JP2008503716A5 - - Google Patents
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- JP2008503716A5 JP2008503716A5 JP2007516078A JP2007516078A JP2008503716A5 JP 2008503716 A5 JP2008503716 A5 JP 2008503716A5 JP 2007516078 A JP2007516078 A JP 2007516078A JP 2007516078 A JP2007516078 A JP 2007516078A JP 2008503716 A5 JP2008503716 A5 JP 2008503716A5
- Authority
- JP
- Japan
- Prior art keywords
- serotype
- conjugate
- sugar
- batch
- molecular weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001720 carbohydrates Chemical class 0.000 claims 12
- 241000588650 Neisseria meningitidis Species 0.000 claims 8
- 229960005486 vaccine Drugs 0.000 claims 6
- 229920000642 polymer Polymers 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0413868.1A GB0413868D0 (en) | 2004-06-21 | 2004-06-21 | Dimensional anlaysis of saccharide conjugates |
| PCT/IB2005/002532 WO2006000920A2 (en) | 2004-06-21 | 2005-06-21 | Dimensional analysis of saccharide conjugates with gpc & sec-mals |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011192126A Division JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008503716A JP2008503716A (ja) | 2008-02-07 |
| JP2008503716A5 true JP2008503716A5 (enExample) | 2008-07-17 |
Family
ID=32750313
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516078A Withdrawn JP2008503716A (ja) | 2004-06-21 | 2005-06-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2011192126A Withdrawn JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2014047555A Expired - Lifetime JP6218327B2 (ja) | 2004-06-21 | 2014-03-11 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2015143718A Pending JP2015180707A (ja) | 2004-06-21 | 2015-07-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2017084454A Expired - Lifetime JP6661568B2 (ja) | 2004-06-21 | 2017-04-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011192126A Withdrawn JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2014047555A Expired - Lifetime JP6218327B2 (ja) | 2004-06-21 | 2014-03-11 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2015143718A Pending JP2015180707A (ja) | 2004-06-21 | 2015-07-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2017084454A Expired - Lifetime JP6661568B2 (ja) | 2004-06-21 | 2017-04-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8163296B2 (enExample) |
| EP (2) | EP2374473B1 (enExample) |
| JP (5) | JP2008503716A (enExample) |
| CN (1) | CN1976725B (enExample) |
| AU (1) | AU2005256961B2 (enExample) |
| BR (1) | BRPI0512281A (enExample) |
| CA (1) | CA2571565C (enExample) |
| ES (2) | ES2688796T3 (enExample) |
| GB (1) | GB0413868D0 (enExample) |
| MX (2) | MXPA06015188A (enExample) |
| NZ (1) | NZ552449A (enExample) |
| RU (1) | RU2422156C2 (enExample) |
| WO (1) | WO2006000920A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0413868D0 (en) * | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
| PL2878307T3 (pl) | 2005-06-27 | 2020-01-31 | Glaxosmithkline Biologicals S.A. | Kompozycja immunogenna |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| TW201009337A (en) * | 2008-05-30 | 2010-03-01 | Intervet Int Bv | Analytical method to monitor vaccine potency and stability |
| EP2437882A4 (en) | 2009-06-01 | 2016-11-23 | Waters Technologies Corp | HYBRID MATERIAL FOR CHROMATOGRAPHY SEPARATIONS |
| US8195405B2 (en) * | 2009-06-30 | 2012-06-05 | Wyatt Technology Corporation | Method for characterizing reversible association of macromolecules at high concentration |
| SMT201700275T1 (it) | 2009-10-30 | 2017-07-18 | Glaxosmithkline Biologicals Sa | Purificazione di saccaridi capsulari di staphylococcus aureus tipo 5 e tipo 8 |
| EP4023330A1 (en) * | 2009-12-15 | 2022-07-06 | Waters Technologies Corporation | Device and methods for performing size exclusion chromatography |
| US20110293700A1 (en) * | 2010-05-26 | 2011-12-01 | Selecta Biosciences, Inc. | Nanocarrier compositions with uncoupled adjuvant |
| WO2012018598A1 (en) | 2010-07-26 | 2012-02-09 | Waters Technologies Corporation | Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations |
| PT3246044T (pt) | 2010-08-23 | 2021-02-15 | Wyeth Llc | Formulações estáveis de antigénios de rlp2086 de neisseria meningitidis |
| AU2011300409B2 (en) | 2010-09-10 | 2015-03-26 | Wyeth Llc | Non-lipidated variants of Neisseria meningitidis ORF2086 antigens |
| US8986710B2 (en) | 2012-03-09 | 2015-03-24 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| US10481164B2 (en) | 2012-03-26 | 2019-11-19 | Amgen Inc. | Method for using light scattering in real time to directly monitor and control impurity removal in purification processes |
| WO2014136064A2 (en) | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Immunogenic fusion polypeptides |
| MX369534B (es) | 2013-09-08 | 2019-11-11 | Pfizer | Composiciones de neisseria meningitidis y sus metodos. |
| RU2723045C2 (ru) | 2015-02-19 | 2020-06-08 | Пфайзер Инк. | Композиции neisseria meningitidis и способы их получения |
| KR20190044663A (ko) | 2016-09-02 | 2019-04-30 | 사노피 파스퇴르 인크 | 네이세리아 메닌기티디스 백신 |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| KR20190103256A (ko) | 2016-12-30 | 2019-09-04 | 수트로박스, 인코포레이티드 | 비자연 아미노산을 갖는 폴리펩타이드-항원 접합체 |
| SG10202111092UA (en) | 2017-01-31 | 2021-11-29 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| CN109459523B (zh) * | 2017-09-06 | 2022-11-08 | 上海绿谷制药有限公司 | 一种测定酸性糖可溶性盐重均分子量和含量的方法 |
| CN109459504B (zh) * | 2017-09-06 | 2022-05-27 | 绿谷(上海)医药科技有限公司 | 一种测定聚古罗糖醛酸硫酸酯盐重均分子量和含量的方法 |
| CA3155669A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| JP7409055B2 (ja) * | 2019-12-05 | 2024-01-09 | 株式会社島津製作所 | 検出器の出力を補正する方法、および多角度光散乱検出器 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4057685A (en) | 1972-02-02 | 1977-11-08 | Abbott Laboratories | Chemically modified endotoxin immunizing agent |
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4459286A (en) | 1983-01-31 | 1984-07-10 | Merck & Co., Inc. | Coupled H. influenzae type B vaccine |
| US4663160A (en) | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
| US4761283A (en) | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| US4808700A (en) | 1984-07-09 | 1989-02-28 | Praxis Biologics, Inc. | Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers |
| RU2023448C1 (ru) | 1987-07-30 | 1994-11-30 | Сентро Насьональ Де Биопрепарадос | Способ получения вакцины против различных патогенных серотипов менингита нейссера группы в |
| NL8802046A (nl) | 1988-08-18 | 1990-03-16 | Gen Electric | Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen. |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| EP0378881B1 (en) | 1989-01-17 | 1993-06-09 | ENIRICERCHE S.p.A. | Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines |
| EP0482068A1 (en) | 1989-07-14 | 1992-04-29 | American Cyanamid Company | Cytokine and hormone carriers for conjugate vaccines |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| EP0471177B1 (en) | 1990-08-13 | 1995-10-04 | American Cyanamid Company | Filamentous hemagglutinin of bordetella pertussis as a carrier molecule for conjugate vaccines |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| WO1996040242A1 (en) | 1995-06-07 | 1996-12-19 | Smithkline Beecham Biologicals S.A. | Vaccine comprising a polysaccharide antigen-carrier protein conjugate and free carrier protein |
| US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| US7018637B2 (en) | 1998-02-23 | 2006-03-28 | Aventis Pasteur, Inc | Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines |
| CA2340692A1 (en) | 1998-08-19 | 2000-03-02 | North American Vaccine, Inc. | Immunogenic .beta.-propionamido-linked polysaccharide protein conjugate useful as a vaccine produced using an n-acryloylated polysaccharide |
| EP1162999B1 (en) | 1999-03-19 | 2006-11-29 | Glaxosmithkline Biologicals S.A. | Vaccine against Streptococcus pneumoniae |
| JP2002541808A (ja) | 1999-04-09 | 2002-12-10 | テクラブ， インコーポレイテッド | ポリサッカリド結合体ワクチンのための組換えトキシンａタンパク質キャリア |
| EP2275129A3 (en) | 2000-01-17 | 2013-11-06 | Novartis Vaccines and Diagnostics S.r.l. | Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins |
| GB0007432D0 (en) | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| ES2519440T3 (es) | 2000-07-27 | 2014-11-07 | Children's Hospital & Research Center At Oakland | Vacunas para la protección de amplio espectro contra enfermedades causadas por Neisseria meningitidis |
| GB0103170D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| JP2005504718A (ja) * | 2001-01-23 | 2005-02-17 | アヴェンティス パストゥール | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| AU2002309706A1 (en) | 2001-05-11 | 2002-11-25 | Aventis Pasteur, Inc. | Novel meningitis conjugate vaccine |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| DE60335477D1 (de) * | 2002-10-11 | 2011-02-03 | Novartis Vaccines & Diagnostic | Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien |
| PT2172213E (pt) | 2003-01-30 | 2013-06-03 | Novartis Ag | Vacinas injetáveis contra múltiplos serogrupos meningocócicos |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| ATE506963T1 (de) * | 2003-10-02 | 2011-05-15 | Novartis Vaccines & Diagnostic | Kombinationsimpfstoffe gegen meningitis |
| GB0408978D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Meningococcal fermentation for preparing conjugate vaccines |
| GB0413868D0 (en) * | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
-
2004
- 2004-06-21 GB GBGB0413868.1A patent/GB0413868D0/en not_active Ceased
-
2005
- 2005-06-21 CN CN2005800204436A patent/CN1976725B/zh not_active Expired - Lifetime
- 2005-06-21 ES ES11163751.8T patent/ES2688796T3/es not_active Expired - Lifetime
- 2005-06-21 JP JP2007516078A patent/JP2008503716A/ja not_active Withdrawn
- 2005-06-21 EP EP11163751.8A patent/EP2374473B1/en not_active Expired - Lifetime
- 2005-06-21 CA CA2571565A patent/CA2571565C/en not_active Expired - Lifetime
- 2005-06-21 AU AU2005256961A patent/AU2005256961B2/en not_active Expired
- 2005-06-21 EP EP05770612.9A patent/EP1778291B1/en not_active Expired - Lifetime
- 2005-06-21 BR BRPI0512281-3A patent/BRPI0512281A/pt not_active Application Discontinuation
- 2005-06-21 ES ES05770612.9T patent/ES2443465T3/es not_active Expired - Lifetime
- 2005-06-21 WO PCT/IB2005/002532 patent/WO2006000920A2/en not_active Ceased
- 2005-06-21 MX MXPA06015188A patent/MXPA06015188A/es active IP Right Grant
- 2005-06-21 US US11/630,545 patent/US8163296B2/en active Active
- 2005-06-21 NZ NZ552449A patent/NZ552449A/en not_active IP Right Cessation
- 2005-06-21 RU RU2007102016/15A patent/RU2422156C2/ru active IP Right Revival
-
2006
- 2006-12-20 MX MX2011011568A patent/MX344621B/es unknown
-
2011
- 2011-09-02 JP JP2011192126A patent/JP2011246490A/ja not_active Withdrawn
-
2012
- 2012-04-24 US US13/454,658 patent/US20120207781A1/en not_active Abandoned
-
2014
- 2014-03-11 JP JP2014047555A patent/JP6218327B2/ja not_active Expired - Lifetime
-
2015
- 2015-07-21 JP JP2015143718A patent/JP2015180707A/ja active Pending
-
2017
- 2017-04-21 JP JP2017084454A patent/JP6661568B2/ja not_active Expired - Lifetime