JP2008503716A5 - - Google Patents
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- Publication number
- JP2008503716A5 JP2008503716A5 JP2007516078A JP2007516078A JP2008503716A5 JP 2008503716 A5 JP2008503716 A5 JP 2008503716A5 JP 2007516078 A JP2007516078 A JP 2007516078A JP 2007516078 A JP2007516078 A JP 2007516078A JP 2008503716 A5 JP2008503716 A5 JP 2008503716A5
- Authority
- JP
- Japan
- Prior art keywords
- serotype
- conjugate
- sugar
- batch
- molecular weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001720 carbohydrates Chemical class 0.000 claims 12
- 241000588650 Neisseria meningitidis Species 0.000 claims 8
- 229960005486 vaccine Drugs 0.000 claims 6
- 229920000642 polymer Polymers 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0413868.1A GB0413868D0 (en) | 2004-06-21 | 2004-06-21 | Dimensional anlaysis of saccharide conjugates |
| PCT/IB2005/002532 WO2006000920A2 (en) | 2004-06-21 | 2005-06-21 | Dimensional analysis of saccharide conjugates with gpc & sec-mals |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011192126A Division JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008503716A JP2008503716A (ja) | 2008-02-07 |
| JP2008503716A5 true JP2008503716A5 (https=) | 2008-07-17 |
Family
ID=32750313
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516078A Withdrawn JP2008503716A (ja) | 2004-06-21 | 2005-06-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2011192126A Withdrawn JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2014047555A Expired - Lifetime JP6218327B2 (ja) | 2004-06-21 | 2014-03-11 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2015143718A Pending JP2015180707A (ja) | 2004-06-21 | 2015-07-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2017084454A Expired - Lifetime JP6661568B2 (ja) | 2004-06-21 | 2017-04-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011192126A Withdrawn JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2014047555A Expired - Lifetime JP6218327B2 (ja) | 2004-06-21 | 2014-03-11 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2015143718A Pending JP2015180707A (ja) | 2004-06-21 | 2015-07-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2017084454A Expired - Lifetime JP6661568B2 (ja) | 2004-06-21 | 2017-04-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8163296B2 (https=) |
| EP (2) | EP2374473B1 (https=) |
| JP (5) | JP2008503716A (https=) |
| CN (1) | CN1976725B (https=) |
| AU (1) | AU2005256961B2 (https=) |
| BR (1) | BRPI0512281A (https=) |
| CA (1) | CA2571565C (https=) |
| ES (2) | ES2688796T3 (https=) |
| GB (1) | GB0413868D0 (https=) |
| MX (2) | MXPA06015188A (https=) |
| NZ (1) | NZ552449A (https=) |
| RU (1) | RU2422156C2 (https=) |
| WO (1) | WO2006000920A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0413868D0 (en) * | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
| US8398983B2 (en) | 2005-06-27 | 2013-03-19 | Glaxosmithkline Biologicals, S.A. | Immunogenic composition |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| TW201009337A (en) * | 2008-05-30 | 2010-03-01 | Intervet Int Bv | Analytical method to monitor vaccine potency and stability |
| JP6151021B2 (ja) | 2009-06-01 | 2017-06-21 | ウオーターズ・テクノロジーズ・コーポレイシヨン | クロマトグラフ分離用ハイブリッド材料 |
| US8195405B2 (en) * | 2009-06-30 | 2012-06-05 | Wyatt Technology Corporation | Method for characterizing reversible association of macromolecules at high concentration |
| BR112012010223A2 (pt) | 2009-10-30 | 2016-12-06 | Novartis Ag | purificação de staphylococcus aureus tipo 5 e tipo 8 sacarídeos capsulares |
| CN109078626A (zh) * | 2009-12-15 | 2018-12-25 | 沃特世科技公司 | 实施体积排阻色谱的设备和方法 |
| AU2011258165B2 (en) * | 2010-05-26 | 2016-11-17 | Selecta Biosciences, Inc. | Dose selection of adjuvanted synthetic nanocarriers |
| JP5856162B2 (ja) | 2010-07-26 | 2016-02-09 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 粒度分布の狭い実質的に非多孔質のハイブリッドコアを含む表面多孔質材料 |
| KR101594228B1 (ko) | 2010-08-23 | 2016-02-15 | 와이어쓰 엘엘씨 | 네이세리아 메닌기티디스 ｒＬＰ２０８６ 항원의 안정한 제제 |
| NZ607224A (en) | 2010-09-10 | 2014-11-28 | Wyeth Llc | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
| MX359256B (es) | 2012-03-09 | 2018-09-19 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas. |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| US10481164B2 (en) | 2012-03-26 | 2019-11-19 | Amgen Inc. | Method for using light scattering in real time to directly monitor and control impurity removal in purification processes |
| US9802987B2 (en) | 2013-03-08 | 2017-10-31 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| KR102906912B1 (ko) | 2016-09-02 | 2026-01-05 | 사노피 파스퇴르 인크 | 네이세리아 메닌기티디스 백신 |
| ES3024474T3 (en) | 2016-12-30 | 2025-06-04 | Vaxcyte Inc | Polypeptide-antigen conjugates with non-natural amino acids |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| CN109459523B (zh) * | 2017-09-06 | 2022-11-08 | 上海绿谷制药有限公司 | 一种测定酸性糖可溶性盐重均分子量和含量的方法 |
| CN109459504B (zh) * | 2017-09-06 | 2022-05-27 | 绿谷(上海)医药科技有限公司 | 一种测定聚古罗糖醛酸硫酸酯盐重均分子量和含量的方法 |
| EP4034157A1 (en) | 2019-09-27 | 2022-08-03 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| JP7409055B2 (ja) * | 2019-12-05 | 2024-01-09 | 株式会社島津製作所 | 検出器の出力を補正する方法、および多角度光散乱検出器 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4057685A (en) | 1972-02-02 | 1977-11-08 | Abbott Laboratories | Chemically modified endotoxin immunizing agent |
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4459286A (en) | 1983-01-31 | 1984-07-10 | Merck & Co., Inc. | Coupled H. influenzae type B vaccine |
| US4663160A (en) | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
| US4761283A (en) | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| US4808700A (en) | 1984-07-09 | 1989-02-28 | Praxis Biologics, Inc. | Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers |
| JPH01125328A (ja) | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | 髄膜炎菌ワクチン |
| NL8802046A (nl) | 1988-08-18 | 1990-03-16 | Gen Electric | Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen. |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| EP0378881B1 (en) | 1989-01-17 | 1993-06-09 | ENIRICERCHE S.p.A. | Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines |
| WO1991001146A1 (en) | 1989-07-14 | 1991-02-07 | Praxis Biologics, Inc. | Cytokine and hormone carriers for conjugate vaccines |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| IL98715A0 (en) | 1990-08-13 | 1992-07-15 | American Cyanamid Co | Filamentous hemaglutinin of bodetella pertussis as a carrier molecule for conjugate vaccines |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| TR199701547T1 (xx) | 1995-06-07 | 1998-03-21 | Smithkline Beecham Biologicals S.A. | Polisakarit antijen protein e�leni�i i�eren a��. |
| US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| US7018637B2 (en) * | 1998-02-23 | 2006-03-28 | Aventis Pasteur, Inc | Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines |
| JP2004505885A (ja) | 1998-08-19 | 2004-02-26 | ノース アメリカン ワクチン， インコーポレイテッド | Ｎ−アクリロイル化ポリサッカリドを用いて産生されたワクチンとして有用な免疫原性β−プロピオンアミド連結ポリサッカリド−タンパク質結合体 |
| ES2275499T3 (es) | 1999-03-19 | 2007-06-16 | Glaxosmithkline Biologicals S.A. | Vacuna contra streptococcus pneumoniae. |
| WO2000061761A2 (en) | 1999-04-09 | 2000-10-19 | Techlab, Inc. | Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines |
| PT2289545T (pt) | 2000-01-17 | 2016-09-06 | Glaxosmithkline Biologicals Sa | Vacina de omv suplementada contra meningococos |
| GB0007432D0 (en) | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| US6936261B2 (en) | 2000-07-27 | 2005-08-30 | Children's Hospital & Research Center At Oakland | Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
| GB0103170D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| OA12590A (en) * | 2001-01-23 | 2006-06-08 | Aventis Pasteur | Multivalent meningococcal polysaccharide-protein conjugate vaccine. |
| AU2002309706A1 (en) | 2001-05-11 | 2002-11-25 | Aventis Pasteur, Inc. | Novel meningitis conjugate vaccine |
| GB0115176D0 (en) * | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| HUE031886T2 (en) * | 2002-10-11 | 2017-08-28 | Glaxosmithkline Biologicals Sa | Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines |
| ES2461350T3 (es) * | 2003-01-30 | 2014-05-19 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| CN103357002A (zh) * | 2003-10-02 | 2013-10-23 | 诺华疫苗和诊断有限公司 | 多种脑膜炎球菌血清群的液体疫苗 |
| GB0408978D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Meningococcal fermentation for preparing conjugate vaccines |
| GB0413868D0 (en) * | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
-
2004
- 2004-06-21 GB GBGB0413868.1A patent/GB0413868D0/en not_active Ceased
-
2005
- 2005-06-21 JP JP2007516078A patent/JP2008503716A/ja not_active Withdrawn
- 2005-06-21 EP EP11163751.8A patent/EP2374473B1/en not_active Expired - Lifetime
- 2005-06-21 AU AU2005256961A patent/AU2005256961B2/en not_active Expired
- 2005-06-21 ES ES11163751.8T patent/ES2688796T3/es not_active Expired - Lifetime
- 2005-06-21 NZ NZ552449A patent/NZ552449A/en not_active IP Right Cessation
- 2005-06-21 WO PCT/IB2005/002532 patent/WO2006000920A2/en not_active Ceased
- 2005-06-21 US US11/630,545 patent/US8163296B2/en active Active
- 2005-06-21 BR BRPI0512281-3A patent/BRPI0512281A/pt not_active Application Discontinuation
- 2005-06-21 ES ES05770612.9T patent/ES2443465T3/es not_active Expired - Lifetime
- 2005-06-21 CN CN2005800204436A patent/CN1976725B/zh not_active Expired - Lifetime
- 2005-06-21 RU RU2007102016/15A patent/RU2422156C2/ru active IP Right Revival
- 2005-06-21 CA CA2571565A patent/CA2571565C/en not_active Expired - Lifetime
- 2005-06-21 EP EP05770612.9A patent/EP1778291B1/en not_active Expired - Lifetime
- 2005-06-21 MX MXPA06015188A patent/MXPA06015188A/es active IP Right Grant
-
2006
- 2006-12-20 MX MX2011011568A patent/MX344621B/es unknown
-
2011
- 2011-09-02 JP JP2011192126A patent/JP2011246490A/ja not_active Withdrawn
-
2012
- 2012-04-24 US US13/454,658 patent/US20120207781A1/en not_active Abandoned
-
2014
- 2014-03-11 JP JP2014047555A patent/JP6218327B2/ja not_active Expired - Lifetime
-
2015
- 2015-07-21 JP JP2015143718A patent/JP2015180707A/ja active Pending
-
2017
- 2017-04-21 JP JP2017084454A patent/JP6661568B2/ja not_active Expired - Lifetime
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