DK1530637T3 - Carlsberg-subtilisin-proteiner med nedsat immunogenitet - Google Patents
Carlsberg-subtilisin-proteiner med nedsat immunogenitetInfo
- Publication number
- DK1530637T3 DK1530637T3 DK03711261.2T DK03711261T DK1530637T3 DK 1530637 T3 DK1530637 T3 DK 1530637T3 DK 03711261 T DK03711261 T DK 03711261T DK 1530637 T3 DK1530637 T3 DK 1530637T3
- Authority
- DK
- Denmark
- Prior art keywords
- present
- reduced immunogenicity
- proteins
- provides
- carlsberg subtilisin
- Prior art date
Links
- 108010056079 Subtilisins Proteins 0.000 title abstract 4
- 102000005158 Subtilisins Human genes 0.000 title abstract 4
- 230000005847 immunogenicity Effects 0.000 title abstract 2
- 230000009851 immunogenic response Effects 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61Q11/02—Preparations for deodorising, bleaching or disinfecting dentures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/22—Gas releasing
- A61K2800/222—Effervescent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cosmetics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36005702P | 2002-02-26 | 2002-02-26 | |
US38477702P | 2002-05-30 | 2002-05-30 | |
PCT/US2003/005861 WO2003072746A2 (en) | 2002-02-26 | 2003-02-26 | Subtilisin carlsberg proteins with reduced immunogenicity |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1530637T3 true DK1530637T3 (da) | 2010-05-31 |
Family
ID=27767590
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03711261.2T DK1530637T3 (da) | 2002-02-26 | 2003-02-26 | Carlsberg-subtilisin-proteiner med nedsat immunogenitet |
Country Status (10)
Country | Link |
---|---|
US (2) | US20050239043A1 (da) |
EP (1) | EP1530637B1 (da) |
JP (1) | JP4597528B2 (da) |
AT (1) | ATE457352T1 (da) |
AU (1) | AU2003213580A1 (da) |
CA (1) | CA2476890C (da) |
DE (1) | DE60331224D1 (da) |
DK (1) | DK1530637T3 (da) |
MX (1) | MXPA04008144A (da) |
WO (1) | WO2003072746A2 (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7820186B2 (en) * | 2001-12-21 | 2010-10-26 | Galderma Research & Development | Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt |
US20050164308A1 (en) * | 2003-12-18 | 2005-07-28 | Fiona Harding | Beta-lactamase CD4+ T-cell epitopes |
WO2005119259A2 (en) * | 2004-04-26 | 2005-12-15 | Genencor International, Inc. | Population based prediction methods for immune response determinations and methods for verifying immunological response data |
US7378382B2 (en) * | 2004-05-05 | 2008-05-27 | The Clorox Company | Rheologically stabilized silicone dispersions comprising a polydimethylsiloxane mixture |
WO2007067473A2 (en) * | 2005-12-06 | 2007-06-14 | Genencor International, Inc. | Perhydrolase epitopes |
FR2910320B1 (fr) * | 2006-12-21 | 2009-02-13 | Galderma Res & Dev S N C Snc | Emulsion comprenant au moins un retinoide et du peroxyde de benzole |
FR2910321B1 (fr) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
EP2090646A1 (en) * | 2008-01-22 | 2009-08-19 | Thermphos Trading GmbH | Surface treatment composition containing phosphonic acid compounds |
EP3173479A1 (en) | 2008-06-06 | 2017-05-31 | Danisco US Inc. | Compositions and methods comprising variant microbial proteases |
BRPI0921041A2 (pt) | 2008-11-11 | 2019-09-24 | Danisco Us Inc | composições e métodos que compreendem uma variante de subtilisina |
US7829513B2 (en) * | 2009-03-12 | 2010-11-09 | Greenology Products, Inc. | Organic cleaning composition |
GB0915572D0 (en) | 2009-09-07 | 2009-10-07 | Reckitt Benckiser Nv | Detergent composition |
CN102762222B (zh) * | 2009-12-09 | 2015-11-25 | 丹尼斯科美国公司 | 包含蛋白酶变体的组合物和方法 |
MX349991B (es) | 2011-12-21 | 2017-08-22 | Colgate Palmolive Co | Composiciones de cuidado oral. |
IL285403B2 (en) | 2014-01-27 | 2023-10-01 | Molecular Templates Inc | Polypeptides that remove an epitope for MHC group I |
JP6749745B2 (ja) * | 2014-02-27 | 2020-09-02 | キッコーマン株式会社 | アマドリアーゼ含有組成物の安定化方法、熱安定性が向上したアマドリアーゼ含有組成物及びこれを用いた糖化ヘモグロビン測定用組成物 |
KR102647100B1 (ko) * | 2015-05-30 | 2024-03-13 | 몰레큘러 템플레이츠, 인코퍼레이션. | 탈면역된 시가 독소 a 서브유닛 스캐폴드 및 이를 포함하는 세포-표적화 분자 |
JP7075134B2 (ja) | 2016-12-07 | 2022-05-25 | モレキュラー テンプレーツ,インク. | 部位特異的コンジュゲーションのための志賀毒素aサブユニットエフェクターポリペプチド、志賀毒素エフェクター足場、及び細胞標的化分子 |
US20200024312A1 (en) | 2017-01-25 | 2020-01-23 | Molecular Templates, Inc. | Cell-targeting molecules comprising de-immunized, shiga toxin a subunit effectors and cd8+ t-cell epitopes |
CN111205938B (zh) * | 2020-01-15 | 2023-11-24 | 上海太阳生物技术有限公司 | 低泡型冲洗液及其应用 |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3755560A (en) * | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
JPS5638032B2 (da) * | 1972-08-31 | 1981-09-03 | ||
JPS51125468A (en) * | 1975-03-27 | 1976-11-01 | Sanyo Chem Ind Ltd | Method of preparing resins of high water absorbency |
US4152416A (en) * | 1976-09-17 | 1979-05-01 | Marra Dorothea C | Aerosol antiperspirant compositions delivering astringent salt with low mistiness and dustiness |
NL190101C (nl) * | 1978-11-13 | 1993-11-01 | Givaudan & Cie Sa | Dibenzoylmethaanverbinding en tegen licht beschermend preparaat. |
US4261868A (en) * | 1979-08-08 | 1981-04-14 | Lever Brothers Company | Stabilized enzymatic liquid detergent composition containing a polyalkanolamine and a boron compound |
US4404128A (en) * | 1981-05-29 | 1983-09-13 | The Procter & Gamble Company | Enzyme detergent composition |
US4421769A (en) * | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
JPS58144105A (ja) * | 1982-02-12 | 1983-08-27 | Kurabo Ind Ltd | スケ−ル除去獣毛繊維の製法 |
US4760025A (en) * | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
US5204015A (en) * | 1984-05-29 | 1993-04-20 | Genencor International, Inc. | Subtilisin mutants |
US5264366A (en) * | 1984-05-29 | 1993-11-23 | Genencor, Inc. | Protease deficient bacillus |
US5185258A (en) * | 1984-05-29 | 1993-02-09 | Genencor International, Inc. | Subtilisin mutants |
US4663157A (en) * | 1985-02-28 | 1987-05-05 | The Proctor & Gamble Company | Sunscreen compositions |
US4937370A (en) * | 1987-06-02 | 1990-06-26 | The Procter & Gamble Company | Novel chromophores, sunscreen compositions and methods for preventing sunburn |
US4999186A (en) * | 1986-06-27 | 1991-03-12 | The Procter & Gamble Company | Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn |
US5028414A (en) * | 1987-07-17 | 1991-07-02 | The Procter & Gamble Company | Anaerobe-selective antibacterial compositions and methods |
US5028415A (en) * | 1987-08-17 | 1991-07-02 | The Procter & Gamble Company | Oral compositions and method for reducing dental calculus |
DE3856302T2 (de) * | 1987-10-22 | 1999-09-09 | Procter & Gamble | Chelatbildner enthaltende Lichtschutzmittel |
US5785973A (en) * | 1988-02-01 | 1998-07-28 | Praxis Biologics, Inc. | Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines |
US5055305A (en) * | 1988-12-02 | 1991-10-08 | Richardson-Vicks, Inc. | Cleansing compositions |
EP0628570A1 (en) * | 1989-02-17 | 1994-12-14 | Chiron Mimotopes Pty. Ltd. | Method for the use and synthesis of peptides |
US5087372A (en) * | 1989-03-24 | 1992-02-11 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for removing heavy metal ions from contaminated water and a porous membrane usable therefor |
US5011681A (en) * | 1989-10-11 | 1991-04-30 | Richardson-Vicks, Inc. | Facial cleansing compositions |
US5194639A (en) * | 1990-09-28 | 1993-03-16 | The Procter & Gamble Company | Preparation of polyhydroxy fatty acid amides in the presence of solvents |
US5096700A (en) * | 1990-09-28 | 1992-03-17 | The Procter & Gamble Company | Halogenated aminohexanoates and aminobutyrates antimicrobial agents |
US5073371A (en) * | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
US5073372A (en) * | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
EP0662136B1 (en) * | 1992-09-24 | 2002-05-08 | Genencor International, Inc. | Cleaning compositions containing novel alkaline proteases |
US5827508A (en) * | 1996-09-27 | 1998-10-27 | The Procter & Gamble Company | Stable photoprotective compositions |
US6416756B1 (en) * | 1997-01-10 | 2002-07-09 | Novozymes A/S | Modified protease having 5 to 13 covalently coupled polymeric molecules for skin care |
US6495136B1 (en) * | 1998-03-26 | 2002-12-17 | The Procter & Gamble Company | Proteases having modified amino acid sequences conjugated to addition moieties |
US6642011B2 (en) * | 1998-04-15 | 2003-11-04 | Genencor International, Inc. | Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins |
US6838269B1 (en) * | 1998-04-15 | 2005-01-04 | Genencor International, Inc. | Proteins producing an altered immunogenic response and methods of making and using the same |
US6835550B1 (en) * | 1998-04-15 | 2004-12-28 | Genencor International, Inc. | Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins |
US5935556A (en) * | 1998-07-30 | 1999-08-10 | The Procter & Gamble Company | Sunscreen compositions |
AU6078899A (en) * | 1998-10-13 | 2000-05-01 | Novozymes A/S | A modified polypeptide with reduced immune response |
US5968485A (en) * | 1998-10-16 | 1999-10-19 | The Procter & Gamble Company | UV protection compositions |
US5972316A (en) * | 1998-10-16 | 1999-10-26 | The Procter & Gamble Company | UV protection compositions |
WO2002010183A1 (en) * | 2000-07-31 | 2002-02-07 | Menzel, Rolf | Compositions and methods for directed gene assembly |
ES2309167T3 (es) * | 2001-02-19 | 2008-12-16 | Merck Patent Gmbh | Metodo para identificar epitotes de celulas t y metodo para preparar moleculas con inmunogenicidad reducida. |
-
2003
- 2003-02-26 DE DE60331224T patent/DE60331224D1/de not_active Expired - Lifetime
- 2003-02-26 WO PCT/US2003/005861 patent/WO2003072746A2/en active Application Filing
- 2003-02-26 US US10/503,706 patent/US20050239043A1/en not_active Abandoned
- 2003-02-26 AT AT03711261T patent/ATE457352T1/de not_active IP Right Cessation
- 2003-02-26 EP EP03711261A patent/EP1530637B1/en not_active Revoked
- 2003-02-26 MX MXPA04008144A patent/MXPA04008144A/es active IP Right Grant
- 2003-02-26 DK DK03711261.2T patent/DK1530637T3/da active
- 2003-02-26 AU AU2003213580A patent/AU2003213580A1/en not_active Abandoned
- 2003-02-26 JP JP2003571434A patent/JP4597528B2/ja not_active Expired - Fee Related
- 2003-02-26 CA CA2476890A patent/CA2476890C/en not_active Expired - Lifetime
-
2008
- 2008-12-17 US US12/337,358 patent/US20090162917A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20090162917A1 (en) | 2009-06-25 |
JP2006513691A (ja) | 2006-04-27 |
WO2003072746A3 (en) | 2005-03-24 |
EP1530637A2 (en) | 2005-05-18 |
ATE457352T1 (de) | 2010-02-15 |
WO2003072746A2 (en) | 2003-09-04 |
CA2476890C (en) | 2013-07-16 |
AU2003213580A1 (en) | 2003-09-09 |
EP1530637A4 (en) | 2007-03-21 |
US20050239043A1 (en) | 2005-10-27 |
CA2476890A1 (en) | 2003-09-04 |
JP4597528B2 (ja) | 2010-12-15 |
DE60331224D1 (de) | 2010-03-25 |
AU2003213580A8 (en) | 2003-09-09 |
MXPA04008144A (es) | 2004-11-26 |
EP1530637B1 (en) | 2010-02-10 |
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