ATE506370T1 - Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen - Google Patents
Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinenInfo
- Publication number
- ATE506370T1 ATE506370T1 AT04743057T AT04743057T ATE506370T1 AT E506370 T1 ATE506370 T1 AT E506370T1 AT 04743057 T AT04743057 T AT 04743057T AT 04743057 T AT04743057 T AT 04743057T AT E506370 T1 ATE506370 T1 AT E506370T1
- Authority
- AT
- Austria
- Prior art keywords
- reagents
- proteins
- methods
- disulfide bonds
- glycosylation
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 230000013595 glycosylation Effects 0.000 title abstract 2
- 238000006206 glycosylation reaction Methods 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 2
- VIDTVPHHDGRGAF-UHFFFAOYSA-N selenium sulfide Chemical class [Se]=S VIDTVPHHDGRGAF-UHFFFAOYSA-N 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- GWIKYPMLNBTJHR-UHFFFAOYSA-M thiosulfonate group Chemical group S(=S)(=O)[O-] GWIKYPMLNBTJHR-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/08—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium
- C07H5/10—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium to sulfur
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0314743A GB0314743D0 (en) | 2003-06-24 | 2003-06-24 | Reagents and methods |
| GB0328884A GB0328884D0 (en) | 2003-12-12 | 2003-12-12 | Methods |
| PCT/GB2004/002706 WO2005000862A2 (en) | 2003-06-24 | 2004-06-24 | Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE506370T1 true ATE506370T1 (de) | 2011-05-15 |
Family
ID=33554162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04743057T ATE506370T1 (de) | 2003-06-24 | 2004-06-24 | Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8637578B2 (de) |
| EP (1) | EP1644390B1 (de) |
| JP (1) | JP4787155B2 (de) |
| KR (1) | KR20060019611A (de) |
| AT (1) | ATE506370T1 (de) |
| AU (1) | AU2004251105B2 (de) |
| BR (1) | BRPI0411766A (de) |
| CA (1) | CA2529341A1 (de) |
| DE (1) | DE602004032345D1 (de) |
| EA (1) | EA011299B1 (de) |
| IL (1) | IL172729A0 (de) |
| NZ (1) | NZ544654A (de) |
| WO (1) | WO2005000862A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0507123D0 (en) * | 2005-04-08 | 2005-05-11 | Isis Innovation | Method |
| CN1299603C (zh) * | 2005-07-01 | 2007-02-14 | 浙江大学 | 糖基化谷类蛋白质－硒元素复合物制备方法 |
| GB0602352D0 (en) * | 2006-02-06 | 2006-03-15 | Glycoform Ltd | Glycoconjugation |
| MX2010011258A (es) | 2008-04-14 | 2011-06-20 | Univ Texas | Inhibidores de molecula pequeña del dominio de homologia de pleckstrin y metodos para usar los mismos. |
| CA2806148A1 (en) | 2010-07-30 | 2012-02-02 | Glycode | A yeast artificial chromosome carrying the mammalian glycosylation pathway |
| WO2012127045A1 (en) | 2011-03-23 | 2012-09-27 | Glycode | A yeast recombinant cell capable of producing gdp-fucose |
| EP2931280B1 (de) | 2012-12-14 | 2018-02-14 | Phusis Therapeutics Inc. | Verfahren und zusammensetzungen zur hemmung von cnksr1 |
| EP3240411A4 (de) | 2014-11-12 | 2019-02-20 | Tumorend LLC | Zusammensetzungen, verfahren und behandlungen zur hemmung der zelladhäsion und virusbindung und penetration |
| WO2016172191A1 (en) | 2015-04-20 | 2016-10-27 | Phusis Therapeutics, Inc. | Compounds, compositions and methods for inhibiting cnksr1 |
| US11931428B2 (en) * | 2019-08-23 | 2024-03-19 | Wake Forest University Health Sciences | Selective hydrogen sulfide probe and uses thereof |
| CN112979509B (zh) * | 2021-03-10 | 2022-04-22 | 江西师范大学 | 一种三氟甲磺酰基炔酰胺类化合物及其制备方法和用途 |
| CN118451086A (zh) * | 2022-09-09 | 2024-08-06 | 四川大学 | 一种蛋白和/或多肽糖基化修饰的方法 |
| EP4346356A1 (de) | 2022-09-29 | 2024-04-03 | Novaled GmbH | Halbleitermaterial, verfahren zur herstellung einer schicht des halbleitermaterials, organische halbleitervorrichtung mit dem halbleitermaterial und verbindung |
| EP4391765A1 (de) | 2022-12-23 | 2024-06-26 | Novaled GmbH | Organische lichtemittierende diode, anzeigevorrichtung damit und verbindung |
| EP4472384B1 (de) | 2023-05-30 | 2025-11-19 | Novaled GmbH | Verbindung, organische lichtemittierende diode und anzeigevorrichtung |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61205249A (ja) | 1985-03-08 | 1986-09-11 | Wako Pure Chem Ind Ltd | 有機スルフイン酸塩の新規製法 |
| DE3766567D1 (de) | 1986-08-13 | 1991-01-17 | Seitetsu Kagaku Co Ltd | Verfahren zur herstellung von alkalimetallbenzolsulfinaten. |
| ATE193551T1 (de) * | 1991-03-18 | 2000-06-15 | Scripps Research Inst | Oligosaccharide als enzymsubstrate und - inhibitoren: verfahren und zusammensetzungen |
| CA2072763C (en) | 1992-06-29 | 1994-05-17 | Omar Chaudhry | Process for the preparation of disulfides from thiols |
| AU728515B2 (en) * | 1995-09-28 | 2001-01-11 | Redox Pharmaceutical Corporation | Metal complexes as cysteine protease inhibitors |
| DE69939538D1 (de) * | 1998-07-02 | 2008-10-23 | Univ Toronto | Mit einer kohlenhydratgruppe chemisch modifizierte proteine |
| AU781451B2 (en) * | 1999-04-28 | 2005-05-26 | Genencor International, Inc. | Specifically targeted catalytic antagonists and uses thereof |
| US6627744B2 (en) | 1999-07-02 | 2003-09-30 | Genencor International, Inc. | Synthesis of glycodendrimer reagents |
-
2004
- 2004-06-24 EP EP04743057A patent/EP1644390B1/de not_active Expired - Lifetime
- 2004-06-24 AU AU2004251105A patent/AU2004251105B2/en not_active Expired - Fee Related
- 2004-06-24 US US10/562,599 patent/US8637578B2/en active Active
- 2004-06-24 AT AT04743057T patent/ATE506370T1/de not_active IP Right Cessation
- 2004-06-24 NZ NZ544654A patent/NZ544654A/en not_active IP Right Cessation
- 2004-06-24 EA EA200600042A patent/EA011299B1/ru not_active IP Right Cessation
- 2004-06-24 JP JP2006516469A patent/JP4787155B2/ja not_active Expired - Fee Related
- 2004-06-24 KR KR1020057024634A patent/KR20060019611A/ko not_active Ceased
- 2004-06-24 WO PCT/GB2004/002706 patent/WO2005000862A2/en not_active Ceased
- 2004-06-24 BR BRPI0411766-2A patent/BRPI0411766A/pt not_active IP Right Cessation
- 2004-06-24 CA CA002529341A patent/CA2529341A1/en not_active Abandoned
- 2004-06-24 DE DE602004032345T patent/DE602004032345D1/de not_active Expired - Lifetime
-
2005
- 2005-12-21 IL IL172729A patent/IL172729A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005000862A3 (en) | 2005-08-18 |
| EA011299B1 (ru) | 2009-02-27 |
| DE602004032345D1 (de) | 2011-06-01 |
| KR20060019611A (ko) | 2006-03-03 |
| AU2004251105A1 (en) | 2005-01-06 |
| EP1644390B1 (de) | 2011-04-20 |
| NZ544654A (en) | 2009-05-31 |
| US8637578B2 (en) | 2014-01-28 |
| US20070213506A1 (en) | 2007-09-13 |
| BRPI0411766A (pt) | 2006-08-08 |
| WO2005000862A2 (en) | 2005-01-06 |
| AU2004251105B2 (en) | 2010-04-01 |
| EP1644390A2 (de) | 2006-04-12 |
| IL172729A0 (en) | 2006-04-10 |
| JP2007527376A (ja) | 2007-09-27 |
| JP4787155B2 (ja) | 2011-10-05 |
| EA200600042A1 (ru) | 2006-08-25 |
| CA2529341A1 (en) | 2005-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |