JP2007535519A5 - - Google Patents

Info

Publication number

JP2007535519A5

JP2007535519A5 JP2007509994A JP2007509994A JP2007535519A5 JP 2007535519 A5 JP2007535519 A5 JP 2007535519A5 JP 2007509994 A JP2007509994 A JP 2007509994A JP 2007509994 A JP2007509994 A JP 2007509994A JP 2007535519 A5 JP2007535519 A5 JP 2007535519A5

Authority

JP

Japan

Prior art keywords

package

days

period

dosing cycle

additional dosing

Prior art date

2005-04-29

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• Global Dossier
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• BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 claims 11
• BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 claims 11
• 229960002568 ethinylestradiol Drugs 0.000 claims 11
• RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 10
• METQSPRSQINEEU-UHFFFAOYSA-N dihydrospirorenone Natural products CC12CCC(C3(CCC(=O)C=C3C3CC33)C)C3C1C1CC1C21CCC(=O)O1 METQSPRSQINEEU-UHFFFAOYSA-N 0.000 claims 10
• 229960004845 drospirenone Drugs 0.000 claims 10
• METQSPRSQINEEU-HXCATZOESA-N drospirenone Chemical compound C([C@]12[C@H]3C[C@H]3[C@H]3[C@H]4[C@@H]([C@]5(CCC(=O)C=C5[C@@H]5C[C@@H]54)C)CC[C@@]31C)CC(=O)O2 METQSPRSQINEEU-HXCATZOESA-N 0.000 claims 10
• 239000000583 progesterone congener Substances 0.000 claims 10
• 230000000740 bleeding effect Effects 0.000 claims 9
• 229940011871 estrogen Drugs 0.000 claims 9
• 239000000262 estrogen Substances 0.000 claims 9
• AZFLJNIPTRTECV-FUMNGEBKSA-N dienogest Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@](CC3)(O)CC#N)CC3)C3=C21 AZFLJNIPTRTECV-FUMNGEBKSA-N 0.000 claims 5
• 229960003309 dienogest Drugs 0.000 claims 5
• WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 claims 3
• -1 guestden Chemical compound 0.000 claims 3
• 229960004400 levonorgestrel Drugs 0.000 claims 3
• 229930182833 estradiol Natural products 0.000 claims 2
• 229960005309 estradiol Drugs 0.000 claims 2
• 229940068196 placebo Drugs 0.000 claims 2
• 239000000902 placebo Substances 0.000 claims 2
• VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 1
• 208000002874 Acne Vulgaris Diseases 0.000 claims 1
• 208000005171 Dysmenorrhea Diseases 0.000 claims 1
• 206010013935 Dysmenorrhoea Diseases 0.000 claims 1
• 201000009273 Endometriosis Diseases 0.000 claims 1
• IMONTRJLAWHYGT-ZCPXKWAGSA-N Norethindrone Acetate Chemical compound C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@](C#C)(OC(=O)C)[C@@]1(C)CC2 IMONTRJLAWHYGT-ZCPXKWAGSA-N 0.000 claims 1
• 206010000496 acne Diseases 0.000 claims 1
• 239000003433 contraceptive agent Substances 0.000 claims 1
• 230000002254 contraceptive effect Effects 0.000 claims 1
• 229960000978 cyproterone acetate Drugs 0.000 claims 1
• UWFYSQMTEOIJJG-FDTZYFLXSA-N cyproterone acetate Chemical compound C1=C(Cl)C2=CC(=O)[C@@H]3C[C@@H]3[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(C)=O)(OC(=O)C)[C@@]1(C)CC2 UWFYSQMTEOIJJG-FDTZYFLXSA-N 0.000 claims 1
• 229960004976 desogestrel Drugs 0.000 claims 1
• RPLCPCMSCLEKRS-BPIQYHPVSA-N desogestrel Chemical compound C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 RPLCPCMSCLEKRS-BPIQYHPVSA-N 0.000 claims 1
• GCKFUYQCUCGESZ-BPIQYHPVSA-N etonogestrel Chemical compound O=C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 GCKFUYQCUCGESZ-BPIQYHPVSA-N 0.000 claims 1
• 229940124566 female contraceptive agent Drugs 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 229960001652 norethindrone acetate Drugs 0.000 claims 1
• 229960000417 norgestimate Drugs 0.000 claims 1
• KIQQMECNKUGGKA-NMYWJIRASA-N norgestimate Chemical compound O/N=C/1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(OC(C)=O)C#C)[C@@H]4[C@@H]3CCC2=C\1 KIQQMECNKUGGKA-NMYWJIRASA-N 0.000 claims 1
• 201000010065 polycystic ovary syndrome Diseases 0.000 claims 1
• 208000024891 symptom Diseases 0.000 claims 1
• JUNDJWOLDSCTFK-MTZCLOFQSA-N trimegestone Chemical compound C1CC2=CC(=O)CCC2=C2[C@@H]1[C@@H]1CC[C@@](C(=O)[C@@H](O)C)(C)[C@@]1(C)CC2 JUNDJWOLDSCTFK-MTZCLOFQSA-N 0.000 claims 1
• 229950008546 trimegestone Drugs 0.000 claims 1