RU2422156C2 - Композиции конъюгатов сахаридов - Google Patents

Композиции конъюгатов сахаридов Download PDF

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Publication number
RU2422156C2
RU2422156C2 RU2007102016/15A RU2007102016A RU2422156C2 RU 2422156 C2 RU2422156 C2 RU 2422156C2 RU 2007102016/15 A RU2007102016/15 A RU 2007102016/15A RU 2007102016 A RU2007102016 A RU 2007102016A RU 2422156 C2 RU2422156 C2 RU 2422156C2
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RU
Russia
Prior art keywords
conjugate
serogroup
saccharide
molar mass
conjugates
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RU2007102016/15A
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English (en)
Russian (ru)
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RU2007102016A (ru
Inventor
Джорджо КАПАННОЛИ (IT)
Джорджо КАПАННОЛИ
Валериа КАРИНЧИ (IT)
Валериа КАРИНЧИ
Сандро Д'АШЕНЦИ (IT)
Сандро Д'АШЕНЦИ
Клаудиа МАГАНЬОЛИ (IT)
Клаудиа МАГАНЬОЛИ
Original Assignee
Новартис Вэксинс Энд Диагностикс С.Р.Л.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of RU2007102016A publication Critical patent/RU2007102016A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Spectrometry And Color Measurement (AREA)
RU2007102016/15A 2004-06-21 2005-06-21 Композиции конъюгатов сахаридов RU2422156C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0413868.1 2004-06-21
GBGB0413868.1A GB0413868D0 (en) 2004-06-21 2004-06-21 Dimensional anlaysis of saccharide conjugates

Publications (2)

Publication Number Publication Date
RU2007102016A RU2007102016A (ru) 2008-07-27
RU2422156C2 true RU2422156C2 (ru) 2011-06-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007102016/15A RU2422156C2 (ru) 2004-06-21 2005-06-21 Композиции конъюгатов сахаридов

Country Status (13)

Country Link
US (2) US8163296B2 (enExample)
EP (2) EP2374473B1 (enExample)
JP (5) JP2008503716A (enExample)
CN (1) CN1976725B (enExample)
AU (1) AU2005256961B2 (enExample)
BR (1) BRPI0512281A (enExample)
CA (1) CA2571565C (enExample)
ES (2) ES2688796T3 (enExample)
GB (1) GB0413868D0 (enExample)
MX (2) MXPA06015188A (enExample)
NZ (1) NZ552449A (enExample)
RU (1) RU2422156C2 (enExample)
WO (1) WO2006000920A2 (enExample)

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KR20190044663A (ko) 2016-09-02 2019-04-30 사노피 파스퇴르 인크 네이세리아 메닌기티디스 백신
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SG10202111092UA (en) 2017-01-31 2021-11-29 Pfizer Neisseria meningitidis compositions and methods thereof
CN109459523B (zh) * 2017-09-06 2022-11-08 上海绿谷制药有限公司 一种测定酸性糖可溶性盐重均分子量和含量的方法
CN109459504B (zh) * 2017-09-06 2022-05-27 绿谷(上海)医药科技有限公司 一种测定聚古罗糖醛酸硫酸酯盐重均分子量和含量的方法
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JP7409055B2 (ja) * 2019-12-05 2024-01-09 株式会社島津製作所 検出器の出力を補正する方法、および多角度光散乱検出器

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Also Published As

Publication number Publication date
WO2006000920A2 (en) 2006-01-05
JP2008503716A (ja) 2008-02-07
EP2374473A1 (en) 2011-10-12
US8163296B2 (en) 2012-04-24
EP1778291A2 (en) 2007-05-02
JP6218327B2 (ja) 2017-10-25
NZ552449A (en) 2010-05-28
JP6661568B2 (ja) 2020-03-11
US20120207781A1 (en) 2012-08-16
US20080248059A1 (en) 2008-10-09
GB0413868D0 (en) 2004-07-21
WO2006000920A3 (en) 2006-03-30
AU2005256961B2 (en) 2011-06-23
ES2688796T3 (es) 2018-11-07
CN1976725A (zh) 2007-06-06
RU2007102016A (ru) 2008-07-27
MX344621B (es) 2017-01-03
MXPA06015188A (es) 2007-03-27
CA2571565C (en) 2014-08-12
AU2005256961A1 (en) 2006-01-05
ES2443465T3 (es) 2014-02-19
EP1778291B1 (en) 2013-10-30
JP2011246490A (ja) 2011-12-08
BRPI0512281A (pt) 2008-02-26
JP2017134084A (ja) 2017-08-03
JP2015180707A (ja) 2015-10-15
CN1976725B (zh) 2012-08-29
CA2571565A1 (en) 2006-01-05
EP2374473B1 (en) 2018-07-18
JP2014111654A (ja) 2014-06-19

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20110622

NF4A Reinstatement of patent

Effective date: 20130410