JP2008503716A5 - - Google Patents
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- Publication number
- JP2008503716A5 JP2008503716A5 JP2007516078A JP2007516078A JP2008503716A5 JP 2008503716 A5 JP2008503716 A5 JP 2008503716A5 JP 2007516078 A JP2007516078 A JP 2007516078A JP 2007516078 A JP2007516078 A JP 2007516078A JP 2008503716 A5 JP2008503716 A5 JP 2008503716A5
- Authority
- JP
- Japan
- Prior art keywords
- serotype
- conjugate
- sugar
- batch
- molecular weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001720 carbohydrates Chemical class 0.000 claims 12
- 241000588650 Neisseria meningitidis Species 0.000 claims 8
- 229960005486 vaccine Drugs 0.000 claims 6
- 229920000642 polymer Polymers 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0413868.1A GB0413868D0 (en) | 2004-06-21 | 2004-06-21 | Dimensional anlaysis of saccharide conjugates |
| PCT/IB2005/002532 WO2006000920A2 (en) | 2004-06-21 | 2005-06-21 | Dimensional analysis of saccharide conjugates with gpc & sec-mals |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011192126A Division JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008503716A JP2008503716A (ja) | 2008-02-07 |
| JP2008503716A5 true JP2008503716A5 (enExample) | 2008-07-17 |
Family
ID=32750313
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516078A Withdrawn JP2008503716A (ja) | 2004-06-21 | 2005-06-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2011192126A Withdrawn JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2014047555A Expired - Lifetime JP6218327B2 (ja) | 2004-06-21 | 2014-03-11 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2015143718A Pending JP2015180707A (ja) | 2004-06-21 | 2015-07-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2017084454A Expired - Lifetime JP6661568B2 (ja) | 2004-06-21 | 2017-04-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011192126A Withdrawn JP2011246490A (ja) | 2004-06-21 | 2011-09-02 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2014047555A Expired - Lifetime JP6218327B2 (ja) | 2004-06-21 | 2014-03-11 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2015143718A Pending JP2015180707A (ja) | 2004-06-21 | 2015-07-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
| JP2017084454A Expired - Lifetime JP6661568B2 (ja) | 2004-06-21 | 2017-04-21 | Ｇｐｃおよびｓｅｃ−ｍａｌｓによる結合体化糖の寸法分析 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8163296B2 (enExample) |
| EP (2) | EP1778291B1 (enExample) |
| JP (5) | JP2008503716A (enExample) |
| CN (1) | CN1976725B (enExample) |
| AU (1) | AU2005256961B2 (enExample) |
| BR (1) | BRPI0512281A (enExample) |
| CA (1) | CA2571565C (enExample) |
| ES (2) | ES2443465T3 (enExample) |
| GB (1) | GB0413868D0 (enExample) |
| MX (2) | MXPA06015188A (enExample) |
| NZ (1) | NZ552449A (enExample) |
| RU (1) | RU2422156C2 (enExample) |
| WO (1) | WO2006000920A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0413868D0 (en) * | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
| LT2351578T (lt) * | 2005-06-27 | 2017-04-10 | Glaxosmithkline Biologicals S.A. | Vakcinų gavimo būdas |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| TW201009337A (en) | 2008-05-30 | 2010-03-01 | Intervet Int Bv | Analytical method to monitor vaccine potency and stability |
| WO2010141426A1 (en) | 2009-06-01 | 2010-12-09 | Waters Technologies Corporation | Hybrid material for chromatographic separations |
| US8195405B2 (en) * | 2009-06-30 | 2012-06-05 | Wyatt Technology Corporation | Method for characterizing reversible association of macromolecules at high concentration |
| PL2493498T3 (pl) * | 2009-10-30 | 2017-08-31 | Glaxosmithkline Biologicals Sa | Oczyszczanie sacharydów otoczkowych staphylococcus aureus typu 5 i typu 8 |
| EP4023330A1 (en) * | 2009-12-15 | 2022-07-06 | Waters Technologies Corporation | Device and methods for performing size exclusion chromatography |
| CN102905728B (zh) * | 2010-05-26 | 2015-11-25 | 西莱克塔生物科技公司 | 具有不偶合的佐剂的纳米载体组合物 |
| US12623205B2 (en) | 2010-07-26 | 2026-05-12 | Waters Technologies Corporation | Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution |
| JP6199184B2 (ja) | 2010-07-26 | 2017-09-20 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 粒度分布の狭い実質的に非多孔質のコアを含む表面多孔質材料、その製造方法及びクロマトグラフィー分離用としてのその使用 |
| RU2580620C2 (ru) | 2010-08-23 | 2016-04-10 | ВАЙЕТ ЭлЭлСи | СТАБИЛЬНЫЕ КОМПОЗИЦИИ АНТИГЕНОВ Neisseria meningitidis rLP2086 |
| WO2012032489A1 (en) | 2010-09-10 | 2012-03-15 | Wyeth Llc | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
| CA2865745C (en) | 2012-03-09 | 2018-01-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| US10481164B2 (en) | 2012-03-26 | 2019-11-19 | Amgen Inc. | Method for using light scattering in real time to directly monitor and control impurity removal in purification processes |
| US9802987B2 (en) | 2013-03-08 | 2017-10-31 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| RS65362B1 (sr) | 2016-09-02 | 2024-04-30 | Sanofi Pasteur Inc | Vakcina protiv neisseria meningitidis |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| MX2019007910A (es) | 2016-12-30 | 2019-12-05 | Sutrovax Inc | Conjugados de polipeptido-antigeno con aminoacidos no naturales. |
| US10183070B2 (en) | 2017-01-31 | 2019-01-22 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| CN109459523B (zh) * | 2017-09-06 | 2022-11-08 | 上海绿谷制药有限公司 | 一种测定酸性糖可溶性盐重均分子量和含量的方法 |
| CN109459504B (zh) * | 2017-09-06 | 2022-05-27 | 绿谷(上海)医药科技有限公司 | 一种测定聚古罗糖醛酸硫酸酯盐重均分子量和含量的方法 |
| EP4034157A1 (en) | 2019-09-27 | 2022-08-03 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| JP7409055B2 (ja) * | 2019-12-05 | 2024-01-09 | 株式会社島津製作所 | 検出器の出力を補正する方法、および多角度光散乱検出器 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4057685A (en) | 1972-02-02 | 1977-11-08 | Abbott Laboratories | Chemically modified endotoxin immunizing agent |
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4459286A (en) | 1983-01-31 | 1984-07-10 | Merck & Co., Inc. | Coupled H. influenzae type B vaccine |
| US4663160A (en) | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
| US4761283A (en) | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| US4808700A (en) | 1984-07-09 | 1989-02-28 | Praxis Biologics, Inc. | Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers |
| JPH01125328A (ja) | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | 髄膜炎菌ワクチン |
| NL8802046A (nl) | 1988-08-18 | 1990-03-16 | Gen Electric | Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen. |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| DE68907045T2 (de) | 1989-01-17 | 1993-12-02 | Eniricerche Spa | Synthetische Peptide und deren Verwendung als allgemeine Träger für die Herstellung von immunogenischen Konjugaten, die für die Entwicklung von synthetischen Impfstoffen geeignet sind. |
| JPH04506662A (ja) | 1989-07-14 | 1992-11-19 | アメリカン・サイアナミド・カンパニー | 接合体ワクチンのためのサイトカイニンおよびホルモンのキヤリヤー |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| DE69113564T2 (de) | 1990-08-13 | 1996-05-30 | American Cyanamid Co | Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff. |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| NZ311000A (en) | 1995-06-07 | 1999-04-29 | Smithkline Beecham Biolog | Vaccine comprising a polysaccharide antigen-carrier protein conjugate and a free carrier protein |
| US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| US7018637B2 (en) | 1998-02-23 | 2006-03-28 | Aventis Pasteur, Inc | Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines |
| CN1263510C (zh) | 1998-08-19 | 2006-07-12 | 巴克斯特健康护理股份有限公司 | 多糖－蛋白质缀合物或寡糖－蛋白质缀合物、其制备方法及其应用 |
| JP2002539273A (ja) | 1999-03-19 | 2002-11-19 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | ワクチン |
| CA2365914A1 (en) | 1999-04-09 | 2000-10-19 | Techlab, Inc. | Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines |
| CA2871789C (en) | 2000-01-17 | 2017-04-04 | Novartis Vaccines And Diagnostics S.R.L. | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins |
| GB0007432D0 (en) | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| KR20030024811A (ko) | 2000-07-27 | 2003-03-26 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 나이세리아 메닌지티디스에 의하여 유발되는 질병에 대한광범위하게 유효한 보호를 위한 백신 |
| GB0103170D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| PT2332581E (pt) * | 2001-01-23 | 2015-10-16 | Sanofi Pasteur Inc | Vacina meningocócica tri- ou tetravalente de conjugados de polissacárido e crm-197 |
| US20030035806A1 (en) * | 2001-05-11 | 2003-02-20 | D'ambra Anello J. | Novel meningitis conjugate vaccine |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| CN1809380B (zh) | 2002-10-11 | 2010-05-12 | 启龙有限公司 | 广泛防御高毒性脑膜炎球菌谱系的多肽-疫苗 |
| ES2461350T3 (es) | 2003-01-30 | 2014-05-19 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| NZ546430A (en) * | 2003-10-02 | 2009-04-30 | Novartis Vaccines & Diagnostic | Liquid vaccines for multiple meningococcal serogroups |
| GB0408978D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Meningococcal fermentation for preparing conjugate vaccines |
| GB0413868D0 (en) * | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
-
2004
- 2004-06-21 GB GBGB0413868.1A patent/GB0413868D0/en not_active Ceased
-
2005
- 2005-06-21 CN CN2005800204436A patent/CN1976725B/zh not_active Expired - Lifetime
- 2005-06-21 AU AU2005256961A patent/AU2005256961B2/en not_active Expired
- 2005-06-21 MX MXPA06015188A patent/MXPA06015188A/es active IP Right Grant
- 2005-06-21 EP EP05770612.9A patent/EP1778291B1/en not_active Expired - Lifetime
- 2005-06-21 RU RU2007102016/15A patent/RU2422156C2/ru active IP Right Revival
- 2005-06-21 NZ NZ552449A patent/NZ552449A/en not_active IP Right Cessation
- 2005-06-21 ES ES05770612.9T patent/ES2443465T3/es not_active Expired - Lifetime
- 2005-06-21 US US11/630,545 patent/US8163296B2/en active Active
- 2005-06-21 EP EP11163751.8A patent/EP2374473B1/en not_active Expired - Lifetime
- 2005-06-21 WO PCT/IB2005/002532 patent/WO2006000920A2/en not_active Ceased
- 2005-06-21 ES ES11163751.8T patent/ES2688796T3/es not_active Expired - Lifetime
- 2005-06-21 CA CA2571565A patent/CA2571565C/en not_active Expired - Lifetime
- 2005-06-21 JP JP2007516078A patent/JP2008503716A/ja not_active Withdrawn
- 2005-06-21 BR BRPI0512281-3A patent/BRPI0512281A/pt not_active Application Discontinuation
-
2006
- 2006-12-20 MX MX2011011568A patent/MX344621B/es unknown
-
2011
- 2011-09-02 JP JP2011192126A patent/JP2011246490A/ja not_active Withdrawn
-
2012
- 2012-04-24 US US13/454,658 patent/US20120207781A1/en not_active Abandoned
-
2014
- 2014-03-11 JP JP2014047555A patent/JP6218327B2/ja not_active Expired - Lifetime
-
2015
- 2015-07-21 JP JP2015143718A patent/JP2015180707A/ja active Pending
-
2017
- 2017-04-21 JP JP2017084454A patent/JP6661568B2/ja not_active Expired - Lifetime
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