JP2008260707A - 油中水型乳化組成物 - Google Patents
油中水型乳化組成物 Download PDFInfo
- Publication number
- JP2008260707A JP2008260707A JP2007103686A JP2007103686A JP2008260707A JP 2008260707 A JP2008260707 A JP 2008260707A JP 2007103686 A JP2007103686 A JP 2007103686A JP 2007103686 A JP2007103686 A JP 2007103686A JP 2008260707 A JP2008260707 A JP 2008260707A
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- JP
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- Prior art keywords
- water
- emulsion composition
- oil
- component
- oil emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q90/00—Cosmetics or similar toiletry preparations for specific uses not provided for in other groups of this subclass
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
【解決手段】特定の(A)N-長鎖アシル中性アミノ酸エステル(例えば、N-ミリストイル−N-メチル−β−アラニンフィトステリル、N-ミリストイル−N-メチル−β−アラニンデシルテトラデシルから選ばれる1種又は2種),(B)シリコーン油(例えば環状シリコーン油)、(C)水を配合する。(A)成分と(B)成分の重量比が4:96〜90:10かつ(C)成分の重量が組成物に対して0.1〜94.6%であることが好ましい。
【選択図】 なし
Description
〔1〕 (A)下記一般式で( I )で表されるN-長鎖アシル中性アミノ酸エステル(B)シリコーン油、(C)水を含有し、外相が(B)シリコーン油であることを特徴とする油中水型乳化組成物。(但し、一般式( I )において、R1は炭素元素数5〜21の分岐鎖又は直鎖のアルキル基又はアルケニル基を示し、R2は水素原子又は炭素原子数1〜3のアルキル基を示し、R3は水素原子、メチル基又はエチル基、炭素原子数3〜4の分岐鎖若しくは直鎖のアルキル基、又はヒドロキシメチル若しくはヒドロキシエチル基を示し、R4は炭素原子数1〜34の分岐鎖又は直鎖のアルキル基又はアルケニル基、若しくはステロールのアルコール残基を示し、nは0〜2の整数を示す。)
〔3〕 該(A)成分の中性アミノ酸がグリシン、アラニン、N-メチル−β−アラニン、スレオニン、サルコシンのいずれかから選ばれる1種または2種以上であることを特徴とする請求項1〜2の何れかに記載の油中水型乳化組成物。
〔4〕 該(A)成分が、N-ミリストイル−N-メチル−β−アラニンフィトステリル、N-ミリストイル−N-メチル−β−アラニンデシルテトラデシルから選ばれる1種又は2種であることを特徴とする油中水型乳化組成物。
〔5〕 該(B)成分が、環状シリコーン油であることを特徴とする請求項1〜4の何れかに記載の油中水型乳化組成物。
〔6〕請求項1〜5の何れか一項に記載の油中水型乳化組成物を含有する化粧料。
適当な水溶性物質は、例えば、2−フェニルベンズイミダゾール−5−スルホン酸並びにそのアルカリ金属塩、アルカリ土類金属塩、アンモニウム塩、アルキルアンモニウム塩、アルカノールアンモニウム塩およびグルカンモニウム塩;ベンゾフェノンのスルホン酸誘導体、好ましくは2−ヒドロキシ−4−メトキシベンゾフェノン−5−スルホン酸およびその塩;3−ベンジリデンカンファーのスルホン酸誘導体、例えば4−(2−オキソ−3−ボルニリデンメチル)−ベンゼンスルホン酸および2−メチル−5−(2−オキソ−3−ボルニリデン)−スルホン酸並びにそれらの塩などが挙げられる。通常のUV−Aフィルターはとりわけ、ベンゾイルメタン誘導体として、例えば1−(4'−t−ブチルフェニル)−3−(4'−メトキシフェニル)−プロパン−1,3−ジオン、4−t−ブチル−4'−メトキシジベンゾイルメタン(Parsol(登録商標)1789)または1−フェニル−3−(4'−イソプロピルフェニル)−プロパン−1,3−ジオン、およびエナミン化合物などが挙げられる。
下記の表1〜6に記載の配合組成よりなる油中水型乳化組成物(実施例1〜24、比較例1〜12)を調製した。なお、(A)N-長鎖アシル中性アミノ酸エステルとして、N-ミリストイル-N-メチル-β-アラニンフィトステリル及びN-ミリストイル-N-メチル-β-アラニンデシルテトラデシル、(B)シリコーン油として、ドデカメチルシクロヘキサシロキサン(DC246、東レダウコーニングシリコーン株式会社)を用いた。
調製直後、40℃における二週間後及び四週間後の相状態を目視観察し、下記の基準にて安定性評価を行った。
◎:40℃保存四週間後に相分離は認めらない
○:40℃保存四週間後に相分離が認められた
△:40℃保存二週間後に相分離が認められた
×:25℃調製直後に相分離が認められた
調製した油中水型乳化組成物を皮膚に塗布したときの使用感について、専門パネラー3名による官能評価を行い、下記の評価基準に基づいて評価した。3名の評価点の平均値を算出し、0点以上1点未満を×、1点以上2点未満を△、2点以上3点未満を○、3点以上4点以下を◎とした。
4点:非常になめらかで良好な油中水型乳化組成物である。
3点:なめらかで良好な油中水型乳化組成物である。
2点:ややなめらかな油中水型乳化組成物である。
1点:やや硬く伸びの悪い油中水型乳化組成物である。
0点:非常に硬く伸びの悪い油中水型乳化組成物または、相分離等油中水型乳化組成物の形状を有しない。
下記の表6に記載の配合組成よりなる油中水型乳化組成物(実施例25〜26)を調製し、表1〜5と同様の評価を行った。なお、(B)シリコーン油として、デカメチルシクロペンタシロキサン(SH245、東レダウコーニングシリコーン株式会社)を用いた。
下記表7〜9に示すンスクリーン処方を常法に従って作成したところ、いずれも良好な使用感と保存安定性を得ることができた。
表10〜37に処方例を開示する。
〔1〕 (A)下記一般式で( I )で表されるN-長鎖アシル中性アミノ酸エステル(B)シリコーン油、(C)水を含有し、外相が(B)シリコーン油であることを特徴とする油中水型乳化組成物。(但し、一般式( I )において、R1は炭素元素数5〜21の分岐鎖又は直鎖のアルキル基又はアルケニル基を示し、R2は水素原子又は炭素原子数1〜3のアルキル基を示し、R3は水素原子、メチル基又はエチル基、炭素原子数3〜4の分岐鎖若しくは直鎖のアルキル基、又はヒドロキシメチル若しくはヒドロキシエチル基を示し、R4は炭素原子数1〜34の分岐鎖又は直鎖のアルキル基又はアルケニル基、若しくはステロールのアルコール残基を示し、nは0〜2の整数を示す。)
〔3〕 該(A)成分の中性アミノ酸がグリシン、アラニン、N-メチル−β−アラニン、スレオニン、サルコシンのいずれかから選ばれる1種または2種以上であることを特徴とする請求項1〜2の何れかに記載の油中水型乳化組成物。
〔4〕 該(A)成分が、N-ミリストイル−N-メチル−β−アラニンフィトステリル、N-ミリストイル−N-メチル−β−アラニンデシルテトラデシルから選ばれる1種又は2種であることを特徴とする請求項1〜3の何れかに記載の油中水型乳化組成物。
〔5〕 該(B)成分が、環状シリコーン油であることを特徴とする請求項1〜4の何れかに記載の油中水型乳化組成物。
〔6〕請求項1〜5の何れか一項に記載の油中水型乳化組成物を含有する化粧料。
下記の表1〜5に記載の配合組成よりなる油中水型乳化組成物(実施例1〜24、比較例1〜12)を調製した。なお、(A)N-長鎖アシル中性アミノ酸エステルとして、N-ミリストイル-N-メチル-β-アラニンフィトステリル及びN-ミリストイル-N-メチル-β-アラニンデシルテトラデシル、(B)シリコーン油として、ドデカメチルシクロヘキサシロキサン(DC246、東レダウコーニングシリコーン株式会社)を用いた。
下記の表6に記載の配合組成よりなる油中水型乳化組成物(実施例25〜30)を調製し、表1〜5と同様の評価を行った。なお、(B)シリコーン油として、デカメチルシクロペンタシロキサン(SH245、東レダウコーニングシリコーン株式会社)を用いた。
〔1〕 (A)下記一般式で( I )で表されるN-長鎖アシル中性アミノ酸エステル(B)シリコーン油、(C)水を含有し、外相が(B)シリコーン油であることを特徴とする油中水型乳化組成物。(但し、一般式( I )において、R1は炭素元素数5〜21の分岐鎖又は直鎖のアルキル基又はアルケニル基を示し、R2は水素原子又は炭素原子数1〜3のアルキル基を示し、R3は水素原子、メチル基又はエチル基、炭素原子数3〜4の分岐鎖若しくは直鎖のアルキル基、又はヒドロキシメチル若しくはヒドロキシエチル基を示し、R4は炭素原子数1〜34の分岐鎖又は直鎖のアルキル基又はアルケニル基、若しくはステロールのアルコール残基を示し、nは0〜2の整数を示す。)
〔3〕 該(A)成分の中性アミノ酸がグリシン、アラニン、N-メチル−β−アラニン、スレオニン、サルコシンのいずれかから選ばれる1種または2種以上であることを特徴とする請求項1〜2の何れかに記載の油中水型乳化組成物。
〔4〕 該(A)成分が、N-ミリストイル−N-メチル−β−アラニンフィトステリル、N-ミリストイル−N-メチル−β−アラニンデシルテトラデシルから選ばれる1種又は2種であることを特徴とする請求項1〜3の何れかに記載の油中水型乳化組成物。
〔5〕 該(B)成分が、環状シリコーン油であることを特徴とする請求項1〜4の何れかに記載の油中水型乳化組成物。
〔6〕請求項1〜5の何れか一項に記載の油中水型乳化組成物を含有する化粧料。
Claims (6)
- (A)下記一般式で( I )で表されるN-長鎖アシル中性アミノ酸エステル(B)シリコーン油、(C)水を含有することを特徴とする油中水型乳化組成物。(但し、一般式( I )において、R1は炭素元素数5〜21の分岐鎖又は直鎖のアルキル基又はアルケニル基を示し、R2は水素原子又は炭素原子数1〜3のアルキル基を示し、R3は水素原子、メチル基又はエチル基、炭素原子数3〜4の分岐鎖若しくは直鎖のアルキル基、又はヒドロキシメチル若しくはヒドロキシエチル基を示し、R4は炭素原子数1〜34の分岐鎖又は直鎖のアルキル基又はアルケニル基、若しくはステロールのアルコール残基を示し、nは0〜2の整数を示す。)
- (A)成分と(B)成分の重量比が4:96〜90:10かつ(C)成分の重量が組成物に対して0.1〜94.6%であることを特徴とする請求項1に記載の油中水型乳化組成物。
- 該(A)成分の中性アミノ酸がグリシン、アラニン、N-メチル−β−アラニン、スレオニン、サルコシンのいずれかから選ばれる1種または2種以上であることを特徴とする請求項1〜2の何れかに記載の油中水型乳化組成物。
- 該(A)成分が、N-ミリストイル−N-メチル−β−アラニンフィトステリル、N-ミリストイル−N-メチル−β−アラニンデシルテトラデシルから選ばれる1種又は2種であることを特徴とする油中水型乳化組成物。
- 該(B)成分が、環状シリコーン油であることを特徴とする請求項1〜4の何れかに記載の油中水型乳化組成物。
- 請求項1〜5の何れか一項に記載の油中水型乳化組成物を含有する化粧料。
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FR0852460A FR2914852B1 (fr) | 2007-04-11 | 2008-04-11 | Composition emulsifiee de type eau-dans-huile et cosmetique la comprenant |
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JP2012072064A (ja) * | 2010-09-27 | 2012-04-12 | Fancl Corp | 油中水型乳化組成物 |
JP2013221007A (ja) * | 2012-04-16 | 2013-10-28 | Ajinomoto Co Inc | ステロールエステルを含有する組成物 |
JP2014015425A (ja) * | 2012-07-10 | 2014-01-30 | Shiseido Co Ltd | 油中水型乳化化粧料 |
JP2016000745A (ja) * | 2015-08-06 | 2016-01-07 | ロレアル | 水和能力が強化された組成物 |
JP2020015677A (ja) * | 2018-07-24 | 2020-01-30 | ロート製薬株式会社 | コレステロール及び/又はフィトステロールを含有する外用組成物 |
JP2020083844A (ja) * | 2018-11-29 | 2020-06-04 | 味の素株式会社 | N−アシル中性アミノ酸エステル含有組成物 |
JP7196571B2 (ja) | 2018-11-29 | 2022-12-27 | 味の素株式会社 | N-アシル中性アミノ酸エステル含有組成物 |
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JP5666763B2 (ja) | 2015-02-12 |
FR2914852A1 (fr) | 2008-10-17 |
CN101283960B (zh) | 2013-03-06 |
US20080280865A1 (en) | 2008-11-13 |
FR2914852B1 (fr) | 2013-03-08 |
CN101283960A (zh) | 2008-10-15 |
US8303968B2 (en) | 2012-11-06 |
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