ATE477272T1 - Verwendung von stefin a als gerüstprotein - Google Patents
Verwendung von stefin a als gerüstproteinInfo
- Publication number
- ATE477272T1 ATE477272T1 AT06744166T AT06744166T ATE477272T1 AT E477272 T1 ATE477272 T1 AT E477272T1 AT 06744166 T AT06744166 T AT 06744166T AT 06744166 T AT06744166 T AT 06744166T AT E477272 T1 ATE477272 T1 AT E477272T1
- Authority
- AT
- Austria
- Prior art keywords
- stefin
- scaffold
- mutations
- relates
- leu73
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000035772 mutation Effects 0.000 abstract 5
- 101710167800 Capsid assembly scaffolding protein Proteins 0.000 abstract 4
- 101710130420 Probable capsid assembly scaffolding protein Proteins 0.000 abstract 4
- 101710204410 Scaffold protein Proteins 0.000 abstract 4
- 102220591835 Charged multivesicular body protein 3_V48D_mutation Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102220237123 rs74315443 Human genes 0.000 abstract 3
- 102000012193 Cystatin A Human genes 0.000 abstract 2
- 108010061641 Cystatin A Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 101000921786 Homo sapiens Cystatin-A Proteins 0.000 abstract 1
- 102000023732 binding proteins Human genes 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 102000045247 human CSTA Human genes 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108010091748 peptide A Proteins 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0511873A GB0511873D0 (en) | 2005-06-10 | 2005-06-10 | Scaffold |
| GB0608836A GB0608836D0 (en) | 2006-05-04 | 2006-05-04 | Scaffold |
| PCT/GB2006/002115 WO2006131749A2 (en) | 2005-06-10 | 2006-06-08 | Scaffold |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE477272T1 true ATE477272T1 (de) | 2010-08-15 |
Family
ID=37314237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06744166T ATE477272T1 (de) | 2005-06-10 | 2006-06-08 | Verwendung von stefin a als gerüstprotein |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8063019B2 (enExample) |
| EP (1) | EP1904529B1 (enExample) |
| JP (1) | JP4989638B2 (enExample) |
| AT (1) | ATE477272T1 (enExample) |
| AU (1) | AU2006256530B2 (enExample) |
| CA (1) | CA2610976C (enExample) |
| DE (1) | DE602006016133D1 (enExample) |
| DK (1) | DK1904529T3 (enExample) |
| WO (1) | WO2006131749A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE477272T1 (de) * | 2005-06-10 | 2010-08-15 | Medical Res Council | Verwendung von stefin a als gerüstprotein |
| GB0807065D0 (en) * | 2008-04-18 | 2008-05-21 | Univ Leeds | Novel scaffolds |
| GB201302597D0 (en) | 2013-02-14 | 2013-04-03 | Univ Leeds | Novel Synthetic Proteins |
| CN106573961B (zh) | 2014-06-20 | 2022-01-04 | 豪夫迈·罗氏有限公司 | 基于chagasin的支架组合物、方法和应用 |
| EP3405579A1 (en) | 2016-01-22 | 2018-11-28 | Modernatx, Inc. | Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof |
| FI4112741T3 (fi) | 2017-01-04 | 2025-05-15 | Mgi Tech Co Ltd | Vaiheittainen sekvensointi ei-leimatuilla, reversiibeleillä terminaattoreilla tai luonnollisilla nukleotideilla |
| WO2018211126A1 (en) | 2017-05-19 | 2018-11-22 | Philip Morris Products S.A. | Diagnostic test for distinguishing the smoking status of a subject |
| GB201710973D0 (en) * | 2017-07-07 | 2017-08-23 | Avacta Life Sciences Ltd | Scaffold proteins |
| AU2020367510B2 (en) * | 2019-10-16 | 2025-06-26 | Lg Chem, Ltd. | Neonatal Fc receptor binding AFFIMERs |
| GB202101299D0 (en) | 2020-06-09 | 2021-03-17 | Avacta Life Sciences Ltd | Diagnostic polypetides and methods |
| CN116783302A (zh) | 2020-10-09 | 2023-09-19 | 深圳华大基因科技有限公司 | 用于基于生物发光的测序的方法和组合物 |
| WO2023153876A1 (ko) * | 2022-02-10 | 2023-08-17 | 주식회사 아피셀테라퓨틱스 | Cd40l에 특이적으로 결합하는 스테핀 a 단백질 변이체 및 이의 용도 |
| WO2023182945A2 (en) * | 2022-03-24 | 2023-09-28 | Agency For Science, Technology And Research | Engineering peptides using peptide epitope linker evolution |
| US20260022343A1 (en) * | 2022-12-29 | 2026-01-22 | Affyxell Therapeutics Co., Ltd. | Genetically modified cells comprising a nucleic acid encoding a cd40l binding agent and uses thereof |
| GB202403780D0 (en) | 2024-03-15 | 2024-05-01 | Avacta Life Sciences Ltd | Polypeptides and methods for detecting and quantifying small molecules |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996016173A2 (en) * | 1994-11-21 | 1996-05-30 | The University Of Leeds | Modified proteinase inhibitors |
| DE69902924T2 (de) * | 1998-07-20 | 2003-05-28 | Inoxell A/S, Horsholm | Neue methoden zum auffinden von liganden- und ziel-biomolekülen |
| CA2544820C (en) * | 2003-11-06 | 2014-02-18 | Genencor International, Inc. | Bacterial expression of protease inhibitors and variants thereof |
| ATE477272T1 (de) * | 2005-06-10 | 2010-08-15 | Medical Res Council | Verwendung von stefin a als gerüstprotein |
-
2006
- 2006-06-08 AT AT06744166T patent/ATE477272T1/de active
- 2006-06-08 AU AU2006256530A patent/AU2006256530B2/en not_active Ceased
- 2006-06-08 DE DE602006016133T patent/DE602006016133D1/de not_active Expired - Lifetime
- 2006-06-08 CA CA2610976A patent/CA2610976C/en not_active Expired - Lifetime
- 2006-06-08 US US11/917,057 patent/US8063019B2/en active Active
- 2006-06-08 DK DK06744166.7T patent/DK1904529T3/da active
- 2006-06-08 JP JP2008515292A patent/JP4989638B2/ja not_active Expired - Fee Related
- 2006-06-08 EP EP06744166A patent/EP1904529B1/en not_active Expired - Lifetime
- 2006-06-08 WO PCT/GB2006/002115 patent/WO2006131749A2/en not_active Ceased
-
2011
- 2011-09-23 US US13/243,318 patent/US8481491B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1904529B1 (en) | 2010-08-11 |
| EP1904529A2 (en) | 2008-04-02 |
| AU2006256530B2 (en) | 2012-12-20 |
| US20080207509A1 (en) | 2008-08-28 |
| WO2006131749A2 (en) | 2006-12-14 |
| US8063019B2 (en) | 2011-11-22 |
| DE602006016133D1 (de) | 2010-09-23 |
| US20120190819A1 (en) | 2012-07-26 |
| CA2610976C (en) | 2020-11-24 |
| AU2006256530A1 (en) | 2006-12-14 |
| CA2610976A1 (en) | 2006-12-14 |
| JP2008541776A (ja) | 2008-11-27 |
| US8481491B2 (en) | 2013-07-09 |
| WO2006131749A3 (en) | 2007-05-18 |
| JP4989638B2 (ja) | 2012-08-01 |
| DK1904529T3 (da) | 2010-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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