JP2008018976A - 多層容器、多層容器の液剤収納方法、及び多層容器の処理装置 - Google Patents
多層容器、多層容器の液剤収納方法、及び多層容器の処理装置 Download PDFInfo
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Abstract
【解決手段】
本発明の多層容器は、収納される液剤に対して加熱加湿による所要の滅菌処理が施される多層容器であって、エチレン−ビニルアルコール共重合体(EVOH)からなる中間層と、オレフィン系樹脂材からなる内側層及び外側層とからなり、前記液剤と共に当該多層容器を前記滅菌処理後に冷却させ、さらにその冷却後に加熱乾燥されることを特徴とする。滅菌中にエチレン−ビニルアルコール共重合体に吸収された水分を短時間に除去し、ガスバリア性と透明度を急速に回復させることができる。
【選択図】 図1
Description
11 多層構造フィルム
12 液剤室
13 透穴部
14 ポート
15 蓋部
16、17 端部
21 内側層
22 接着層
23 中間層
24 接着層
25 外側層
30 処理装置
31 処理槽
32 フレーム
33 蓋部
34 熱交換器
35 貯水槽
36 温水槽
40 多層容器
41 トレー
60 キットバック
62 液剤収納室
63 製剤収納室
64 ヒートシール
65 ポート
66 孔部
67 シール部
71 多層容器
72 溶着部
73 収納室
74 孔
75 下端部
76 ポート
78 延長部
79 上端部
Claims (18)
- 収納される液剤に対して加熱加湿による所要の滅菌処理が施される多層容器であって、エチレン−ビニルアルコール共重合体からなる中間層と、オレフィン系樹脂材からなる内側層及び外側層とからなり、前記液剤と共に当該多層容器を前記滅菌処理後に冷却させ、さらにその冷却後に加熱乾燥されることを特徴とする多層容器。
- 前記中間層と前記内側層および前記外側層の間には、接着層が形成されることを特徴とする請求項1記載の多層容器。
- 前記エチレン−ビニルアルコール共重合体からなる中間層と前記接着層を併せた層厚を容器を構成するフィルム全体の肉厚の1/6〜1/10とすることを特徴とする請求項2記載の多層容器。
- 前記液剤は酸化しやすい液からなり、前記液剤の充填時に前記液剤の酸素を取り除き若しくは窒素等の不活性ガスに95%以上置換させて充填してなることを特徴とする請求項1記載の多層容器。
- 前記滅菌処理は、90℃以上の高圧高温下で行われることを特徴とする請求項1記載の多層容器。
- 前記加熱乾燥は温度が50℃以上100℃以下で且つ低湿度で行なわれることを特徴とする請求項1記載の多層容器。
- 前記冷却後の加熱乾燥処理を行う処理装置中の空気は不活性ガスに置換されてなることを特徴とする請求項1記載の多層容器。
- 前記多層容器の前記内層は、ポリエチレンまたはポリプロピレン系樹脂からなり、前記多層容器の前記外層は、ポリエチレン、ポリプロピレン、ポリエステル、またはポリブチレンテレフタレート系樹脂からなることを特徴とする請求項1記載の多層容器。
- 前記多層容器は、ポート部を有して形成される単室若しくは複室の容器、或いは外側に樹脂製の外装部を有する容器であることを特徴とする請求項1記載の多層容器。
- 前記ポート部を当該多層容器の外層を構成するオレフィン系樹脂材で覆った事を特徴とする請求項9記載の多層容器。
- 前記多層容器は液剤用室と抗生物質用室に分けられる複室の容器であり、前記滅菌処理は、前記抗生物質用室は空で滅菌処理を行い乾燥処理中には空のままの抗生物質用室を乾燥させることを特徴とする請求項1記載の多層容器。
- エチレン−ビニルアルコール共重合体からなる中間層とオレフィン系樹脂材からなる内側層及び外側層とからなり所要の液剤を収納する多層容器に、前記液剤を当該多重容器に充填した後に加熱加湿によって滅菌処理を施し、前記多層容器を冷却させ、さらにその冷却後に加熱乾燥を施すことを特徴とする多層容器の液剤収納方法。
- 前記液剤の充填時に前記液剤の酸素を取り除き若しくは窒素等の不活性ガスに95%以上置換させて充填してなることを特徴とする請求項12記載の多層容器の液剤収納方法。
- 前記滅菌処理は、90℃以上の高圧高温下で行われることを特徴とする請求項12記載の多層容器の液剤収納方法。
- 前記加熱乾燥は温度が50℃以上100℃以下で且つ低湿度で行なわれることを特徴とする請求項12記載の多層容器の液剤収納方法。
- 前記冷却後の加熱乾燥処理を行う処理装置中の空気は不活性ガスに置換されてなることを特徴とする請求項12記載の多層容器の液剤収納方法。
- エチレン−ビニルアルコール共重合体からなる中間層とオレフィン系樹脂材からなる内側層及び外側層とからなり所要の液剤を収納する多層容器に、前記液剤を当該多重容器に充填した後に加熱加湿によって滅菌処理を施し、前記多層容器を冷却させ、さらにその冷却後に加熱乾燥を施すことを連続的に行うことを特徴とする多層容器の処理装置。
- 当該処理装置中の多層容器周りのガスは不活性ガスに置換されてなることを特徴とする請求項17記載の多層容器の処理装置。
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JP2013074928A (ja) * | 2011-09-13 | 2013-04-25 | Kyoraku Co Ltd | プラスチック製バイアル |
WO2022054887A1 (ja) * | 2020-09-10 | 2022-03-17 | 株式会社クラレ | 多層構造体、およびそれからなる包装容器 |
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JPS60159043A (ja) * | 1984-01-31 | 1985-08-20 | 東洋製罐株式会社 | 密封容器の製造方法 |
JPS62122923A (ja) * | 1985-11-13 | 1987-06-04 | 住友ベークライト株式会社 | 包装体の製造方法 |
JPH1080464A (ja) * | 1996-09-06 | 1998-03-31 | Material Eng Tech Lab Inc | ガスバリアー性を有する輸液容器 |
JP2005304911A (ja) * | 2004-04-23 | 2005-11-04 | Inter Medic Kk | 医療用複室容器及びその製造方法 |
JP2006507914A (ja) * | 2002-11-28 | 2006-03-09 | 株式会社大塚製薬工場 | 医療用複室容器及びその製造方法 |
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JPS60159043A (ja) * | 1984-01-31 | 1985-08-20 | 東洋製罐株式会社 | 密封容器の製造方法 |
JPS62122923A (ja) * | 1985-11-13 | 1987-06-04 | 住友ベークライト株式会社 | 包装体の製造方法 |
JPH1080464A (ja) * | 1996-09-06 | 1998-03-31 | Material Eng Tech Lab Inc | ガスバリアー性を有する輸液容器 |
JP2006507914A (ja) * | 2002-11-28 | 2006-03-09 | 株式会社大塚製薬工場 | 医療用複室容器及びその製造方法 |
JP2005304911A (ja) * | 2004-04-23 | 2005-11-04 | Inter Medic Kk | 医療用複室容器及びその製造方法 |
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JP2013074928A (ja) * | 2011-09-13 | 2013-04-25 | Kyoraku Co Ltd | プラスチック製バイアル |
WO2022054887A1 (ja) * | 2020-09-10 | 2022-03-17 | 株式会社クラレ | 多層構造体、およびそれからなる包装容器 |
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