JP2008503716A - Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 - Google Patents

Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 Download PDF

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JP2008503716A
JP2008503716A JP2007516078A JP2007516078A JP2008503716A JP 2008503716 A JP2008503716 A JP 2008503716A JP 2007516078 A JP2007516078 A JP 2007516078A JP 2007516078 A JP2007516078 A JP 2007516078A JP 2008503716 A JP2008503716 A JP 2008503716A
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serotype
conjugate
sugar
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JP2008503716A5 (enExample
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ジョルジオ カパンノリ，
バレリア カリンチ，
サンドロ ダセンツィ，
クラウディア マガノーリ，
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カイロン ソチエタ ア レスポンサビリタ リミタータ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Spectrometry And Color Measurement (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2007516078A 2004-06-21 2005-06-21 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 Withdrawn JP2008503716A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0413868.1A GB0413868D0 (en) 2004-06-21 2004-06-21 Dimensional anlaysis of saccharide conjugates
PCT/IB2005/002532 WO2006000920A2 (en) 2004-06-21 2005-06-21 Dimensional analysis of saccharide conjugates with gpc & sec-mals

Related Child Applications (1)

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JP2011192126A Division JP2011246490A (ja) 2004-06-21 2011-09-02 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析

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JP2008503716A true JP2008503716A (ja) 2008-02-07
JP2008503716A5 JP2008503716A5 (enExample) 2008-07-17

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JP2007516078A Withdrawn JP2008503716A (ja) 2004-06-21 2005-06-21 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析
JP2011192126A Withdrawn JP2011246490A (ja) 2004-06-21 2011-09-02 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析
JP2014047555A Expired - Lifetime JP6218327B2 (ja) 2004-06-21 2014-03-11 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析
JP2015143718A Pending JP2015180707A (ja) 2004-06-21 2015-07-21 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析
JP2017084454A Expired - Lifetime JP6661568B2 (ja) 2004-06-21 2017-04-21 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析

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JP2011192126A Withdrawn JP2011246490A (ja) 2004-06-21 2011-09-02 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析
JP2014047555A Expired - Lifetime JP6218327B2 (ja) 2004-06-21 2014-03-11 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析
JP2015143718A Pending JP2015180707A (ja) 2004-06-21 2015-07-21 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析
JP2017084454A Expired - Lifetime JP6661568B2 (ja) 2004-06-21 2017-04-21 Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析

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US (2) US8163296B2 (enExample)
EP (2) EP1778291B1 (enExample)
JP (5) JP2008503716A (enExample)
CN (1) CN1976725B (enExample)
AU (1) AU2005256961B2 (enExample)
BR (1) BRPI0512281A (enExample)
CA (1) CA2571565C (enExample)
ES (2) ES2443465T3 (enExample)
GB (1) GB0413868D0 (enExample)
MX (2) MXPA06015188A (enExample)
NZ (1) NZ552449A (enExample)
RU (1) RU2422156C2 (enExample)
WO (1) WO2006000920A2 (enExample)

Cited By (8)

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JP2011522252A (ja) * 2008-05-30 2011-07-28 インターベツト・インターナシヨナル・ベー・ベー ワクチンの効力および安定性を監視するための分析方法
JP2013514538A (ja) * 2009-12-15 2013-04-25 ウオーターズ・テクノロジーズ・コーポレイシヨン サイズ排除クロマトグラフィーを行うための装置および方法
JP2017014217A (ja) * 2010-05-26 2017-01-19 セレクタ バイオサイエンシーズ インコーポレーテッドＳｅｌｅｃｔａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． 合成ナノキャリア混合ワクチン
US10092893B2 (en) 2010-07-26 2018-10-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
KR20200097239A (ko) * 2017-09-06 2020-08-18 상하이 그린벨리 파머수티컬 주식회사 중량평균 분자량 및 산성 당의 가용성 염의 함량 측정방법
JP2021089234A (ja) * 2019-12-05 2021-06-10 株式会社島津製作所 検出器の出力を補正する方法、および多角度光散乱検出器
US11291974B2 (en) 2009-06-01 2022-04-05 Waters Technologies Corporation Hybrid inorganic/organic materials having novel surface modification; process for the preparation of inorganic/organic hybrid materials; and use of said particles for chromatographic separations
US12623205B2 (en) 2010-07-26 2026-05-12 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution

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GB0413868D0 (en) * 2004-06-21 2004-07-21 Chiron Srl Dimensional anlaysis of saccharide conjugates
LT2351578T (lt) * 2005-06-27 2017-04-10 Glaxosmithkline Biologicals S.A. Vakcinų gavimo būdas
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
US8195405B2 (en) * 2009-06-30 2012-06-05 Wyatt Technology Corporation Method for characterizing reversible association of macromolecules at high concentration
PL2493498T3 (pl) * 2009-10-30 2017-08-31 Glaxosmithkline Biologicals Sa Oczyszczanie sacharydów otoczkowych staphylococcus aureus typu 5 i typu 8
RU2580620C2 (ru) 2010-08-23 2016-04-10 ВАЙЕТ ЭлЭлСи СТАБИЛЬНЫЕ КОМПОЗИЦИИ АНТИГЕНОВ Neisseria meningitidis rLP2086
WO2012032489A1 (en) 2010-09-10 2012-03-15 Wyeth Llc Non-lipidated variants of neisseria meningitidis orf2086 antigens
CA2865745C (en) 2012-03-09 2018-01-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
US10481164B2 (en) 2012-03-26 2019-11-19 Amgen Inc. Method for using light scattering in real time to directly monitor and control impurity removal in purification processes
US9802987B2 (en) 2013-03-08 2017-10-31 Pfizer Inc. Immunogenic fusion polypeptides
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
AU2016221318B2 (en) 2015-02-19 2020-06-25 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
RS65362B1 (sr) 2016-09-02 2024-04-30 Sanofi Pasteur Inc Vakcina protiv neisseria meningitidis
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MX2019007910A (es) 2016-12-30 2019-12-05 Sutrovax Inc Conjugados de polipeptido-antigeno con aminoacidos no naturales.
US10183070B2 (en) 2017-01-31 2019-01-22 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CN109459504B (zh) * 2017-09-06 2022-05-27 绿谷(上海)医药科技有限公司 一种测定聚古罗糖醛酸硫酸酯盐重均分子量和含量的方法
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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011522252A (ja) * 2008-05-30 2011-07-28 インターベツト・インターナシヨナル・ベー・ベー ワクチンの効力および安定性を監視するための分析方法
US11291974B2 (en) 2009-06-01 2022-04-05 Waters Technologies Corporation Hybrid inorganic/organic materials having novel surface modification; process for the preparation of inorganic/organic hybrid materials; and use of said particles for chromatographic separations
JP2018021929A (ja) * 2009-12-15 2018-02-08 ウオーターズ・テクノロジーズ・コーポレイシヨン サイズ排除クロマトグラフィーを行うための装置および方法
JP2013514538A (ja) * 2009-12-15 2013-04-25 ウオーターズ・テクノロジーズ・コーポレイシヨン サイズ排除クロマトグラフィーを行うための装置および方法
JP2017014217A (ja) * 2010-05-26 2017-01-19 セレクタ バイオサイエンシーズ インコーポレーテッドＳｅｌｅｃｔａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． 合成ナノキャリア混合ワクチン
JP2018052940A (ja) * 2010-05-26 2018-04-05 セレクタ バイオサイエンシーズ インコーポレーテッドＳｅｌｅｃｔａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． 多価合成ナノキャリアワクチン
US10092893B2 (en) 2010-07-26 2018-10-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
US11478775B2 (en) 2010-07-26 2022-10-25 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution
US12427502B2 (en) 2010-07-26 2025-09-30 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
US12623205B2 (en) 2010-07-26 2026-05-12 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution
KR20200097239A (ko) * 2017-09-06 2020-08-18 상하이 그린벨리 파머수티컬 주식회사 중량평균 분자량 및 산성 당의 가용성 염의 함량 측정방법
KR102338499B1 (ko) 2017-09-06 2021-12-14 상하이 그린벨리 파머수티컬 주식회사 중량평균 분자량 및 산성 당의 가용성 염의 함량 측정방법
US11366086B2 (en) 2017-09-06 2022-06-21 Shanghai Green Valley Pharmaceutical Co., Ltd. Method for determining weight-average molecular weight and content of soluble salt of acidic carbohydrates
JP2021089234A (ja) * 2019-12-05 2021-06-10 株式会社島津製作所 検出器の出力を補正する方法、および多角度光散乱検出器
JP7409055B2 (ja) 2019-12-05 2024-01-09 株式会社島津製作所 検出器の出力を補正する方法、および多角度光散乱検出器

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WO2006000920A3 (en) 2006-03-30
CA2571565A1 (en) 2006-01-05
EP1778291A2 (en) 2007-05-02
GB0413868D0 (en) 2004-07-21
ES2443465T3 (es) 2014-02-19
JP6661568B2 (ja) 2020-03-11
WO2006000920A2 (en) 2006-01-05
JP2014111654A (ja) 2014-06-19
MXPA06015188A (es) 2007-03-27
CA2571565C (en) 2014-08-12
RU2422156C2 (ru) 2011-06-27
AU2005256961B2 (en) 2011-06-23
US8163296B2 (en) 2012-04-24
MX344621B (es) 2017-01-03
AU2005256961A1 (en) 2006-01-05
JP6218327B2 (ja) 2017-10-25
US20120207781A1 (en) 2012-08-16
JP2011246490A (ja) 2011-12-08
CN1976725B (zh) 2012-08-29
BRPI0512281A (pt) 2008-02-26
ES2688796T3 (es) 2018-11-07
JP2015180707A (ja) 2015-10-15
NZ552449A (en) 2010-05-28
EP1778291B1 (en) 2013-10-30
US20080248059A1 (en) 2008-10-09
EP2374473B1 (en) 2018-07-18
CN1976725A (zh) 2007-06-06
EP2374473A1 (en) 2011-10-12
RU2007102016A (ru) 2008-07-27
JP2017134084A (ja) 2017-08-03

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