JP2008502332A5 - - Google Patents

Download PDF

Info

Publication number
JP2008502332A5
JP2008502332A5 JP2007515787A JP2007515787A JP2008502332A5 JP 2008502332 A5 JP2008502332 A5 JP 2008502332A5 JP 2007515787 A JP2007515787 A JP 2007515787A JP 2007515787 A JP2007515787 A JP 2007515787A JP 2008502332 A5 JP2008502332 A5 JP 2008502332A5
Authority
JP
Japan
Prior art keywords
nucleic acid
sample
methylated
acid fragments
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007515787A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008502332A (ja
Filing date
Publication date
Priority claimed from GBGB0413688.3A external-priority patent/GB0413688D0/en
Application filed filed Critical
Publication of JP2008502332A publication Critical patent/JP2008502332A/ja
Publication of JP2008502332A5 publication Critical patent/JP2008502332A5/ja
Pending legal-status Critical Current

Links

JP2007515787A 2004-06-18 2005-03-03 メチル化核酸の分析 Pending JP2008502332A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0413688.3A GB0413688D0 (en) 2004-06-18 2004-06-18 Analysis of methylated nucleic acid
PCT/EP2005/002251 WO2005123942A2 (en) 2004-06-18 2005-03-03 Analysis of methylated nucleic acid

Publications (2)

Publication Number Publication Date
JP2008502332A JP2008502332A (ja) 2008-01-31
JP2008502332A5 true JP2008502332A5 (enExample) 2008-04-17

Family

ID=32750180

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007515787A Pending JP2008502332A (ja) 2004-06-18 2005-03-03 メチル化核酸の分析

Country Status (8)

Country Link
US (2) US20090270482A1 (enExample)
EP (1) EP1761639B1 (enExample)
JP (1) JP2008502332A (enExample)
AU (2) AU2005254616A1 (enExample)
CA (1) CA2568575A1 (enExample)
ES (1) ES2401110T3 (enExample)
GB (1) GB0413688D0 (enExample)
WO (1) WO2005123942A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005034628B4 (de) * 2005-07-19 2007-08-23 Epigenomics Ag Verfahren zur Untersuchung von Cytosin-Methylierungen in DNA
EP1862555A1 (en) * 2006-05-29 2007-12-05 Klinikum der Universität Regensburg Means and methods for diagnosing cancer or a corresponding predisposition
WO2007149269A2 (en) * 2006-06-12 2007-12-27 Oncomethylome Sciences S.A. Methylation markers for early detection and prognosis of colon cancers
EP2644713B1 (en) * 2007-10-23 2018-07-04 Clinical Genomics Pty Ltd A method of diagnosing neoplasms - II
JP2009247260A (ja) * 2008-04-04 2009-10-29 Sumitomo Chemical Co Ltd Ｄｎａメチル化測定方法
KR101636596B1 (ko) * 2009-04-17 2016-07-11 내셔널 디펜스 메디컬 센터 검사 표지로서 표적 유전자의 메틸화율을 검출하는 방법
DK2529032T3 (en) 2010-01-26 2017-05-01 Nipd Genetics Ltd METHODS AND COMPOSITIONS FOR NON-INVASIVE PRE-NATIONAL DIAGNOSTICATION OF Fetal ANEUPLOIDITIES
US8278049B2 (en) 2010-04-26 2012-10-02 Ann & Robert H. Lurie Children's Hospital of Chicago Selective enrichment of CpG islands
US20120004132A1 (en) * 2010-07-02 2012-01-05 Affymetrix, Inc. Detection of Nucleic Acids and Proteins
JP5916058B2 (ja) * 2011-08-26 2016-05-11 国立大学法人東北大学 細胞ストレス状態のバイオマーカー
WO2013123481A1 (en) 2012-02-16 2013-08-22 Cornell University Methods and kit for characterizing the modified base status of a transcriptome
EP3037535A4 (en) * 2013-08-21 2017-04-05 Fujirebio Inc. Method for measuring modified nucleic-acid base using absorbent polynucleotide and kit therefor
PT3666902T (pt) 2015-05-22 2024-09-19 Medicover Public Co Ltd Análise paralela multiplexada de regiões genómicas alvo para testes pré-natais não invasivos
KR101735415B1 (ko) * 2015-07-31 2017-05-16 한국과학기술연구원 헥산알 노출 특이적 메틸화 마커 유전자 및 이를 이용한 확인 방법
JP6900325B2 (ja) * 2016-01-27 2021-07-07 住友化学株式会社 センサーチップ及びセンシングシステム
CA3014911A1 (en) * 2016-02-23 2017-08-31 Dovetail Genomics, Llc Generation of phased read-sets for genome assembly and haplotype phasing
JP7457642B2 (ja) 2017-04-03 2024-03-28 ビオンテック ユーエス インコーポレイテッド タンパク質抗原およびその使用
US11793867B2 (en) 2017-12-18 2023-10-24 Biontech Us Inc. Neoantigens and uses thereof
WO2019246286A1 (en) 2018-06-19 2019-12-26 Neon Therapeutics, Inc. Neoantigens and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654183A (en) * 1992-07-27 1997-08-05 California Institute Of Technology Genetically engineered mammalian neural crest stem cells
US5518901A (en) * 1993-04-19 1996-05-21 Murtagh; James J. Methods for adapting nucleic acid for detection, sequencing, and cloning using exonuclease
US5714325A (en) * 1993-09-24 1998-02-03 New England Medical Center Hospitals Prenatal diagnosis by isolation of fetal granulocytes from maternal blood
US5866323A (en) * 1995-04-07 1999-02-02 Case Western Reserve University Cancer diagnosis prognosis and therapy based on mutation of receptors for transforming growth factor β and homologous growth controlling factors
WO1998056952A1 (en) * 1997-06-09 1998-12-17 University Of Southern California A cancer diagnostic method based upon dna methylation differences
US6337392B1 (en) * 1998-05-07 2002-01-08 The Rockefeller University Lens transcriptional control elements and methods of use thereof
US6994971B1 (en) * 1999-10-08 2006-02-07 University Of Utah Research Foundation Particle analysis assay for biomolecular quantification
WO2001035995A2 (en) * 1999-11-19 2001-05-25 Tittle Thomas V Tr3-specific binding agents and methods for their use
CA2412609C (en) * 2000-06-23 2010-09-07 The University Of Chicago Methods for isolating centromere dna
US20030157481A1 (en) * 2001-12-10 2003-08-21 Benjamin Thomas L. Diagnosing and treating cancer cells using T-HR mutants and their targets
AU2002318336A1 (en) * 2001-06-08 2002-12-23 U.S. Genomics, Inc. Methods and products for analyzing nucleic acids based on methylation status
EP1476175A2 (en) * 2002-02-20 2004-11-17 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Hedgehog-related prophylaxis, therapy and diagnosis of gi tract carcinogenesis
DK1400589T3 (da) * 2002-09-18 2006-11-27 Sirs Lab Gmbh Fremgangsmåde til påvisning af prokaryotisk DNA
AU2003900368A0 (en) * 2003-01-24 2003-02-13 Human Genetic Signatures Pty Ltd Assay for nucleic acid molecules
JP3854943B2 (ja) * 2003-05-23 2006-12-06 独立行政法人科学技術振興機構 Ｄｎａメチル化率の測定方法
EP1524523A1 (en) * 2003-10-17 2005-04-20 Deutsches Krebsforschungszentrum Stiftung Des Öffentlichen Rechts Use of ADAM 12 for diagnosis and therapy of preeclampsia
DE602005023710D1 (de) * 2004-02-20 2010-11-04 Japan Science & Tech Agency Dna-array zur analyse der dna-methylierung, konstruktionsverfahren dafür sowie verfahren zur analyse der dna-methylierung

Similar Documents

Publication Publication Date Title
Reeser et al. Validation of a targeted RNA sequencing assay for kinase fusion detection in solid tumors
CN116157533A (zh) 使用杂交方法捕获遗传靶标
CN106029900B (zh) 尿生物标志物群、基因表达特征及其使用方法
US8808990B2 (en) Serial isolation of multiple DNA targets from stool
US11345957B2 (en) Methods of treating glioblastoma in a subject informed by exosomal RNA signatures
CN102757954B (zh) 与冠心病相关的多个基因单核苷酸多态性位点组合及其应用
CN110760936B (zh) 构建dna甲基化文库的方法及其应用
WO2011096926A1 (en) Methods for preparing sequencing libraries
KR20170131516A (ko) 혈액 샘플 내의 순환 종양 세포의 디지털 분석
JP2013178260A5 (enExample)
CN110257382A (zh) 识别肠癌血清标记物的核酸适配体及其筛选方法和用途
WO2020163789A1 (en) Single cell/exosome/vesicle protein profiling
CN108130368A (zh) lncRNA在制备诊断或预示青少年特发性脊柱侧凸产品中的应用
CN110806480B (zh) 肿瘤特异性细胞亚群和特征基因及其应用
TWI500770B (zh) Hoxa9基因作為檢測肝癌生物標記的用途
WO2012019786A1 (en) Method and kit for the diagnosis and/or prognosis of tolerance in liver transplantation
CN114752672B (zh) 基于循环游离DNA突变进行滤泡性淋巴瘤预后评估的检测panel、试剂盒及应用
CN108913772B (zh) 基于捕获测序的bMSI检测技术
CN106282361B (zh) 用于捕获血液病相关基因的基因捕获试剂盒
JP2024519082A (ja) 肝細胞がんのｄｎａメチル化バイオマーカー
CN104651522B (zh) I型胶原α1链的新应用
CN107881228A (zh) 一种与青少年特发性脊柱侧凸相关的分子标记物及其应用
CN104088019A (zh) 一种基于双分子荧光互补技术的肽适配子文库构建方法
WO2025096476A1 (en) Use of multi-nucleotide and structural variants for improved sensitivity and specificity of circulating tumor dna assays
CN115772558A (zh) 一种用于肝衰竭疾病转归预后评价的试剂盒及应用及应用方法