DE602004032042D1 - Bibliotheken rekombinanter chimärischer proteine - Google Patents

Bibliotheken rekombinanter chimärischer proteine

Info

Publication number
DE602004032042D1
DE602004032042D1 DE602004032042T DE602004032042T DE602004032042D1 DE 602004032042 D1 DE602004032042 D1 DE 602004032042D1 DE 602004032042 T DE602004032042 T DE 602004032042T DE 602004032042 T DE602004032042 T DE 602004032042T DE 602004032042 D1 DE602004032042 D1 DE 602004032042D1
Authority
DE
Germany
Prior art keywords
chimeric proteins
recombinant chimeric
libraries
amino acid
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004032042T
Other languages
English (en)
Inventor
Gil Sharon
Abraham Laban
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PROTEREC Ltd
Original Assignee
PROTEREC Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PROTEREC Ltd filed Critical PROTEREC Ltd
Publication of DE602004032042D1 publication Critical patent/DE602004032042D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE602004032042T 2003-08-27 2004-08-26 Bibliotheken rekombinanter chimärischer proteine Active DE602004032042D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49792403P 2003-08-27 2003-08-27
US10/926,542 US20050053989A1 (en) 2003-08-27 2004-08-26 Libraries of recombinant chimeric proteins
PCT/US2004/027793 WO2005021719A2 (en) 2003-08-27 2004-08-26 Libraries of recombinant chimeric proteins

Publications (1)

Publication Number Publication Date
DE602004032042D1 true DE602004032042D1 (de) 2011-05-12

Family

ID=34228622

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004032042T Active DE602004032042D1 (de) 2003-08-27 2004-08-26 Bibliotheken rekombinanter chimärischer proteine

Country Status (6)

Country Link
US (1) US20050053989A1 (de)
EP (2) EP1670932B1 (de)
AT (1) ATE503834T1 (de)
DE (1) DE602004032042D1 (de)
IL (1) IL173954A0 (de)
WO (1) WO2005021719A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100069264A1 (en) * 2003-08-27 2010-03-18 Gil Sharon Libraries of recombinant chimeric proteins
AU2013201171B2 (en) * 2006-02-13 2016-01-21 Monsanto Technology Llc Plant chimeric binding polypeptides for universal molecular recognition
AU2015203464B2 (en) * 2006-02-13 2017-08-10 Monsanto Technology Llc Plant chimeric binding polypeptides for universal molecular recognition
AR059448A1 (es) 2006-02-13 2008-04-09 Divergence Inc Polipeptidos quimericos vegetales de union para el reconocimiento molecular universal
EP2470653A1 (de) * 2009-08-26 2012-07-04 Research Development Foundation Verfahren zur erstellung von antikörperbibliotheken
BR112015026716A2 (pt) * 2013-04-23 2017-09-05 The Univ Court Of The Univ Of Aberdeen Molécula de ligação de antígeno específica do icosl; proteína de fusão; ácido nucleico que codifica uma molécula de ligação de antígeno específica do icosl; construto de ácido nucleico; célula hospedeira; processo para produção de uma molécula de ligação de antígeno específica do icosl; composição farmacêutica de uma molécula de ligação de antígeno específica do icosl; uso de uma molécula de ligação de antígeno específica do icosl; método de tratamento de uma doença em um paciente em necessidade de tratamento; método de ensaio de um analito alvo em uma amostra; método de formação de imagem de um local da doença em um indivíduo; e método de diagnóstico de uma doença ou condição médica em um indivíduo
WO2016064742A1 (en) * 2014-10-21 2016-04-28 The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las Vegas Methods and compositions for screening molecular function comprising chimeric minimotifs

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US6107059A (en) * 1992-04-29 2000-08-22 Affymax Technologies N.V. Peptide library and screening method
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6335160B1 (en) * 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6165793A (en) * 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6489145B1 (en) 1996-07-09 2002-12-03 Diversa Corporation Method of DNA shuffling
US6537776B1 (en) * 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
GB9701425D0 (en) * 1997-01-24 1997-03-12 Bioinvent Int Ab A method for in vitro molecular evolution of protein function
IL120339A0 (en) * 1997-02-27 1997-06-10 Gesher Israel Advanced Biotecs Improved DNA assembly method
AU5347999A (en) * 1998-08-12 2000-03-06 Maxygen, Inc. Dna shuffling of monooxygenase genes for production of industrial chemicals
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
EP1144616B2 (de) * 1999-01-19 2009-01-14 Unilever Plc Verfahren zur herstellung von antikörperfragmenten
GB0008419D0 (en) * 2000-04-05 2000-05-24 Bioinvent Int Ab A method for invitro molecular evolution of antibody function
WO2003044198A1 (fr) 2001-11-22 2003-05-30 Keio University Banque d'anticorps artificiels dotee d'un super repertoire
WO2006047669A2 (en) * 2004-10-27 2006-05-04 Monsanto Technology Llc Non-random method of gene shuffling

Also Published As

Publication number Publication date
EP2261332A3 (de) 2012-05-09
EP2261332A2 (de) 2010-12-15
EP1670932A4 (de) 2008-05-28
EP1670932A2 (de) 2006-06-21
WO2005021719A3 (en) 2006-05-04
WO2005021719A2 (en) 2005-03-10
US20050053989A1 (en) 2005-03-10
IL173954A0 (en) 2006-07-05
ATE503834T1 (de) 2011-04-15
EP1670932B1 (de) 2011-03-30

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