JP2008505177A5 - - Google Patents
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- Publication number
- JP2008505177A5 JP2008505177A5 JP2007520365A JP2007520365A JP2008505177A5 JP 2008505177 A5 JP2008505177 A5 JP 2008505177A5 JP 2007520365 A JP2007520365 A JP 2007520365A JP 2007520365 A JP2007520365 A JP 2007520365A JP 2008505177 A5 JP2008505177 A5 JP 2008505177A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- omega
- fatty acid
- acid
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000203 mixture Substances 0.000 claims 63
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 23
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 23
- 235000020665 omega-6 fatty acid Nutrition 0.000 claims 23
- 229940033080 omega-6 fatty acid Drugs 0.000 claims 23
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 19
- 239000004094 surface-active agent Substances 0.000 claims 15
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 12
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 10
- 238000002360 preparation method Methods 0.000 claims 10
- 235000014113 dietary fatty acids Nutrition 0.000 claims 8
- 229930195729 fatty acid Natural products 0.000 claims 8
- 239000000194 fatty acid Substances 0.000 claims 8
- 150000004665 fatty acids Chemical class 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 claims 6
- 235000021298 Dihomo-γ-linolenic acid Nutrition 0.000 claims 6
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 6
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 claims 6
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 6
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 6
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 6
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 6
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 6
- VZCCETWTMQHEPK-UHFFFAOYSA-N gamma-Linolensaeure Natural products CCCCCC=CCC=CCC=CCCCCC(O)=O VZCCETWTMQHEPK-UHFFFAOYSA-N 0.000 claims 6
- 235000020664 gamma-linolenic acid Nutrition 0.000 claims 6
- VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 claims 6
- 229960002733 gamolenic acid Drugs 0.000 claims 6
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims 5
- 229960004488 linolenic acid Drugs 0.000 claims 5
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims 4
- HOVAGTYPODGVJG-UVSYOFPXSA-N (3s,5r)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol Chemical class COC1OC(CO)[C@@H](O)C(O)[C@H]1O HOVAGTYPODGVJG-UVSYOFPXSA-N 0.000 claims 3
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical group FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 claims 3
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 3
- 206010013774 Dry eye Diseases 0.000 claims 3
- 206010061218 Inflammation Diseases 0.000 claims 3
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims 3
- 230000004054 inflammatory process Effects 0.000 claims 3
- 229920001983 poloxamer Polymers 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 3
- 238000011200 topical administration Methods 0.000 claims 3
- 235000021342 arachidonic acid Nutrition 0.000 claims 2
- 229940114079 arachidonic acid Drugs 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 235000020778 linoleic acid Nutrition 0.000 claims 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 claims 2
- -1 omega-3 fatty acid compound Chemical class 0.000 claims 2
- 239000006014 omega-3 oil Substances 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 239000007972 injectable composition Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58451404P | 2004-07-01 | 2004-07-01 | |
| PCT/US2005/023113 WO2006007510A1 (en) | 2004-07-01 | 2005-06-30 | Compositions and methods for treating eye disorders and conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008505177A JP2008505177A (ja) | 2008-02-21 |
| JP2008505177A5 true JP2008505177A5 (enExample) | 2008-12-04 |
Family
ID=35784207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007520365A Pending JP2008505177A (ja) | 2004-07-01 | 2005-06-30 | 目の障害および状態を治療するための組成物および方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20060009522A1 (enExample) |
| EP (1) | EP1781278B2 (enExample) |
| JP (1) | JP2008505177A (enExample) |
| KR (1) | KR20070040381A (enExample) |
| CN (1) | CN101043884A (enExample) |
| AU (1) | AU2005262392A1 (enExample) |
| BR (1) | BRPI0512864B8 (enExample) |
| CA (1) | CA2572344A1 (enExample) |
| IL (1) | IL180342A0 (enExample) |
| MX (1) | MX2007000208A (enExample) |
| NO (1) | NO20070561L (enExample) |
| NZ (1) | NZ552481A (enExample) |
| RU (1) | RU2007103835A (enExample) |
| WO (1) | WO2006007510A1 (enExample) |
| ZA (1) | ZA200700918B (enExample) |
Families Citing this family (63)
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| US20060251685A1 (en) * | 2003-03-18 | 2006-11-09 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with Omega-3 fatty acids for alleviating dry eye |
| AU2005296212A1 (en) * | 2004-10-19 | 2006-04-27 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Topical treatment with NGF and DHA in damaged corneas |
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| US8343753B2 (en) | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
| US20100010088A1 (en) * | 2007-11-01 | 2010-01-14 | Wake Forest University School Of Medicine | Compositions and Methods for Prevention and Treatment of Mammalian Diseases |
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| JP6642935B2 (ja) | 2015-09-30 | 2020-02-12 | ノバリック ゲーエムベーハー | 眼投与用の半フッ素化化合物 |
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| CN106963728A (zh) * | 2016-01-13 | 2017-07-21 | 汤欣 | 一种二十二碳六烯酸结膜下注射液的制备方法及其应用 |
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| JP7032404B2 (ja) | 2016-12-23 | 2022-03-08 | ノバリック ゲーエムベーハー | ドライアイ疾患の治療のための眼科用組成物 |
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| CN110650734B (zh) | 2017-05-12 | 2024-11-15 | 诺瓦利克有限责任公司 | 治疗与隐形眼镜有关病症的包含半氟化烷烃的药物组合物 |
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-
2005
- 2005-06-30 CN CNA2005800287299A patent/CN101043884A/zh active Pending
- 2005-06-30 KR KR1020077002456A patent/KR20070040381A/ko not_active Withdrawn
- 2005-06-30 BR BRPI0512864A patent/BRPI0512864B8/pt not_active IP Right Cessation
- 2005-06-30 AU AU2005262392A patent/AU2005262392A1/en not_active Abandoned
- 2005-06-30 EP EP05767809.6A patent/EP1781278B2/en not_active Expired - Lifetime
- 2005-06-30 NZ NZ552481A patent/NZ552481A/en unknown
- 2005-06-30 MX MX2007000208A patent/MX2007000208A/es not_active Application Discontinuation
- 2005-06-30 WO PCT/US2005/023113 patent/WO2006007510A1/en not_active Ceased
- 2005-06-30 JP JP2007520365A patent/JP2008505177A/ja active Pending
- 2005-06-30 CA CA002572344A patent/CA2572344A1/en not_active Abandoned
- 2005-06-30 RU RU2007103835/15A patent/RU2007103835A/ru not_active Application Discontinuation
- 2005-06-30 US US11/171,815 patent/US20060009522A1/en not_active Abandoned
-
2006
- 2006-12-26 IL IL180342A patent/IL180342A0/en unknown
-
2007
- 2007-01-30 NO NO20070561A patent/NO20070561L/no not_active Application Discontinuation
- 2007-01-31 ZA ZA200700918A patent/ZA200700918B/xx unknown
- 2007-10-17 US US11/873,478 patent/US20080153909A1/en not_active Abandoned
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