DE602004032345D1 - Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen - Google Patents

Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen

Info

Publication number
DE602004032345D1
DE602004032345D1 DE602004032345T DE602004032345T DE602004032345D1 DE 602004032345 D1 DE602004032345 D1 DE 602004032345D1 DE 602004032345 T DE602004032345 T DE 602004032345T DE 602004032345 T DE602004032345 T DE 602004032345T DE 602004032345 D1 DE602004032345 D1 DE 602004032345D1
Authority
DE
Germany
Prior art keywords
reagents
proteins
glycosylation
bindings
forming disulfide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004032345T
Other languages
English (en)
Inventor
Benjamin Guy Davis
David Philip Gamblin
Anthony John Fairbanks
Philippe Garnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0314743A external-priority patent/GB0314743D0/en
Priority claimed from GB0328884A external-priority patent/GB0328884D0/en
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Publication of DE602004032345D1 publication Critical patent/DE602004032345D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/08—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium
    • C07H5/10—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium to sulfur
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
DE602004032345T 2003-06-24 2004-06-24 Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen Active DE602004032345D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0314743A GB0314743D0 (en) 2003-06-24 2003-06-24 Reagents and methods
GB0328884A GB0328884D0 (en) 2003-12-12 2003-12-12 Methods
PCT/GB2004/002706 WO2005000862A2 (en) 2003-06-24 2004-06-24 Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins

Publications (1)

Publication Number Publication Date
DE602004032345D1 true DE602004032345D1 (de) 2011-06-01

Family

ID=33554162

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004032345T Active DE602004032345D1 (de) 2003-06-24 2004-06-24 Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen

Country Status (13)

Country Link
US (1) US8637578B2 (de)
EP (1) EP1644390B1 (de)
JP (1) JP4787155B2 (de)
KR (1) KR20060019611A (de)
AT (1) ATE506370T1 (de)
AU (1) AU2004251105B2 (de)
BR (1) BRPI0411766A (de)
CA (1) CA2529341A1 (de)
DE (1) DE602004032345D1 (de)
EA (1) EA011299B1 (de)
IL (1) IL172729A0 (de)
NZ (1) NZ544654A (de)
WO (1) WO2005000862A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0507123D0 (en) * 2005-04-08 2005-05-11 Isis Innovation Method
CN1299603C (zh) * 2005-07-01 2007-02-14 浙江大学 糖基化谷类蛋白质－硒元素复合物制备方法
GB0602352D0 (en) * 2006-02-06 2006-03-15 Glycoform Ltd Glycoconjugation
AU2009236256B9 (en) 2008-04-14 2015-09-24 Arizona Board Of Regents On Behalf Of The University Of Arizona Small molecule inhibitors of the pleckstrin homology domain and methods for using same
EP2598638A2 (de) 2010-07-30 2013-06-05 Glycode Künstliches hefechromosom als träger des säuger-glycosylierungssignaleweges
EP2895592A1 (de) 2011-03-23 2015-07-22 Société Industrielle Limousine d'Application Biologique (SILAB) Rekombinante hefezelle zur produktion von gdp-fucose
JP6357292B2 (ja) 2012-12-14 2018-07-11 フューシス セラピューティクス、インク． Ｃｎｋｓｒ１を阻害するための方法及び組成物
WO2016077567A1 (en) * 2014-11-12 2016-05-19 Tumorend, Llc Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration
WO2016172191A1 (en) 2015-04-20 2016-10-27 Phusis Therapeutics, Inc. Compounds, compositions and methods for inhibiting cnksr1
US11931428B2 (en) * 2019-08-23 2024-03-19 Wake Forest University Health Sciences Selective hydrogen sulfide probe and uses thereof
CN112979509B (zh) * 2021-03-10 2022-04-22 江西师范大学 一种三氟甲磺酰基炔酰胺类化合物及其制备方法和用途
WO2024050809A1 (zh) * 2022-09-09 2024-03-14 四川大学 一种蛋白和/或多肽糖基化修饰的方法
EP4346356A1 (de) 2022-09-29 2024-04-03 Novaled GmbH Halbleitermaterial, verfahren zur herstellung einer schicht des halbleitermaterials, organische halbleitervorrichtung mit dem halbleitermaterial und verbindung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61205249A (ja) 1985-03-08 1986-09-11 Wako Pure Chem Ind Ltd 有機スルフイン酸塩の新規製法
EP0256486B1 (de) 1986-08-13 1990-12-05 Seitetsu Kagaku Co. Ltd. Verfahren zur Herstellung von Alkalimetallbenzolsulfinaten
EP0576592B1 (de) * 1991-03-18 2000-05-31 The Scripps Research Institute Oligosaccharide als enzymsubstrate und -inhibitoren: verfahren und zusammensetzungen
CA2072763C (en) 1992-06-29 1994-05-17 Omar Chaudhry Process for the preparation of disulfides from thiols
CA2232821A1 (en) * 1995-09-28 1997-04-03 California Institute Of Technology Metal complexes as cysteine protease inhibitors
JP2002519050A (ja) * 1998-07-02 2002-07-02 ジェネンコア インターナショナル インコーポレーテッド 炭水化物成分を有する化学的に修飾されたタンパク質
MXPA01010896A (es) 1999-04-28 2003-06-24 Genencor Int Antagonistas cataliticos especificamente dirigidos al objetivo y usos de los mismos.
US6627744B2 (en) * 1999-07-02 2003-09-30 Genencor International, Inc. Synthesis of glycodendrimer reagents

Also Published As

Publication number Publication date
CA2529341A1 (en) 2005-01-06
ATE506370T1 (de) 2011-05-15
EP1644390A2 (de) 2006-04-12
WO2005000862A2 (en) 2005-01-06
WO2005000862A3 (en) 2005-08-18
NZ544654A (en) 2009-05-31
EA011299B1 (ru) 2009-02-27
US8637578B2 (en) 2014-01-28
JP2007527376A (ja) 2007-09-27
EA200600042A1 (ru) 2006-08-25
IL172729A0 (en) 2006-04-10
BRPI0411766A (pt) 2006-08-08
KR20060019611A (ko) 2006-03-03
JP4787155B2 (ja) 2011-10-05
EP1644390B1 (de) 2011-04-20
AU2004251105B2 (en) 2010-04-01
AU2004251105A1 (en) 2005-01-06
US20070213506A1 (en) 2007-09-13

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