine aus haemophilus influenzae
MXPA05009954A (es) Familia de proteinas secretadas.
DK2186898T3 (da) Blomstrings-induktion
WO2004053117A3 (en) Serine protease
WO2001036478A3 (en) Methods and compositions relating to bactericidal/permeability increasing factor-like polypeptides and polynucleotides
WO2007073845A3 (en) Polypeptide having esterase activity and recombinant esterase and use thereof
WO2005105838A3 (en) Ion channel
EP1587928A4 (de) Menschliches saa3-nukleinsäuremolekül, -protein und verwendungsverfahren dafür
WO2002061062A3 (en) Human protein kinase n-like polypeptide and uses thereof

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties