CA2572344A1 - Compositions and methods for treating eye disorders and conditions - Google Patents
Compositions and methods for treating eye disorders and conditions Download PDFInfo
- Publication number
- CA2572344A1 CA2572344A1 CA002572344A CA2572344A CA2572344A1 CA 2572344 A1 CA2572344 A1 CA 2572344A1 CA 002572344 A CA002572344 A CA 002572344A CA 2572344 A CA2572344 A CA 2572344A CA 2572344 A1 CA2572344 A1 CA 2572344A1
- Authority
- CA
- Canada
- Prior art keywords
- omega
- composition
- fatty acid
- acid
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58451404P | 2004-07-01 | 2004-07-01 | |
| US60/584,514 | 2004-07-01 | ||
| PCT/US2005/023113 WO2006007510A1 (en) | 2004-07-01 | 2005-06-30 | Compositions and methods for treating eye disorders and conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2572344A1 true CA2572344A1 (en) | 2006-01-19 |
Family
ID=35784207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002572344A Abandoned CA2572344A1 (en) | 2004-07-01 | 2005-06-30 | Compositions and methods for treating eye disorders and conditions |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20060009522A1 (enExample) |
| EP (1) | EP1781278B2 (enExample) |
| JP (1) | JP2008505177A (enExample) |
| KR (1) | KR20070040381A (enExample) |
| CN (1) | CN101043884A (enExample) |
| AU (1) | AU2005262392A1 (enExample) |
| BR (1) | BRPI0512864B8 (enExample) |
| CA (1) | CA2572344A1 (enExample) |
| IL (1) | IL180342A0 (enExample) |
| MX (1) | MX2007000208A (enExample) |
| NO (1) | NO20070561L (enExample) |
| NZ (1) | NZ552481A (enExample) |
| RU (1) | RU2007103835A (enExample) |
| WO (1) | WO2006007510A1 (enExample) |
| ZA (1) | ZA200700918B (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060251685A1 (en) * | 2003-03-18 | 2006-11-09 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with Omega-3 fatty acids for alleviating dry eye |
| US20070218105A1 (en) * | 2004-10-19 | 2007-09-20 | Salomon Esquenazi | Topical Treatment with NGF and DHA in Damaged Corneas |
| US20070293410A1 (en) * | 2006-06-15 | 2007-12-20 | Surowiak Richard J | Contact lens and method for preventing contact lens intolerance |
| US8343753B2 (en) | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
| US20100010088A1 (en) * | 2007-11-01 | 2010-01-14 | Wake Forest University School Of Medicine | Compositions and Methods for Prevention and Treatment of Mammalian Diseases |
| IT1393419B1 (it) * | 2009-03-19 | 2012-04-20 | Medivis S R L | Composizioni oftalmiche a base di acidi grassi polinsaturi omega-3 e omega-6. |
| GB0907413D0 (en) | 2009-04-29 | 2009-06-10 | Equateq Ltd | Novel methods |
| HRP20171691T1 (hr) | 2009-06-05 | 2017-12-15 | Allergan, Inc. | Umjetne suze i njihova upotreba u terapiji |
| WO2011103510A1 (en) * | 2010-02-18 | 2011-08-25 | Martek Biosciences Corporation | Dha ester emulsions |
| US20110200645A1 (en) * | 2010-02-18 | 2011-08-18 | Martek Biosciences Corporation | DHA Free Fatty Acid Emulsions |
| WO2011103514A1 (en) * | 2010-02-18 | 2011-08-25 | Martek Biosciences Corporation | Dha triglyceride emulsions |
| IN2012DN06581A (enExample) | 2010-03-17 | 2015-10-23 | Novaliq Gmbh | |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| DE102010050570A1 (de) | 2010-11-05 | 2012-05-10 | F. Holzer Gmbh | Zusammensetzung und Arzneimittel enthaltend ω-3-Fettsäuren sowie einen Inhibitor des NF-κB-Transkriptionsfaktors |
| EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
| WO2012067224A1 (ja) * | 2010-11-19 | 2012-05-24 | 日本水産株式会社 | 角膜上皮障害及び/又は結膜上皮障害の治療又は予防剤 |
| WO2012145119A2 (en) * | 2011-04-17 | 2012-10-26 | Michael Gurin | Low inflammatory blended oils |
| KR101773648B1 (ko) | 2011-05-25 | 2017-08-31 | 노바리크 게엠베하 | 조갑에 투여를 위한 제약학적 조성물 |
| JP6039145B2 (ja) | 2011-05-25 | 2016-12-07 | ノバリック ゲーエムベーハー | 半フッ化アルカンを基礎にした局所薬学的組成物 |
| US10383839B2 (en) | 2011-06-30 | 2019-08-20 | Johnson & Johnson Vision Care, Inc. | Esters for treatment of ocular inflammatory conditions |
| US20160310456A1 (en) * | 2013-03-12 | 2016-10-27 | Physicians Recommended Nutriceuticals, Llc | Compositions and methods for using same for reducing levels of arachidonic acid in tissue having undergone an invasive procedure |
| US9381183B2 (en) * | 2012-07-18 | 2016-07-05 | Physicians Recommended Nutriceuticals, Llc | Methods for improving the quality of the meibum composition of meibomian glands |
| AU2012307524B2 (en) * | 2011-09-12 | 2016-10-20 | Tassos GEORGIOU | Use of omega fatty acids for treating disease |
| US8957048B2 (en) * | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
| US8293790B2 (en) | 2011-10-19 | 2012-10-23 | Dignity Sciences Limited | Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof |
| PT2806886T (pt) | 2012-01-23 | 2017-03-24 | Novaliq Gmbh | Composições de proteínas estabilizadas baseadas em alcanos semifluorados |
| US20160228397A1 (en) | 2012-03-30 | 2016-08-11 | Sancilio & Company, Inc. | Omega-3 fatty acid ester compositions |
| US9480651B2 (en) | 2012-03-30 | 2016-11-01 | Sancilio & Company, Inc. | Omega-3 fatty acid ester compositions unitary pharmaceutical dosage forms |
| HK1204978A1 (zh) | 2012-03-30 | 2015-12-11 | 桑茨利奥&孔帕尼股份有限公司 | ω-3脂肪酸酯组合物 |
| US10898458B2 (en) | 2012-03-30 | 2021-01-26 | Micelle Biopharma, Inc. | Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states |
| EP2664330A1 (de) | 2012-05-15 | 2013-11-20 | F. Holzer GmbH | Zusammensetzung und Arzneimittel enthaltend Omega-3-Fettsäuren sowie einen Glucosaminoglucan |
| CN104602670A (zh) * | 2012-08-31 | 2015-05-06 | 博士伦公司 | 含有ω-3 脂肪酸的眼用组合物 |
| US8673325B1 (en) * | 2012-09-06 | 2014-03-18 | Dignity Sciences Limited | Cosmetic compositions comprising EPA and salicylic acid and methods of making and using same |
| CN113952321B (zh) | 2012-09-12 | 2023-03-28 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| EP3181119B1 (en) * | 2012-09-12 | 2019-07-10 | Novaliq GmbH | Semifluorinated alkane compositions for use in the treatment of keratoconjunctivitis sicca |
| GB201301626D0 (en) | 2013-01-30 | 2013-03-13 | Dignity Sciences Ltd | Composition comprising 15-OHEPA and methods of using the same |
| AU2014222417B2 (en) | 2013-02-26 | 2017-09-07 | Belkin Vision Ltd. | System for glaucoma treatment |
| PT3024484T (pt) | 2013-07-23 | 2018-10-24 | Novaliq Gmbh | Composições de anticorpo estabilizadas |
| US20150080329A1 (en) * | 2013-09-19 | 2015-03-19 | Dignity Sciences Limited | Pharmaceutical compositions comprising dha, epa, and/or gla and an antibiotic agent and methods of use thereof |
| EP3151825B1 (en) | 2014-06-04 | 2020-03-25 | DS Biopharma Limited | Pharmaceutical compositions comprising dgla and use of same |
| RU2697844C9 (ru) | 2014-11-25 | 2019-10-01 | Аллерган, Инк. | Стабилизированные композиции для офтальмологического применения, содержащие омега-3-кислоты |
| WO2016094876A1 (en) * | 2014-12-12 | 2016-06-16 | The Schepens Eye Research Institute, Inc. | Gdnf induction for the treatment of retinal disorders |
| HK1250345A1 (zh) | 2015-05-13 | 2018-12-14 | Afimmune Limited | 包含15-氧代-epa或15-氧代-dgla的组合物及其制备和使用方法 |
| EP3861995A1 (en) | 2015-07-21 | 2021-08-11 | Affimune Limited | Compositions comprising 15-hepe for use in treating or preventing neurologic disease |
| CN111743882A (zh) | 2015-09-30 | 2020-10-09 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| PT3356313T (pt) | 2015-09-30 | 2020-07-13 | Novaliq Gmbh | 2-perfluoro-hexiloctano para administração oftálmica |
| BR122023026625A2 (pt) | 2015-12-18 | 2024-01-16 | Afimmune Limited | Uso do ácido 15-hidroxieicosapentaenoico ou derivados farmaceuticamente aceitáveis do mesmo |
| CN106963728A (zh) * | 2016-01-13 | 2017-07-21 | 汤欣 | 一种二十二碳六烯酸结膜下注射液的制备方法及其应用 |
| CN109640900B (zh) | 2016-06-23 | 2020-07-07 | 诺瓦利克有限责任公司 | 一种试剂盒 |
| CN109890374A (zh) | 2016-09-22 | 2019-06-14 | 诺瓦利克有限责任公司 | 用于治疗睑缘炎的药物组合物 |
| US10813976B2 (en) | 2016-09-23 | 2020-10-27 | Novaliq Gmbh | Ophthalmic compositions comprising ciclosporin |
| KR102288022B1 (ko) | 2016-12-23 | 2021-08-10 | 노바리크 게엠베하 | 건성 안 질환 치료용 안구 조성물 |
| MX388460B (es) | 2017-04-21 | 2025-03-20 | Dermaliq Therapeutics Inc | Composiciones de yodo. |
| CN110650734B (zh) | 2017-05-12 | 2024-11-15 | 诺瓦利克有限责任公司 | 治疗与隐形眼镜有关病症的包含半氟化烷烃的药物组合物 |
| KR20200059272A (ko) | 2017-09-27 | 2020-05-28 | 노바리크 게엠베하 | 안구 질환의 치료에서의 사용을 위한 라타노프로스트를 포함하는 안과적 조성물 |
| WO2019068763A1 (en) | 2017-10-04 | 2019-04-11 | Novaliq Gmbh | OPHTHALMIC COMPOSITIONS COMPRISING F6H8 |
| CA3091308A1 (en) | 2018-03-02 | 2019-09-06 | Novaliq Gmbh | Pharmaceutical compositions comprising nebivolol |
| CN112153970A (zh) | 2018-04-27 | 2020-12-29 | 诺瓦利克有限责任公司 | 用于治疗青光眼的包含他氟前列素的眼用组合物 |
| NO345574B1 (en) | 2018-06-19 | 2021-04-26 | Epax Norway As | Composition for treatment of dry eye disease and meibomianitis |
| SG11202102820VA (en) | 2018-10-12 | 2021-04-29 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
| CN113710228A (zh) | 2019-02-13 | 2021-11-26 | 诺瓦利克有限责任公司 | 用于治疗眼部新生血管形成的组合物和方法 |
| EP4093372B1 (en) * | 2020-01-23 | 2024-04-03 | Visufarma S.p.A. | Ophthalmic composition for the treatment of dry eye disease |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
Family Cites Families (113)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US437014A (en) * | 1890-09-23 | Swing | ||
| US3572913A (en) * | 1969-02-03 | 1971-03-30 | Boylston Res Ass | Comprehensive support for ophthalmic examination apparatus and instruments |
| US4056496A (en) * | 1972-10-02 | 1977-11-01 | Corneal Sciences, Inc. | Hydrogels and articles made therefrom |
| US3957362A (en) * | 1972-10-02 | 1976-05-18 | Corneal Sciences, Inc. | Hydrogels and articles made therefrom |
| US4180308A (en) * | 1972-10-02 | 1979-12-25 | Syntex (Usa) Inc. | Contact lens |
| US4401372A (en) * | 1972-10-02 | 1983-08-30 | Syntex (U.S.A.) Inc. | Contact lens |
| DE2309440A1 (de) * | 1973-02-26 | 1974-09-05 | Katz | Verfahren zum isolieren von lysozym |
| US3991759A (en) | 1975-10-28 | 1976-11-16 | Alza Corporation | Method and therapeutic system for treating aqueous deficient dry eye |
| US4313355A (en) * | 1978-02-06 | 1982-02-02 | Syntex (U.S.A.) Inc. | Method and apparatus for manufacturing plastic lenses |
| US4202226A (en) * | 1978-02-06 | 1980-05-13 | SyntexLaboratories, Inc. | Method and apparatus for manufacturing plastic lenses |
| US4379864A (en) * | 1979-02-09 | 1983-04-12 | Syntex (U.S.A.) Inc. | Polymeric compositions and hydrogels formed therefrom |
| US4338419A (en) * | 1979-02-09 | 1982-07-06 | Syntex (U.S.A.) Inc. | Process for treatment of hydrogel lens with thiols |
| US4267295A (en) * | 1979-02-09 | 1981-05-12 | Syntex (U.S.A.) Inc. | Polymeric compositions and hydrogels formed therefrom |
| US4543371A (en) * | 1981-03-05 | 1985-09-24 | Syntex (U.S.A.) Inc. | Polymeric compositions and hydrogels formed therefrom |
| US5145686A (en) * | 1982-02-03 | 1992-09-08 | Efamol Limited | Topical pharmaceutical compositions |
| DE3368377D1 (en) | 1982-04-16 | 1987-01-29 | Nestle Sa | Lipid composition for oral, enteral or parenteral feeding |
| US4421748A (en) * | 1982-07-13 | 1983-12-20 | Trager Seymour F | Artificial tear aid |
| US4622258A (en) * | 1983-04-12 | 1986-11-11 | Minnesota Mining And Manufacturing Company | Contact lens cleaning article |
| US4533399A (en) * | 1983-04-12 | 1985-08-06 | Minnesota Mining And Manufacturing Company | Contact lens cleaning method |
| US4678698A (en) * | 1983-04-12 | 1987-07-07 | Minnesota Mining And Manufacturing Company | Contact lens cleaning article |
| JPS6158539A (ja) * | 1984-08-29 | 1986-03-25 | Nisshin Oil Mills Ltd:The | スナツク様菓子の製造法 |
| US4613380A (en) * | 1985-04-01 | 1986-09-23 | Dow Corning Corporation | Method for removing lipid deposits from contact lenses |
| US5484432A (en) * | 1985-09-27 | 1996-01-16 | Laser Biotech, Inc. | Collagen treatment apparatus |
| GB8524275D0 (en) * | 1985-10-02 | 1985-11-06 | Efamol Ltd | Pharmaceutical & dietary compositions |
| US5032394A (en) * | 1986-05-15 | 1991-07-16 | Emory University | Method of treating burns |
| US5080894A (en) * | 1986-05-15 | 1992-01-14 | Emory University | Method and composition for reducing tissue damage |
| US4879109A (en) * | 1986-05-15 | 1989-11-07 | Emory University | Method for treating burns |
| US5071649A (en) * | 1986-05-15 | 1991-12-10 | Emory University | Method of preventing blockage in catheters |
| US5089260A (en) * | 1986-05-15 | 1992-02-18 | Emory University | Method of treating ischemic tissue |
| US5240701A (en) * | 1986-05-15 | 1993-08-31 | Emory University | Method of performing angioplasty procedures |
| US5039520A (en) * | 1986-05-15 | 1991-08-13 | Emory University | Plasma extender |
| US4897263A (en) * | 1986-05-15 | 1990-01-30 | Emory University | Methods and compositions for treatment of pathological hydrophobic interactions in biological fluids |
| US4837014A (en) * | 1986-05-15 | 1989-06-06 | Emory University | An improved method of treating sickle cell anemia |
| US5028599A (en) * | 1986-05-15 | 1991-07-02 | Emory University | Method of treating mycardial damage |
| US5030448A (en) * | 1986-05-15 | 1991-07-09 | Emory University | Method of delivering drugs to damaged or diseased tissue |
| US5064643A (en) * | 1986-05-15 | 1991-11-12 | Emory University | Method for treating sickle cell disease |
| US5047236A (en) * | 1986-05-15 | 1991-09-10 | Emory University | Method of treating stroke |
| US4997644A (en) * | 1986-05-15 | 1991-03-05 | Emory University | Method of treating adult respiratory distress syndrome |
| US5198211A (en) * | 1986-05-15 | 1993-03-30 | Emory University | Method of treating myocardial damage |
| US4937070A (en) * | 1986-05-15 | 1990-06-26 | Emory University | Methods and compositions for treatment of pathological hydrophobic interactions in biological fluids |
| US5250294A (en) * | 1986-05-15 | 1993-10-05 | Emory University | Improved perfusion medium for transplantation of organs |
| US5078995A (en) * | 1986-05-15 | 1992-01-07 | Emory University | Fibrionolytic composition |
| US5041288A (en) * | 1986-05-15 | 1991-08-20 | Emory University | Method of treating tissue damaged by reperfusion injury |
| US5648071A (en) * | 1986-05-15 | 1997-07-15 | Emory University | Method of treating tumors |
| US5017370A (en) * | 1986-05-15 | 1991-05-21 | Emory University | Improved method of performing angioplasty procedures |
| US5240702A (en) * | 1986-05-15 | 1993-08-31 | Emory University | Method of treating stroke |
| US4801452A (en) * | 1986-05-15 | 1989-01-31 | Hunter Robert L | Fibrinolytic composition |
| US5182106A (en) * | 1986-05-15 | 1993-01-26 | Emory University | Method for treating hypothermia |
| US5278151A (en) * | 1987-04-02 | 1994-01-11 | Ocular Research Of Boston, Inc. | Dry eye treatment solution |
| US4914088A (en) * | 1987-04-02 | 1990-04-03 | Thomas Glonek | Dry eye treatment solution and method |
| US5252333A (en) * | 1987-04-27 | 1993-10-12 | Scotia Holdings Plc | Lithium salt-containing pharmaceutical compositions |
| GB8710780D0 (en) | 1987-05-07 | 1987-06-10 | Scras | Opthalmological application of eicosapentaenoic acid |
| CA1263270A (en) * | 1987-08-19 | 1989-11-28 | Bruce J. Holub | Animal feed supplement |
| US5111221A (en) * | 1988-05-13 | 1992-05-05 | United States Of America As Represented By The Secretary Of The Navy | Receptor-based sensor |
| US5225374A (en) * | 1988-05-13 | 1993-07-06 | The United States Of America As Represented By The Secretary Of The Navy | Method of fabricating a receptor-based sensor |
| US4923700A (en) * | 1988-06-03 | 1990-05-08 | Kaufman Herbert E | Artificial tear suspension |
| US4959048A (en) * | 1989-01-17 | 1990-09-25 | Helix Medical, Inc. | Lacrimal duct occluder |
| US5182258A (en) * | 1989-03-20 | 1993-01-26 | Orbon Corporation | Systemic delivery of polypeptides through the eye |
| US5278142A (en) * | 1989-03-20 | 1994-01-11 | Orbon Corporation | Systemic delivery of polypeptides through the eye |
| US5174988A (en) * | 1989-07-27 | 1992-12-29 | Scientific Development & Research, Inc. | Phospholipid delivery system |
| US5206298A (en) * | 1989-12-19 | 1993-04-27 | Tomei Sangyo Kabushiki Kaisha | Graft copolymer, solution containing the graft copolymer for treating contact lens, and method of treating contact lens with the solution and making hydrophilic lens surface |
| ZA912797B (en) * | 1990-05-29 | 1992-12-30 | Boston Ocular Res | Dry eye treatment process and solution |
| EP0459148B1 (en) * | 1990-05-29 | 1996-01-03 | Ocular Research Of Boston Inc. | Dry eye treatment composition |
| US5167323A (en) * | 1990-08-09 | 1992-12-01 | Tomei Sangyo Co., Ltd. | Lens treating device for treating contact lens |
| US5181604A (en) * | 1990-09-14 | 1993-01-26 | Tomei Sangyo Co., Ltd. | Contact lens holder and treating device |
| US5203337A (en) * | 1991-05-08 | 1993-04-20 | Brigham And Women's Hospital, Inc. | Coronary artery imaging system |
| ZA927277B (en) * | 1991-10-02 | 1993-05-19 | Boston Ocular Res | Dry eye treatment process and solution. |
| US5469867A (en) * | 1992-09-02 | 1995-11-28 | Landec Corporation | Cast-in place thermoplastic channel occluder |
| PH30249A (en) * | 1992-09-16 | 1997-02-05 | Zhejiang Provincial Hospital O | Neutral lipids from endosperm of job's tears |
| JPH06122627A (ja) * | 1992-10-13 | 1994-05-06 | Sagami Chem Res Center | 抗アレルギー点眼液 |
| US5378488A (en) * | 1993-06-10 | 1995-01-03 | Abbott Laboratories | Aseptic processing of infant formula |
| JPH09507513A (ja) * | 1993-12-29 | 1997-07-29 | ボシュ アンド ロム インコーポレイテッド | コンタクトレンズを洗浄および消毒するための炭水化物組成物および方法 |
| US6060644A (en) * | 1994-03-24 | 2000-05-09 | Iowa State University Research Foundation, Inc. | Isolation and use of cuticular lipid genes |
| US5474979A (en) | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| US6113894A (en) * | 1995-01-23 | 2000-09-05 | Smith; S. Gregory | Ophthalmic compositions and process of using |
| US5861148A (en) * | 1995-01-23 | 1999-01-19 | Smith; Stewart Gregory | Ophthalmic compositions and process of using |
| DE69629230D1 (de) * | 1995-03-24 | 2003-09-04 | Ocular Res Of Bonton Inc | Hydrogellinse mit Lipid-Vorbeschichtigung |
| US5738856A (en) * | 1995-11-03 | 1998-04-14 | Ocular Research Of Boston, Inc. | Skin care preparation and method |
| WO1997020578A1 (en) * | 1995-12-04 | 1997-06-12 | University Of Miami | Non-preserved topical corticosteroid for treatment of dry eye, filamentary keratitis, and delayed tear clearance |
| DK0915693T3 (da) * | 1996-08-02 | 2004-02-09 | Plum Kemi Produktion As | En olie-i-vand emulsion til brug på menneskers hud for at rengøre, beskytte eller forbedre hudens tilstand |
| SK66198A3 (en) * | 1996-09-20 | 1999-09-10 | Atherogenics Inc | Diagnostics for and mediators of inflammatory disorders |
| US6475789B1 (en) * | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| JPH10218760A (ja) | 1997-02-04 | 1998-08-18 | Nobel Igaku Kenkyusho:Kk | ドライアイ治療用の微量油添加目薬 |
| AP2000001969A0 (en) * | 1997-03-03 | 2000-12-31 | Adcock Ingram Ltd | A composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the prevention, treatment and diagnosis of disease. |
| WO1999011692A1 (en) * | 1997-09-03 | 1999-03-11 | The Regents Of The University Of California | Novel biomimetic hydrogel materials |
| US6475784B1 (en) * | 1997-11-14 | 2002-11-05 | Valentis, Inc. | Inhibition of angiogenesis by delivery of nucleic acids encoding anti-angiogenic polypeptides |
| US5981607A (en) * | 1998-01-20 | 1999-11-09 | Allergan | Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers |
| CN1175904C (zh) | 1998-05-15 | 2004-11-17 | 若素制药株式会社 | 抗炎滴眼剂 |
| US6346594B1 (en) * | 1998-09-21 | 2002-02-12 | Menicon Co., Ltd. | Ocular lens material and process for producing same |
| US6429194B1 (en) * | 1999-03-01 | 2002-08-06 | Vista Scientific Llc | Mucin containing ophthalmic preparation |
| CA2362498A1 (en) * | 1999-03-01 | 2000-09-08 | Vista Scientific Llc | Mucin containing ophthalmic preparations |
| US6428502B1 (en) * | 1999-06-25 | 2002-08-06 | Alcon Manufacturing, Ltd. | Punctal cannula |
| TWI225398B (en) * | 1999-07-14 | 2004-12-21 | R Tech Ueno Ltd | Composition for treatment of external secretion disorders |
| AUPQ228199A0 (en) | 1999-08-18 | 1999-09-09 | Sly, Anthony William | Ophthalmic fluid |
| WO2001028519A1 (de) * | 1999-10-20 | 2001-04-26 | Vesifact Ag | Mikroemulsion-prekonzentrate und mikroemulsionen |
| US6286955B1 (en) * | 1999-12-15 | 2001-09-11 | Tetsuya Sakai | Biocompatible lens, and method of producing the same |
| US6344047B1 (en) * | 2000-02-02 | 2002-02-05 | Eagle Vision | Instrument for inserting a punctum plug and method for manufacturing the instrument |
| US6533415B2 (en) * | 2000-03-21 | 2003-03-18 | Menicon Co., Ltd. | Ocular lens material having hydrophilic surface and process for preparing the same |
| GB0012597D0 (en) * | 2000-05-25 | 2000-07-12 | Astrazeneca Ab | Formulation |
| AU2001283068A1 (en) * | 2000-08-01 | 2002-02-13 | Ocular Research Of Boston, Inc. | Visual discomfort relief |
| US6506412B2 (en) * | 2000-11-29 | 2003-01-14 | Sciencebased Health | Treatment of dry eye syndrome |
| US6667047B2 (en) * | 2001-07-27 | 2003-12-23 | International Flute Technologies Ltd | Ultra-stable composition comprising moringa oil and its derivatives and uses thereof |
| WO2003018049A2 (en) * | 2001-08-23 | 2003-03-06 | Westgate Biological Limited | Use of milk serum apoproteins in the prophylaxis or treatment of microbial or viral infection |
| US20040076691A1 (en) | 2002-01-16 | 2004-04-22 | David Haines | Anti-inflammatory formulations |
| US20040048926A1 (en) * | 2002-03-15 | 2004-03-11 | Hoffman Dennis Robert | Use of docosahexaenoic acid and arachidonic acid to enhance the visual development of term infants breast-fed up to the age of six months |
| AU2003238240A1 (en) * | 2002-06-17 | 2003-12-31 | Resolvyx Pharmaceuticals | ANALOGUES OF LIPID MEDIATORS DERIVED FROM OMEGA-3 PUFAs AND METHODS OF USE |
| US20040076695A1 (en) * | 2002-07-08 | 2004-04-22 | Advanced Vision Research | EPA and DHA enriched omega-3 supplement for the treatment of dry eye, meibomianitis and xerostomia |
| WO2004006801A2 (en) | 2002-07-17 | 2004-01-22 | Biosyntrx, Inc. | Treatment for dry eye syndrome |
| US20060251685A1 (en) * | 2003-03-18 | 2006-11-09 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with Omega-3 fatty acids for alleviating dry eye |
| US20040185068A1 (en) * | 2003-03-18 | 2004-09-23 | Zhi-Jian Yu | Self-emulsifying compositions, methods of use and preparation |
| US20050255144A1 (en) * | 2003-04-09 | 2005-11-17 | Directcontact Llc | Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases |
| JP2005008570A (ja) * | 2003-06-19 | 2005-01-13 | Santen Pharmaceut Co Ltd | 角膜疾患治療剤 |
| US20050202097A1 (en) * | 2004-03-12 | 2005-09-15 | Melbj Holdings, Llc, Florida | Lubricant for the ocular surface |
-
2005
- 2005-06-30 CN CNA2005800287299A patent/CN101043884A/zh active Pending
- 2005-06-30 CA CA002572344A patent/CA2572344A1/en not_active Abandoned
- 2005-06-30 AU AU2005262392A patent/AU2005262392A1/en not_active Abandoned
- 2005-06-30 KR KR1020077002456A patent/KR20070040381A/ko not_active Withdrawn
- 2005-06-30 EP EP05767809.6A patent/EP1781278B2/en not_active Expired - Lifetime
- 2005-06-30 BR BRPI0512864A patent/BRPI0512864B8/pt not_active IP Right Cessation
- 2005-06-30 US US11/171,815 patent/US20060009522A1/en not_active Abandoned
- 2005-06-30 MX MX2007000208A patent/MX2007000208A/es not_active Application Discontinuation
- 2005-06-30 RU RU2007103835/15A patent/RU2007103835A/ru not_active Application Discontinuation
- 2005-06-30 NZ NZ552481A patent/NZ552481A/en unknown
- 2005-06-30 WO PCT/US2005/023113 patent/WO2006007510A1/en not_active Ceased
- 2005-06-30 JP JP2007520365A patent/JP2008505177A/ja active Pending
-
2006
- 2006-12-26 IL IL180342A patent/IL180342A0/en unknown
-
2007
- 2007-01-30 NO NO20070561A patent/NO20070561L/no not_active Application Discontinuation
- 2007-01-31 ZA ZA200700918A patent/ZA200700918B/xx unknown
- 2007-10-17 US US11/873,478 patent/US20080153909A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006007510A1 (en) | 2006-01-19 |
| ZA200700918B (en) | 2008-10-29 |
| IL180342A0 (en) | 2007-07-04 |
| BRPI0512864B8 (pt) | 2021-05-25 |
| JP2008505177A (ja) | 2008-02-21 |
| MX2007000208A (es) | 2007-08-07 |
| CN101043884A (zh) | 2007-09-26 |
| AU2005262392A1 (en) | 2006-01-19 |
| EP1781278A1 (en) | 2007-05-09 |
| EP1781278A4 (en) | 2009-09-02 |
| NZ552481A (en) | 2008-12-24 |
| BRPI0512864B1 (pt) | 2021-04-27 |
| US20080153909A1 (en) | 2008-06-26 |
| KR20070040381A (ko) | 2007-04-16 |
| NO20070561L (no) | 2007-03-30 |
| US20060009522A1 (en) | 2006-01-12 |
| BRPI0512864A (pt) | 2008-04-08 |
| RU2007103835A (ru) | 2008-08-10 |
| EP1781278B1 (en) | 2016-08-10 |
| EP1781278B2 (en) | 2019-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1781278B2 (en) | Compositions and methods for treating eye disorders and conditions | |
| US20070265341A1 (en) | Compositions and methods for treating eye disorders and conditions | |
| KR101677308B1 (ko) | 오메가-3 및 오메가-6 다가 불포화 지방산계 안과용 조성물 | |
| CA2840152C (en) | Esters for treatment of ocular inflammatory conditions | |
| CN103533962A (zh) | 一种眼用组合物 | |
| TW202535338A (zh) | 基於脂質的眼用乳劑 | |
| JP2022506684A (ja) | 人工涙液 | |
| EP3280395B1 (en) | Ophthalmic compositions based on polyunsaturated fatty acids and triacylglycerols | |
| US20220031625A1 (en) | Ophthalmic compositions for delivering meibum-like materials | |
| WO2023055321A1 (en) | Anti-inflammatory microemulsion eye formulations derived from nigella sativa oil | |
| HK1166714B (en) | Ophthalmic compositions based on polyunsaturated omega-3 and omega-6 fatty acids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20130703 |