EA031227B1 - Способ пероральной контрацепции у женщин, способ профилактики нежелательных кровотечений в течение пероральной контрацепции у женщин и фармацевтический набор для применения в этих способах - Google Patents

Способ пероральной контрацепции у женщин, способ профилактики нежелательных кровотечений в течение пероральной контрацепции у женщин и фармацевтический набор для применения в этих способах Download PDF

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Publication number
EA031227B1
EA031227B1 EA201200377A EA201200377A EA031227B1 EA 031227 B1 EA031227 B1 EA 031227B1 EA 201200377 A EA201200377 A EA 201200377A EA 201200377 A EA201200377 A EA 201200377A EA 031227 B1 EA031227 B1 EA 031227B1
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break
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specified
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EA201200377A
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Russian (ru)
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EA201200377A8 (ru
EA201200377A1 (ru
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Андреас Заксе
Патриция Дж. Сулак
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Байер Интеллекчуал Проперти Гмбх
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Application filed by Байер Интеллекчуал Проперти Гмбх filed Critical Байер Интеллекчуал Проперти Гмбх
Publication of EA201200377A1 publication Critical patent/EA201200377A1/ru
Publication of EA201200377A8 publication Critical patent/EA201200377A8/ru
Publication of EA031227B1 publication Critical patent/EA031227B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)
EA201200377A 2004-04-30 2005-04-29 Способ пероральной контрацепции у женщин, способ профилактики нежелательных кровотечений в течение пероральной контрацепции у женщин и фармацевтический набор для применения в этих способах EA031227B1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56644304P 2004-04-30 2004-04-30
US57502404P 2004-05-28 2004-05-28
US57719904P 2004-06-07 2004-06-07
US63838004P 2004-12-27 2004-12-27
US66006805P 2005-03-10 2005-03-10

Publications (3)

Publication Number Publication Date
EA201200377A1 EA201200377A1 (ru) 2012-08-30
EA201200377A8 EA201200377A8 (ru) 2018-01-31
EA031227B1 true EA031227B1 (ru) 2018-12-28

Family

ID=35056905

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201200377A EA031227B1 (ru) 2004-04-30 2005-04-29 Способ пероральной контрацепции у женщин, способ профилактики нежелательных кровотечений в течение пероральной контрацепции у женщин и фармацевтический набор для применения в этих способах
EA200601908A EA016625B1 (ru) 2004-04-30 2005-04-29 Способ контроля прорывных кровотечений при пролонгированном режиме приема гормональных контрацептивов

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA200601908A EA016625B1 (ru) 2004-04-30 2005-04-29 Способ контроля прорывных кровотечений при пролонгированном режиме приема гормональных контрацептивов

Country Status (29)

Country Link
US (3) US8163721B2 (enExample)
EP (1) EP1747001B1 (enExample)
JP (4) JP2007535519A (enExample)
KR (4) KR20130022425A (enExample)
CN (1) CN103127156A (enExample)
AR (1) AR048722A1 (enExample)
AU (1) AU2005237255B2 (enExample)
BR (1) BRPI0510493A (enExample)
CA (1) CA2562296A1 (enExample)
CR (1) CR8709A (enExample)
DK (1) DK1747001T3 (enExample)
EA (2) EA031227B1 (enExample)
EC (1) ECSP066999A (enExample)
ES (1) ES2704999T3 (enExample)
HU (1) HUE041475T2 (enExample)
IL (1) IL178458A (enExample)
LT (1) LT1747001T (enExample)
MX (1) MXPA06012567A (enExample)
MY (1) MY151322A (enExample)
NO (1) NO341685B1 (enExample)
NZ (1) NZ586107A (enExample)
PA (1) PA8631801A1 (enExample)
PE (1) PE20060467A1 (enExample)
SG (2) SG10201701904TA (enExample)
SI (1) SI1747001T1 (enExample)
SV (1) SV2006002100A (enExample)
TW (1) TWI374735B (enExample)
UY (1) UY28875A1 (enExample)
WO (1) WO2005105103A2 (enExample)

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MY151322A (en) * 2004-04-30 2014-05-15 Bayer Ip Gmbh Management of breakthrough bleeding in extended hormonal contraceptive regimens
US20070111975A1 (en) 2004-10-07 2007-05-17 Duramed Pharmaceuticals, Inc. Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens
US20070088010A1 (en) * 2005-10-17 2007-04-19 Doris Huebler Method of making a single-stage pharmaceutical preparation for oral therapy of dysfunctional uterine bleeding, containing ethinyl estradiol and dienogest
EP1977752A1 (de) * 2007-03-01 2008-10-08 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Zubereitung zur Verminderung der Endometriose
DE102007011105A1 (de) * 2007-03-02 2008-09-04 Bayer Schering Pharma Aktiengesellschaft Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose
KR20110045065A (ko) * 2008-09-16 2011-05-03 플레이텍스 프로덕츠, 엘엘씨. 월경 억제, 피임 및 호르몬 대체 요법을 위한 약제 및 이를 투여하는 방법
US9192614B2 (en) 2008-10-08 2015-11-24 Agile Therapeutics, Inc. Contraceptive transdermal delivery of hormones
WO2010042612A1 (en) 2008-10-08 2010-04-15 Agile Therapeutics, Inc. Transdermal delivery
EP2343963B1 (en) 2008-10-08 2019-04-10 Agile Therapeutics, Inc. Transdermal delivery
EP2410859A4 (en) 2009-03-27 2013-03-13 Agile Therapeutics Inc TRANSDERMAL ADMINISTRATION
US11351122B1 (en) 2010-07-28 2022-06-07 Laboratorios Leon Farma Sa Synthetic progestogens and pharmaceutical compositions comprising the same
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
US9603860B2 (en) 2010-07-28 2017-03-28 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
US10888518B2 (en) 2015-06-18 2021-01-12 Estetra Sprl Orodispersible tablet containing estetrol
US10894014B2 (en) 2015-06-18 2021-01-19 Estetra Sprl Orodispersible tablet containing Estetrol
GEP20217243B (en) 2015-06-18 2021-04-26 Sprl Estetra Orodispersible dosage unit containing an estetrol component
JP6863547B2 (ja) 2015-06-18 2021-04-21 エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ エステトロール成分を含有する口腔内崩壊性投与単位
CN113750108B (zh) * 2015-06-23 2025-08-19 莱昂实验室制药股份有限公司 用于过重女性患者的基于屈螺酮的避孕药
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
FI3518933T4 (fi) 2016-09-30 2025-05-14 Sumitomo Pharma Switzerland Gmbh Menetelmiä kohtumyooman ja endometrioosin hoitamiseksi
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
US12138270B2 (en) 2021-09-07 2024-11-12 Millicent Pharma Limited Contraceptive regimen including reduced level of estrogen

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WO1998004269A1 (en) * 1996-07-26 1998-02-05 American Home Products Corporation Monophasic contraceptive method and kit comprising a combination of a progestin and estrogen
US6451778B1 (en) * 1996-07-26 2002-09-17 Wyeth Oral contraceptive
EP0911029A2 (en) * 1997-06-23 1999-04-28 Medical College Of Hampton Roads Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy
US6500814B1 (en) * 1997-09-11 2002-12-31 Wyeth Pharmaceuticals Hormonal contraceptive
US20030119798A1 (en) * 1999-08-31 2003-06-26 Schering Aktiengesellschaft Pharmaceutical composition for use as a contraceptive
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JENAPHARM: "NEUES PERIODENSYSTEM MIT VALETTE", JENAPHARM, March 2004 (2004-03), XP002350231, the whole document *
ROSENBERG, M. WAUGH, M.S.: "Causes and consequences of oral contraceptive noncompliance", AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY, MOSBY, ST LOUIS, MO, US, vol. 180, no. 2, 1 February 1999 (1999-02-01), US, pages S276 - S279, XP005179066, ISSN: 0002-9378 *
SILLEM M, ET AL.: "USE OF AN ORAL CONTRACEPTIVE CONTAINING DROSPIRENONE IN AN EXTENDED REGIMEN", EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, PARTHENON PUBLISHING GROUP, CARNFOORTH, GB, vol. 08, no. 03, 1 September 2003 (2003-09-01), GB, pages 162 - 169, XP008064769, ISSN: 1362-5187 *
WIEGRATZ I,ET AL.: "Attitude of German women and gynecologists towards long-cycle treatment with oral contraceptives", CONTRACEPTION., GERON-X, INC., LOS ALTOS, CA., US, vol. 69, no. 1, 1 January 2004 (2004-01-01), US, pages 37 - 42, XP002353728, ISSN: 0010-7824, DOI: 10.1016/j.contraception.2003.09.004 *

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Publication number Publication date
EA201200377A8 (ru) 2018-01-31
JP2013018787A (ja) 2013-01-31
US20050250747A1 (en) 2005-11-10
US20120202779A1 (en) 2012-08-09
AU2005237255A1 (en) 2005-11-10
ES2704999T3 (es) 2019-03-21
IL178458A (en) 2016-08-31
PA8631801A1 (es) 2006-11-09
JP2007535519A (ja) 2007-12-06
SI1747001T1 (sl) 2019-02-28
UY28875A1 (es) 2005-11-30
NO341685B1 (no) 2017-12-18
TWI374735B (en) 2012-10-21
BRPI0510493A (pt) 2007-11-13
NZ586107A (en) 2012-05-25
NO20065499L (no) 2006-11-29
CN103127156A (zh) 2013-06-05
KR20150058555A (ko) 2015-05-28
IL178458A0 (en) 2008-04-13
WO2005105103A2 (en) 2005-11-10
EP1747001B1 (en) 2018-10-10
KR101812160B1 (ko) 2017-12-27
JP6153967B2 (ja) 2017-06-28
KR20070004919A (ko) 2007-01-09
JP2015187157A (ja) 2015-10-29
SV2006002100A (es) 2006-02-15
AU2005237255B2 (en) 2011-07-07
CR8709A (es) 2007-08-28
TW200603781A (en) 2006-02-01
ECSP066999A (es) 2006-12-29
KR20160150113A (ko) 2016-12-28
MY151322A (en) 2014-05-15
HUE041475T2 (hu) 2019-05-28
MXPA06012567A (es) 2006-12-15
EA200601908A1 (ru) 2007-04-27
PE20060467A1 (es) 2006-06-11
US8163721B2 (en) 2012-04-24
SG152288A1 (en) 2009-05-29
DK1747001T3 (en) 2019-02-04
LT1747001T (lt) 2019-01-25
WO2005105103A3 (en) 2006-09-08
JP2017048253A (ja) 2017-03-09
AR048722A1 (es) 2006-05-17
SG10201701904TA (en) 2017-05-30
KR20130022425A (ko) 2013-03-06
EA016625B1 (ru) 2012-06-29
JP6134491B2 (ja) 2017-05-24
CA2562296A1 (en) 2005-11-10
US20150174142A1 (en) 2015-06-25
EA201200377A1 (ru) 2012-08-30
EP1747001A2 (en) 2007-01-31

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